Proyecto de inversión pública : instalación del servicio de estimulación temprana del niño menor de tres años. Puesto de salud Santa Ana distrito José Leonardo Ortiz. Lambayeque

Contar con un centro de estimulación temprana es una prioridad en los establecimientos de salud del país. Dada la importancia de este proyecto como una alternativa para promover el desarrollo infantil de los menores de tres años de edad del puesto de salud Santa Ana del distrito de José Leonardo Ortiz, Lambayeque, se plantea como objetivo mejorar su nivel de salud y desarrollar la estimulación temprana de manera óptima con la participación de las madres de la comunidad de Santa Ana, en el marco de la reforma de salud y los objetivos del desarrollo sostenible. Así mismo al finalizar el proyecto se habrá logrado fortalecer las competencias del personal de salud, para una adecuada atención de estimulación temprana, así mismo se habrá dotado el equipamiento suficiente en el servicio, como el desarrollo de conocimientos apropiados de las madres sobre el desarrollo infantil temprano, así como fortalecer las capacidades de los pobladores del pueblo joven Santa Ana, para contar con un buen servicio de estimulación temprana y desarrollar practicas adecuadas que constituyan en beneficio del desarrollo integral de los infantes menores de tres años. El desarrollo es un proceso que inicia desde la vida intrauterina de manera ordenada y duradera pasando por la maduración neurológica, comportamental, cognitiva, social y afectiva del niño. Además, se considera un horizonte de duración de 10 años de generación de beneficios, que comprende el tiempo de realización de todas las acciones, la evaluación y seguimiento del proyecto

The CreC regulator of Escherichia coli, a new target for metabolic manipulations

The CreBC (carbon source-responsive) two-component regulation system of Escherichia coli affects a number of functions, including intermediary carbon catabolism. The impacts of different creC mutations (a ΔcreC mutant and a mutant carrying the constitutive creC510 allele) on bacterial physiology were analyzed in glucose cultures under three oxygen availability conditions. Differences in the amounts of extracellular metabolites produced were observed in the null mutant compared to the wild-type strain and the mutant carrying creC510 and shown to be affected by oxygen availability. The ΔcreC strain secreted more formate, succinate, and acetate but less lactate under low aeration. These metabolic changes were associated with differences in AckA and LdhA activities, both of which were affected by CreC. Measurement of the NAD(P)H/NAD(P)+ ratios showed that the creC510 strain had a more reduced intracellular redox state, while the opposite was observed for the ΔcreC mutant, particularly under intermediate oxygen availability conditions, indicating that CreC affects redox balance. The null mutant formed more succinate than the wild-type strain under both low aeration and no aeration. Overexpression of the genes encoding phosphoenolpyruvate carboxylase from E. coli and a NADH-forming formate dehydrogenase from Candida boidinii in the ΔcreC mutant further increased the yield of succinate on glucose. Interestingly, the elimination of ackA and adhE did not significantly improve the production of succinate. The diverse metabolic effects of this regulator on the central biochemical network of E. coli make it a good candidate for metabolic-engineering manipulations to enhance the formation of bioproducts, such as succinate.Fil: Godoy, Manuel Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Nikel, Pablo Ivan. Consejo Superior de Investigaciones Científicas; EspañaFil: Cabrera Gomez, José Gregorio. Unviversidad de San Pablo; BrasilFil: Pettinari, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentin

POTENTIAL GAINS FROM COOPERATION FOR VESSELS AND COUNTRIES

In this paper, we consider a model in which fishing boats or firms share the stock of fish in a fishing ground. The catches made by each firm reduce the stock available for the rest of the firms, which directly affects their profits. We aim to quantify in a static framework the gain in welfare obtained by the firms if they decide to cooperate in order to attain an individually rational efficient outcome. One of the main results is that, both the incentives for the firms to cooperate and the minimum level of catches which permits any gain in welfare decrease as real wage increases. On the other hand, the greater the asymmetry among boats of firms, the more difficult it will be to reach any cooperative agreement.Resource /Energy Economics and Policy,

Plasma ACTH, α-MSH and cortisol variations in the dog during the oestrous cycle in different photoperiods

The hypothalamic-pituitary-adrenal axis (HPA) is a complex system regulated by multiple factors.Sexual dimorphism of this axis has been described in different species under physiological conditions and it hasbeen proposed that sexual hormones could have an effect on it. There are only a few reports about sex-linkedvariations in HPA axis hormones in the dog. Thus, studying the impact of sexual hormones on the HPA axis wouldbroaden the knowledge about its function in this species. Therefore, the objective of this study was to determinewhether there are variations in HPA plasma hormones (ACTH, alfa-melanocyte-stimulating hormone [α-MSH]and cortisol) according to the sex and photoperiod (positive or negative photoperiod were considered when theduration of the light hours of the day was more than 12 or less than 12, respectively) under basal conditions (likeanoestrus) and throughout the oestrous cycle in the female dog. The population under study consisted of 11 intactfemale and 14 intact male dogs. Under basal conditions neither ACTH nor α-MSH concentrations showed differencesbetween sexes and different photoperiods. Cortisol showed greater values in the negative photoperiod thanin the positive, both in females and males (P = 0.03 and P = 0.015, respectively). Throughout the oestrous cycle,all the studied hormones showed variations (P < 0.0001). The greatest concentrations of ACTH were observed atproestrus, while α-MSH and cortisol showed their greatest concentrations at oestrus. The three hormones decreasedin diestrus. ACTH and cortisol concentrations were higher in the negative photoperiod (P = 0.04 and P < 0.0001,respectively), while α-MSH concentrations were higher in the positive photoperiod (P = 0.012). In the group offemales oestradiol and progesterone correlated with ACTH (r = 0.75, P < 0.0001; r = 0.34, P < 0.01, respectively),α-MSH (r = 0.49, P < 0.0001; r = 0.52, P < 0.0001, respectively) and cortisol (r = 0.33, P < 0.01; r = 0.5, P < 0.0001,respectively). These results show that in females, HPA axis hormones vary during the oestrous cycle in relation tooestradiol and progesterone fluctuations. The ACTH, α-MSH and cortisol concentrations also showed differencesbetween photoperiods in females, but only cortisol did so in males. These findings suggest that sexual hormonescould have an effect on the HPA axis. Further research needs to be done to fully understand this interaction andthe mechanisms involved.Fil: Gallelli, María Florencia. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Monachesi, N.. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Miceli, Diego Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Cabrera Battler, M. F.. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Gomez, N. V.. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Meikle, A.. Universidad de Montevideo; UruguayFil: Castillo, V, A.. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; Argentin

