Marriage and Family

Važnost koju Biblija pridaje braku i obitelji vidi se iz činjenice da se sedam od Deset zapovijedi Božjeg moralnog zakona bavi njihovim funkcijama. To su: druga zapovijed koja govori o nastojanju roditelja da osiguraju blagostanje svojoj djeci; četvrta zapovijed koja upućuje obitelj na svetkovanje subote; peta koja od djece zahtijeva da poštuju roditelje i deseta koja zabranjuje poželjeti išta što pripada drugom domaćinstvu. Tri od preostalih šest, iako neposredno ne spominju članove obitelji, daju jasne smjernice za uređivanje obiteljskih odnosa. Sedma zapovijed zabranjuje preljub, osma krađu, dok deveta zabranjuje pogrešno prikazivanje bližnjega. Dodatni dokaz posebnog božanskog zanimanja za brak i obitelj nalazimo u činjenici da je Krist, koji je stvorio ljudski rod (Kol 1,16) i kao veliki JA JESAM proglasio moralni Zakon pravilom ponašanja (Iv 8,58; Izl 31,14.18), iskoristio svadbu kao sredinu u kojoj će učiniti svoje prvo čudo (Iv 2,1-11). I propisom i primjerom Sveto pismo jasno pokazuje Božju brigu za dobrobit doma. Budući da je struktura obitelji u biblijska vremena često bila izopačenje Božjeg iskonskog plana, ne možemo sve biblijske obitelji uzeti kao primjer. Moramo razlikovati apsolutne ideale božanske namjere od relativnih prilagodbi nakon pada u grijeh. Pa ipak, pojedinac koji uz molitvu proučava biblijska načela o obitelji, naći će odgovarajuće vrlo korisne smjernice.The priority that Scripture places upon mar¬riage and family concerns is seen in the fact that seven of the Ten Commandments—God’s moral law—reference its functions. They are: commandment number 2, which relates the actions of parents to the prosperity of their children; number 4, which directs the family to Sabbath obedience; number 5, which man-dates respect of children for parents; and number 10, which prohibits coveting anything belonging to another’s household. Three of the remaining six, while not specifically nam¬ing family members, give explicit guidance for family relations. Number 7 prohibits adultery; number 8 rules against stealing; and number 9 forbids the misrepresentation of one’s neighbor. An additional evidence of divine regard for marriage and family concerns is seen in the fact that Christ, who created the human race (Col. 1:16) and as the great “I AM” provided the moral law as guide for its conduct (John 8:58; Ex. 31:14, 18), utilized the marriage cer¬emony as the setting for His inaugural miracle (John 2:1-11). Both by precept and example the Scriptures make clear God’s concern for the welfare of the home. Since the family structures of Bible days often were distortions of God’s original plan, one cannot take all biblical families as models. It is necessary to differentiate between the absolutes of divine intent and the relative ac¬commodations that devolved after sin. Never-theless, the individual who prayerfully studies scriptural principles regarding the family will find relevant and effective guidance

