New line-interactive UPS system with DSP-based active power-line conditioning

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On the constrained KP hierarchy

An explanation for the so-called constrained hierarhies is presented by linking them with the symmetries of the KP hierarchy. While the existence of ordinary symmetries (belonging to the hierarchy) allows one to reduce the KP hierarchy to the KdV hierarchies, the existence of additional symmetries allows to reduce KP to the constrained KP.Comment: 7pp, LaTe

Improved real-time imaging spectrometer

An improved AOTF-based imaging spectrometer that offers several advantages over prior art AOTF imaging spectrometers is presented. The ability to electronically set the bandpass wavelength provides observational flexibility. Various improvements in optical architecture provide simplified magnification variability, improved image resolution and light throughput efficiency and reduced sensitivity to ambient light. Two embodiments of the invention are: (1) operation in the visible/near-infrared domain of wavelength range 0.48 to 0.76 microns; and (2) infrared configuration which operates in the wavelength range of 1.2 to 2.5 microns

FAM129B, an antioxidative protein, reduces chemosensitivity by competing with Nrf2 for Keap1 binding.

BackgroundThe transcription factor Nrf2 is a master regulator of antioxidant response. While Nrf2 activation may counter increasing oxidative stress in aging, its activation in cancer can promote cancer progression and metastasis, and confer resistance to chemotherapy and radiotherapy. Thus, Nrf2 has been considered as a key pharmacological target. Unfortunately, there are no specific Nrf2 inhibitors for therapeutic application. Moreover, high Nrf2 activity in many tumors without Keap1 or Nrf2 mutations suggests that alternative mechanisms of Nrf2 regulation exist.MethodsInteraction of FAM129B with Keap1 is demonstrated by immunofluorescence, colocalization, co-immunoprecipitation and mammalian two-hybrid assay. Antioxidative function of FAM129B is analyzed by measuring ROS levels with DCF/flow cytometry, Nrf2 activation using luciferase reporter assay and determination of downstream gene expression by qPCR and wester blotting. Impact of FAM129B on in vivo chemosensitivity is examined in mice bearing breast and colon cancer xenografts. The clinical relevance of FAM129B is assessed by qPCR in breast cancer samples and data mining of publicly available databases.FindingsWe have demonstrated that FAM129B in cancer promotes Nrf2 activity by reducing its ubiquitination through competition with Nrf2 for Keap1 binding via its DLG and ETGE motifs. In addition, FAM129B reduces chemosensitivity by augmenting Nrf2 antioxidative signaling and confers poor prognosis in breast and lung cancer.InterpretationThese findings demonstrate the important role of FAM129B in Nrf2 activation and antioxidative response, and identify FMA129B as a potential therapeutic target. FUND: The Chang Gung Medical Foundation (Taiwan) and the Ministry of Science and Technology (Taiwan)

Use of FBG optical sensors for structural health monitoring: Practical application

This paper describes the development of FBG Optical sensors for their practical application on structural health monitoring. The sensors were installed on the Tsing Ma Bridge for a trial run. The results using FBG sensors were in excellent agreement with those acquired by the bridge WASHMS

XOR multiplexing technique for nanocomputers

In emerging nanotechnologies, due to the manufacturing process, a significant percentage of components may be faulty. In order to make systems based on unreliable nano-scale components reliable, it is necessary to design fault-tolerant architectures. This paper presents a novel fault-tolerant technique for nanocomputers, namely the XOR multiplexing technique. This hardware redundancy technique is based on a numerous duplication of faulty components. We analyze the error distributions of the XOR multiplexing unit and the error distributions of multiple stages of the XOR multiplexing system, then compare them to the NAND multiplexing unit and the NAND multiplexing multiple stages system, respectively. The simulation results show that XOR multiplexing is more reliable than NAND multiplexing. Bifurcation theory is used to analyze the fault-tolerant ability of the system and the results show that XOR multiplexing technique has a high fault-tolerant ability. Similarly to the NAND multiplexing technique, this fault-tolerant technique is a potentially effective fault tolerant technique for future nanoelectronics

