Sistema para el seguimiento de la posición tridimensional de manos

La interacción entre humanos y computadoras se encuentra en constante evolución hacia la reducción del hardware y la naturalización del uso de los dispositivos. Los métodos de procesamiento de imagen permiten delegar el trabajo a las computadoras aprovechando su enorme capacidad. La mano humana es el objeto de interés de este trabajo donde se propone una solución que permita ubicar los dedos del usuario en tres dimensiones por medio de cámaras web tradicionales, minimizando el hardware y desarrollada en C/C++. El método propuesto combina el uso de envolventes convexas para ubicar los dedos en 2 dimensiones, con la generación de mapas de disparidad por medio de estereoscopía para lograr la tridimensionalidad. Los resultados preliminares demostraron la capacidad de realizar el proceso en tiempo real, con la precisión adecuada y funcionando correctamente aún bajo condiciones desfavorables.Trabajos de cátedra.Sociedad Argentina de Informática e Investigación Operativa (SADIO

Changes in vegetation seasonality and livestock stocking rate in La Pampa Province (Argentina)

Crop production is traversing expansion and intensification processes all over the planet and in consequence the large scale cattle production is being displaced to marginal lands with lower stocking capacity. The objective of this work was to assess the seasonality of vegetation in La Pampa province located in a semiarid region in Argentina and to explore if the variations in seasonality are related to the stocking rate. The hypothesis is the changes in stocking rate of rangelands and its grazing pressure alter the proportion of different vegetation functional groups and so the vegetation seasonality. It is predicted that overgrazing of seasonal grasses will alter the proportion of woody species having consequences over spectral indices. It was analyzed satellite data, particularly the MODIS Enhanced Vegetation Index (EVI) and related it to stocking rate records from SENASA. This work evidences the relationship between the stocking rate and the spectral index EVI, indicator of the primary productivity of vegetation, at departmental scale in the natural areas of Monte and Espinal of La Pampa. Results indicate that in western region (Monte) there was an increment in the stocking rate at department level and a decrease in vegetation seasonality. It is posed that the higher grazing pressure led to the overgrazing of the most palatable herbaceous species, increasing the shrub proportion in landscape.Crop production is traversing expansion and intensification processes all over the planet and in consequence the large scale cattle production is being displaced to marginal lands with lower stocking capacity. The objective of this work was to assess the seasonality of vegetation in La Pampa province located in a semiarid region in Argentina and to explore if the variations in seasonality are related to the stocking rate. The hypothesis is the changes in stocking rate of rangelands and its grazing pressure alter the proportion of different vegetation functional groups and so the vegetation seasonality. It is predicted that overgrazing of seasonal grasses will alter the proportion of woody species having consequences over spectral indices. It was analyzed satellite data, particularly the MODIS Enhanced Vegetation Index (EVI) and related it to stocking rate records from SENASA. This work evidences the relationship between the stocking rate and the spectral index EVI, indicator of the primary productivity of vegetation, at departmental scale in the natural areas of Monte and Espinal of La Pampa. Results indicate that in western region (Monte) there was an increment in the stocking rate at department level and a decrease in vegetation seasonality. It is posed that the higher grazing pressure led to the overgrazing of the most palatable herbaceous species, increasing the shrub proportion in landscape

Cambios en la estacionalidad de la vegetación y la carga animal en la provincia de La Pampa (Argentina)

