A detailed analysis of the Gl 486 planetary system

Context. The Gl 486 system consists of a very nearby, relatively bright, weakly active M3.5 V star at just 8 pc with a warm transiting rocky planet of about 1.3 R-circle plus and 3.0 M-circle plus. It is ideal for both transmission and emission spectroscopy and for testing interior models of telluric planets. Aims. To prepare for future studies, we aim to thoroughly characterise the planetary system with new accurate and precise data collected with state-of-the-art photometers from space and spectrometers and interferometers from the ground. Methods. We collected light curves of seven new transits observed with the CHEOPS space mission and new radial velocities obtained with MAROON-X at the 8.1 m Gemini North telescope and CARMENES at the 3.5 m Calar Alto telescope, together with previously published spectroscopic and photometric data from the two spectrographs and TESS. We also performed near-infrared interferometric observations with the CHARA Array and new photometric monitoring with a suite of smaller telescopes (AstroLAB, LCOGT, OSN, TJO). This extraordinary and rich data set was the input for our comprehensive analysis. Results. From interferometry, we measure a limb-darkened disc angular size of the star Gl 486 at theta(LDD) = 0.390 +/- 0.018 mas. Together with a corrected Gaia EDR3 parallax, we obtain a stellar radius R-* = 0.339 +/- 0.015 R-circle plus. We also measure a stellar rotation period at P-rot = 49.9 +/- 5.5 days, an upper limit to its XUV (5-920 A) flux informed by new Hubble/STIS data, and, for the first time, a variety of element abundances (Fe, Mg, Si, V, Sr, Zr, Rb) and C/O ratio. Moreover, we imposed restrictive constraints on the presence of additional components, either stellar or sub-stellar, in the system. With the input stellar parameters and the radial-velocity and transit data, we determine the radius and mass of the planet Gl 486 b at R-p = 1.343(-0.062)(+0.063) R-circle plus and M-p = 3.00(-0.12)(+0.13) M-circle plus, with relative uncertainties of the planet radius and mass of 4.7% and 4.2%, respectively. From the planet parameters and the stellar element abundances, we infer the most probable models of planet internal structure and composition, which are consistent with a relatively small metallic core with respect to the Earth, a deep silicate mantle, and a thin volatile upper layer. With all these ingredients, we outline prospects for Gl 486 b atmospheric studies, especially with forthcoming James Webb Space Telescope (Webb) observations.The David & Lucile Packard FoundationHeising-Simons FoundationGemini ObservatoryUniversity of ChicagoMax Planck SocietyConsejo Superior de Investigaciones Cientificas (CSIC)Spanish GovernmentEuropean Commission FICTS-2011-02 ICTS-2017-07-CAHA-4 CAHA16-CE-3978German Research Foundation (DFG) FOR2544National Science Foundation (NSF) AST-1636624 AST-2034336 2108465 DGE 1746045European Research Council (ERC) 639889National Aeronautics & Space Administration (NASA) XRP NNX16AD43GNational Science Foundation (NSF) AST 1909165Wise Observatory, Tel-Aviv University, Israel TAU2021A-015Agencia Estatal de Investigacion of the Ministerio de Ciencia, Innovacion y Universidades and the ERDF PID2019-109522GB-C5[1:4] PID2019-107061GBC64 PID2019-110689RB-100 PGC2018-095317-B-C21 PGC2018-102108-BI00Centre of Excellence "Severo Ochoa" CEX2019-000920-SCentre of Excellence "Maria de Maeztu" CEX2019-000920-SInstituto de Astrofisica de Andalucia SEV-2017-0709Centro de Astrobiologia MDM2017-0737German Research Foundation (DFG)European Commission FOR2544 (KU 3625/2-1)Germany's Excellence Strategy to the Excellence Cluster ORIGINS EXC-2094 -390783311European Research Council (ERC)European Commission 639889Bulgarian National Science Fund through VIHREN-2021 KP-06-DB/5Schweizerischer Nationalfonds zur Forderung der wissenschaftlichen Forschung/Fonds national suisse de la recherche scientifique PZ00P2_174028United Kingdom Science Technology and Facilities Council 630008203Princeton UniversityUniversidad La Laguna through the Margarita Salas Fellowship from the Spanish Ministerio de UniversidadesEU Next Generation funds UNI/551/2021Generalitat de Catalunya (CERCA programme

