73 research outputs found
Background subtraction with Dirichlet processes
Abstract. Background subtraction is an important first step for video analysis, where it is used to discover the objects of interest for fur-ther processing. Such an algorithm often consists of a background model and a regularisation scheme. The background model determines a per-pixel measure of if a pixel belongs to the background or the foreground, whilst the regularisation brings in information from adjacent pixels. A new method is presented that uses a Dirichlet process Gaussian mixture model to estimate a per-pixel background distribution, which is followed by probabilistic regularisation. Key advantages include inferring the per-pixel mode count, such that it accurately models dynamic backgrounds, and that it updates its model continuously in a principled way.
Whole-genome sequencing reveals host factors underlying critical COVID-19
Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
Efficient incorporation of motionless foreground objects for adaptive background segmentation
Conference on Articulated Motion and Deformable Objects (AMDO), 2006, Andratx (Spain)In this paper, we want to exploit the knowledge obtained from those detected objects which are incorporated into the background model since they cease their movement. These motionless foreground objects should be handled in security domains such as video surveillance. This paper uses an adaptive background modelling algorithm for moving-object detection. Those detected objects which present no motion are identified and added into the background model, so that they will be part of the new background. Such motionless agents are included for further appearance analysis and agent categorization.This work was supported by the project 'Integration of robust perception, learning, and navigation systems in mobile robotics' (J-0929).Peer Reviewe
A Novel Broadband Ultrasonic Location System
Indoor ultrasonic location systems provide ne-grained position data to ubiquitous computing applications. However, the ultrasonic location systems previously developed utilize narrowband transducers, and thus perform poorly in the presence of noise and are constrained by the fact that signal collisions must be avoided. In this paper, we present a novel ultrasonic location system which utilizes broadband transducers. We describe the transmitter and receiver hardware, and characterize the ultrasonic channel bandwidth. The system has been deployed as a polled, centralized location system in an of ce. Test results demonstrate that the system can function in high levels of environmental noise, and that it has the capability for higher update rates than previous ultrasonic location systems
Robust analysis of silhouettes by morphological size distributions
peer reviewedWe address the topic of real-time analysis and recognition of silhouettes. The method that we propose first produces object features obtained by a new type of morphological operators, which can be seen as an extension of existing granulometric filters, and then insert them into a tailored classification scheme. Intuitively, given a binary segmented image, our operator produces the set of all the largest rectangles that can be wedged inside any connected component of the image. The latter are obtained by a standard background subtraction technique and morphological filtering. To classify connected components into one of the known object categories, the rectangles of a connected component are submitted to a machine learning algorithm called EXtremely RAndomized trees (Extra-trees). The machine learning algorithm is fed with a static database of silhouettes that contains both positive and negative instances. The whole process, including image processing and rectangle classification, is carried out in real-time. Finally we evaluate our approach on one of today's hot topics: the detection of human silhouettes. We discuss experimental results and show that our method is stable and computationally effective. Therefore, we assess that algorithms like ours introduce new ways for the detection of humans in video sequences
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