48 research outputs found
Physics of Solar Prominences: II - Magnetic Structure and Dynamics
Observations and models of solar prominences are reviewed. We focus on
non-eruptive prominences, and describe recent progress in four areas of
prominence research: (1) magnetic structure deduced from observations and
models, (2) the dynamics of prominence plasmas (formation and flows), (3)
Magneto-hydrodynamic (MHD) waves in prominences and (4) the formation and
large-scale patterns of the filament channels in which prominences are located.
Finally, several outstanding issues in prominence research are discussed, along
with observations and models required to resolve them.Comment: 75 pages, 31 pictures, review pape
Paricle identification at VAMOS++ with machine learning techniques
Multi-nucleon transfer reaction between 136Xe beam and 198Pt target was performed using the VAMOS++ spectrometer at GANIL to study the structure of n-rich nuclei around N=126. Unambiguous charge state identification was obtained by combining two supervised machine learning methods, deep neural network (DNN) and positional correction using a gradient-boosting decision tree (GBDT). The new method reduced the complexity of the kinetic energy calibration and outperformed the conventional method improving the charge state resolution by 8%
Precision Measurement of the Proton Flux in Primary Cosmic Rays from Rigidity 1 GV to 1.8 TV with the Alpha Magnetic Spectrometer on the International Space Station
A precise measurement of the proton flux in primary cosmic rays with rigidity (momentum/charge) from 1 GV to 1.8 TV is presented based on 300 million events. Knowledge of the rigidity dependence of the proton flux is important in understanding the origin, acceleration, and propagation of cosmic rays. We present the detailed variation with rigidity of the flux spectral index for the first time. The spectral index progressively hardens at high rigidities.</p
An immunohistochemical study of the expression of cell-cycle-regulated proteins p53, cyclin D1, RB, p27, Ki67 and MSH2 in gallbladder carcinoma and its precursor lesions
Gallbladder carcinomas are rare but highly
lethal neoplasms. We examined the expression of five
cell-cycle-related molecules (p53, RB, cyclin D1, p27,
Ki-67), and MSH2, in 46 carcinomas, 14 adenomas, 15
low-grade dysplasias, 9 intestinal metaplasias and 20
normal gallbladder epithelia. The expression of these
molecules was altered in gallbladder carcinomas and
adenomas. In gallbladder carcinomas we observed
increased expression of p53, cyclin D1, Ki-67, and
MSH2 together with decreased expression of RB and
p27 protein. Aberrant expression of cyclin D1 and
reduced expression of RB were noted in adenomas, and
expression of cyclin D1 was elevated in low-grade
dysplasias. However, there was no change in the levels
of these cell-cycle molecules in metaplasia. Expression
of p53, p27, Ki-67, and MSH2 was correlated with
clinical stage (P<0.05) and there was also a correlation
between the expression of Ki-67 and MSH-2 and patient
age (P<0.05). These results suggest that altered
expression of cell-cycle molecules p53, cyclin D1, RB,
p27, and of MSH-2 is involved in the progression of
gallbladder carcinomas
Detection by In-situ Hybridization of Pasteurella multocida Toxin (toxA) Gene in the Lungs of Naturally Infected Pigs
In-situ hybridization with a non-radioactive digoxigenin-labelled probe was used to detect the Pasteurella multocida toxin (PMT) gene in tissue sections of pneumonic lung from pigs naturally infected with toxigenic P. multocida. The morphology of host cells was preserved despite the relatively high temperature used in the incubation procedure. Pulmonary abscessation was observed in 13 pigs naturally infected with toxigenic P. multocida type A (three pigs) or D (10 pigs). In these 13 pigs a strong hybridization signal for PMT DNA was detected, mainly in degenerate leucocytes in abscesses. Occasionally, PMT DNA was detected in degenerate neutrophils and macrophages in alveolar spaces. Detection of hybridization signals for PMT DNA would seem to be a potential indicator of the production of PMT. The study suggested that PMT plays an important role in pulmonary abscessation caused by P. multocida.This research was supported by the contract research funds of the Research Institute for Veterinary Science (RIVS) from the College of Veterinary Medicine, Seoul National University, and the Brain Korea 21 Program for Veterinary Science, Republic of Korea