Comunicação integrada em órgãos públicos: o trabalho da Assessoria de Imprensa na comunicação online e offline

O objetivo principal desse trabalho é identificar quais são os desafios para o assessor de imprensa em órgãos públicos na implantação da Comunicação Integrada e na utilização das mídias online e offline. Por meio de um questionário, que foi respondido por assessores de imprensa (do Legislativo, do Executivo e do Judiciário) que trabalham em órgãos públicos, foram fornecidas informações para identificar as novas atribuições do assessor de imprensa na Comunicação Integrada. O estudo constatou que esta nova dinâmica de trabalho é utilizada nos setores de Comunicação, e que os assessores de imprensa têm um papel importante nas ações e campanhas online e offline que são realizadas para que estas tornem-se mais próximas do cidadão por meio da transparência e da divulgação das atividades governamentais. As assessorias de imprensa utilizam as mídias online e offline dentro do modelo da Comunicação Integrada, e percebeu-se a necessidade que a integração do online com o offline é indispensável para se atingir ao máximo o público-alvo

Parameters, strategies and techniques of game analysis

The development of a game with educational purposes, similar to a game focusing on fun, requires an analysis process, which must evaluate positive and negative points, to support a plan of product improvement. The game A mansão de Quelícera, supported by the CNPq project “Diálogos entre Arte e Design” (Dialogues between Art and Design), was reviewed by a group of researchers from different institutions of higher education in Brazil. Different parts of the game were the subject of evaluation and redesign, as presented in two articles presented in SBGames 2012. In this article, the research explores parameters, strategies and analysis’ techniques of digital games, pointing out existing approaches and the ones organized by researchers of the group, whose action part of the gameplayer interaction. The theoretical foundation for this research considered the parameters of quality for computer games and the parameters defined by the MEC (Ministry of Education-Brazil) to evaluate educational technologies, as well as made use of strategies and techniques for data collection.O desenvolvimento de um jogo com fins educacionais, similarmente a um jogo com foco na diversão, requer um processo de análise, o qual deve avaliar pontos positivos e negativos, para embasar um plano de aperfeiçoamento do produto. O jogo A Mansão de Quelícera, contemplado pelo projeto CNPq “Diálogos entre Arte e Design”, esteve em processo de análise por um grupo de pesquisadores de diferentes instituições de ensino superior brasileiras. Diferentes partes do jogo foram objeto de avaliação e de remodelagem, como apresentado em dois artigos no SBGames 2012. Neste artigo, a pesquisa explora parâmetros, estratégias e técnicas de análise de jogos digitais, pontuando abordagens existentes e as organizadas por pesquisadores do grupo, cuja ação parte da interação jogador-jogo. O embasamento teórico para esta pesquisa considerou os parâmetros de qualidade para jogos de computadores e os parâmetros definidos pelo MEC para avaliar tecnologias educacionais, bem como utilizou-se de estratégias e técnicas para a coleta de dados.info:eu-repo/semantics/publishedVersio

Parameters, strategies and techniques of game analysis

The development of a game with educational purposes, similar to a game focusing on fun, requires an analysis process, which must evaluate positive and negative points, to support a plan of product improvement. The game A mansão de Quelícera, supported by the CNPq project “Diálogos entre Arte e Design” (Dialogues between Art and Design), was reviewed by a group of researchers from different institutions of higher education in Brazil. Different parts of the game were the subject of evaluation and redesign, as presented in two articles presented in SBGames 2012. In this article, the research explores parameters, strategies and analysis’ techniques of digital games, pointing out existing approaches and the ones organized by researchers of the group, whose action part of the gameplayer interaction. The theoretical foundation for this research considered the parameters of quality for computer games and the parameters defined by the MEC (Ministry of Education-Brazil) to evaluate educational technologies, as well as made use of strategies and techniques for data collection.O desenvolvimento de um jogo com fins educacionais, similarmente a um jogo com foco na diversão, requer um processo de análise, o qual deve avaliar pontos positivos e negativos, para embasar um plano de aperfeiçoamento do produto. O jogo A Mansão de Quelícera, contemplado pelo projeto CNPq “Diálogos entre Arte e Design”, esteve em processo de análise por um grupo de pesquisadores de diferentes instituições de ensino superior brasileiras. Diferentes partes do jogo foram objeto de avaliação e de remodelagem, como apresentado em dois artigos no SBGames 2012. Neste artigo, a pesquisa explora parâmetros, estratégias e técnicas de análise de jogos digitais, pontuando abordagens existentes e as organizadas por pesquisadores do grupo, cuja ação parte da interação jogador-jogo. O embasamento teórico para esta pesquisa considerou os parâmetros de qualidade para jogos de computadores e os parâmetros definidos pelo MEC para avaliar tecnologias educacionais, bem como utilizou-se de estratégias e técnicas para a coleta de dados.info:eu-repo/semantics/publishedVersio

