1,122 research outputs found
Measuring diet in primary school children aged 8-11 years: validation of the Child and Diet Evaluation Tool (CADET) with an emphasis on fruit and vegetable intake.
Background/Objectives:The Child And Diet Evaluation Tool (CADET) is a 24-h food diary that measures the nutrition intake of children aged 3-7 years, with a focus on fruit and vegetable consumption. Until now CADET has not been used to measure nutrient intake of children aged 8-11 years. To ensure that newly assigned portion sizes for this older age group were valid, participants were asked to complete the CADET diary (the school and home food diary) concurrently with a 1-day weighed record. Subjects/Methods:A total of 67 children with a mean age of 9.3 years (s.d.: ± 1.4, 51% girls) participated in the study. Total fruit and vegetable intake in grams and other nutrients were extracted to compare the mean intakes from the CADET diary and Weighed record using t-tests and Pearson's r correlations. Bland-Altman analysis was also conducted to assess the agreement between the two methods. Results: Correlations comparing the CADET diary to the weighed record were high for fruit, vegetables and combined fruit and vegetables (r=0.7). The results from the Bland-Altman plots revealed a mean difference of 54 g (95% confidence interval: -88, 152) for combined fruit and vegetables intake. CADET is the only tool recommended by the National Obesity Observatory that has been validated in a UK population and provides nutrient level data on children's diets. Conclusions:The results from this study conclude that CADET can provide high-quality nutrient data suitable for evaluating intervention studies now for children aged 3-11 years with a focus on fruit and vegetable intake
Dietary value for money? Investigating how the monetary value of diets in the National Diet and Nutrition Survey (NDNS) relate to dietary energy density
Estimating the monetary value of individuals’ diets allows investigation into how costs relate to dietary quality. A number of studies(1–2), including one in Scotland(3), have reported a strong negative relationship between diet costs and energy density. Most studies of this type neglect to address the issue of mathematical coupling, where energy is both the numerator in the energy density variable (kJ/g) and the denominator in energy-adjusted diet cost (e.g. E/10 MJ). As a result, the findings could be reflecting a mathematical relationship(4).
This study investigated how estimated diet costs of NDNS adults relate to dietary energy density using the ‘residuals’ regressionmethod to account for energy. Diet diary information from 2008–2010 was matched to an in-house database of national average (2004) food prices (the DANTE cost database) to assign a cost to each food and non-alcoholic beverage consumed. Mean daily diet costs and costs per 10 MJ were calculated for each participant. Energy density (g/kJ) was derived from foods and milk.
The sample median diet cost was £2.84 per day (IQR £2.27, £3.64), or £4.05 per 10MJ (£3.45, £4.82). Values for energy density, food energy, and diet costs by quintiles of dietary energy density (1 = least energy dense) are presented in the table. Adjusted linear regression found a strong negative relationship: additional standard deviation above the diet cost expected for a given energy intake (the residual), there was an associated decrease in energy density of 0.46kJ/g (95% CI - 0.53, - 0.38, p<0.001).
This is the first time individual-level diet costs have been characterized for a representative British population. These diet costs represent the inherent value of the diet, and are not comparable to UK expenditure data. The analyses confirm a diet cost-energy density link that is not due to mathematical artefact, and suggest that those consuming more energy-dense diets are achieving more kilojoules for their money
Maternal iron status in early pregnancy and birth outcomes : insights from the Baby's Vascular health and Iron in Pregnancy study
Date of Acceptance: 16/03/2015 Acknowledgements N. A. A. was funded by a Wellcome Trust Research Training Fellowship (WT87789). H. J. M. and H. E. H. are supported by the Scottish Government’s Rural and Environment Science and Analytical Services. N. A. B. S. is supported by Cerebra. The authors’ contributions are as follows: N. A. A. was responsible for organising the study conduct, data collection and database management, performed the statistical analysis, interpreted the results and drafted the paper. N. A. A., N. A. B. S., J. E. C., H. J. M. and D. C. G. contributed to the study concept and design, and interpretation of results. H. J. M. and H. E. H. analysed the laboratory samples. J. E. C. and D. C. G. provided advice on statistical strategy and analysis. All authors have fully participated in the reporting stage and have critically reviewed and approved the final draft of the paper. The authors declare no conflict of interestPeer reviewedPublisher PD
Longitudinal photocurrent spectroscopy of a single GaAs/AlGaAs v-groove quantum wire
Modulation-doped GaAs v-groove quantum wires (QWRs) have been fabricated with
novel electrical contacts made to two-dimensional electron-gas (2DEG)
reservoirs. Here, we present longitudinal photocurrent (photoconductivity/PC)
spectroscopy measurements of a single QWR. We clearly observe conductance in
the ground-state one-dimensional subbands; in addition, a highly
temperature-dependent response is seen from other structures within the