City, cholera, and COVID: A reading mediated by religiosity and science

On its way to liberalism and, above all, in relation to the difficulties that characterized this moment, the 19th century was fundamental in the configuration of the societies of Mexican cities and, in particular, of peripheral neighborhoods. This process is discussed in this article from a phenomenological and hermeneutic position and with ethnographic and historiographic tools. It considers the cases of the vice-royal neighborhoods of Analco and La Luz in the baroque city of Puebla. Historical factors are described that shaped its processes during a public health emergency. It is shown that the everyday life of its inhabitants had a dual character, mediated by religiosity and science. Thus, the streets functioned and still do function as the neighborhood center, the symbolic site of this syncretism and the site for neighborhood tactics in the protective search for a sense of identity. Also, the eventual and the permanent are found in the streets, where space becomes where one is and lives, as the symbol of attachment and belonging. The relevance of the text lies in the fact that it offers a privileged testimonial position for understanding what was done and what was understood during a disruptive event like COVID-19 from a social and collective lens. In addition, this text contributes to documenting the origin of new elements that add to existing immaterial heritage

Spectral aerosol radiative forcing and efficiency of the La Palma volcanic plume over the Izaña Observatory

On 19 September 2021, a volcanic eruption began on the island of La Palma (Canary Islands, Spain). The eruption has allowed the assessment of an unprecedented multidisciplinary study on the effects of the volcanic plume. This work presents the estimation of the spectral direct radiative forcing (∆F) and efficiency (∆F E f f) from solar radiation measurements at the Izaña Observatory (IZO) located on the island of Tenerife (∼140 km from the volcano). During the eruption, the IZO was affected by different types of aerosols: volcanic, Saharan mineral dust, and a mixture of volcanic and dust aerosols. Three case studies were identified using ground based (lidar) data, satellite-based (Sentinel5P Tropospheric Monitoring Instrument, TROPOMI) data, reanalysis data (Modern-Era Retrospective Analysis for Research and Applications, version 2, MERRA-2), and backward trajectories (Flexible Trajectories, FLEXTRA), and subsequently characterised in terms of optical and micro-physical properties using ground based sun-photometry measurements. Despite the ∆F of the volcanic aerosols being greater than that of the dust events (associated with the larger aerosol load present), the ∆F E f f was found to be lower. The spectral ∆F E f f values at 440 nm ranged between −1.9 and −2.6 Wm−2nm−1AOD−1 for the mineral dust and mixed volcanic and dust particles, and between −1.6 and −3.3 Wm−2nm−1AOD−1 for the volcanic aerosols, considering solar zenith angles between 30◦ and 70◦, respectively.The authors also acknowledge the support of ACTRIS, Ministerio de Ciencia e Innovación of Spain, through the projects SYNERA: PID2020-118793GA-I00 and RT2018- 097864-B-I00, and Junta de Castilla y León grant N◦. VA227P20

Decolorization and detoxification of synthetic dyes by mexican strains of trametes sp

