1,636 research outputs found

    Study of the segmentation of images of anatomical microstructure of wood with multiresolution analysis

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    Existen abundantes problemáticas en el territorio nacional como lo son por ejemplo: el poco desarrollo forestal, la carente explotación comercial de un mercado maderero, el déficit en la preservación del medio ambiente, tráfico ilegal de especies y demás. Todas las anteriores se relacionan directamente con la falta de conocimiento para el desarrollo forestal, dado principalmente en la caracterización oportuna de una especie para poder llegar a la identificación y clasificación de manera acertada. Solo personas expertas, con amplios conocimientos de la anatomía microscópica típica de una muestra de madera pueden llegar a hacer una caracterización para su identificación. Este proceso puede ser arduo, requerir demasiado tiempo y brindar un nivel de error no aceptable. Para mejorar estos y otros aspectos, se busca brindar aportes para la consolidación de una herramienta que logre una caracterización con herramientas computacionales, que optimicen los procesos establecidos para la identificación del leño y brinden un buen porcentaje de acierto. En este proyecto se establecen una serie de condiciones iniciales por medio de un preprocesamiento necesario para el estudio de cada imagen representativa de cada muestra. Dentro de cada imagen se busca segmentar o visualizar objetos de interés; en este caso estos objetos están dados únicamente por los elementos de la microestructura conocidos como poros. Por medio del uso del análisis multiresolución (MRA, Multi-Resolution Analysis) mediante el uso de transformadas wavelet discretas DWT (Discrete wavelet Transform), más específicamente con la transformada de Daubechies. Se propone establecer un modelo de segmentación con el ánimo de evaluar su efectividad y concluir acerca de su utilidad como una herramienta al servicio del procesamiento digital de imágenes. Se utilizó el Análisis ROC (Receiver Operating Characteristic) mediante teoría de decisión, la cual considera minuciosamente todas las pruebas obtenidas en todo el banco de imágenes de estudio comparadas con su respectiva segmentación manual (efectuadas con un nivel de experiencia), con el ánimo de clasificar correctamente para los casos de respuesta positiva o negativa a la segmentación automática.There are many problems in the national territory such as: low forest development, commercial exploitation of timber market, lack of conservation of the environment, illegal trafficking of species and others. All of the above are directly related to the lack of knowledge for forestry development, mainly given in the characterization of a species to arrive at the correctly identification and classification. Only experts, with extensive knowledge of the microscopic anatomy From a sample of wood can make a characterization for identification. This process can be arduous, take too much time, and provide an unacceptable level of error. To improve these and other aspects, we seek to provide contributions for the consolidation of a tool that registers the characterization with computational tools, which optimizes the processes established for the identification and provides a good percentage of success. This project establishes a series of initial conditions by means of a pre-processing necessary for the study of each representative image of each sample. Within each image is sought to segment or view objects of interest; In this case these objects are given by the elements of the microstructure known as the pores. Through the use of multiresolution analysis (MRA) by the use of discrete wavelet transformer (DWT), specifically with Daubechies transformation. It is proposed to establish a segmentation model with the aim of evaluating its effectiveness and concluding about its usefulness as a tool for the digital image processing service. We used the Functional Characteristics of the receiver ( ROC) which minutely considers all the tests obtained in the whole bank of study images compared to their respective manual segmentation, with the aim of correctly classifying the cases of the positive or Negative response to automatic segmentation

    Short-term effects of text-background color combinations on the dynamics of the accommodative response

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    The purpose of the present study was to assess the accommodative response and pupillary dynamics while reading passages with different text-background color combinations on an LCD screen. Twenty healthy young adults read fourteen 2-min passages designed with fourteen different color combinations between text and background, while the accommodative and pupil responses were continuously measured with a binocular open-field autorefractometer. Our results revealed that the text-background color combination modulates the accommodative and pupillary dynamics during a 2-minutes reading task. The blue-red combination induced a heightened accommodative response, whereas positive polarities were associated with more variability of the accommodative response and smaller pupil sizes. Participants reported lower perceived ratings of legibility for text-background color combination with lower luminance contrast (white-yellow). The manipulation of text-background color did not have a significant effect on reading speed. These results may have important applications in the design of digital visual interfaces.This research was supported by the Spanish Ministry of Science, Innovation and Universities, with support from European Regional Development Fund (ERDF), RTI2018-094738-B-I00 project

    “I feel guilty”. Exploring guilt-related dynamics in family caregivers of people with dementia

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    Objectives: Family caregivers of people with dementia often report feelings of guilt. However, the number of studies analyzing guilt and the factors associated with its appearance are scarce. The aim of this study is to explore the subjective experience of guilt in the family care of people with dementia. Methods: A qualitative analysis of the narratives of 13 family caregivers of people with dementia about their feelings of guilt was done. Results: Seven categories for understanding guilt in caregiving were obtained: guilt derived from actions themselves; guilt derived from one’s limitations; guilt for feeling negative emotions; guilt associated with the change in the relationship with the person cared for; guilt for neglecting other areas; guilt induced by the person cared for, and guilt induced by others. The results showed the existence of cases in which guilt is absent by distress-avoiding processes. Conclusions: Guilt is a relevant variable in understanding caregiver distress, and its analysis is necessary for therapeutic work in the field of care. Clinical implications: Psychological interventions aimed at family caregivers should include specific techniques in order to address guilt feelings.The study was supported by the Spanish Ministry of Economy and Competiveness (grants PSI2015-65,152-C2-1-R and PSI2015-65,152-C2-2-R

