151 research outputs found

    Improving professional observers’ veracity judgments by tactical interviewing

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    Understanding whether a person of interest is being truthful during an investigative interview is a constant challenge and is of concern to numerous criminal justice professionals, most of whom are not involved in conducting the interview itself. Here, we investigated police observers’ veracity detection performance having viewed interviews with truthtellers and deceivers using either the tactical use of evidence (TUE), strategic use of evidence (SUE) or a control technique. Thirty serving police officers participated as post-interview observers and each viewed 12 interviews in a counterbalanced order. After each interview, the officer made a veracity judgement. Overall, untrained police observers were significantly more accurate (68%) when making veracity judgements post-TUE interviews, whereas for both SUE and control performance was around chance (51% and 48%, respectively). Veracity performance for liars and truthtellers revealed a similar pattern of results (67% liars; 70% truthtellers) in the TUE condition. These results lend further support to the psychological literature highlighting the importance of how and when to reveal evidence or any other relevant event information during an investigative interview for ‘outing’ deceivers as well as allowing truthtellers early opportunities to demonstrate their innocence

    Threshold Behavior Of (gaal)as-gaas Lasers At Low Temperatures

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    The temperature dependence of the threshold current, differential quantum efficiency, and internal loss have been measured in the temperature range 10-293°K. The threshold current increases relatively slowly with temperature above 100°K and is independent of the impurity concentration. Theoretical calculation shows that this behavior is to be expected for a band-to-band transition that follows k selection. The threshold behavior at low temperatures (≤ 80°K) depends strongly on the type and concentration of the impurity. The relatively fast decrease in threshold below 100°K shows saturation for an active layer with n-type impurities or with high-concentration p-type impurities. The saturation is attributed to the carrier diffusion length becoming smaller than the active-layer thickness. The internal differential quantum efficiency is near unity and is independent of temperature. The internal loss, however, decreases with temperature due to reduction in free-carrier absorption.491293

    Modern pollution signals in sediments from Windermere, NW England, determined by micro-XRF and lead isotope analysis

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    High resolution geochemical (Itrax micro-XRF and wavelength dispersive XRF) data, radiochronology (210Pb and 137Cs analyses) and ultra-high precision double-spike lead isotope measurements from lacustrine sediment cores are used in combination with historical research of former mining landscapes to investigate modern pollution signals in sediments from Windermere, the largest lake in the English Lake District. The sediment record suggests that while most element concentrations have been stable, there has been a significant increase since the 1930s in lead, zinc and copper concentrations. Double-spike lead isotope measurements reveal a mixture of natural lead, and three major contributory sources of anthropogenic (industrial) lead, comprising gasoline lead, coal combustion lead (from coal-fired steam ships) and lead derived from Carboniferous Pb–Zn mineralisation (mining activities). A number of up-system sediment traps have limited the amount of mining related heavy metals entering Windermere, and as a result, periods of metal workings do not correlate with peaks in heavy metals. Increases could also be due to flood-induced metal inwash or weathering of bedrock in the catchment. Application of these non-destructive and high precision analytical techniques provides new insights into the pollutant depositional history of Windermere

    A 500 year sediment lake record of anthropogenic and natural inputs to Windermere (English Lake District) using double-spike lead isotopes, radiochronology, and sediment microanalysis

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    A high-resolution record of pollution is preserved in recent sediments from Windermere, the largest lake in the English Lake District. Data derived from X-ray core scanning (validated against wavelength dispersive X-ray fluorescence), radiochronological techniques (210Pb and 137Cs) and ultrahigh precision, double-spike mass spectrometry for lead isotopes are combined to decipher the anthropogenic inputs to the lake. The sediment record suggests that while most element concentrations have been stable, there has been a significant increase in lead, zinc, and copper concentrations since the 1930s. Lead isotope down-core variations identify three major contributory sources of anthropogenic (industrial) lead, comprising gasoline lead, coal combustion lead (most likely source is coal-fired steam ships), and lead derived from Carboniferous Pb–Zn mineralization (mining activities). Periods of metal workings do not correlate with peaks in heavy metals due to the trapping efficiency of up-system lakes in the catchment. Heavy metal increases could be due to flood-induced metal inwash after the cessation of mining and the weathering of bedrock in the catchment. The combination of sediment analysis techniques used provides new insights into the pollutant depositional history of Windermere and could be similarly applied to other lake systems to determine the timing and scale of anthropogenic inputs