Educação física progressista de Ghiraldelli Jr e o proto marxismo na educação física dos anos 1980

A Educação Física, influenciada pela conjuntura dos anos 1980, passou por um processo de renovação com seus autores questionando o histórico conservadorismo da área e assumindo postura de crítica social. O Movimento Renovador da Educação Física tem sido associado à tradição marxista. Entre os fatos históricos marcantes e decisivos para os rumos do campo crítico está o fim da Ditadura Empresarial-Militar, a decadência do socialismo real e a germinação do projeto neoliberal no Brasil. Com a análise de Educação Física Progressista e alguns dos clássicos dos anos 1980 nossa intenção é demostrar que o marxismo sem Marx se fez presente na produção de Ghiraldelli Jr

P53 and Cancer-Associated Sialylated Glycans Are Surrogate Markers of Cancerization of the Bladder Associated with Schistosoma haematobium Infection

BACKGROUND: Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly understood. Bladder cancers in infected populations are generally diagnosed at a late stage since there is a lack of non-invasive diagnostic tools, hence enforcing the need for early carcinogenesis markers. METHODOLOGY/PRINCIPAL FINDINGS: Forty-three formalin-fixed paraffin-embedded bladder biopsies of S. haematobium-infected patients, consisting of bladder tumours, tumour adjacent mucosa and pre-malignant/malignant urothelial lesions, were screened for bladder cancer biomarkers. These included the oncoprotein p53, the tumour proliferation rate (Ki-67>17%), cell-surface cancer-associated glycan sialyl-Tn (sTn) and sialyl-Lewisa/x (sLea/sLex), involved in immune escape and metastasis. Bladder tumours of non-S. haematobium etiology and normal urothelium were used as controls. S. haematobium-associated benign/pre-malignant lesions present alterations in p53 and sLex that were also found in bladder tumors. Similar results were observed in non-S. haematobium associated tumours, irrespectively of their histological nature, denoting some common molecular pathways. In addition, most benign/pre-malignant lesions also expressed sLea. However, proliferative phenotypes were more prevalent in lesions adjacent to bladder tumors while sLea was characteristic of sole benign/pre-malignant lesions, suggesting it may be a biomarker of early carcionogenesis associated with the parasite. A correlation was observed between the frequency of the biomarkers in the tumor and adjacent mucosa, with the exception of Ki-67. Most S. haematobium eggs embedded in the urothelium were also positive for sLea and sLex. Reinforcing the pathologic nature of the studied biomarkers, none was observed in the healthy urothelium. CONCLUSION/SIGNIFICANCE: This preliminary study suggests that p53 and sialylated glycans are surrogate biomarkers of bladder cancerization associated with S. haematobium, highlighting a missing link between infection and cancer development. Eggs of S. haematobium express sLea and sLex antigens in mimicry of human leukocytes glycosylation, which may play a role in the colonization and disease dissemination. These observations may help the early identification of infected patients at a higher risk of developing bladder cancer and guide the future development of non-invasive diagnostic tests

Actividad de gamificación en el aula

Depto. de Optometría y VisiónFac. de Óptica y OptometríaFALSEsubmitte

P53 and cancer-associated sialylated glygans are surrogate markers of cancerization of the bladder associated with \u3ci\u3eSchistosoma haematobium\u3c/i\u3e infection