On Goldstone bosons decoupling from high-lying hadrons

In this paper, we discuss a decoupling of the Goldstone bosons from highly excited hadrons in relation to the restoration of chiral symmetry in such hadrons. We use a generalised Nambu-Jona-Lasinio model with the interaction between quarks in the form of an instantaneous Lorentz-vector confining potential. This model is known to provide spontaneous breaking of chiral symmetry in the vacuum via the standard selfenergy loops for valence quarks. For highly excited hadrons, where the typical momentum of valence quarks is large, the loop contributions represent only a small correction to the chiral-invariant classical contributions and asymptotically vanish. Consequently the chiral symmetry violating Lorentz-scalar dynamical mass of quarks vanishes. Then the conservation of the axial vector current in the chiral limit requires, via the Goldberger-Treiman relation, that the valence quarks decouple from the Goldstone boson. As a consequence, the whole hadron decouples from the Goldstone boson as well, which implies that its axial constant also vanishes.Comment: RevTeX4, 21 pages, 5 Postscript figures, uses epsfig.sty, new chapter with numerical estimates added, to appear in Phys.Rev.

Chiral symmetry restoration in excited hadrons, quantum fluctuations, and quasiclassics

In this paper, we discuss the transition to the semiclassical regime in excited hadrons, and consequently, the restoration of chiral symmetry for these states. We use a generalised Nambu-Jona-Lasinio model with the interaction between quarks in the form of the instantaneous Lorentz-vector confining potential. This model is known to provide spontaneous breaking of chiral symmetry in the vacuum via the standard selfenergy loops for valence quarks. It has been shown recently that the effective single-quark potential is of the Lorentz-scalar nature, for the low-lying hadrons, while, for the high-lying states, it becomes a pure Lorentz vector and hence the model exhibits the restoration of chiral symmetry. We demonstrate explicitly the quantum nature of chiral symmetry breaking, the absence of chiral symmetry breaking in the classical limit as well as the transition to the semiclassical regime for excited states, where the effect of chiral symmetry breaking becomes only a small correction to the classical contributions.Comment: RevTeX4, 20 pages, 4 Postscript figures, uses epsfig.sty, typos correcte

Charmless Three-body Decays of B Mesons

Charmless 3-body decays of B mesons are studied in the framework of the factorization approach. The nonresonant contributions arising from $B\to P_1P_2$ transitions are evaluated using heavy meson chiral perturbation theory (HMChPT). The momentum dependence of nonresonant amplitudes is assumed to be in the exponential form e^{-\alpha_{NR}} p_B\cdot(p_i+p_j)} so that the HMChPT results are recovered in the soft meson limit $p_i, p_j\to 0$. In addition, we have identified another large source of the nonresonant signal in the matrix elements of scalar densities, e.g. $$, which can be constrained from the decay $\bar B^0\to K_SK_SK_S$ or $B^-\to K^-K_SK_S$. The intermediate vector meson contributions to 3-body decays are identified through the vector current, while the scalar meson resonances are mainly associated with the scalar density. Their effects are described in terms of the Breit-Wigner formalism. Our main results are: (i) All KKK modes are dominated by the nonresonant background. The predicted branching ratios of $K^+K^-K_{S(L)}$, $K^+K^-K^-$ and $K^-K_SK_S$ modes are consistent with the data within errors. (ii) Although the penguin-dominated $B^0\to K^+K^-K_{S}$ decay is subject to a potentially significant tree pollution, its effective $\sin 2\beta$ is very similar to that of the $K_SK_SK_S$ mode. However, direct CP asymmetry of the former, being of order -4%, is more prominent than the latter. (iii) For $B\to K\pi\pi$ decays, we found sizable nonresonant contributions in $K^-\pi^+\pi^-$ and $\bar K^0\pi^+\pi^-$ modes, in agreement with the Belle measurements but larger than the BaBar result.Comment: 39 pages, 2 figures, version to appear in PR

Neural plasticity in common forms of chronic headaches

Headaches are universal experiences and among the most common disorders. While headache may be physiological in the acute setting, it can become a pathological and persistent condition.The mechanisms underlying the transition from episodic to chronic pain have been the subject of intense study. Using physiological and imaging methods, researchers have identified a number of different forms of neural plasticity associated with migraine and other headaches, including peripheral and central sensitization, and alterations in the endogenous mechanisms of pain modulation. While these changes have been proposed to contribute to headache and pain chronification, some findings are likely the results of repetitive noxious stimulation, such as atrophy of brain areas involved in pain perception and modulation. In this review, we provide a narrative overview of recent advances on the neuroimaging, electrophysiological and genetic aspects of neural plasticity associated with the most common forms of chronic headaches, including migraine, cluster headache, tension-type headache, and medication overuse headache