5,219 research outputs found

    Giulia Poggi y Maria Grazia Profeti, eds., Norme per lo spettacolo. Norme per lo spettatore. Teoria e prassi del teatro intorno all’«Arte Nuevo»

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    Review of Giulia Poggi y Maria Grazia Profeti, eds., Norme per lo spettacolo. Norme per lo spettatore. Teoria e prassi del teatro intorno all’«Arte Nuevo», Alinea Editrice, Florencia, 2011, 546 pp. ISBN: 978-88-6055-586-1.Reseña de Giulia Poggi y Maria Grazia Profeti, eds., Norme per lo spettacolo. Norme per lo spettatore. Teoria e prassi del teatro intorno all’«Arte Nuevo», Alinea Editrice, Florencia, 2011, 546 pp. ISBN: 978-88-6055-586-1

    History of the World Allergy Organization

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    La recepción y la difusión del De imitatione Christi en la España del Siglo de Oro

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    The aim of this paper is to show insight into the Golden Age Spain a devotional work composed by the middle of the fifteenth century, the Imitatio Christi, which has been attributed to the Dutch Augustinian monk Thomas a Kempis. Being the most widespread work after the Bible in the Christian tradition, struck by the paucity of studies on diffusion and influence in Golden Age Spain. The present contribution, demonstrating that this work was widely disseminated Spain, by the large number of editions and translations, intended to open the field for future research in the literary field. We insist particularly in the case of Diego de Estella, whose work is postulated that the influence of the Imitatio Christi is so obvious that the model becomes transparent.El objetivo del presente trabajo es el de mostrar la penetración en la España del Siglo de Oro de una obra devocional compuesta hacia la mitad del siglo XV, la Imitatio Christi, que ha sido atribuida al monje agustino holandés Thomas a Kempis. Al tratarse de la obra de mayor difusión después de la Biblia en la tradición cristiana, llama la atención la escasez de estudios sobre su difusión e influencia en la España del Siglo de Oro. La presente contribución, al demostrar que esta obra tuvo amplia difusión en España, por la gran cantidad de ediciones y de traducciones, pretende abrir el campo a futuras pesquisas en el campo literario. Insistimos en particular en el caso de Diego de Estella, en cuya obra se postula que la influencia de la Imitatio Christi es tan evidente que el modelo se hace transparente

    Inpatient and outpatient loop electrosurgery excision procedure for cervical intraepithelial neoplasia: a retrospective analysis

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    Purpose: To determine whether the outpatient loop electrosurgical excision procedure (LEEP) conization (out-LEEP) is as effective and safe as inpatient LEEP conization (in-LEEP) with regard to the complete removal of cervical dysplasia, recurrence-free survival and post-operative morbidity. Methods: 233 patients were included in this retrospective cohort study from January 2002 to December 2007. 181 had outpatient treatment and 52 inpatient treatment. We used Mann-Whitney U test, two-sided Fisher's exact test, Chi-square test, log rank test and Kaplan-Meier curve. Results: Incomplete excision was found in 16/52 (30.8%) cases in the inpatient group and 46/181 (25.4%) in the outpatient group (P=0.48). Six patients had post-operative complications: two cases of secondary haemorrhage in each group (in-LEEP 3.8%, out-LEEP 1.1%, P=0.22) and two cases of cervical stenosis amongst inpatients (3.8%, P=0.049). Alteration of specimen by thermal artifact were reported in 4/52 (7.7%) of in-LEEP cones and 10/181 (5.5%) of out-LEEP cones (P=0.52). Measurements of cones in both groups were comparable with a mean depth of 9.35mm (±5.5mm) and 8.4mm (±3.4mm), respectively. Conclusion: Our results suggest that efficacy and safety of ambulatory LEEP conization is comparable as in inpatient procedur

    Barriers to Asthma Treatment in the United States: Results From the Global Asthma Physician and Patient Survey