Laccases have attracted a great deal of interest because of their remarkable ability for the degradation of synthetic dyes present in wastewaters. New laccase producing sources with robust operational and functional properties are being continuously explored. In this work, the potential for the decolorization and detoxification of synthetic dyes was evaluated in two Mexican strains of the genus Trametes. The decolorization capacity of Trametes maxima LE130 and Trametes sp. LA1 was tested in solid and liquid media. The phytotoxicity of the degradation products was determined using Raphanus sativus and Pisum sativum seeds. In solid media, both strains showed a higher decolorization capacity (p ≤ 0.05) than Phanerochaete chrysosporium ATCC 24725, which is known to be very efficient in lignin and dye-degradation. They produced laccase as the main ligninolytic enzyme; T. maxima LE130 secreted a single isoform of 43.9 kDa, while Trametes sp. LA1 produced three isoforms of 67.3, 58.6 and 52.7 kDa, respectively. Trametes sp. LA1 culture fluids were capable of decolorizing and detoxifying chemically diverse dyes (anthraquinonic dye Remazol Brilliant Blue R, azoic Reactive Black 5 and triphenylmethane Crystal Violet) without the addition of redox mediators. Therefore, this could be considered as a new laccase source which could be potentially competitive in the bioremediation of dye-containing wastewaters.Fil: Levin, Laura Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; ArgentinaFil: Hernández Luna, Carlos E.. Universidad Autonoma de Nuevo Leon.; MéxicoFil: Niño Medina, Guillermo. Universidad Autonoma de Nuevo Leon.; MéxicoFil: García Rodríguez, Juan Pablo. Universidad Autonoma de Nuevo Leon.; MéxicoFil: López Sadin, Iosvany. Universidad Autonoma de Nuevo Leon.; MéxicoFil: Méndez Zamora, Gerardo. Universidad Autonoma de Nuevo Leon.; MéxicoFil: Gutiérrez Soto, Guadalupe. Universidad Autonoma de Nuevo Leon.; Méxic

Clinical Utility of microRNAs in Exhaled Breath Condensate as Biomarkers for Lung Cancer.

This study represents a novel proof of concept of the clinical utility of miRNAs from exhaled breath condensate (EBC) as biomarkers of lung cancer (LC). Genome-wide miRNA profiling and machine learning analysis were performed on EBC from 21 healthy volunteers and 21 LC patients. The levels of 12 miRNAs were significantly altered in EBC from LC patients where a specific signature of miR-4507, miR-6777-5p and miR-451a distinguished these patients with high accuracy. Besides, a distinctive miRNA profile between LC adenocarcinoma and squamous cell carcinoma was observed, where a combined panel of miR-4529-3p, miR-8075 and miR-7704 enabling discrimination between them. EBC levels of miR-6777-5p, 6780a-5p and miR-877-5p predicted clinical outcome at 500 days. Two additional miRNA signatures were also associated with other clinical features such as stage and invasion status. Dysregulated EBC miRNAs showed potential target genes related to LC pathogenesis, including CDKN2B, PTEN, TP53, BCL2, KRAS and EGFR. We conclude that EBC miRNAs might allow the identification, stratification and monitorization of LC, which could lead to the development of precision medicine in this and other respiratory diseases

Evaluation of polymeric nanofiltration membranes on metal valorisation from acidic mine waters

Postprint (author's final draft

Cambios en el perfil bioquímico hepático de alpacas positivas a huevos de Fasciola hepática

The aim of this study was to determine changes in the liver biochemical profile in alpacas with presence of F. hepatica eggs. We used serum and feces samples of 35 male alpaca between 2-5 years old, 18 were positives and 17 were negatives in coproparasitologic analysis for F. hepatica eggs. Differences are showed (p<0.05) in the values of ALT, GGT and direct bilirubin between positives y negatives animals. We concluded that there is relationship between presence of F. hepatica eggs and high levels in the liver biochemical profile, maybe due to alterations in the hepatic parenchyma by chronic infection in alpacas.El objetivo del presente estudio fue determinar cambios en el perfil bioquímico hepático en alpacas con presencia de huevos de F. hepatica en heces. Se utilizaron muestras de suero y heces de 35 alpacas machos de entre 2 y 5 años de edad, de los cuales 18 fueron positivos y 17 negativos al examen coproparasitológico (sedimentación) para identificación de huevos de F. hepática. Se observó diferencia significativa (p<0.05) entre los valores de ALT, GGT y bilirrubina directa entre los animales positivos y negativos. Concluimos que la presencia de huevos de Fasciola hepatica guarda relación con la elevación de algunos parámetros del perfil hepática posiblemente por alguna alteración en el parénquima producto de una infección crónica en alpacas

Prevalencia de sarcopenia en adultos mayores de dos hogares geriátricos de Pereira, Colombia: Prevalence of sarcopenia in older adults in two retirement homes in Pereira, Colombia

