6 research outputs found
éèšă»ć„„ä»
- Author
- Publication venue
- ć ”ćș«èŸČç§ć€§ćŠ
- Publication date
- 01/01/1959
- Field of study
The methylome is subject to genetic and environmental effects. Their impact may depend on sex and age, resulting in sex- and age-related physiological variation and disease susceptibility. Here we estimate the total heritability of DNA methylation levels in whole blood and estimate the variance explained by common single nucleotide polymorphisms at 411,169 sites in 2,603 individuals from twin families, to establish a catalogue of between-individual variation in DNA methylation. Heritability estimates vary across the genome (mean=19%) and interaction analyses reveal thousands of sites with sex-specific heritability as well as sites where the environmental variance increases with age. Integration with previously published data illustrates the impact of genome and environment across the lifespan at methylation sites associated with metabolic traits, smoking and ageing. These findings demonstrate that our catalogue holds valuable information on locations in the genome where methylation variation between people may reflect disease-relevant environmental exposures or genetic variation
Morphologie, Anatomie und Entwicklungsgeschichte der Vegetationsorgane
- Author
- A Braun
- A Engler
- A Engler
- A Grenda
- A Weberbauer
- AG Stokey
- AJ Eames
- C West
- CF Reed
- Contributions to the flora of the Bolivian Andes
- Contributions to the life history of
- CV Morton
- D Meyer
- DH Campbell
- DH Scott
- E Amstutz
- E Asplund
- F Hegelmeier
- F Kienitz-Gerloff
- G Engelmann
- G Iterson
- H Bruchmann
- H Fitting
- H Guttenberg
- H Hofmeister
- H Mohl
- H Solms-Lau-bach
- HK Svenson
- I Manton
- Isoëtes
- Isoëtes lacustris
- Isoëtes Lechleri
- J Liebig
- JB Farmer
- K Goebel
- K MĂ€gdefrau
- K MĂŒller
- L Motelay
- M Hirmer
- More about Isoëtes Lechleri
- NE Pfeiffer
- NeuesĂŒdamerikanische
- O Kruch
- Organographie der Pflanzen
- PB Richter
- R Sadebeck
- R Snow
- R Wettstein
- RW Smith
- TC Palmer
- Tropical American
- U Weber
- W Gothan
- W Rauh
- W Troll
- W Troll
- Weitere Bemerkungen ĂŒber
- WH Lang
- Y Ogura
- Zwei deutsche
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1959
- Field of study
Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions
- Author
- A Clifford
- A Hackshaw
- AA Appleton
- Anne Forhan
- AS Yang
- B Devlin
- Barbara Heude
- BR Joubert
- BS Pedersen
- BT Heijmans
- C Hoyo
- C Nabet
- CJ Petry
- CS Wilhelm-Benartzi
- CV Ananth
- CV Breton
- CV Breton
- D Ershoff
- D Zhang
- DA Armstrong
- DA Armstrong
- Daniel Vaiman
- DC Dolinoy
- DM Messerschmidt
- E Abraham
- E Milne
- E Morales
- EA Houseman
- Ekaterina Bourova-Flin
- EL Rawlins
- EM Price
- Emie Seyve
- ENCODE Project Consortium
- F Costa
- F Court
- F Guida
- Florent Chuffart
- G Mansell
- H Burke
- H Hamada
- H Heyn
- IK Rumrich
- IM Morison
- JD Flom
- Johanna Lepeule
- Jorg Tost
- JR Gibbs
- KD Boehm
- LA Cupul-Uicab
- M Engelhart
- M Suter
- M Suter
- M Toledo-Rodriguez
- M van Iterson
- M Woenckhaus
- MA Kappil
- MA Maccani
- Marie-Aline Charles
- ME Price
- Meriem Benmerad
- MI Bouwland-Both
- MN Hylkema
- N NĂŒsgen
- N Pervjakova
- N Touleimat
- O Koukoura
- P Chu
- P Du
- P Garg
- R Feil
- R Slama
- R Wilson
- Remy Slama
- RK Yuen
- RL Jirtle
- RM Adkins
- S Cnattingius
- S Fa
- S Mary
- Saadi Khochbin