Background Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly understood. Bladder cancers in infected populations are generally diagnosed at a late stage since there is a lack of non-invasive diagnostic tools, hence enforcing the need for early carcinogenesis markers. Methodology/Principal Findings Forty-three formalin-fixed paraffin-embedded bladder biopsies of S. haematobium-infected patients, consisting of bladder tumours, tumour adjacent mucosa and pre-malignant/malignant urothelial lesions, were screened for bladder cancer biomarkers. These included the oncoprotein p53, the tumour proliferation rate (Ki-67\u3e17%), cell-surface cancer-associated glycan sialyl-Tn (sTn) and sialyl-Lewisa/x (sLea/sLex), involved in immune escape and metastasis. Bladder tumours of non-S. haematobium etiology and normal urothelium were used as controls. S. haematobium-associated benign/pre-malignant lesions present alterations in p53 and sLex that were also found in bladder tumors. Similar results were observed in non-S. haematobium associated tumours, irrespectively of their histological nature, denoting some common molecular pathways. In addition, most benign/pre-malignant lesions also expressed sLea. However, proliferative phenotypes were more prevalent in lesions adjacent to bladder tumors while sLea was characteristic of sole benign/pre-malignant lesions, suggesting it may be a biomarker of early carcionogenesis associated with the parasite. A correlation was observed between the frequency of the biomarkers in the tumor and adjacent mucosa, with the exception of Ki-67. Most S. haematobium eggs embedded in the urothelium were also positive for sLea and sLex. Reinforcing the pathologic nature of the studied biomarkers, none was observed in the healthy urothelium. Conclusion/Significance This preliminary study suggests that p53 and sialylated glycans are surrogate biomarkers of bladder cancerization associated with S. haematobium, highlighting a missing link between infection and cancer development. Eggs of S. haematobium express sLea and sLex antigens in mimicry of human leukocytes glycosylation, which may play a role in the colonization and disease dissemination. These observations may help the early identification of infected patients at a higher risk of developing bladder cancer and guide the future development of non-invasive diagnostic tests

O perfil epidemiológico dos pacientes que frequentaram o setor da hidroterapia na UEAFTO em 2015 / The epidemiological profile of patients who attended the UEAFTO hydrotherapy sector in 2015

Introdução: A hidroterapia é um dos métodos mais antigos de tratamento que utiliza as propriedades físicas da água. Objetivo: Demonstrar o perfil epidemiológico do setor de fisioterapia aquática da Unidade de Ensino e Assistência de Fisioterapia e Terapia Ocupacional. Método: Estudo retrospectivo com análise de prontuários do setor de hidroterapia no ano de 2015. Resultados/Discussão: Prevalência de pacientes do sexo feminino, entre 60 e 70 anos e patologias reumáticas. Conclusão: Observou-se que a maioria dos pacientes atendidos eram idosas do sexo feminino com diagnóstico de doenças reumatológicas, com destaque para a gonartrose. Descritores:

Spanish Cross-Cultural Adaptation and Rasch Analysis of the Convergence Insufficiency Symptom Survey (CISS)

Purpose: To culturally and linguistically adapt the Convergence Insufficiency Symptom Survey (CISS) to Spanish and assess the psychometric performance of the new version through Rasch analysis and classical test theory methods. Methods: The Spanish version of the CISS (CISSVE ) was completed by 449 subjects (9– 30 years old) from the general population. The validity and reliability of CISSVE were assessed through Rasch statistics (precision, targeting, item fit, unidimensionality, and differential item functioning). To test construct validity, we calculated the coefficients of correlation between the CISSVE and the Computer-Vision Symptom Scale (CVSS17) or Warwick–Edinburgh Mental Well-Being Scale (WEMWBS). We determined test–retest reliability in a subset of 229 subjects. We used differential item functioning (DIF) to compare the CISSSVE and the CISS after administering the CISS to 216 English children. Results: After applying exclusion criteria, the responses of 420 participants (mean age, 18.62 years; female, 54.95%) revealed good Rasch model fit, good precision (person separation = 2.33), and suboptimal targeting (–1.37). There was some evidence of multidimensionality, but disattenuated correlations between the Rasch dimension and a possible secondary dimension were high, suggesting they were measuring similar constructs. No item bias according to gender or age was detected. Spearman’s correlation was 0.34 (P < 0.001) for CISSVE –CVSS17 and non-significant for CISSVE –WEMWBS. The limits of agreement for test–retest reliability were 9.67 and –8.71. Rasch analysis results indicated no difference between CISS and CISSVE. Conclusions: According to our results, CISSVE is a valid and reliable tool for measuring the symptoms assessed by CISS in Spanish people 9 to 30 years of age. Translational Relevance: CISSVE can measure convergence insufficiency symptoms in Spanish-speaking subjects