La influencia de familiness en la estrategia de internacionalización empresarial: una aplicación al sector oleícola

[ES] La estrategia de internacionalización empresarial es relevante para las empresas familiares, con unas peculiaridades específicas respecto a otro tipo de empresas, ya que quieren preservar su continuidad con los relevos generacionales. Ahora bien, la literatura ha eliminado tradicionalmente los factores familiares de los modelos estratégicos de las empresas familiares y han sido analizadas siguiendo modelos tradicionales, lo que ha conducido a resultados divergentes sobre su desempeño. Por ello, se ha considerado el solapamiento de los sistemas familia, empresa e individuos para llegar al concepto de familiness, a cuya composición y medición se aproxima este trabajo desde la perspectiva de Capital Social y Sistemas Abiertos, cubriendo la laguna existente en la investigación sobre su composición. Igualmente, se ha analizado la influencia que diferentes niveles de familiness tienen sobre la estrategia de internacionalización empresarial, en concreto, sobre las razones de la empresa para internacionalizarse y en su nivel de compromiso internacional[EN]The internationalization strategy assumes great importance in family businesses, with a set of specific peculiarities that differ from other companies, as they strive to preserve their continuity once they are handed over the next family generation. Nevertheless, the literature has traditionally removed family factors from the development of strategic models of family firms, which instead have been subjected to traditional models that have led to divergent results about their performance. Therefore, it has been considered the overlapping of the systems: family, business and individuals to achieve the concept of familiness. Bridging the research gap in relation to the composition of familiness, this piece of research gives a proposal for assessing its composition and measurement from the Social Capital and Open Systems perspectives. Thus, it has been analyzed the influence of different levels of familiness over the internationalization strategy, specifically, over the business’ reasons to internationalize and over its international commitment.Tesis Univ. Jaén. Departamento de Organización de Empresas, Marketing y Sociología. Leída el 5 de febrero de 201

Intangible assets in the internationalization of Spanish wineries: directive and compared perception between family and non family businesses

Objeto: Determinar cuál es la dotación de recursos intangibles que presentan las empresas del sector vitivinícola español, como fuente de ventaja competitiva en el desarrollo de su estrategia internacional. Estudio exploratorio del impacto que los diferentes recursos intangibles de las bodegas españolas tienen sobre el grado de desarrollo de su estrategia internacional: diferencias en función del carácter familiar o no de las mismas. Diseño/metodología/enfoque: Estudio empírico cuantitativo de carácter básicamente descriptivo a partir del análisis de la información recogida en cuestionarios realizados a directivos de bodegas, familiares y no familiares españolas, representativas del sector en el contexto nacional. Aportaciones y resultados: La dotación de los recursos intangibles que presentan las empresas del sector vitivinícola español, como fuente de la ventaja competitiva en su expansión internacional, varía en relación al tipo de recursos analizados (tecnológicos, humanos, organizativos y relacionales) y, en algunos aspectos, en relación al carácter familiar o no de la empresa. Limitaciones: El hecho de haber concentrado todo el estudio en un único sector económico. Un estudio similar en otros sectores industriales podría ofrecer resultados distintos a los obtenidos en este trabajo. Implicaciones prácticas: Se señalan los principales retos a alcanzar por las empresas vitivinícolas españolas, en relación a su dotación de recursos intangibles, para reforzar y fortalecer su posición competitiva en el mercado internacional. Implicaciones sociales: Este estudio señala cómo podrían distintos organismos e instituciones, relacionados con el sector, de carácter público o privado, ayudar a las empresas a alcanzar los retos que se plantean. De igual manera orienta sobre cuáles y en qué medida han de ser aplicadas las políticas sobre recursos intangibles en este sector. Valor añadido: Pese a existir numerosos datos e información relacionada con el comercio exterior del sector vitivinícola español, ningún estudio anterior se ha centrado en el análisis de los recursos intangibles de estas compañías como fuente de la ventaja competitiva en el desarrollo de la estrategia internacional, ni tampoco se había diferenciado, previamente, entre el carácter familiar o no de las empresas que conforman el sector. Se trata de un primer trabajo que sienta las bases sobre la efectiva dotación de las bodegas familiares españolas.Purpose: To determine which of the intangible resources possessed by companies from the Spanish viticultural sector can serve as a source of competitive advantage in the development of their international strategies. Exploratory study of the impact of the different intangible resources possessed by Spanish wineries on the development of their international strategies: differences depending on the family-owned or non family-owned character of the viticultural companies in question. Design/methodology/approach: Empirical quantitative study of descriptive nature basically using the analysis of information gathered from surveys carried out with managers in Spanish wineries, family and non-family, representative of the sector in the national context. Findings: Companies from the Spanish viticultural sector show an intangible resource endowment, as a source of competitive advantage in the development of their international strategies. This endowment varies depending on the resources analyzed (technological, human, organizational and relational resources) and, in some aspects, does vary depending whether the firm is family-owned or not. Research limitations: We have focused our study in only one economic sector completely. The same analysis or study in other industrial sectors would provide different results from those achieved in this study. Practical implications: The main challenges facing Spanish wineries in achieving success are emphasized taking into consideration their intangible resource endowment, in order to reinforce their competitive position in international markets. Social implications: This study points out the way that different public and private organizations and institutions of the viticultural sector could help wineries to overcome the challenges that have been set out in this study. Just as it directs which different policies and how they should be applied to the intangible resources in the viticultural sector. Originality/value: Although there is numerous data and information about the International trade of the Spanish viticultural sector, no previous study has focused on the analysis of these companies’ intangible resources as a source of competitive advantage in the development of their international strategies. Furthermore, none of these previous studies have taken into account whether the winery is family-owned or not. It is a first piece of work that leads the foundations about the effective resource endowment of Spanish family wineries.Peer Reviewe