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    BACKGROUND: The Global Asthma Physician and Patient (GAPP) survey evaluated the perceptions of both physicians and patients on the management of asthma. Here we present the results from the United States (US) subpopulation of the GAPP survey. METHODS: The GAPP Survey was a large, global study (physicians, n = 1733; patients, n = 1726; interviews, n = 3459). In the US, 208 adults (aged ≥ 18 years) with asthma and 224 physicians were recruited. Respondents were questioned using self-administered online interviews with close-ended questionnaires. RESULTS: Physician and patient responses were found to differ in regard to perception of time spent on asthma education, awareness of disease symptoms and their severity, asthma medication side effects, and adherence to treatment and the consequence of nonadherence. Comparison of the US findings with the global GAPP survey results suggest the US physician-patient partnership compared reasonably well with the other countries in the survey. Both patients and physicians cited a need for new asthma medication. CONCLUSIONS: Similar to the global GAPP survey, the US-specific findings indicate that in general there is a lack of asthma control, poor adherence to therapy, and room for improvement in patient-physician communication and partnership in treating asthma

    The CUORE Cryostat: A 1-Ton Scale Setup for Bolometric Detectors

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    The cryogenic underground observatory for rare events (CUORE) is a 1-ton scale bolometric experiment whose detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. This will be the largest bolometric mass ever operated. The experiment will work at a temperature around or below 10 mK. CUORE cryostat consists of a cryogen-free system based on pulse tubes and a custom high power dilution refrigerator, designed to match these specifications. The cryostat has been commissioned in 2014 at the Gran Sasso National Laboratories and reached a record temperature of 6 mK on a cubic meter scale. In this paper, we present results of CUORE commissioning runs. Details on the thermal characteristics and cryogenic performances of the system will be also given.Comment: 7 pages, 2 figures, LTD16 conference proceedin

    Allergenius, an expert system for the interpretation of allergen microarray results

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    BACKGROUND: An in vitro procedure based on a microarray containing many different allergen components has recently been introduced for use in allergy diagnosis. Recombinant and highly purified allergens belonging to different allergenic sources (inhalants, food, latex and hymenoptera) are present in the array. These components can either be genuine or cross-reactive, resistant or susceptible to heat and low pH, and innocuous or potentially dangerous. A large number of complex and heterogeneous relationships among these components has emerged, such that sometimes these interactions cannot be effectively managed by the allergist. In the 1960s, specialized languages and environments were developed to support the replacement of human experts with dedicated decision-making information systems. Currently, expert systems (ES) are advanced informatics tools that are widely used in medicine, engineering, finance and trading. METHODS: We developed an ES, named Allergenius ®, to support the interpretation of allergy tests based on microarray technology (ImmunoCAP ISAC ®). The ES was implemented using Flex, a LPA Win-Prolog shell. Rules representing the knowledge base (KB) were derived from the literature and specialized databases. The input data included the patient’s ID and disease(s), the results of either a skin prick test or specific IgE assays and ISAC results. The output was a medical report. RESULTS: The ES was first validated using artificial and real life cases and passed all in silico validations. Then, the opinions of allergists with experience in molecular diagnostics were compared with the ES reports. The Allergenius reports included all of the allergists’ opinions and considerations, as well as any additional information. CONCLUSIONS: Allergenius is a trustable ES dedicated to molecular tests for allergy. In the present version, it provides a powerful method to understand ISAC results and to obtain a comprehensive interpretation of the patient’s IgE profiling

    A detector module with highly efficient surface-alpha event rejection operated in CRESST-II Phase 2

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    The cryogenic dark matter experiment CRESST-II aims at the direct detection of WIMPs via elastic scattering off nuclei in scintillating CaWO4_4 crystals. We present a new, highly improved, detector design installed in the current run of CRESST-II Phase 2 with an efficient active rejection of surface-alpha backgrounds. Using CaWO4_4 sticks instead of metal clamps to hold the target crystal, a detector housing with fully-scintillating inner surface could be realized. The presented detector (TUM40) provides an excellent threshold of 0.60{\sim}\,0.60\,keV and a resolution of σ0.090\sigma\,{\approx}\,0.090 keV (at 2.60\,keV). With significantly reduced background levels, TUM40 sets stringent limits on the spin-independent WIMP-nucleon scattering cross section and probes a new region of parameter space for WIMP masses below 3\,GeV/c2^2. In this paper, we discuss the novel detector design and the surface-alpha event rejection in detail.Comment: 9 pages, 6 figure
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