Uji Efikasi Herbisida Glifosat Terhadap Pertumbuhan Dan Produksi Beberapa Varietas Jagung Produk Rekayasa Genetika

The study on the efficacy of glyphosate on the growth and yield of genetically modified corn varieties. The study aims to determine the efficacy of glyphosate on the growth and yield two varieties of genetically modified corn. The study was carried out at “Balai Benih Induk”, Tanjung Selamat, Medan from March to June 2012. Four treatments namely stacked genetically modified corn “X” x genetically modified corn “Y” (sprayed with glyphosate), genetically modified corn “X” (no glyphosate application, manual weeding), genetically modified corn “Y” (sprayed with glyphosate), hybrid DK979 (no glyphosate application, manual weeding). The result showed that glyphosate did not affect genetically modified corn

A Real-time Image Reconstruction System for Particle Treatment Planning Using Proton Computed Tomography (pCT)

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range uncertainty margins are around 3.5%, pCT has the potential to provide more accurate measurements to within 1%. This improved efficiency will be beneficial to proton-therapy planning and pre-treatment verification. A prototype pCT imaging device has recently been developed capable of rapidly acquiring low-dose proton radiographs of head-sized objects. We have also developed an advanced, fast image reconstruction software based on distributed computing that utilizes parallel processors and graphical processing units. The combination of fast data acquisition and fast image reconstruction will enable the availability of RSP images within minutes for use in clinical settings. The performance of our image reconstruction software has been evaluated using data collected by the prototype pCT scanner from several phantoms.Comment: Paper presented at Conference on the Application of Accelerators in Research and Industry, CAARI 2016, 30 October to 4 November 2016, Ft. Worth, TX, US

Pengaruh Konsep Diri Dalam Komunikasi Interpersonal Pustakawan Hubungannya Terhadap Kepuasan Pemustaka Di Badan Perpustakaan Dan Kearsipan Daerah Kota Cirebon

Salah satu indikasi bahwa manusia sebagai makhluk sosial, adalah komunikasi antar manusia. Komunikasi sangat penting untuk menentukan kualitas layanan perpustakaan yang ideal, khususnya komunikasi interpersonal. Komunikasi interpersonal di perpustakaan bisa antara pustakawan dengan pimpinan, pustakawan dengan pustakawan, maupun pustakawan dengan pemustaka. Pustakawan harus memiliki kemampuan komunikasi interpersonal, agar terciptanya komunikasi yang lebih baik agar tidak menyinggung perasaan, berbicara dengan sopan, dan melayani pemustaka dengan sungguh-sungguh. Penelitian ini dilakukan di Badan Perpustakaan dan Kearsipan Daearah Kota Cirebon. Penelitian ini bertujuan untuk mengetahui apakah konsep diri dalam kemampuan komunikasi interpersonal pustakawan mempengaruhi kepuasan pemustaka. Metode yang dilakukan dalam penelitian ini adalah metode deskriptif kuantitatif. Teknik pengambilan sampel menggunakan insidental, dengan jumlah jumlah sampel 96 orang. Teknik pengumpulan datanya dengan kuesioner, dan analisis datanya secara statistik menggunakan alat bantu SPSS versi 1.6. Uji hipotesis menggunakan uji t dan analisis jalur. Dari hasil penelitian ini dapat diketahui bahwa konsep diri tidak dapat langsung berpengaruh terhadap kepuasan pemustaka melainkan harus melalui komunikasi interpersonal terlebih dahulu

Hubungan Jumlah Bakteri Patogen dalam Rumah dengan Kejadian Pneumonia pada Balita di Wilayah Kerja Puskesmas Ngesrep Banyumanik Semarang Tahun 2014

Background : Pneumonia is an acute respiratory tract infections, in which there is inflammation in the lung tissue, caused by microorganisms such as viruses, bacteria, fungi, inhaled foreign particles or irradiation. Semarang is a city with a high incidence of pneumonia, subdistrict Banyumanik is a district with a high incidence rate is 103.25 per 1000 population in 2012. Methods : This is an observasional reseach using case control design. The population in this research is 162 children under five years, using Random Sampling techniques, a sample of 70 children under five years.The data collection method in this research is the measurement by using the colony counter, lux metter, thermohygrometer, observations, questionnaires, interviews, and documentation. And data analysis in this study using chi square test and logistic regression test. Results : The results showed there was no significant relationship between the amount of bacterial pathogen in the house with incidence of pneumonia onchildren under five years with p value (0.356); OR (4.387); CI 95% (0.465-41.404) for Staphilococcus aureus, p value (0.112); OR (2.364), CI 95% (0.807-6.927) for Klebsiella pneumoniae, and p value (0.473); OR (1.410); CI 95% (0.551) for Pseudomonas aeruginosa. No significant relationship between temperature, lighting, and ventilation with the incidence of pneumonia on children under five years with p value (0.101);OR (2.522);CI 95% (0.821-7.748), p (0.614); OR (3.188); CI 95% (0.315-32.144), p (0.632); OR (0.795); CI 95% (0.311-2.034). Any relationship humidity with pneumonia the incidence of pneumonia on children under five years with p value (0.012); OR (0.265), CI 95% (0.092-0.765). Conslusion : The conclution of this reseach is a significant relationship between humidity with pneumonia on children under five years in working areas Public Health Center Ngesrep Banyumanik Semarang 2014