Abordant la crisi de les cures : polítiques, treballs i experiències locals

Bibliografi

Differences in clinical features and mortality in very old unvaccinated patients (≥ 80 years) hospitalized with COVID-19 during the first and successive waves from the multicenter SEMI-COVID-19 Registry (Spain)

Background: Old age is one of the most important risk factors for severe COVID-19. Few studies have analyzed changes in the clinical characteristics and prognosis of COVID-19 among older adults before the availability of vaccines. This work analyzes differences in clinical features and mortality in unvaccinated very old adults during the first and successive COVID-19 waves in Spain. Methods This nationwide, multicenter, retrospective cohort study analyzes unvaccinated patients >= 80 years hospitalized for COVID-19 in 150 Spanish hospitals (SEMI-COVID-19 Registry). Patients were classified according to whether they were admitted in the first wave (March 1-June 30, 2020) or successive waves (July 1-December 31, 2020). The endpoint was all-cause in-hospital mortality, expressed as the case fatality rate (CFR). Results Of the 21,461 patients hospitalized with COVID-19, 5,953 (27.7%) were >= 80 years (mean age [IQR]: 85.6 [82.3-89.2] years). Of them, 4,545 (76.3%) were admitted during the first wave and 1,408 (23.7%) during successive waves. Patients hospitalized in successive waves were older, had a greater Charlson Comorbidity Index and dependency, less cough and fever, and met fewer severity criteria at admission (qSOFA index, PO2/FiO2 ratio, inflammatory parameters). Significant differences were observed in treatments used in the first (greater use of antimalarials, lopinavir, and macrolides) and successive waves (greater use of corticosteroids, tocilizumab and remdesivir). In-hospital complications, especially acute respiratory distress syndrome and pneumonia, were less frequent in patients hospitalized in successive waves, except for heart failure. The CFR was significantly higher in the first wave (44.1% vs. 33.3%; -10.8%; p = 95 years (54.4% vs. 38.5%; -15.9%; p < 0.001). After adjustments to the model, the probability of death was 33% lower in successive waves (OR: 0.67; 95% CI: 0.57-0.79). Conclusions Mortality declined significantly between the first and successive waves in very old unvaccinated patients hospitalized with COVID-19 in Spain. This decline could be explained by a greater availability of hospital resources and more effective treatments as the pandemic progressed, although other factors such as changes in SARS-CoV-2 virulence cannot be ruled out

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Global Retinoblastoma Presentation and Analysis by National Income Level.

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs

The reference site collaborative network of the european innovation partnership on active and healthy ageing

Seventy four Reference Sites of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) have been recognised by the European Commission in 2016 for their commitment to excellence in investing and scaling up innovative solutions for active and healthy ageing. The Reference Site Collaborative Network (RSCN) brings together the EIP on AHA Reference Sites awarded by the European Commission, and Candidate Reference Sites into a single forum. The overarching goals are to promote cooperation, share and transfer good practice and solutions in the development and scaling up of health and care strategies, policies and service delivery models, while at the same time supporting the action groups in their work. The RSCN aspires to be recognized by the EU Commission as the principal forum and authority representing all EIP on AHA Reference Sites. The RSCN will contribute to achieve the goals of the EIP on AHA by improving health and care outcomes for citizens across Europe, and the development of sustainable economic growth and the creation of jobs

The global retinoblastoma outcome study : a prospective, cluster-based analysis of 4064 patients from 149 countries

