1,441 research outputs found

    A Synthesis of Web Services

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    The implications of autonomous commu- nication have been far-reaching and pervasive. In this position paper, we confirm the improvement of voice-over-IP. In this work we use distributed archetypes to demonstrate that link-level acknowledgements and Lamport clocks are usually incompatible

    The role of oxidative stress in the Rotenone model Lymnaea stagnalis

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    Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, characterized by progressive depletion of dopamine (DA). Rotenone, a common pesticide, can induce PD like symptoms in animal models. The goal of this thesis is to quantify the levels and effects of reactive oxygen species (ROS) in brain tissue of the common neurobiological gastropod model, Lymnaea stagnalis, after treatment with Rotenone. The results show that rotenone causes a behavioral deficit and increases ROS production, especially superoxide. Furthermore, glutathione was depleted and protein carbonyl formation increased. These results are consistent with findings in human PD and the high levels of ROS we find in the Lymnaea model suggest that it is a useful avenue to explore the possible causative role of oxidative stress in dopaminergic neurodegeneration

    The Soul of Man Under Capitalism

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    This paper examines the consciousness of three literary characters, divided by space and time, from mid nineteenth century Russia, mid twentieth century Italy, to late twentieth century American society. This paper exposes literature’s rendition of modern man’s varying consciousness as shaped by the changing social conditions around him. This paper recognizes these varying social conditions as different stages in capitalism’s development. Capitalism has a history; the literature this paper examines discloses its negative impact on the consciousness of its characters. In analyzing Notes from the Underground, Contempt, and American Psycho, three novels separated by geography and spanning a timeframe of 127 years, this paper examines each protagonist existing in a state of existential angst proportionate to the stage of capitalism his respective epoch experiences, and respective of his social status. A Marxist framework is used to analyze this literature which reveals modern man’s precarious condition has exacerbated alongside capitalism’s development

    Effects of noise on hysteresis and resonance width in graphene and nanotubes resonators

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    We investigate the role that noise plays in the hysteretic dynamics of a suspended nanotube or a graphene sheet subject to an oscillating force. We find that not only the size but also the position of the hysteresis region in these systems can be controlled by noise. We also find that nano-resonators act as noise rectifiers: by increasing the noise in the setup, the resonance width of the characteristic peak in these systems is reduced and, as a result, the quality factor is increased.Comment: 15 pages, 6 figures. Sent to PRB (in revision

    ThYme: a database for thioester-active enzymes

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    The ThYme (Thioester-active enzYme; http://www.enzyme.cbirc.iastate.edu) database has been constructed to bring together amino acid sequences and 3D (tertiary) structures of all the enzymes constituting the fatty acid synthesis and polyketide synthesis cycles. These enzymes are active on thioester-containing substrates, specifically those that are parts of the acyl-CoA synthase, acyl-CoA carboxylase, acyl transferase, ketoacyl synthase, ketoacyl reductase, hydroxyacyl dehydratase, enoyl reductase and thioesterase enzyme groups. These groups have been classified into families, members of which are similar in sequences, tertiary structures and catalytic mechanisms, implying common protein ancestry. ThYme is continually updated as sequences and tertiary structures become available

    Polystyrene perturbs the structure, dynamics, and mechanical properties of DPPC membranes: An experimental and computational study

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    Synthetic plastic oligomers can interact with the cells of living organisms by different ways. They can be intentionally administered to the human body as part of nanosized biomedical devices. They can be inhaled by exposed workers, during the production of multicomponent, polymer-based nanocomposites. They can leak out of food packaging. Most importantly, they can result from the degradation of plastic waste, and enter the food chain. A physicochemical characterization of the effects of synthetic polymers on the structure and dynamics of cell components is still lacking. Here, we combine a wide spectrum of experimental techniques (calorimetry, x-ray, and neutron scattering) with atomistic Molecular Dynamics simulations to study the interactions between short chains of polystyrene (25 monomers) and model lipid membranes (DPPC, in both gel and fluid phase). We find that doping doses of polystyrene oligomers alter the thermal properties of DPPC, stabilizing the fluid lipid phase. They perturb the membrane structure and dynamics, in a concentration-dependent fashion. Eventually, they modify the mechanical properties of DPPC, reducing its bending modulus in the fluid phase. Our results call for a systematic, interdisciplinary assessment of the mechanisms of interaction of synthetic, everyday use polymers with cell membranes

    Luna Farming Legacy: A Porción of Edinburg

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    Descendants of Spanish Colonial settlers have been practicing subsistence farming along the Rio Grande for over 250 years. As that same river became the international boundary between the US and Mexico in 1848, landownership and the landscape began to change. As issues in Mexico such as the Mexican Revolution pushed families over the river into the Rio Grande Valley of Texas, many folks established themselves as farmers alongside the new arrivals from the American Midwest in the early 1900s. The guarantee of successful year-round farming was a prominent theme and the Lunas were willing and able to embark on that challenge. As their life in the US began with some time in Los Ebanos, the family eventually found themselves purchasing land and farming in Edinburg. Today Luna family members are still farming in a section of northwest Edinburg fondly referred to as Lunaville by fellow farmers.https://scholarworks.utrgv.edu/chapspublications/1000/thumbnail.jp
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