Crop production is traversing expansion and intensification processes all over the planet and in consequence the large scale cattle production is being displaced to marginal lands with lower stocking capacity. The objective of this work was to assess the seasonality of vegetation in La Pampa province located in a semiarid region in Argentina and to explore if the variations in seasonality are related to the stocking rate. The hypothesis is the changes in stocking rate of rangelands and its grazing pressure alter the proportion of different vegetation functional groups and so the vegetation seasonality. It is predicted that overgrazing of seasonal grasses will alter the proportion of woody species having consequences over spectral indices. It was analyzed satellite data, particularly the MODIS Enhanced Vegetation Index (EVI) and related it to stocking rate records from SENASA. This work evidences the relationship between the stocking rate and the spectral index EVI, indicator of the primary productivity of vegetation, at departmental scale in the natural areas of Monte and Espinal of La Pampa. Results indicate that in western region (Monte) there was an increment in the stocking rate at department level and a decrease in vegetation seasonality. It is posed that the higher grazing pressure led to the overgrazing of the most palatable herbaceous species, increasing the shrub proportion in landscape.La producción de cultivos está atravesando procesos de expansión e intensificación alrededor de todo el planeta. En consecuencia, la producción ganadera está siendo desplazada hacia tierras marginales de menor capacidad de carga. El objetivo de este trabajo es evaluar la estacionalidad de la vegetación en la provincia de La Pampa, ubicada en la región semiárida argentina; y explorar si las variaciones en la estacionalidad están relacionadas con la carga de ganado vacuno. Se plantea como hipótesis que los cambios en la carga animal y la presión de pastoreo alteran la proporción de diferentes grupos funcionales de vegetación, y de esta manera, su estacionalidad. Se predice que el sobrepastoreo de los pastos más estacionales alterará la proporción de especies leñosas, y ello repercutirá sobre los índices espectrales. Se analizó la información satelital, particularmente el Índice de Vegetación Mejorado (EVI) de MODIS y se lo relacionó con los registros de carga animal de SENASA. Este trabajo evidencia la relación entre la carga animal y el EVI, indicador de la productividad primaria de la vegetación, a la escala de departamento en las áreas naturales del Monte y el Espinal de La Pampa. Los resultados indican que al oeste de la provincia (Monte) hubo un aumento de la carga animal y una disminución de la estacionalidad de la vegetación a escala de departamento. La mayor presión de pastoreo habría conducido al sobrepastoreo de las especies herbáceas más palatables aumentando la proporción de arbustos en el paisaje.Fil: Di Bella, Carlos Marcelo. Instituto Nacional de Tecnología Agropecuaria (Argentina)Fil: Beget, María Eugenia. Instituto Nacional de Tecnología Agropecuaria (Argentina)Fil: Campos, Alfredo Nicolás. Instituto Nacional de Tecnología Agropecuaria (Argentina)Fil: Viglizzo, Ernesto. Consejo Nacional de Investigaciones Científicas y TécnicasFil: Jobbágy, Esteban. Consejo Nacional de Investigaciones Científicas y TécnicasFil: García, Alfredo Gabriel. Instituto Nacional de Tecnología Agropecuaria (Argentina)Fil: Cotroneo, Santiago. Instituto Nacional de Tecnología Agropecuaria (Argentina

COMPARATIVE STUDY ON THE TREATMENT OF DISC HERNIATIONS

ABSTRACT Objective: To compare the results of treatment of patients with low back pain and radiculalgia resulting from disc herniation associated with disc degeneration through instrumentation with pedicle screws and dynamic rod, with root release and without diskectomy compared with other non-instrumented techniques (microdiskectomy with or without foraminotomy). Methods: This is a retrospective descriptive study of interventions for patients with herniated discs in the Traumatology and Neurosurgery that used the following variables: age, sex, type of technique, surgical time, time of evolution, degree of satisfaction, and complications. Two groups were formed: instrumentation with dynamic rods and non-instrumented techniques, comparing the results of each group. The software used was the SPSS v20.0. Results: We presented 142 interventions carried out between 2009 and 2012, 86 with dynamic instrumentation and 56 by other decompression techniques without instrumentation. No statistically significant differences were observed between age and sex groups and time elapsed until intervention. We found statistically significant differences (p=0.001) in surgical time, which was lower in the instrumented technique. No significant differences were found in complications between the techniques in both re-operations and in infections. Conclusions: In this study, we found no significant differences between the use of instrumentation with dynamic rods with respect to other non-instrumented surgical techniques in the treatment of herniated discs over 6 months of evolution or the complications and the degree of the patients' satisfaction

The Evolutionary Landscape of SARS-CoV-2 Variant B.1.1.519 and Its Clinical Impact in Mexico City