v-groove. The latter phenomenon is attributed to the effects of structural
topography and localization on carrier relaxation. The results of
power-dependent PC measurements suggest that the QWR behaves as a series of
weakly interacting localized states, at low temperatures
Formative evaluation of the usability and acceptability of myfood24 among adolescents: a UK online dietary assessments tool
BackgroundMyfood24 is a new online 24 h dietary assessment tool developed for use among the UK population. Limited information is available on the usability and acceptability of such tools. Hence this study aims to determine the usability and acceptability of myfood24 among British adolescents (11-18y) before and after making the improvements.MethodsA total of 84 adolescents were involved in two stages. In stage-I (beta-version of myfood24), 14 adolescents were recruited, 7 of whom (group-1) were asked to enter standardized tasks in a testing room with screen capture software. The remaining 7-adolescents (group-2) were asked to report their previous food intake using myfood24 at home. All participants then completed a usability and acceptability questionnaire. Stage-II was carried out after making amendments to the live-version of myfood24 in which 70 adolescents were asked to enter their food intake for two days and then complete the same questionnaire. Thematic analysis was conducted of observer comments and open-ended questions.ResultsNavigation, presentation errors and failure to find functions were the main usability issues identified in the beta-version. Significant improvements were found in the usability and acceptability of most functions after implementing certain features like a spell checker, auto-fill option, and adding ‘mouse hover’ to help with the use of some functions. Adolescents’ perceptions of searching food items, selecting food portion sizes and making a list function were significantly improved in the live-version. The mean completion time of myfood24 reduced from 31 (SD?=?6) minutes in the beta-version to 16 (SD?=?5) minutes in the live-version. The mean system usability score (SUS) of myfood24 improved from 66/100 (95 % CI 60, 73) in the beta-version to 74/100 (95 % CI 71, 77) in the live-version, which is considered as ‘good’. Of the adolescents in stage-II, 41 % preferred using myfood24 to the interviewer-administered 24 h recall because myfood24 was quicker, easier to use and provided the adolescents with privacy when reporting dietary intake.ConclusionConsidering adolescents’ feedback has helped in improving the usability and acceptability of the final-version of myfood24. myfood24 appears to support adolescents’ need in reporting their dietary intake, which may potentially improve the overall quality of adolescents’ self-reported dietary information
Urinary Deoxynivalenol Is Correlated with Cereal Intake in Individuals from the United Kingdom
Background
Deoxynivalenol (DON) is a toxic fungal metabolite that frequently contaminates cereal crops. DON is toxic to animals, but the effects on humans are poorly understood, in part because exposure estimates are of limited precision.
Objectives
In this study we used the U.K. adult National Diet and Nutrition Survey to compare 24-hr urinary DON excretion with cereal intake.
Methods
One hundred subjects were identified for each of the following cereal consumption groups: low (mean, 107 g cereal/day; range, 88–125), medium (mean, 179 g/day; range, 162–195) and high (mean, 300 g/day; range, 276–325). DON was analyzed in 24-hr urine samples by liquid chromatography–mass spectrometry after purification on immunoaffinity columns.
Results
DON was detected in 296 of 300 (98.7%) urine samples. Cereal intake was significantly associated with urinary DON (p < 0.0005), with the geometric mean urinary levels being 6.55 μg DON/day [95% confidence interval (CI), 5.71–7.53]; 9.63 μg/day (95% CI, 8.39–11.05); and 13.24 μg/day (95% CI, 11.54–15.19) for low-, medium-, and high-intake groups, respectively. In multivariable analysis, wholemeal bread (p < 0.0005), white bread (p < 0.0005), “other” bread (p < 0.0005), buns/cakes (p = 0.003), high-fiber breakfast cereal (p = 0.016), and pasta (p = 0.017) were significantly associated with urinary DON. Wholemeal bread was associated with the greatest percent increase in urinary DON per unit of consumption, but white bread contributed approximately twice as much as wholemeal bread to the urinary DON levels because it was consumed in higher amounts.
Conclusion
The majority of adults in the United Kingdom appear to be exposed to DON, and on the basis of the urinary levels, we estimate that some individuals may exceed the European Union (EU) recommended maximum tolerable daily intake of 1,000 ng DON/kg (bw). This exposure biomarker will be a valuable tool for biomonitoring as part of surveillance strategies and in etiologic studies of DON and human disease risk
Comparison of open and closed book test for admission in medical school
Introduction
La maladie thromboembolique veineuse (MTEV) acquise à l’hôpital représente une part importante de morbi-mortalité évitable chez les patients hospitalisés en secteur médical. D’un autre côté, la thromboprophylaxie anticoagulante expose les patients à un risque hémorragique et majore les dépenses de santé. L’identification des patients hospitalisés à risque de MTEV est en cela cruciale. L’objectif de cette étude est d’évaluer de manière externe, les performances de 3 modèles de risque (score de Padua, Carpini et Improve) et de les comparer aux performances de l’âge pris isolément.
