Ponseti Method: Does Age at the Beginning of Treatment Make a Difference?

The Ponseti method is reportedly effective for treating clubfoot in children up to 9 years of age. However, whether age at the beginning of treatment influences the rate of successful correction and the rate of relapse is unknown. We therefore retrospectively reviewed 68 consecutive children with 102 idiopathic clubfeet treated by the Ponseti technique in four Portuguese hospitals. We followed patients a minimum of 30 months (mean, 41.4 months; range, 30–61 months). The patients were divided into two groups according to their age at the beginning of treatment; Group I was younger than 6 months and Group II was older than 6 months. All feet(100%) were initially corrected and no feet required extensive surgery regardless of age at the beginning of treatment. There were no differences between Groups I and II in the number of casts, tenotomies, success in terms of rate of initial correction, rate of recurrence, and rate of tibialis anterior transference. The rate of the Ponseti method in avoiding extensive surgery was 100% in Groups I and II; relapses occurred in 8% of the feet in younger and older children. Level of Evidence: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence

Comparison of 30 THz impulsive burst time development to microwaves, H-alpha, EUV, and GOES soft X-rays

The recent discovery of impulsive solar burst emission in the 30 THz band is raising new interpretation challenges. One event associated with a GOES M2 class flare has been observed simultaneously in microwaves, H-alpha, EUV, and soft X-ray bands. Although these new observations confirm some features found in the two prior known events, they exhibit time profile structure discrepancies between 30 THz, microwaves, and hard X-rays (as inferred from the Neupert effect). These results suggest a more complex relationship between 30 THz emission and radiation produced at other wavelength ranges. The multiple frequency emissions in the impulsive phase are likely to be produced at a common flaring site lower in the chromosphere. The 30 THz burst emission may be either part of a nonthermal radiation mechanism or due to the rapid thermal response to a beam of high-energy particles bombarding the dense solar atmosphere.Comment: accepted to Astronomy and Astrophysic

Production system of organic orange and its implications: Study in the SOS site Agroecological, Northeast of Pará

The organic production of produce in Brazil has been increasing very year due higher demand for more health food, and many farmers are migrating to these concept of food production. Therefore, the aim of this study is to understand the philosophic concept, as well as doing a description and analyzing the implications of the production system of organic orange. The research was done at Sítio SOS Agroecológico, localized in the city of CapitãoPoço, northeast of Pará. The qualitative exploratory research was done with the owner of the area, who is also a producer of organic orange, through, mainly, visits, semi structured surveys, transect walks in the area, and photographic records. The production of the site is considered adequate; their main market are organic fairs and big supermarkets; however, price and logistic are the main obstacles, besides the certification, where in Brazil is still an onerous process. The production system of Sitio SOS shows certain similarities with the concept of biologic and natural agriculture since both systems goals are the reduction of the rural producer costs, the use of alternative products and/or natural available on the property

Bright 30 THz Impulsive Solar Bursts

Impulsive 30 THz continuum bursts have been recently observed in solar flares, utilizing small telescopes with a unique and relatively simple optical setup concept. The most intense burst was observed together with a GOES X2 class event on October 27, 2014, also detected at two sub-THz frequencies, RHESSI X-rays and SDO/HMI and EUV. It exhibits strikingly good correlation in time and in space with white light flare emission. It is likely that this association may prove to be very common. All three 30 THz events recently observed exhibited intense fluxes in the range of 104 solar flux units, considerably larger than those measured for the same events at microwave and sub-mm wavelengths. The 30 THz burst emission might be part of the same spectral burst component found at sub-THz frequencies. The 30 THz solar bursts open a promising new window for the study of flares at their originComment: 11 pages, 4 Figures J. Geophys. Res - Space Physics, accepted, May 21, 201

Study of physiological maturity of melon seeds by enzymatic changes.

Thus, this study aimed to determine physiological and enzymatic changes during the maturation process of melon seeds of the cultivar BRS Anton, obtained from fruits at different maturation stages and subjected to post-harvest storage, by the action of total proteins and the enzymes catalase, peroxidase, and superoxide dismutase. Melon fruits were grown in a greenhouse at Embrapa Vegetables and harvested at five different times: 30, 45, 60, 75, and 90 days after anthesis (DAA)

Variants at the ASIP locus contribute to coat color darkening in Nellore cattle

Background: Nellore cattle (Bos indicus) are well-known for their adaptation to warm and humid environments. Hair length and coat color may impact heat tolerance. The Nellore breed has been strongly selected for white coat, but bulls generally exhibit darker hair ranging from light grey to black on the head, neck, hump, and knees. Given the potential contribution of coat color variation to the adaptation of cattle populations to tropical and sub-tropical environments, our aim was to map positional and functional candidate genetic variants associated with darkness of hair coat (DHC) in Nellore bulls. Results: We performed a genome-wide association study (GWAS) for DHC using data from 432 Nellore bulls that were genotyped for more than 777 k single nucleotide polymorphism (SNP) markers. A single major association signal was detected in the vicinity of the agouti signaling protein gene (ASIP). The analysis of whole-genome sequence (WGS) data from 21 bulls revealed functional variants that are associated with DHC, including a structural rearrangement involving ASIP (ASIP-SV1). We further characterized this structural variant using Oxford Nanopore sequencing data from 13 Australian Brahman heifers, which share ancestry with Nellore cattle; we found that this variant originates from a 1155-bp deletion followed by an insertion of a transposable element of more than 150 bp that may impact the recruitment of ASIP non-coding exons. Conclusions: Our results indicate that the variant ASIP sequence causes darker coat pigmentation on specific parts of the body, most likely through a decreased expression of ASIP and consequently an increased production of eumelanin