The effects of peripheral and central high insulin on brain insulin signaling and amyloid-β in young and old APP/PS1 mice

Hyperinsulinemia is a risk factor for late-onset Alzheimer's disease (AD). In vitro experiments describe potential connections between insulin, insulin signaling, and amyloid-β (Aβ), but in vivo experiments are needed to validate these relationships under physiological conditions. First, we performed hyperinsulinemic-euglycemic clamps with concurrent hippocampal microdialysis in young, awake, behaving APP(swe)/PS1(dE9) transgenic mice. Both a postprandial and supraphysiological insulin clamp significantly increased interstitial fluid (ISF) and plasma Aβ compared with controls. We could detect no increase in brain, ISF, or CSF insulin or brain insulin signaling in response to peripheral hyperinsulinemia, despite detecting increased signaling in the muscle. Next, we delivered insulin directly into the hippocampus of young APP/PS1 mice via reverse microdialysis. Brain tissue insulin and insulin signaling was dose-dependently increased, but ISF Aβ was unchanged by central insulin administration. Finally, to determine whether peripheral and central high insulin has differential effects in the presence of significant amyloid pathology, we repeated these experiments in older APP/PS1 mice with significant amyloid plaque burden. Postprandial insulin clamps increased ISF and plasma Aβ, whereas direct delivery of insulin to the hippocampus significantly increased tissue insulin and insulin signaling, with no effect on Aβ in old mice. These results suggest that the brain is still responsive to insulin in the presence of amyloid pathology but increased insulin signaling does not acutely modulate Aβ in vivo before or after the onset of amyloid pathology. Peripheral hyperinsulinemia modestly increases ISF and plasma Aβ in young and old mice, independent of neuronal insulin signaling. SIGNIFICANCE STATEMENT The transportation of insulin from blood to brain is a saturable process relevant to understanding the link between hyperinsulinemia and AD. In vitro experiments have found direct connections between high insulin and extracellular Aβ, but these mechanisms presume that peripheral high insulin elevates brain insulin significantly. We found that physiological hyperinsulinemia in awake, behaving mice does not increase CNS insulin to an appreciable level yet modestly increases extracellular Aβ. We also found that the brain of aged APP/PS1 mice was not insulin resistant, contrary to the current state of the literature. These results further elucidate the relationship between insulin, the brain, and AD and its conflicting roles as both a risk factor and potential treatment

The Implementation of Jigsaw Technique and Student Team Achievement Division (STAD) in Teaching Reading

The objectives of the research were aimed at finding out the responses the students had during the implementation of Jigsaw technique and Student Team Achievement Division (STAD). This research was done through a qualitative design. The population of this research was the second grade students at SMPN 1 Abung Surakarta. The result showed that there were some obstacles found during the implementation of the Jigsaw and STAD Technique as follows: (1) limited vocabulary knowledge; (2) difficulty level of the text (readability); (3) noisy class situation; (4) no students background knowledge; (5) hesitancy to express opinions; (6) class dominated by the smart students. The results showed that there were obstacles that students faced during teaching, and learning reading comprehension in the class using Jigsaw, and STAD Technique

Efficiency determination of resistive plate chambers for fast quasi-monoenergetic neutrons

Composite detectors made of stainless steel converters and multigap resistive plate chambers have been irradiated with quasi-monoenergetic neutrons with a peak energy of 175MeV. The neutron detection efficiency has been determined using two different methods. The data are in agreement with the output of Monte Carlo simulations. The simulations are then extended to study the response of a hypothetical array made of these detectors to energetic neutrons from a radioactive ion beam experiment.Comment: Submitted to Eur.Phys.J. A; upgraded version correcting some typos and updating ref.

Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo

Epidemiological studies show that patients with type 2 diabetes (T2DM) and individuals with a diabetes-independent elevation in blood glucose have an increased risk for developing dementia, specifically dementia due to Alzheimer’s disease (AD). These observations suggest that abnormal glucose metabolism likely plays a role in some aspects of AD pathogenesis, leading us to investigate the link between aberrant glucose metabolism, T2DM, and AD in murine models. Here, we combined two techniques — glucose clamps and in vivo microdialysis — as a means to dynamically modulate blood glucose levels in awake, freely moving mice while measuring real-time changes in amyloid-β (Aβ), glucose, and lactate within the hippocampal interstitial fluid (ISF). In a murine model of AD, induction of acute hyperglycemia in young animals increased ISF Aβ production and ISF lactate, which serves as a marker of neuronal activity. These effects were exacerbated in aged AD mice with marked Aβ plaque pathology. Inward rectifying, ATP-sensitive potassium (K(ATP)) channels mediated the response to elevated glucose levels, as pharmacological manipulation of K(ATP) channels in the hippocampus altered both ISF Aβ levels and neuronal activity. Taken together, these results suggest that K(ATP) channel activation mediates the response of hippocampal neurons to hyperglycemia by coupling metabolism with neuronal activity and ISF Aβ levels