A Design Parameter for Reef Beach Profiles—A Methodology Applied to Cadiz, Spain

The southwestern coast of Spain is in a tidal zone (mesotidal) which causes the equilibrium profile to be developed in two different sections: the breakage section and the swash section. These two sections give rise to the typical bi-parabolic profile existing in tidal seas. The existence of areas with reefs/rocks which interrupt the normal development of the typical bi-parabolic profile causes different types of beach profiles. The objective of this article is designing an easy methodology for determining new formulations for the design parameters of the equilibrium profile of beaches with reefs in tidal seas. These formulations are applied on 16 profiles to quantify the error between the real profile data and the modelling results. A comparative analysis is extended to the formulations proposed by other authors, from which it is found that better results are obtained with the new formulations

Medical Telementoring Using an Augmented Reality Transparent Display

Background The goal of this study was to design and implement a novel surgical telementoring system called the System for Telementoring with Augmented Reality (STAR) that uses a virtual transparent display to convey precise locations in the operating field to a trainee surgeon. This system was compared with a conventional system based on a telestrator for surgical instruction. Methods A telementoring system was developed and evaluated in a study which used a 1 × 2 between-subjects design with telementoring system, that is, STAR or conventional, as the independent variable. The participants in the study were 20 premedical or medical students who had no prior experience with telementoring. Each participant completed a task of port placement and a task of abdominal incision under telementoring using either the STAR or the conventional system. The metrics used to test performance when using the system were placement error, number of focus shifts, and time to task completion. Results When compared with the conventional system, participants using STAR completed the 2 tasks with less placement error (45% and 68%) and with fewer focus shifts (86% and 44%), but more slowly (19% for each task). Conclusions Using STAR resulted in decreased annotation placement error, fewer focus shifts, but greater times to task completion. STAR placed virtual annotations directly onto the trainee surgeon's field of view of the operating field by conveying location with great accuracy; this technology helped to avoid shifts in focus, decreased depth perception, and enabled fine-tuning execution of the task to match telementored instruction, but led to greater times to task completion

Comparative Melodic Analysis of A Cappella Flamenco Cantes.

Background in ethnomusicology and music analysis. A cappella singing styles (called cantes in the flamenco jargon) are among the most fundamental song styles within the flamenco repertoire. Until very recently, flamenco singers have been only using oral transmission to learn them. Because of this form of diffusion, melody has become one of the main musical facets to be listened to, remembered, elaborated and spread in flamenco singing styles. Moreover, melody has helped flamenco enthusiasts to remember and identify variants of a particular style or genre. A frequent discussion and unanswered question among flamenco scholars is how to quantify the similarity between two melodies, and how to use this similarity measure to differentiate different styles and variants among performers, and to study the roots and evolution of flamenco styles

Chiral approach to the rho meson in nuclear matter

In this work, the properties of the $\rho$ meson at rest in cold symmetric nuclear matter are studied. We make use of a chiral unitary approach to pion-pion scattering in the vector-isovector channel, calculated from the lowest order Chiral Perturbation Theory ($\chi PT$) lagrangian including explicit resonance fields. Low energy chiral constraints are considered by matching our expressions to those of one loop $\chi PT$. To account for the medium corrections, the $\rho$ couples to $\pi\pi$ pairs which are properly renormalized in the nuclear medium, accounting for both $p-h$ and $\Delta -h$ excitations. The terms where the $\rho$ couples directly to the hadrons in the $p-h$ or $\Delta -h$ excitations are also accounted for. In addition, the $\rho$ is also allowed to couple to $N^{*}(1520)-h$ components.Comment: 30 pages, 20 figures, revised version. Additional sources of the rho selfenergy considered. Some references adde

Unitarized chiral perturbation theory of hadrons

An exposition is made of recent developments using techniques of unitary chiral perturbation theory, $U \chi P T$, which allows one to extend predictions using chiral Lagrangians to higher energies than ordinary chiral perturbation theory, including the region of low lying mesonic and baryonic resonances, some of which are dynamically generated in the approach. Results for meson meson scattering, pion and kaon form factors and meson baryon scattering are shown. Applications are done for nuclear problems showing the results for the kaon and eta selfenergies, phi renormalization in a nuclear medium and $\sigma$ renormalization in the medium, comparing results with recent experiments.Comment: Talk at PANIC2002 Conference, Osaka, October 200