452 research outputs found
Simultaneous existence of two spin-wave modes in ultrathin Fe/GaAs(001) films studied by Brillouin Light Scattering: experiment and theory
A double-peaked structure was observed in the {\it in-situ} Brillouin Light
Scattering (BLS) spectra of a 6 \AA thick epitaxial Fe/GaAs(001) film for
values of an external magnetic field , applied along the hard in plane
direction, lower than a critical value kOe. This experimental
finding is theoretically interpreted in terms of a model which assumes a
non-homogeneous magnetic ground state characterized by the presence of
perperpendicular up/down stripe domains. For such a ground state, two spin-wave
modes, namely an acoustic and an optic mode, can exist. Upon increasing the
field the magnetization tilts in the film plane, and for the
ground state is homogeneous, thus allowing the existence of just a single
spin-wave mode. The frequencies of the two spin-wave modes were calculated and
successfully compared with the experimental data. The field dependence of the
intensities of the corresponding two peaks that are present in the BLS spectra
was also estimated, providing further support to the above-mentioned
interpretation.Comment: Shortened version (7 pages). Accepted for publication in Physical
Review
Sudan Black B treatment reduces autofluorescence and improves resolution of in situ hybridization specific fluorescent signals of brain sections
Interference by autofluorescence is one of the major concerns of immunofluorescence analysis of in situ hybridization-based diagnostic assays. We present a useful technique that reduces autofluorescent background without affecting the tissue integrity or direct immunofluorescence signals in brain sections. Using six different protocols, such as ammonia/ethanol, Sudan Black B (SBB) in 70% ethanol, photobleaching with UV light and different combinations of them in both formalin-fixed paraffin-embedded and frozen human brain tissue sections, we have found that tissue treatment of SBB in a concentration of 0.1% in 70% ethanol is the best approach to reduce/eliminate tissue autofluorescence and background, while preserving the specific fluorescence hybridization signals. This strategy is a feasible, non-time consuming method that provides a reasonable compromise between total reduction of the tissue autofluorescence and maintenance of specific fluorescent labels.Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)[2007/56146-2]Comissao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)[1429/08-6
Assessment of the interplay between blood and skin vascular abnormalities in adult purpura fulminans
RATIONALE: Purpura fulminans in adults is a rare but devastating disease. Its pathophysiology is not well known. OBJECTIVES: To understand the pathophysiology of skin lesions in purpura fulminans, the interplay between circulating blood and vascular alterations was assessed. METHODS: Prospective multicenter study in four intensive care units. Patients with severe sepsis without skin lesions were recruited as control subjects. MEASUREMENTS AND MAIN RESULTS: Twenty patients with severe sepsis and purpura fulminans were recruited for blood sampling, and skin biopsy was performed in deceased patients. High severity of disease and mortality rates (80%) was observed. Skin biopsies in purpura fulminans lesions revealed thrombosis and extensive vascular damage: vascular congestion and dilation, endothelial necrosis, alteration of markers of endothelial integrity (CD31) and of the protein C pathway receptors (endothelial protein C receptor, thrombomodulin). Elevated plasminogen activating inhibitor-1 mRNA was also observed. Comparison with control patients showed that these lesions were specific to purpura fulminans. By contrast, no difference was observed for blood hemostasis parameters, including soluble thrombomodulin, activated protein C, and disseminated intravascular coagulation markers. Bacterial presence at the vascular wall was observed specifically in areas of vascular damage in eight of nine patients tested (including patients with Streptococcus pneumoniae, Neisseria meningitidis, Escherichia coli, and Pseudomonas aeruginosa infection). CONCLUSIONS: Thrombi and extensive vascular damage with multifaceted prothrombotic local imbalance are characteristics of purpura fulminans. A "vascular wall infection" hypothesis, responsible for endothelial damage and subsequent skin lesions, can be put forward
Mood Disorder Due to a General Medical Condition with Manic Features
This case report describes a patient with manic and psychotic symptoms who had a history of neurocysticercosis and presented with an episode of hypertensive hydrocephalus in 2003. Despite her history, she was initially treated for primary psychiatric disease
Spectrally resolved observations of atmospheric emitted radiance in the H2O rotation band
This paper presents the project Earth Cooling by Water
Vapor Radiation, an observational programme, which aims at
developing a database of spectrally resolved far infrared
observations, in atmospheric dry conditions, in order to
validate radiative transfer models and test the quality of water
vapor continuum and line parameters. The project provides
the very first set of far-infrared spectral downwelling
radiance measurements, in dry atmospheric conditions,
which are complemented with Raman Lidar-derived
temperature and water vapor profiles
The relative importance of phytoplankton aggregates and zooplankton fecal pellets to carbon export: insights from free-drifting sediment trap deployments in naturally iron-fertilised waters near the Kerguelen Plateau
