Weighing the black holes in ultraluminous X-ray sources through timing

We describe a new method to estimate the mass of black holes in Ultraluminous X-ray Sources (ULXs). The method is based on the recently discovered ``variability plane'', populated by Galactic stellar-mass black-hole candidates (BHCs) and supermassive active galactic nuclei (AGNs), in the parameter space defined by the black-hole mass, accretion rate and characteristic frequency. We apply this method to the two ULXs from which low-frequency quasi-periodic oscillations have been discovered, M82 X-1 and NGC 5408 X-1. For both sources we obtain a black-hole mass in the range 100~1300 Msun, thus providing evidence for these two sources to host an intermediate-mass black hole.Comment: 5 pages, 2 figures, Accepted by MNRA

The ABC of low-frequency quasi-periodic oscillations in Black-Hole Candidates: analogies with Z-sources

Three main types of low-frequency quasi-periodic oscillations (LFQPOs) have been observed in Black Hole Candidates. We re-analyzed RXTE data of the bright systems XTE J1859+226, XTE J1550-564 and GX 339-4, which show all three of them. We review the main properties of these LFQPOs and show that they follow a well-defined correlation in a fractional rms vs. softness diagram. We show that the frequency behavior through this correlation presents clear analogies with that of Horizontal-, Normal- and Flaring-Branch Oscillations in Z sources, with the inverse of the fractional rms being the equivalent of the curvilinear coordinate Sz through the Z track.Comment: 5 pages, 4 figures, accepted by ApJ, uses emulateap

Effect of sterilization treatment on the corrosion behavior of NiTi endodontic instruments

This study investigates the influence of the sterilization treatment conducted at 50 °C in 5% sodium hypochlorite solution (NaClO) on the corrosion behavior of endodontic instruments made of NiTi alloy (GT Rotary and K3) and stainless steel (K File) by measuring potentiodynamic polarization curves in the same environment at 37°C. For the sake of comparison, the electrochemical characterization was also carried out on endodontic instruments that were not sterilized. The characterization of the sample surface after the electrochemical tests were carried out by means of scanning electron microscopy (SEM) coupled with X-ray energy dispersive spectroscopy (EDX). There was no significant influence of the sterilization treatment on the corrosion behavior of K File and GT Rotary endodontic instruments. On the contrary, a negative influence of the sterilization treatment on the corrosion resistance of K3 endodontic instruments was observed, and the effect appears to be more dramatic for longer treatment periods

Evolution of the bursting-layer wave during a Type 1 X-ray burst

In a popular scenario due to Heyl, quasi periodic oscillations (QPOs) which are seen during type 1 X-ray bursts are produced by giant travelling waves in neutron-star oceans. Piro and Bildsten have proposed that during the burst cooling the wave in the bursting layer may convert into a deep crustal interface wave, which would cut off the visible QPOs. This cut-off would help explain the magnitude of the QPO frequency drift, which is otherwise overpredicted by a factor of several in Heyl's scenario. In this paper, we study the coupling between the bursting layer and the deep ocean. The coupling turns out to be weak and only a small fraction of the surface-wave energy gets transferred to that of the crustal-interface wave during the burst. Thus the crustal-interface wave plays no dynamical role during the burst, and no early QPO cut-off should occur.Comment: 8 pages, submitted to MNRA

Rate-Control or Rhythm-Contol: Where do we stand?

Atrial fibrillation is the most common sustained rhythm disturbance and its prevalence is increasing worldwide due to the progressive aging of the population. Current guidelines clearly depict the gold standard management of acute symptomatic atrial fibrillation but the best-long term approach for first or recurrent atrial fibrillation is still debated with regard to quality of life, risk of new hospitalizations, and possible disabling complications, such as thromboembolic stroke, major bleeds and death. Some authors propose that regaining sinus rhythm in all cases, thus re-establishing a physiologic cardiac function not requiring a prolonged antithrombotic therapy, avoids the threat of intracranial or extracranial haemorrhages due to Vitamin K antagonists or aspirin. On the contrary, advocates of a rate control approach with an accurate antithrombotic prophylaxis propose that such a strategy may avoid the risk of cardiovascular and non cardiovascular side effects related to antiarrhythmic drugs. This review aims to explore the state of our knowledge in order to summarize evidences and issues that need to be furthermore clarified

A Bayesian analysis of mixed survival models

International audienc

A SCORM Thin Client Architecture for e-learning Systems based on Web Services

In this paper we propose an architecture of e-learning systems characterized by the use of Web services and a suitable middleware component. These technical infrastructures allow us to extend the system with new services as well as to integrate and reuse heterogeneous software e-learning components. Moreover, they let us better support the "anytime and anywhere " learning paradigm. As a matter of fact, the proposal provides an implementation of the run-time environment suggested in the sharable content object reference model (SCORM) to trace learning processes, which is also suitable for mobile learning

Ionic liquid crystals based on viologen dimers: tuning the mesomorphism by varying the conformational freedom of the ionic layer

We investigated the liquid crystal behaviour of newly synthesised bistriflimide salts of symmetric viologen dimers. A smectic A phase was observed for intermediate spacer lengths and for relatively long lateral alkyl chains. The systems were characterised by thermal analysis, polarised optical microscopy, X-ray scattering and solid-state NMR. An intermediate ordered smectic phase was also exhibited by the compounds (except for systems with very short lateral chains) consisting of molten layers of alkyl chains and partially ordered ionic layers. These results, relating to the mesomorphic behaviour of viologen salts, are qualitatively compared to those of the more common imidazolium salts, highlighting the importance of the conformational degrees of freedom of the anions and of the cationic core. It appears that fine tuning of the conformational degrees of freedom of the ionic layer is an important component of mesophase stabilisation

Non Celiac Gluten Sensitivity and Diagnostic Challenges

Non-celiac gluten sensitivity (NCGS), also referred to as non-celiac wheat sensitivity (NCWS), is a clinical syndrome characterized by both intestinal and extra-intestinal symptoms responsive to the withdrawal of gluten-containing food from the diet. The aim of this review is to summarize recent advances in research and provide a brief overview of the history of the condition for the benefit of professionals working in gastroenterology. Academic databases such as PubMed and Google Scholar were searched using key words such as ”non-celiac gluten sensitivity”, “gluten related disorders”, and the studies outlined in reference page were selected and analysed. Most of the analysed studiers agree that NCGS would need to be diagnosed only after exclusion of celiac disease and wheat allergy, and that a reliable serological marker is not available presently. The mechanisms causing symptoms in NCGS after gluten ingestion are largely unknown, but recent advances have begun to offer novel insights. The estimated prevalence of NCGS, at present, varies between 0.6 and 6%. There is an overlap between irritable bowel syndrome and NCGS with regard to the similarity of gastrointestinal symptoms. The histologic characteristics of NCGS are still under investigation, ranging from normal histology to slight increase in the number of T lymphocytes in the superficial epithelium of villi. Positive response to gluten free diet for a limited period (e.g., 6 weeks), followed by the reappearance of symptoms after gluten challenge appears, at this moment, to be the best approach for confirming diagnosis. The Salerno expert criteria may help to diagnose NCGS accurately in particular for research purposes but it has limited applicability in clinical practice