DATA SHARING : The study data will become available online once all analyses are complete.BACKGROUND : Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. METHODS : We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1, 2017, and Dec 31, 2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. FINDINGS : The cohort included 4064 children from 149 countries. The median age at diagnosis was 23·2 months (IQR 11·0–36·5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0·8%) of 636 children from high-income countries, 55 (5·4%) of 1027 children from upper-middle-income countries, 342 (19·7%) of 1738 children from lower-middle-income countries, and 196 (42·9%) of 457 children from low-income countries. Enucleation surgery was available for all children and intravenous chemotherapy was available for 4014 (98·8%) of 4064 children. The 3-year survival rate was 99·5% (95% CI 98·8–100·0) for children from high-income countries, 91·2% (89·5–93·0) for children from upper-middle-income countries, 80·3% (78·3–82·3) for children from lower-middle-income countries, and 57·3% (52·1-63·0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16·67; 95% CI 4·76–50·00), cT4 advanced tumour compared to cT1 (8·98; 4·44–18·18), and older age at diagnosis in children up to 3 years (1·38 per year; 1·23–1·56). For children aged 3–7 years, the mortality risk decreased slightly (p=0·0104 for the change in slope). INTERPRETATION : This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes.The Queen Elizabeth Diamond Jubilee Trust and the Wellcome Trust.https://www.thelancet.com/journals/langlo/homeam2023Paediatrics and Child Healt

Intangibles en la internacionalización de las bodegas españolas: Percepción directiva y comparada entre empresas familiares y no familiares

<p><strong>Objeto:</strong> Determinar cu&aacute;l es la dotaci&oacute;n de recursos intangibles que presentan las empresas del sector vitivin&iacute;cola espa&ntilde;ol, como fuente de ventaja competitiva en el desarrollo de su estrategia internacional. Estudio exploratorio del impacto que los diferentes recursos intangibles de las bodegas espa&ntilde;olas tienen sobre el grado de desarrollo de su estrategia internacional: diferencias en funci&oacute;n del car&aacute;cter familiar o no de las mismas.</p><p><strong>Dise&ntilde;o/metodolog&iacute;a/enfoque: </strong>Estudio emp&iacute;rico cuantitativo de car&aacute;cter b&aacute;sicamente descriptivo a partir del an&aacute;lisis de la informaci&oacute;n recogida en cuestionarios realizados a directivos de bodegas, familiares y no familiares espa&ntilde;olas, representativas del sector en el contexto nacional.</p><p><strong>Aportaciones y resultados: </strong>La dotaci&oacute;n de los recursos intangibles que presentan las empresas del sector vitivin&iacute;cola espa&ntilde;ol, como fuente de la ventaja competitiva en su expansi&oacute;n internacional, var&iacute;a en relaci&oacute;n al tipo de recursos analizados (tecnol&oacute;gicos, humanos, organizativos y relacionales) y, en algunos aspectos, en relaci&oacute;n al car&aacute;cter familiar o no de la empresa.</p><p><strong>Limitaciones: </strong>El hecho de haber concentrado todo el estudio en un &uacute;nico sector econ&oacute;mico. Un estudio similar en otros sectores industriales podr&iacute;a ofrecer resultados distintos a los obtenidos en este trabajo.</p><p><strong> Implicaciones pr&aacute;cticas:</strong> Se se&ntilde;alan los principales retos a alcanzar por las empresas vitivin&iacute;colas espa&ntilde;olas, en relaci&oacute;n a su dotaci&oacute;n de recursos intangibles, para reforzar y fortalecer su posici&oacute;n competitiva en el mercado internacional.</p><p><strong> Implicaciones sociales:</strong> Este estudio se&ntilde;ala c&oacute;mo podr&iacute;an distintos organismos e instituciones, relacionados con el sector, de car&aacute;cter p&uacute;blico o privado, ayudar a las empresas a alcanzar los retos que se plantean. De igual manera orienta sobre cu&aacute;les y en qu&eacute; medida han de ser aplicadas las pol&iacute;ticas sobre recursos intangibles en este sector.</p><p><strong>Valor a&ntilde;adido:</strong> Pese a existir numerosos datos e informaci&oacute;n relacionada con el comercio exterior del sector vitivin&iacute;cola espa&ntilde;ol, ning&uacute;n estudio anterior se ha centrado en el an&aacute;lisis de los recursos intangibles de estas compa&ntilde;&iacute;as como fuente de la ventaja competitiva en el desarrollo de la estrategia internacional, ni tampoco se hab&iacute;a diferenciado, previamente, entre el car&aacute;cter familiar o no de las empresas que conforman el sector. Se trata de un primer trabajo que sienta las bases sobre la efectiva dotaci&oacute;n de las bodegas familiares espa&ntilde;olas.</p