- SE Reese
- SK Murphy
- Sophie Rousseaux
- T Ino
- U Hellmann-Blumberg
- V Karttunen
- Valérie Siroux
- Y Benjamini
- Y Liu
- Y Wei
- Y-A Chen
- Z Ć idĂĄk
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Novel personalized pathway-based metabolomics models reveal key metabolic pathways for breast cancer diagnosis
- Author
- A Brand
- C Denkert
- C Oakman
- C Tiruppathi
- Cancer Genome Atlas N
- CI Rodriguez
- CV Dang
- D Gossai
- D Roy
- DS Wishart
- E Borgan
- E Garcia
- E Jobard
- EE Bolton
- F Zhang
- G Desman
- G Xie
- Guoxiang Xie
- H Blasco
- H Cui
- H Nam
- I Poschke
- I Thiele
- J Krumsiek
- J Krumsiek
- J Shen
- J Wei
- J Xia
- J Xia
- JA Miller
- K Hornik
- KC Marshall
- KK Pasikanti
- L Tenori
- Lana X. Garmire
- M Berg
- M Kanehisa
- M van Iterson
- ML de Leoz
- MN Bucak
- MP Pradhan
- MY Fong
- Nathan E. Lewis
- NE Lewis
- Nicole Chong
- O Fiehn
- R Katz
- S Huang
- SE Singletary
- Sijia Huang
- SJ Jaraj
- SR Johnson
- T Hastie
- T Jewison
- U Guth
- VM Asiago
- W Yang
- Wei Jia
- Y Drier
- Y Fan
- Y Miyagi
- Y Qiu
- Z Cai
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
DNA methylation signatures of educational attainment
- Author
- A Hofman
- A Okbay
- AA Appleton
- AE Poropat
- AF McRae
- AJ Tanaka
- BL Needham
- BR Joubert
- BR Joubert
- BT Heijmans
- C Ling
- C Liu
- C Wang
- CA Miller
- CJ Peter
- CR Marshall
- CS Lai
- CV Dolan
- D McGuinness
- DV Zhernakova
- E Chen
- E Grundberg
- E Hannon
- E Hannon
- E Hannon
- E Kimura
- E Kimura
- EF Tigchelaar
- G Davies
- G Oh
- G Toperoff
- G Willemsen
- GC Patton
- Genome of the Netherlands Consortium.
- GG Song
- H Bruining
- H Li
- H Liu
- H Spiers
- H Yan
- HR Elliott
- IC Weaver
- ID Bross
- J Dongen van
- J Tung
- JL Treur
- JP Fortin
- JV Been
- JY Huang
- K Lenkov
- KA Lillycrop
- KF Dekkers
- KJ Dick
- L Gordon
- L SimĂłn
- LL Lam
- LM Forstbauer
- M Bibikova
- M Bot
- M Esteller
- M Iterson van
- M Schoenmaker
- MA Subramanyam
- ME Hahn
- MJ Aryee
- MJ Bonder
- MS Denison
- N Borghol
- N Snyder-Mackler
- P Rodenas-Cuadrado
- P Tehranifar
- PK Mandal
- PL Jager de
- PO McGowan
- R Gstir
- R Joehanes
- R Karlsson Linnér
- R Kucharski
- R Lister
- RC Richmond
- RJ Pasterkamp
- S Stringhini
- S Zeilinger
- SA Obermann-Borst
- SA Obermann-Borst
- SC Vernes
- SE McCormack
- SH Gage
- SR Beach
- SR Sirin
- T Araki
- T Panni
- T Strenze
- X Gao
- Y Liu
- Ya Chen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Niedere Pflanzen
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- A Bonazzi
- A Caron
- A Caron
- A Cauda
- A Cunningham
- A Demolon
- A Fischer
- A Fuchs
- A Gehring
- A Jahre
- A Janke
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- A Janke
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- W Omelianski
- W Sawyalow
- W.
- W. O. TAUSSON
- W. OMELIANSKI
- WA Albrecht
- WA Feirer
- Wachse
- Waksman
- Wasserleitungsröhren
- WB Aus
- WB Bottomley
- WB Bottomley
- WB Mcdougall
- WC Frazier
- WE Coker
- WE King
- Weiter
- Weiter
- Weiter
- Weiter
- Weitere
- Weitere
- Weiteres
- WH Brierley
- WH Wright
- Whetham
- WO Tausson
- Worden
- WS Sturges
- WS Sturges
- WU KRĂGER
- WU KRĂGER
- WW Ford
- WW KRĂGER
- Y Eine
- Y Emoto
- Y Emoto
- Y Hosaya
- Zersetzung
- Zur Entwicklungsgeschichte einiger Urobakterien usw. Cbl. Bakter. II 68 161
- Ăber
- Ăber
- Ăber
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1931
- Field of study