Introduction: Is a risk factor for morbidity, mortality and disability in older adults, so its management is a priority in geriatrics. The aim of this article is to characterize a population of older adults from two geriatric homes and to establish the prevalence of sarcopenia and the degree of dependence. Methods: Cross-sectional study developed in the city of Pereira-Colombia. A population of 72 adults from 65 to 98 years of age was included, using probability sampling. Sarcopenia was determined by means of the Criteria of the European Consensus on Definition and Diagnosis of Sarcopenia, evaluating grip strength, skeletal muscle mass index, in case of sarcopenia, the severity of sarcopenia together with walking speed, and the degree of dependence according to the Barthel scale.  Results: 57 people participated. A total of 68.4% (n=39) were women. The median age was 83 years. Two percent had no sarcopenia, 9% had suspected sarcopenia, 28% had confirmed sarcopenia and 61% had severe sarcopenia. According to the Barthel scale, 31.5% were independent, 45.6% had mild, 15.8% moderate, 5.3% severe and 1.8% total dependence. Conclusions: The prevalence of sarcopenia in nursing homes in Pereira is higher compared to that reported in the literature. Similarly, being in a private nursing home does not guarantee a better physical condition and/or quality of lifeIntroducción: La sarcopenia es un factor de riesgo para morbilidad, mortalidad y discapacidad en adultos mayores, por lo que su manejo es prioridad en geriatría. El objetivo de este artículo, consiste en caracterizar una población de adultos mayores de dos hogares geriátricos y establecer la prevalencia de sarcopenia y el grado de dependencia. Métodos: Estudio de corte transversal desarrollado en la ciudad de Pereira-Colombia. Se incluyó a una población de 72 adultos desde los 65 hasta los 98 años, usando muestreo probabilístico. Se determinó la sarcopenia por medio de los Criterios del Consenso Europeo sobre Definición y Diagnóstico de Sarcopenia; evaluándose la fuerza de prensión, índice de masa muscular esquelética, en caso de presentarse sarcopenia, la severidad de esta junto a la velocidad de marcha, y el grado de dependencia según la escala de Barthel. Resultados: Participaron finalmente 57 personas. El 68,4% (n=39) eran mujeres. La mediana de la edad fue de 83 años. El 2% no presentó sarcopenia, 9% presentaban sospecha de sarcopenia, 28% tenían sarcopenia confirmada y 61% sarcopenia grave. Según la escala de Barthel, el 31,5% eran independientes, 45,6% tenían dependencia leve, 15,8% moderada, 5,3% severa y 1,8% total. Conclusiones: La prevalencia de sarcopenia en los hogares geriátricos de Pereira es mayor en comparación a la reportada en la literatura. Del mismo modo, encontrarse en un hogar geriátrico privado no garantiza una mejor condición física y/o calidad de vida

Razões para a atividade física no tempo livre e sua relação o cumprimento das recomendações