The first KErguelen Ocean and Plateau compared Study (KEOPS1), conducted in the naturally iron-fertilised Kerguelen bloom, demonstrated that fecal material was the main pathway for exporting carbon to the deep ocean during summer (January–February 2005), suggesting a limited role of direct export via phytodetrital aggregates. The KEOPS2 project reinvestigated this issue during the spring bloom initiation (October–November 2011), when zooplankton communities may exert limited grazing pressure, and further explored the link between carbon flux, export efficiency and dominant sinking particles depending upon surface plankton community structure. Sinking particles were collected in polyacrylamide gel-filled and standard free-drifting sediment traps (PPS3/3), deployed at six stations between 100 and 400 m, to examine flux composition, particle origin and their size distributions. Results revealed an important contribution of phytodetrital aggregates (49 ± 10 and 45 ± 22% of the total number and volume of particles respectively, all stations and depths averaged). This high contribution dropped when converted to carbon content (30 ± 16% of total carbon, all stations and depths averaged), with cylindrical fecal pellets then representing the dominant fraction (56 ± 19%).At 100 and 200 m depth, iron- and biomass-enriched sites exhibited the highest carbon fluxes (maxima of 180 and 84 ± 27 mg C m-2 d-1, based on gel and PPS3/3 trap collection respectively), especially where large fecal pellets dominated over phytodetrital aggregates. Below these depths, carbon fluxes decreased (48 ± 21% decrease on average between 200 and 400 m), and mixed aggregates composed of phytodetritus and fecal matter dominated, suggesting an important role played by physical aggregation in deep carbon export.Export efficiencies determined from gels, PPS3/3 traps and 234Th disequilibria (200 m carbon flux/net primary productivity) were negatively correlated to net primary productivity with observed decreases from ~ 0.2 at low-iron sites to ~ 0.02 at high-iron sites. Varying phytoplankton communities and grazing pressure appear to explain this negative relationship. Our work emphasises the need to consider detailed plankton communities to accurately identify the controls on carbon export efficiency, which appear to include small spatio-temporal variations in ecosystem structure
Absence of stable collinear configurations in Ni(001)ultrathin films: canted domain structure as ground state
Brillouin light scattering (BLS) measurements were performed for (17-120)
Angstrom thick Cu/Ni/Cu/Si(001) films. A monotonic dependence of the frequency
of the uniform mode on an in-plane magnetic field H was observed both on
increasing and on decreasing H in the range (2-14) kOe, suggesting the absence
of a metastable collinear perpendicular ground state. Further investigation by
magneto-optical vector magnetometry (MOKE-VM) in an unconventional canted-field
geometry provided evidence for a domain structure where the magnetization is
canted with respect to the perpendicular to the film. Spin wave calculations
confirm the absence of stable collinear configurations.Comment: 6 pages, 3 figures (text, appendix and 1 figure added
Direct imaging and spectroscopy of exoplanets with the ELT/HARMONI high-contrast module
Combining high-contrast imaging with medium-resolution spectroscopy has been shown to significantly boost the direct detection of exoplanets. HARMONI, one of the first-light instruments to be mounted on ESO’s future extremely large telescope (ELT), will be equipped with a single-conjugated adaptive optics system to reach the diffraction limit of the ELT in the H and K bands, a high-contrast module dedicated to exoplanet imaging, and a medium-resolution (up to R = 17 000) optical and near-infrared integral field spectrograph. When combined, these systems will provide unprecedented contrast limits at separations between 50 and 400 mas. This paper is aimed at estimating the capabilities of the HARMONI high-contrast module for the direct detection of young giant exoplanets. We use an end-to-end model of the instrument to simulate high-contrast observations performed with HARMONI, based on realistic observing scenarios and conditions. We then analyze these data with the so-called “molecule mapping” technique combined with a matched-filter approach in order to disentangle companions from the host star and tellurics and to increase the signal-to-noise ratio (S/N) of the planetary signal. We detected planets above 5σ at contrasts up to 16 mag and separations down to 75 mas in several spectral configurations of the instrument. We show that molecule mapping allows for the detection of companions up to 2.5 mag fainter compared to state-of-the-art high-contrast imaging techniques based on angular differential imaging. We also demonstrate that the performance is not strongly affected by the spectral type of the host star and we show that we are able to reach close sensitivities for the best three quartiles of observing conditions at Armazones, which means that HARMONI could be used in near-critical observations during 60 to 70% of telescope time at the ELT. Finally, we simulated planets from population synthesis models to further explore the parameter space that HARMONI and its high-contrast module will open up and compare this to the current high-contrast instrumentation
Review of high-contrast imaging systems for current and future ground- and space-based telescopes I. Coronagraph design methods and optical performance metrics
The Optimal Optical Coronagraph (OOC) Workshop at the Lorentz Center in
September 2017 in Leiden, the Netherlands gathered a diverse group of 25
researchers working on exoplanet instrumentation to stimulate the emergence and
sharing of new ideas. In this first installment of a series of three papers
summarizing the outcomes of the OOC workshop, we present an overview of design
methods and optical performance metrics developed for coronagraph instruments.
The design and optimization of coronagraphs for future telescopes has
progressed rapidly over the past several years in the context of space mission
studies for Exo-C, WFIRST, HabEx, and LUVOIR as well as ground-based
telescopes. Design tools have been developed at several institutions to
optimize a variety of coronagraph mask types. We aim to give a broad overview
of the approaches used, examples of their utility, and provide the optimization
tools to the community. Though it is clear that the basic function of
coronagraphs is to suppress starlight while maintaining light from off-axis
sources, our community lacks a general set of standard performance metrics that
apply to both detecting and characterizing exoplanets. The attendees of the OOC
workshop agreed that it would benefit our community to clearly define
quantities for comparing the performance of coronagraph designs and systems.
Therefore, we also present a set of metrics that may be applied to theoretical
designs, testbeds, and deployed instruments. We show how these quantities may
be used to easily relate the basic properties of the optical instrument to the
detection significance of the given point source in the presence of realistic
noise.Comment: To appear in Proceedings of the SPIE, vol. 1069
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