9 research outputs found
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Engaging the community in multidisciplinary TEL research: a case-study from networking in Europe
The STELLAR Network of Excellence was launched in February 2009 with the explicit intention of Sustaining Large Scale Multi-Disciplinary Research in Technology Enhanced Learning. So as to support this aim, the network has defined a number of different activity tracks, aimed at building capacity amongst senior-level researchers/decision makers, mid-level researchers and junior researchers/PhD students as well with a separate track dedicated to building community level capacity. In the abstract, the ‘community’ around any research study might usually be defined as the subject of the research. However, the focus of the community-capacity building activities of STELLAR, considers the role of the community as object of the research – a main consumer of the products of research, and having a stake in setting the research agenda itself. Thus, on the one hand, the STELLAR consortium needs to inform its actions and activities based on needs and wishes of stakeholders, while at the same time it intends to mobilise the same stakeholders, to forge common policy positions with respect to future development of TEL in Europe. This paper takes these activities as a case-study in structured social-network design, and considers the impact such activities may have on the field of technology enhanced learning in the coming years. The data is based on the first year of activities of the network, which are intended to last 40 months and are designed around the overlapping activities of connecting, orchestrating and contextualising stakeholders. The paper describes the elements of the stakeholder engagement plan as deployed by the STELLAR network in TELeurope, the activities conducted so far, and the plans for the future. It explains the consortium’s approach to stakeholder analysis, particularly the adaptation of existing methodologies, to produce a numerical ranking of stakeholders, by ‘alliance potential’. With regards to TELeurope, an emerging social platform being deployed by the STELLAR consortium so as to help this process of networking, it explains the current state of the affairs and plans for development of the platform, while referencing the work of Svensen & Laberge, and adapts the work of Bryson to contextualise these activities within a broader theoretical framework. Finally, the paper considers the quality monitoring elements and evaluation approach of the consortium, and makes recommendations as to how the networking strategy can be further energised, and as to how the process of evaluation can be improved. It concludes that the TELeurope strategy shows a high potential for stimulating engagement of stakeholders, subject to a number of caveats, which can be avoided through judicious policy choices within the next year
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
Policy Challenges for Professional Higher Education in Central and South-Eastern Europe
PROCSEE is a policy-oriented project, aimed at strengthening the provision of professional higher education, by strengthening the policy-work conducted by umbrella organizations representing professional higher education institutions in Central and South-Eastern in Europe. Working together over three years, the project intends to: identify the main challenges facing PHE in the region, propose policy solutions to address those challenges in the short-to-midterm, through a mixture of good-practice identification and stakeholder consultation, bring together the main actors in PHE in each participating country, so as to build implementation roadmaps for the identified policy solutions. The result of the first year of activities of the project, this document outlines the main challenges facing professional higher education in the CSEE region, with the aim of highlighting potential areas for reform in the next project phases. (DIPF/Orig.
Modelling a stakeholder community via a social platform: The case of TELeurope.eu
Past attempts at creating stakeholder networks for specific fields of research or industrial sectors have shown to be a resource-consuming and time-consuming process, which requires continuous monitoring and political efforts, as well as the trial-and-error deployment of technological tools. Still, these networks are thought to be an efficient and essential communication instrument for addressing challenges and building capacities. The EU FP7 STELLAR Network of Excellence has the mission of establishing a network for Technology Enhanced Learning (TEL) stakeholders, and has decided to do so via an online social community called TELeurope. In this paper we provide an overview of some relevant experience in establishing collaborative networks in the fields of business sciences, learning networks and communities of practice and reflect on our experience thus far with TELeurope