Thermoelectric Figure of Merit of Strongly Correlated Superlattice Semiconductors

We solved the Anderson Lattice Hamiltonian to get the energy bands of a strongly correlated semiconductor by using slave boson mean field theory. The transport properties were calculated in the relaxation-time approximation,and the thermoelectric figure of merit was obtained for the strongly correlated semiconductor and its superlattice structures. We found that at room temperature $ZT$ can reach nearly 2 for the quantum wire lattice structure.We believe that it is possible to find high values of thermoelectric figure of merit from strongly correlated semiconductor superlattice systems.Comment: 4 pages, 3 figure

A Configurable Smart E-Nose for Spatio-Temporal Olfactory Analysis

This paper describes a novel electronic nose (enose) aimed at applications that require knowing not only the gas composition and concentration, but also its temporal and spatial evolution. This is done by capturing additional information related to the chemical substance such as the timestamp and geo-location of the measurements, as well as other physical magnitudes of the environment like temperature and humidity for correcting and interpreting the data. The device has been conceived following a modular architecture as a set of independent smart modules, which are interconnected and controlled through an I2C interface by a central processing unit. Each smart module can identify itself, store settings for autoconfiguration and perform signal pre-processing of the measured variables. Smart module types include: chemical sensors, communication interfaces, batteries, data storage, GPS, temperature and humidity.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Thermal Jeans fragmentation within 1000 AU in OMC-1S

We present subarcsecond 1.3 mm continuum ALMA observations towards the Orion Molecular Cloud 1 South (OMC-1S) region, down to a spatial resolution of 74 AU, which reveal a total of 31 continuum sources. We also present subarcsecond 7 mm continuum VLA observations of the same region, which allow to further study fragmentation down to a spatial resolution of 40 AU. By applying a Mean Surface Density of Companions method we find a characteristic spatial scale at ~560 AU, and we use this spatial scale to define the boundary of 19 `cores' in OMC-1S as groupings of millimeter sources. We find an additional characteristic spatial scale at ~2900 AU, which is the typical scale of the filaments in OMC-1S, suggesting a two-level fragmentation process. We measured the fragmentation level within each core and find a higher fragmentation towards the southern filament. In addition, the cores of the southern filament are also the densest (within 1100 AU) cores in OMC-1S. This is fully consistent with previous studies of fragmentation at spatial scales one order of magnitude larger, and suggests that fragmentation down to 40 AU seems to be governed by thermal Jeans processes in OMC-1S.Comment: Accepted to Ap

Creating maps of VOC odors in urban areas by cycling with a portable e-nose

This work describes an application for monitoring volatile organic compounds (VOCs) in urban areas, likely coming from residential waste or the public sewage system. The objective is to obtain a spatial and temporal representation of such odors by means of a gas distribution map, from which valuable information such as the location, or the time-intervals of maximum strength of the nuisance odors can be inferred. The necessary data: chemical, temporal and spatial; is provided by a GPS and a specific e-nose accommodating eight metal oxide (MOX) gas sensors, both mounted on a bicycle. The results of a monitoring campaign carried out in a town in southern Spain are presented. The campaign comprises nine measurement runs distributed along three consecutive days, with a total path of more than 90Km. Fig.1 shows an illustrative example of the data collected during this process, and the generated geo-referenced gas distribution maps. As can be appreciated, the chemical, temporal and spatial data are successfully merged to obtain representative information about the presence of VOCs in the urban area. A deeper analysis comprising the study of the areas showing the higher VOCs concentration, as well as the temporal variability among the different days and hours within the day are also provided.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.Proyectos de Excelencia de la Junta de Andalucía: TEP08-4016 y TEP2012-53

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads

Allosteric compounds that stimulate Hsp90 adenosine triphosphatase (ATPase) activity were rationally designed, showing anticancer potencies in the low micromolar to nanomolar range. In parallel, the mode of action of these compounds was clarified and a quantitative model that links the dynamic ligand-protein cross-talk to observed cellular and in vitro activities was developed. The results support the potential of using dynamics-based approaches to develop original mechanism-based cancer therapeutics

Radiomarcaje y estudios de biodistribución de nanopartículas poliméricas como adyuvantes para la vacunación oftálmica frente a la brucelosis

Objetivos: Optimizar el radiomarcaje con 99mTc de nanopartículas de Gantrez® manosiladas y cargadas con el antígeno de Brucella Ovis (Man-NP-HS) y llevar a cabo estudios de biodistribución en ratón tras la administración de las nanopartículas por vía ocular. Metodología: Las Man-NP-HS se obtuvieron por el método de desplazamiento de disolvente. Se purificaron, liofilizaron y caracterizaron. A continuación, se marcaron con 74 MBq de 99mTcO4 - previamente reducido con una disolución ácida de cloruro de estaño, trabajando en ausencia de oxígeno y con un pH final de 4. El rendimiento del marcaje se evaluó mediante TLC. Los estudios de biodistribución se llevaron a cabo en ratones tras la administración oftálmica de la formulación y de un control de 99mTcO4 - libre. Para ello, se sacrificaron los animales a las 2 y a las 24 horas tras la administración ocular y se contaron los órganos en un contador gamma. Resultados: Se obtuvo un rendimiento de marcaje superior al 90%. Los estudios de biodistribución de 99mTc-Man-NP-HS permitieron detectar la actividad concentrada en mucosa nasal y ocular y tracto gastrointestinal tanto a las 2 como a las 24 horas, frente a la biodistribución de 99mTcO4 - libre que permaneció concentrado en la piel alrededor del ojo y en tracto gastrointestinal. Conclusión: Los estudios de biodistribución de 99mTc-Man-NP-HS tras administración oftálmica han permitido demostrar su biodistribución en mucosas y tracto gastrointestinal, característica indispensable como sistema de liberación de antígenos a través de mucosa ocular. Esto, junto con su elevada respuesta inmune, efectiva protección y no virulencia, convierte a estas nanopartículas en una vacuna ideal anti Brucelosis