Los objetivos del estudio fueron: describir los motivos para practicar actividad física en el tiempo libre (AFTL) en adultos de Madrid y analizar su asociación con el sexo y la edad y con la posibilidad de cumplir las recomendaciones de AF. Se realizó un estudio transversal con 1500 personas de Madrid (15-74 años). La AFTL se evaluó con la versión 2 del Global Physical Activity Questionnaire y los motivos de práctica mediante la versión española de la escala Motives for Physical Activity Measure-Revised. Los motivos se ordenaron así: salud (6.19±.87), disfrute (5.67±1.05), competencia (4.84±1.31), social (4.81±1.70) y apariencia (4.63±1.52). Conceder una relevancia alta a los motivos salud y competencia se asoció con mayor probabilidad de cumplir las recomendaciones (OR=1.69 y OR=1.83, respectivamente). La salud es el motivo más importante para la práctica de AFTL en la muestra estudiada. Le siguen: disfrute, competencia, relaciones sociales y apariencia. Las mujeres conceden importancia alta a la salud y a la apariencia, más que los hombres. El protagonismo del motivo salud aumenta con la edad. Para los motivos de competencia, social y apariencia la tendencia es opuesta. La probabilidad de alcanzar las recomendaciones es mayor cuando se concede una importancia alta a la salud o a la competenciaThe aim of the study was to describe the motives for Leisure Time Physical Activity (LTPA) in Madrid adults; analyse their association to gender and age, and with the possibility of meeting the physical activity recommendations. A cross-sectional study from 1500 subjects living in Madrid (age: 15-74 years). LTPA was assessed using Global Physical Activity Questionnaire (version 2), and practice motives using the Spanish version of the Motives for Physical Activity Measure-Revised scale. Motives for LTPA were reported in the following order: fitness (6.19±.87), enjoyment (5.67±1.05), competence (4.84±1.31), social (4.81±1.70) and appearance (4.63±1.52). Conceding a high relevance to the motives of fitness or competence was associated to a higher possibility of meeting the recommendations (OR=1.69 y OR=1.83, respectively). Based in the studied sample, health is the main important motive for LTPA practice. Followed by enjoyment, competence, social relations and appearance. Women concede a higher importance to health and appearance than men. The importance of health motive increase with the age, while the competence, social and appearance motives have the opposite tendency. The possibility of meeting the PA recommendations is higher when a higher importance to health or competence is concededOs objetivos do estudo foram descrever as razões para a prática de atividade física no tempo livre entre adultos em Madrid e analisar sua associação com sexo e idade e a possibilidade de implementar as recomendações do AF. Um estudo cruz com 1500 pessoas em Madrid (15-74 anos) foi realizada. LTPA foi avaliada com a versão 2 da Global Physical Activity Questionnaire e as razões para a prática pela versão em espanhol dos motivos de escala para a atividade física Medida-Revised. As razões são ordenados da seguinte forma: saúde (6.19 ± .87), prazer (5.67 ± 1.05), a concorrência (4.84 ± 1.31), social (4.81 ± 1.70) e aparência (4,63 ± 1,52). Concedesse uma alta relevância a razões de saúde e à concorrência foi associado com cumprir as recomendações (OR = 1.69 e OR = 1.83, respectivamente). A saúde é a prática mais importante da AFL na mostra estudada. Pelar seguintes razões: Prazer, Competição, relações sociais e aparência. As mulheres dão mais importância a saúde e aparência, mais do que os homens. O papel da razão da saúde aumenta com a idade. Por razões de concorrência, social e aparência a tendência é oposta. A probabilidade de alcançar as recomendações é maior quando uma elevada importância foi anexada para a saúde ou a concorrênci

Elucidating historical fisheries’ networks in the Iberian Peninsula using stable isotopes

[EN] Processed fish is known to have been systematically traded in Europe since the Early Middle Ages to meet increasing demand of incipient markets and religious precepts, yet specific details regarding the supply of different fish in Southern Europe is often missing. Here, we address this gap through an integrated approach involving bone metrics and stable isotopic analysis of archaeological European hake (Merluccius merluccius, Merluccidae) from the Iberian Peninsula. The results offer new insights regarding historical fisheries production systems, including the regions exploited and commercial routes, whilst also revealing biological differences between archaeological and present-day hake populations in the North-east Atlantic and the Mediterranean Sea. This research highlights the fruitful result of combining ichthyoarchaeological and historical data for tracking down the origin and development of historical fisheries in south-western Europe and their bearing on modern fisheries.SIThis research was mainly supported by the European Commission through the FISHARC-IF 658022 Marie-Curie-Sklodowska-IF fellowship for Career development. Additional support was received by the Spanish Ministry of Economy and Competitiveness [HAR 2014-55722-P (Ictioarqueologia de la Prehistoria cantábrica: Modelos para la caracterización de las primeras pesquerías europeas), HAR 2017-88325-P (Historical archaeobiology of the European hake (Merluccius merluccius, L.1758) in the NE Atlantic: The Iberian evidence (AD 10th–18th)), and the European Molecular Biology Organization (ASTF 354-2016). The research is also under the framework of the the Leidse Universiteit Fonds-Bakels 2021 fund, the PID-118662GB-100 (FISHCIIS - Fishing Isotopes) project from the Ministry of Science and Innovation, and the Research Group of Cultural Landscapes and Heritage of the University of the Basque Country. We finally want to thank two anonymous reviewers for their helpful suggestions that have improved the quality of this paper. This work contributes to the “María de Maeztu” Programme for Units of Excellence of the Spanish Ministry of Science and Innovation (CEX2019-000940-M)