Patients et méthodes
Il s’agit d’une étude rétrospective sur une base de patients inclus prospectivement dans une étude randomisée en cluster sans intervention directe sur le patient. Les patients de plus de 40 ans, hospitalisé depuis les urgences en secteur médical plus de 48 h ont consécutivement été inclus et suivi à 3 mois. Les patients chez qui un diagnostic de MTEV avait été porté dans les 48 premières heures d’hospitalisation, ou ayant reçu un traitement anticoagulant pour une raison autre que la MTEV, ou encore ayant subi une chirurgie sous anesthésie générale ont été exclus. Les modèles de risques ont été calculés à posteriori. La réduction de mobilité a été déduite de la durée d’hospitalisation moins un jour. Le critère de jugement principal était la survenue d’un épisode thrombotique veineux symptomatique ou le décès brutal inexpliqué adjudiqué à 3 mois.
Résultats
Parmi les 14 910 patient éligibles, 14 659 (98,3) étaient évaluables. 263 (1,8 %) ont présenté une MTEV symptomatique ou un décès brutal inexpliqué. Les aires sous la courbe ROC étaient respectivement 0,60 [0,57–0,63], 0,62 [0,58–0,64] et 0,62 [0,59–0,65] pour les scores Caprini, Improve et Padua. Aucun de ces modèles n’a montré de performances supérieures à l’âge pris isolément (AUC 0,61 [0,58–0,64]). Ces résultats étaient similaires ne considérant que les évènements symptomatiques non fatals : (0,62 [0,58–0,66], 0,62 [0,58–0,66], 0,63 [0,59–0,67] et 0,58 [0,54–0,62]) ; ou dans le sous-groupe de patients ne recevant pas de thromboprophylaxie anticoagulante : 0,62 [0,58–0,67], 0,64 [0,60–0,68], 0,64 [0,59–0,68] et 0,66 [0,62–0,70] pour le score Caprini, Improve, Padua et l’âge, respectivement.
Conclusion
Les scores de Padua, Caprini et Improve ont des capacités de discrimination faible vis-à-vis de la MTEV acquise à l’hôpital, similaire à une évaluation se basant uniquement sur l’âge. Les meilleurs modèles de risque sont nécessaires
Evaluation of the impact of a school gardening intervention on children's fruit and vegetable intake: a randomised controlled trial.
Background: Current academic literature suggests that school gardening programmes can provide an interactive environment with the potential to change children’s fruit and vegetable intake. This is the first cluster randomised controlled trial (RCT) designed to evaluate whether a school gardening programme can have an effect on children’s fruit and vegetable intake.
Methods: The trial included children from 23 schools; these schools were randomised into two groups, one to receive the Royal Horticultural Society (RHS)-led intervention and the other to receive the less involved Teacher-led intervention. A 24-hour food diary (CADET) was used to collect baseline and follow-up dietary intake 18 months apart. Questionnaires were also administered to evaluate the intervention implementation.
Results: A total of 641 children completed the trial with a mean age of 8.1 years (95% CI: 8.0, 8.4). The unadjusted results from multilevel regression analysis revealed that for combined daily fruit and vegetable intake the Teacher-led group had a higher daily mean change of 8 g (95% CI: −19, 36) compared to the RHS-led group -32 g (95% CI: −60, −3). However, after adjusting for possible confounders this difference was not significant (intervention effect: −40 g, 95% CI: −88, 1; p = 0.06). The adjusted analysis of process measures identified that if schools improved their gardening score by 3 levels (a measure of school gardening involvement - the scale has 6 levels from 0 ‘no garden’ to 5 ‘community involvement’), irrespective of group allocation, children had, on average, a daily increase of 81 g of fruit and vegetable intake (95% CI: 0, 163; p = 0.05) compared to schools that had no change in gardening score.
Conclusions: This study is the first cluster randomised controlled trial designed to evaluate a school gardening intervention. The results have found very little evidence to support the claims that school gardening alone can improve children’s daily fruit and vegetable intake. However, when a gardening intervention is implemented at a high level within the school it may improve children’s daily fruit and vegetable intake by a portion. Improving children’s fruit and vegetable intake remains a challenging task
Fast Purcell-enhanced single photon source in 1,550-nm telecom band from a resonant quantum dot-cavity coupling
High-bit-rate nanocavity-based single photon sources in the 1,550-nm telecom
band are challenges facing the development of fibre-based long-haul quantum
communication networks. Here we report a very fast single photon source in the
1,550-nm telecom band, which is achieved by a large Purcell enhancement that
results from the coupling of a single InAs quantum dot and an InP photonic
crystal nanocavity. At a resonance, the spontaneous emission rate was enhanced
by a factor of 5 resulting a record fast emission lifetime of 0.2 ns at 1,550
nm. We also demonstrate that this emission exhibits an enhanced anti-bunching
dip. This is the first realization of nanocavity-enhanced single photon
emitters in the 1,550-nm telecom band. This coupled quantum dot cavity system
in the telecom band thus provides a bright high-bit-rate non-classical single
photon source that offers appealing novel opportunities for the development of
a long-haul quantum telecommunication system via optical fibres.Comment: 16 pages, 4 figure
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