The SARS-CoV-2 pandemic is one of the most concerning health problems around the globe. We reported the emergence of SARS-CoV-2 variant B.1.1.519 in Mexico City. We reported the effective reproduction number (Rt) of B.1.1.519 and presented evidence of its geographical origin based on phylogenetic analysis. We also studied its evolution via haplotype analysis and identified the most recurrent haplotypes. Finally, we studied the clinical impact of B.1.1.519. The B.1.1.519 variant was predominant between November 2020 and May 2021, reaching 90% of all cases sequenced in February 2021. It is characterized by three amino acid changes in the spike protein: T478K, P681H, and T732A. Its Rt varies between 0.5 and 2.9. Its geographical origin remain to be investigated. Patients infected with variant B.1.1.519 showed a highly significant adjusted odds ratio (aOR) increase of 1.85 over non-B.1.1.519 patients for developing a severe/critical outcome (p = 0.000296, 1.33–2.6 95% CI) and a 2.35-fold increase for hospitalization (p = 0.005, 1.32–4.34 95% CI). The continuous monitoring of this and other variants will be required to control the ongoing pandemic as it evolves

The Evolutionary Landscape of SARS-CoV-2 Variant B.1.1.519 and Its Clinical Impact in Mexico City

The SARS-CoV-2 pandemic is one of the most concerning health problems around the globe. We reported the emergence of SARS-CoV-2 variant B.1.1.519 in Mexico City. We reported the effective reproduction number (Rt) of B.1.1.519 and presented evidence of its geographical origin based on phylogenetic analysis. We also studied its evolution via haplotype analysis and identified the most recurrent haplotypes. Finally, we studied the clinical impact of B.1.1.519. The B.1.1.519 variant was predominant between November 2020 and May 2021, reaching 90% of all cases sequenced in February 2021. It is characterized by three amino acid changes in the spike protein: T478K, P681H, and T732A. Its Rt varies between 0.5 and 2.9. Its geographical origin remain to be investigated. Patients infected with variant B.1.1.519 showed a highly significant adjusted odds ratio (aOR) increase of 1.85 over non-B.1.1.519 patients for developing a severe/critical outcome (p = 0.000296, 1.33–2.6 95% CI) and a 2.35-fold increase for hospitalization (p = 0.005, 1.32–4.34 95% CI). The continuous monitoring of this and other variants will be required to control the ongoing pandemic as it evolves

Estado-Nación en México : independencia y revolución

Durante el año 2010 se vivió un conjunto de actividades encaminadas a celebrar dos acontecimientos que han marcado la vida de México: el inicio de las luchas armadas de Independencia en 1810 y de la Revolución mexicana en 1910. En este marco se desarrollaron acciones diversas. El interesado pudo encontrar películas en dibujos animados proyectadas en las cadenas de cine comercial, exposiciones fotográicas históricas o espectáculos masivos en espacios públicos por mencionar algunos

Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy

Abstract Background Previous studies by our group have shown that oxidative phosphorylation (OXPHOS) is the main pathway by which pancreatic cancer stem cells (CSCs) meet their energetic requirements; therefore, OXPHOS represents an Achille’s heel of these highly tumorigenic cells. Unfortunately, therapies that target OXPHOS in CSCs are lacking. Methods The safety and anti-CSC activity of a ruthenium complex featuring bipyridine and terpyridine ligands and one coordination labile position (Ru1) were evaluated across primary pancreatic cancer cultures and in vivo, using 8 patient-derived xenografts (PDXs). RNAseq analysis followed by mitochondria-specific molecular assays were used to determine the mechanism of action. Results We show that Ru1 is capable of inhibiting CSC OXPHOS function in vitro, and more importantly, it presents excellent anti-cancer activity, with low toxicity, across a large panel of human pancreatic PDXs, as well as in colorectal cancer and osteosarcoma PDXs. Mechanistic studies suggest that this activity stems from Ru1 binding to the D-loop region of the mitochondrial DNA of CSCs, inhibiting OXPHOS complex-associated transcription, leading to reduced mitochondrial oxygen consumption, membrane potential, and ATP production, all of which are necessary for CSCs, which heavily depend on mitochondrial respiration. Conclusions Overall, the coordination complex Ru1 represents not only an exciting new anti-cancer agent, but also a molecular tool to dissect the role of OXPHOS in CSCs. Results indicating that the compound is safe, non-toxic and highly effective in vivo are extremely exciting, and have allowed us to uncover unprecedented mechanistic possibilities to fight different cancer types based on targeting CSC OXPHOS