    Estimation of the Mass Concentration of Volcanic Ash Using Ceilometers: Study of Fresh and Transported Plumes from La Palma Volcano

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    This study presents a synergistic approach to the study of the aerosol optical and microphysical properties measured in La Palma, Spain, during the 2021 eruption of the Cumbre Vieja volcano (from 19 September to 13 December 2021). This study aims to characterize the different phases of the volcanic eruption using the spatio-temporal evolution of the event together with the mass concentration quantification of four different atmospheric layers. The impact of the plume’s pathway that reached the South of France is analyzed. Here, passive and active remote sensors were used, namely CL51 and CL61 ceilometers and AERONET sunphotometers. The attenuated backscattering ranged from 0.8 to 9.1 × 10−6 (msr)−1 and the volume depolarization ratio measured nearby the volcano was up to 0.3. The ash plume remained within the first 4 km agl, with intense episodes that reached mean aerosol optical depth values of up to 0.4. Thirteen study cases were selected where coarse mode was dominant over fine mode. For the data selection, the fine and coarse lidar ratios found were 3.9 ± 0.8 and 21.0 ± 3.8 sr in the north and 6.9 ± 1.8 and 30.1 ± 10.3 sr in the south. The ash mass concentration reached moderate levels with maximum values of up to 313.7 μgm−3.This work was financially supported by ONERA within the framework of the PROMETE project 2017–2021; the Spanish Ministry of Science and Innovation (PID2019-103886RB-I00\AEI\10.13039\501100011033); and the H2020 program from the European Union (GA no. 654109, 778349, 871115, 101008004 and 101086690)

    Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry

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    Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into the Spanish DILI Registry over a 20-year time period. Methods: Cases were identified, diagnosed and followed prospectively. Clinical features, drug information and outcome data were collected. Results: A total of 843 patients, with a mean age of 54 years (48% females), were enrolled up to 2018. Hepatocellular injury was associated with younger age (adjusted odds ratio [aOR] per year 0.983; 95% CI 0.974-0.991) and lower platelet count (aOR per unit 0.996; 95% CI 0.994-0.998). Anti-infectives were the most common causative drug class (40%). Liver-related mortality was more frequent in patients with hepatocellular damage aged ≥65 years (p = 0.0083) and in patients with underlying liver disease (p = 0.0221). Independent predictors of liver-related death/transplantation included nR-based hepatocellular injury, female sex, higher onset aspartate aminotransferase (AST) and bilirubin values. nR-based hepatocellular injury was not associated with 6-month overall mortality, for which comorbidity burden played a more important role. The prognostic capacity of Hy's law varied between causative agents. Empirical therapy (corticosteroids, ursodeoxycholic acid and MARS) was prescribed to 20% of patients. Drug-induced autoimmune hepatitis patients (26 cases) were mainly females (62%) with hepatocellular damage (92%), who more frequently received immunosuppressive therapy (58%).The present study has been supported by grants of Instituto de Salud Carlos III cofounded by Fondo Europeo de Desarrollo Regional – FEDER (contract numbers: PI19/00883, PI16/01748, PI18/00901, PI18/01804, PI-0285-2016, PI-0274-2016, PI-0310- 2018, PT17/0017/0020) and Agencia Española del Medicamento. CIBERehd and Plataforma ISCIII Ensayos Clinicos are funded by Instituto de Salud Carlos III. MRD holds a Joan Rodes (JR16/ 00015)/Acción B clinicos investigadores (B-0002-2019) and JSC a Rio Hortega (CM17/00243) research contract from ISCIII and Consejería de Salud de Andalucía. The funding sources had no involvement in the study design; in the collection, analysis, and interpretation of data; in the writing of the report or in the de- cision to submit the manuscript for publication

    Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry

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    [Background & Aims] Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into the Spanish DILI Registry over a 20-year time period.[Methods] Cases were identified, diagnosed and followed prospectively. Clinical features, drug information and outcome data were collected.[Results] A total of 843 patients, with a mean age of 54 years (48% females), were enrolled up to 2018. Hepatocellular injury was associated with younger age (adjusted odds ratio [aOR] per year 0.983; 95% CI 0.974–0.991) and lower platelet count (aOR per unit 0.996; 95% CI 0.994–0.998). Anti-infectives were the most common causative drug class (40%). Liver-related mortality was more frequent in patients with hepatocellular damage aged ≥65 years (p = 0.0083) and in patients with underlying liver disease (p = 0.0221). Independent predictors of liver-related death/transplantation included nR-based hepatocellular injury, female sex, higher onset aspartate aminotransferase (AST) and bilirubin values. nR-based hepatocellular injury was not associated with 6-month overall mortality, for which comorbidity burden played a more important role. The prognostic capacity of Hy’s law varied between causative agents. Empirical therapy (corticosteroids, ursodeoxycholic acid and MARS) was prescribed to 20% of patients. Drug-induced autoimmune hepatitis patients (26 cases) were mainly females (62%) with hepatocellular damage (92%), who more frequently received immunosuppressive therapy (58%).[Conclusions] AST elevation at onset is a strong predictor of poor outcome and should be routinely assessed in DILI evaluation. Mortality is higher in older patients with hepatocellular damage and patients with underlying hepatic conditions. The Spanish DILI Registry is a valuable tool in the identification of causative drugs, clinical signatures and prognostic risk factors in DILI and can aid physicians in DILI characterisation and management.[Lay summary] Clinical information on drug-induced liver injury (DILI) collected from enrolled patients in the Spanish DILI Registry can guide physicians in the decision-making process. We have found that older patients with hepatocellular type liver injury and patients with additional liver conditions are at a higher risk of mortality. The type of liver injury, patient sex and analytical values of aspartate aminotransferase and total bilirubin can also help predict clinical outcomes.The present study has been supported by grants of Instituto de Salud Carlos III cofounded by Fondo Europeo de Desarrollo Regional – FEDER (contract numbers: PI19/00883, PI16/01748, PI18/00901, PI18/01804, PI-0285-2016, PI-0274-2016, PI-0310-2018, PT17/0017/0020) and Agencia Española del Medicamento. CIBERehd and Plataforma ISCIII Ensayos Clinicos are funded by Instituto de Salud Carlos III. MRD holds a Joan Rodes (JR16/00015)/Acción B clinicos investigadores (B-0002-2019) and JSC a Rio Hortega (CM17/00243) research contract from ISCIII and Consejería de Salud de Andalucía.Peer reviewe

    5to. Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad. Memoria académica

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    El V Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad, CITIS 2019, realizado del 6 al 8 de febrero de 2019 y organizado por la Universidad Politécnica Salesiana, ofreció a la comunidad académica nacional e internacional una plataforma de comunicación unificada, dirigida a cubrir los problemas teóricos y prácticos de mayor impacto en la sociedad moderna desde la ingeniería. En esta edición, dedicada a los 25 años de vida de la UPS, los ejes temáticos estuvieron relacionados con la aplicación de la ciencia, el desarrollo tecnológico y la innovación en cinco pilares fundamentales de nuestra sociedad: la industria, la movilidad, la sostenibilidad ambiental, la información y las telecomunicaciones. El comité científico estuvo conformado formado por 48 investigadores procedentes de diez países: España, Reino Unido, Italia, Bélgica, México, Venezuela, Colombia, Brasil, Estados Unidos y Ecuador. Fueron recibidas un centenar de contribuciones, de las cuales 39 fueron aprobadas en forma de ponencias y 15 en formato poster. Estas contribuciones fueron presentadas de forma oral ante toda la comunidad académica que se dio cita en el Congreso, quienes desde el aula magna, el auditorio y la sala de usos múltiples de la Universidad Politécnica Salesiana, cumplieron respetuosamente la responsabilidad de representar a toda la sociedad en la revisión, aceptación y validación del conocimiento nuevo que fue presentado en cada exposición por los investigadores. Paralelo a las sesiones técnicas, el Congreso contó con espacios de presentación de posters científicos y cinco workshops en temáticas de vanguardia que cautivaron la atención de nuestros docentes y estudiantes. También en el marco del evento se impartieron un total de ocho conferencias magistrales en temas tan actuales como la gestión del conocimiento en la universidad-ecosistema, los retos y oportunidades de la industria 4.0, los avances de la investigación básica y aplicada en mecatrónica para el estudio de robots de nueva generación, la optimización en ingeniería con técnicas multi-objetivo, el desarrollo de las redes avanzadas en Latinoamérica y los mundos, la contaminación del aire debido al tránsito vehicular, el radón y los riesgos que representa este gas radiactivo para la salud humana, entre otros

    Role of age and comorbidities in mortality of patients with infective endocarditis

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    [Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

    Particle-flow reconstruction and global event description with the CMS detector

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    The CMS apparatus was identified, a few years before the start of the LHC operation at CERN, to feature properties well suited to particle-flow (PF) reconstruction: a highly-segmented tracker, a fine-grained electromagnetic calorimeter, a hermetic hadron calorimeter, a strong magnetic field, and an excellent muon spectrometer. A fully-fledged PF reconstruction algorithm tuned to the CMS detector was therefore developed and has been consistently used in physics analyses for the first time at a hadron collider. For each collision, the comprehensive list of final-state particles identified and reconstructed by the algorithm provides a global event description that leads to unprecedented CMS performance for jet and hadronic tau decay reconstruction, missing transverse momentum determination, and electron and muon identification. This approach also allows particles from pileup interactions to be identified and enables efficient pileup mitigation methods. The data collected by CMS at a centre-of-mass energy of 8 TeV show excellent agreement with the simulation and confirm the superior PF performance at least up to an average of 20 pileup interactions

    Search for heavy resonances decaying to a top quark and a bottom quark in the lepton+jets final state in proton–proton collisions at 13 TeV

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