Marriage and Family

Važnost koju Biblija pridaje braku i obitelji vidi se iz činjenice da se sedam od Deset zapovijedi Božjeg moralnog zakona bavi njihovim funkcijama. To su: druga zapovijed koja govori o nastojanju roditelja da osiguraju blagostanje svojoj djeci; četvrta zapovijed koja upućuje obitelj na svetkovanje subote; peta koja od djece zahtijeva da poštuju roditelje i deseta koja zabranjuje poželjeti išta što pripada drugom domaćinstvu. Tri od preostalih šest, iako neposredno ne spominju članove obitelji, daju jasne smjernice za uređivanje obiteljskih odnosa. Sedma zapovijed zabranjuje preljub, osma krađu, dok deveta zabranjuje pogrešno prikazivanje bližnjega. Dodatni dokaz posebnog božanskog zanimanja za brak i obitelj nalazimo u činjenici da je Krist, koji je stvorio ljudski rod (Kol 1,16) i kao veliki JA JESAM proglasio moralni Zakon pravilom ponašanja (Iv 8,58; Izl 31,14.18), iskoristio svadbu kao sredinu u kojoj će učiniti svoje prvo čudo (Iv 2,1-11). I propisom i primjerom Sveto pismo jasno pokazuje Božju brigu za dobrobit doma. Budući da je struktura obitelji u biblijska vremena često bila izopačenje Božjeg iskonskog plana, ne možemo sve biblijske obitelji uzeti kao primjer. Moramo razlikovati apsolutne ideale božanske namjere od relativnih prilagodbi nakon pada u grijeh. Pa ipak, pojedinac koji uz molitvu proučava biblijska načela o obitelji, naći će odgovarajuće vrlo korisne smjernice.The priority that Scripture places upon mar¬riage and family concerns is seen in the fact that seven of the Ten Commandments—God’s moral law—reference its functions. They are: commandment number 2, which relates the actions of parents to the prosperity of their children; number 4, which directs the family to Sabbath obedience; number 5, which man-dates respect of children for parents; and number 10, which prohibits coveting anything belonging to another’s household. Three of the remaining six, while not specifically nam¬ing family members, give explicit guidance for family relations. Number 7 prohibits adultery; number 8 rules against stealing; and number 9 forbids the misrepresentation of one’s neighbor. An additional evidence of divine regard for marriage and family concerns is seen in the fact that Christ, who created the human race (Col. 1:16) and as the great “I AM” provided the moral law as guide for its conduct (John 8:58; Ex. 31:14, 18), utilized the marriage cer¬emony as the setting for His inaugural miracle (John 2:1-11). Both by precept and example the Scriptures make clear God’s concern for the welfare of the home. Since the family structures of Bible days often were distortions of God’s original plan, one cannot take all biblical families as models. It is necessary to differentiate between the absolutes of divine intent and the relative ac¬commodations that devolved after sin. Never-theless, the individual who prayerfully studies scriptural principles regarding the family will find relevant and effective guidance

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

18FDG positron emission tomography mining for metabolic imaging biomarkers of radiation-induced xerostomia in patients with oropharyngeal cancer

Purpose: Head and neck cancers radiotherapy (RT) is associated with inevitable injury to parotid glands and subsequent xerostomia. We investigated the utility of SUV derived from 18FDG-PET to develop metabolic imaging biomarkers (MIBs) of RT-related parotid injury. Methods: Data for oropharyngeal cancer (OPC) patients treated with RT at our institution between 2005 and 2015 with available planning computed tomography (CT), dose grid, pre- &amp; first post-RT 18FDG-PET-CT scans, and physician-reported xerostomia assessment at 3–6 months post-RT (Xero 3–6 ms) per CTCAE, was retrieved, following an IRB approval. A CT-CT deformable image co-registration followed by voxel-by-voxel resampling of pre &amp; post-RT 18FDG activity and dose grid were performed. Ipsilateral (Ipsi) and contralateral (contra) parotid glands were sub-segmented based on the received dose in 5 Gy increments, i.e. 0–5 Gy, 5–10 Gy sub-volumes, etc. Median and dose-weighted SUV were extracted from whole parotid volumes and sub-volumes on pre- &amp; post-RT PET scans, using in-house code that runs on MATLAB. Wilcoxon signed-rank and Kruskal-Wallis tests were used to test differences pre- and post-RT. Results: 432 parotid glands, belonging to 108 OPC patients treated with RT, were sub-segmented &amp; analyzed. Xero 3–6 ms was reported as: non-severe (78.7%) and severe (21.3%). SUV- median values were significantly reduced post-RT, irrespective of laterality (p = 0.02). A similar pattern was observed in parotid sub-volumes, especially ipsi parotid gland sub-volumes receiving doses 10–50 Gy (p < 0.05). Kruskal-Wallis test showed a significantly higher mean RT dose in the contra parotid in the patients with more severe Xero 3-6mo (p = 0.03). Multiple logistic regression showed a combined clinical-dosimetric-metabolic imaging model could predict the severity of Xero 3-6mo; AUC = 0.78 (95%CI: 0.66–0.85; p < 0.0001). Conclusion: We sought to quantify pre- and post-RT 18FDG-PET metrics of parotid glands in patients with OPC. Temporal dynamics of PET-derived metrics can potentially serve as MIBs of RT-related xerostomia in concert with clinical and dosimetric variables

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least 4 m. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the 6.5 m James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 yr, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit