Ulcerated Infantile Hemangioma of the Intergluteal Cleft Treated with Topical Timolol

Dados recentes revelam resultados promissores com a utilização de beta-bloqueante tópico no tratamento dos hemangiomas infantis ulcerados. Os autores descrevem o caso clínico de uma lactente pré-termo de 6 meses de idade com um hemangioma infantil ulcerado do sulco interglúteo tratado com bom resultado clínico com timolol tópico

Vascular Patterns and Morphology in Dermoscopy - Part II. Clinical Practice

A dermatoscopia constitui uma técnica de diagnóstico não-invasiva, in vivo, que permite complementar a observação clínica de lesões cutâneas não-pigmentadas de etiologia diversa. Nos tumores cutâneos não-pigmentados, a dermatoscopia facilita a observação de estruturas vasculares, aumentando a acuidade no seu diagnóstico, distinguindo tumores melanocíticos e não-melanocíticos, benignos e malignos. Na parte II descreve-se a variabilidade da aplicação clínica da dermatoscopia em lesões cutâneas não-pigmentadas tumorais

Vascular Patterns and Morphology in Dermoscopy - Part I. Basic Principles

A dermatoscopia constitui uma técnica de diagnóstico não-invasiva, in vivo, que permite complementar a observação clínica de lesões cutâneas não-pigmentadas de etiologia diversa. Nos tumores cutâneos não-pigmentados, a dermatoscopia facilita a observação de estruturas vasculares, aumentando a acuidade no seu diagnóstico, distinguindo tumores melanocíticos e não-melanocíticos, benignos e malignos. Na parte I deste artigo são discutidos os princípios básicos da avaliação dermatoscópica dos tumores cutâneos não-pigmentados, incluindo a morfologia vascular e os padrões de distribuição dos vasos, assim como de outras pistas adicionais

Improving housing quality as markefing strategy

Prospective housing clients in Portugal face up a marked lack of information on the characteristics of housing products, which most often turn out to be very different of their expectations. This lack of information does not allow them to relate adequately quality and cost. Furthermore, housing products are not adequately differentiated owing to an inefficient approach to the market from the part of different actors in the property sector, which makes difficult the understanding of the true needs and wishes of the client. Nowadays, in a highly competitive housing market, it is increasingly needed to weigh the quality of supply, for housing investment is one of the most important decisions of the Portuguese households. Due to the fact that competition on that market is almost exclusively based on price, there is a need for change in the culture of the housing sector that would promote adequate strategies of marketing and quality. This research project has as the main aim to develop a support tool for the construction enterprises in the housing sector in order to improve the value of their products/services and, to a certain extent, the competitiveness of the sector. The model, which is specifically developed for the town of Bragança, is based on information collected from users in newly occupied housing. It was done through the use of a questionnaire- survey conducted on respondents from fourteen multi-family housing, which were built by four contractors/developers

Ultrasound velocity profile (UVP) measurements in shallow open-channel flows

1st European IAHR Congress, 6-4 May, Edinburgh, ScotlandThis paper is concerned with velocity measurements in shallow water flows by using Ultrasonic Velocity Profile (UVP)probes. The measurements were made in a 10 m long, 0.4 m wide flume whose slope is 0.00117. Diagonal and horizontal positioning of a single probe and the combination of two probes were tested as configurations of the UVP probes. Streamwise and transverse velocities were obtained. A sensitivity analysis was performed to UVP parameters, namely to the distance of the window for each measurement and to the distance between each measuring point. The influence of four different seeding materials was also assessed. Filters for eliminating noise and spikes were applied. For 1D measurements, UVP streamwise velocities were compared with Pitot tube measurements. For 2D measurements, streamwise velocities and turbulent intensities were compared with known laws. The results show the importance of i) setting optimal UVP parameters values, ii) of positioning adequately the UVP probes and iii) using appropriate seeding

Identification of pegmatites zones in Muiane and Naipa (Mozambique) from Sentinel-2 images, using band combinations, band ratios, PCA and supervised classification

Remote sensing has been widely used in Geological Sciences for different applications, such as to identify geological and mineralogical objects and surface alteration changes. This study aimed to analyze the Sentinel-2 potential to detect pegmatite bodies and associated alteration zones in Muiane and Naipa in Mozambique. Different remote sensing techniques were applied to a Sentinel-2 image: RGB combinations, band ratios, principal component analysis (PCA), and supervised image classification algorithms such as the Maximum Likelihood Classifier (MLC) and Support Vector Machine (SVM). MLC was used as a benchmark classifier to evaluate the performance of SVM because MLC is the predominant algorithm employed in remote sensing classification studies. For that, several statistical metrics based on the confusion matrices were computed, namely accuracy, Kappa index, precision, recall, and f-score, among others. This study allows identifying the location of pegmatites by direct identification and segregating between hydrothermally altered zones and non-altered areas through remote sensing data/techniques, supported by field data. The field campaigns allowed for validating the results obtained and verifying the pegmatites identified using Sentinel-2 data that were not previously mapped. Moreover, reflectance spectroscopy studies in the laboratory were conducted on the samples collected in the field campaigns allow to validate the adequacy of the methodology proposed in this study. The results show that the precise identification of pegmatite targets requires a high spatial resolution such as Sentinel-2 images. Thus, with the integration of high spatial and spectral resolution data, a potential level of precision and accuracy can be achieved in the study areas

Tinea Capitis in Adults. A Diagnosis to Consider?

A tinea capitis, uma infecção por fungos dermatófitos do couro cabeludo, é uma patologia rara no adulto, mesmo em áreas geográficas onde a doença é prevalente. Nestes casos está muitas vezes, mas não exclusivamente, associada a imunodepressão e habitualmente surge por exposição ao agente infeccioso em contactantes próximos. São fundamentais uma história clínica e um exame objectivo minuciosos que permitam equacionar a tinha do couro cabeludo como hipótese diagnóstica e proceder à colheita de amostras para exame micológico. Esta metodologia pode evitar a realização de exames complementares exaustivos ou a prescrição de tratamentos inadequados. Os autores descrevem três casos de tinea capitis em mulheres adultas – dois casos de infecção por Microsporum audouinii e um caso por Trichophyton soudanense. É apresentado o registo iconográfico dos casos e é efectuada breve revisão da literatura

Caso para Diagnóstico

Blastic plasmacytoid dendritic cell tumor is a rare, highly aggressive systemic neoplasm for which effective therapies have not yet been established. We describe a 73-year-old man with multiple nodules and patches emerging on the trunk and limbs. Lesional skin biopsy revealed a plasmacytoid dendritic cell tumor with dense dermal infiltrate of tumor cells with blastoid features. No apparent systemic involvement was identified in the initial stage. The patient was treated with prednisone daily, with notorious improvement of the skin lesions, although no complete remission was obtained. During the six-month follow-up period, no disease progression was documented, but fatal systemic progression occurred after that period of time

Semi-Automatization of Support Vector Machines to Map Lithium (Li) Bearing Pegmatites

Machine learning (ML) algorithms have shown great performance in geological remote sensing applications. The study area of this work was the Fregeneda-Almendra region (Spain-Portugal) where the support vector machine (SVM) was employed. Lithium (Li)-pegmatite exploration using satellite data presents some challenges since pegmatites are, by nature, small, narrow bodies. Consequently, the following objectives were defined: (i) train several SVM's on Sentinel-2 images with different parameters to find the optimal model; (ii) assess the impact of imbalanced data; (iii) develop a successful methodological approach to delineate target areas for Li-exploration. Parameter optimization and model evaluation was accomplished by a two-staged grid-search with cross-validation. Several new methodological advances were proposed, including a region of interest (ROI)-based splitting strategy to create the training and test subsets, a semi-automatization of the classification process, and the application of a more innovative and adequate metric score to choose the best model. The proposed methodology obtained good results, identifying known Li-pegmatite occurrences as well as other target areas for Li-exploration. Also, the results showed that the class imbalance had a negative impact on the SVM performance since known Li-pegmatite occurrences were not identified. The potentials and limitations of the methodology proposed are highlighted and its applicability to other case studies is discussed

Cutaneous Sarcoma. From Diagnosis to Treatment

O diagnóstico dos sarcomas cutâneos é desafiante, devido à complexidade e heterogeneidade deste grupo de lesões, cuja apresentação nos tecidos superficiais (pele e tecido celular subcutâneo) impõe diagnóstico diferencial obrigatório com tumores benignos e processos inflamatórios. Apesar de serem tumores pouco frequentes alguns tipos assumem grande importância por serem localmente invasivos, com elevada morbi-mortalidade associada, taxas de recidiva local e metastização significativas. Os autores apresentam cinco casos clínico-patológicos de sarcomas cutâneos – sarcoma de Kaposi, dermatofibrossarcoma protuberans, fibroxantoma atípico, leiomiossarcoma e angiossarcoma – e fazem uma breve revisão da literatura sobre os tipos de sarcoma cutâneo com maior interesse na Dermatologia, salientando os aspectos fisiopatológicos, clínicos, histopatológicos e terapêuticos particulares