    Geometry and slip rate of the Aigion fault, a young normal fault system in the western Gulf of Corinth

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    The Aigion fault is one of the youngest major normal faults in the Gulf of Corinth, Greece, with an immature displacement profile. Based on geometry, slip rate and comparison with regional faults, we estimate the fault system length at ~10 km. We find the slip rate of the fault system is ~3.5 ± 1 mm/yr decreasing to ~2.5 ± 0.7 mm/yr close to its eastern tip. Complex fault geometry and displacement profiles on the shelf east of Aigion are consistent with the latter as the eastern tip location. Analysis of slip on this fault system and the established fault to the south (Western Eliki Fault) suggests that slip was transferred rapidly but not homogeneously between the two faults during the period of contemporaneous activity. Together with a lack of evidence of lateral propagation at the eastern fault tip in the last 10–13 k.y., we suggest that the fault developed and established its current length rapidly, within its 200–300 k.y. history. These results contribute to our understanding of the process of northward fault migration into the rift and the development of new normal faults

    Monitoring Chemical Pollution in Europe’s Seas: Programmes, practices and priorities for research

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    This report has been produced by the Marine Board Working Group on Existing and Emerging Chemical Pollutants (WGPOL) first convened in 2008 and tasked to examine the assessment and monitoring of existing and emerging chemicals in the European marine and coastal environment. The Working Group considered (i) existing monitoring/assessment frameworks; (ii) current monitoring practices; and (iii) new and emerging chemicals of concern and the mechanisms used to include them in current monitoring programmes. The primary conclusions and recommendations of this position paper are: 1. Fully implement state of the art environmental risk assessment procedures (combining exposure and effect assessment) to evaluate the full impact of chemical substances on the different compartments of coastal and open sea systems. 2. Further improve the coordination, cooperation and harmonization between existing monitoring efforts and those under development, to avoid duplication of effort, loss of expertise and a reduced willingness to fulfil the obligations towards regional conventions. 3. Ensure that the development and implementation of monitoring programmes for the assessment of chemicals in marine and coastal environment are based on a science-based and dynamic process. 4. Apply more resources targeted at developing appropriate approaches, tools and practices (education and training) to improve the acquisition and management of monitoring data. In addition to the above main recommendations, two further recommendations have been identified on the basis of two specific case studies which form part of this paper and which focus on the release, effects and monitoring of (i) hydrophobic and insoluble chemicals in the marine environment from merchant shipping; and (ii) chemicals released by the offshore oil-industry in the North Sea. These case studies highlighted the need to: 5. Develop a consistent, pan-European or regional (legal) framework/regulation which covers the activities of the oil and gas industry at sea. At the same time, more information and research is needed on the release and the effects of chemicals arising from offshore oil and gas activities. 6. Develop and apply state-of-the-art environmental risk assessment procedures (combining exposure and effect assessments, including on human health) to evaluate the impact of noxious liquid substances listed under MARPOL Annex II on the different compartments in coastal and open sea ecosystems

    Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

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    Background:Some individuals living with obesity may be relatively metabolically healthy, whilst others suffer from multiple conditions that may be linked to adverse metabolic effects or other factors. The extent to which the adverse metabolic component of obesity contributes to disease compared to the non-metabolic components is often uncertain. We aimed to use Mendelian randomisation (MR) and specific genetic variants to separately test the causal roles of higher adiposity with and without its adverse metabolic effects on diseases.Methods:We selected 37 chronic diseases associated with obesity and genetic variants associated with different aspects of excess weight. These genetic variants included those associated with metabolically ‘favourable adiposity’ (FA) and ‘unfavourable adiposity’ (UFA) that are both associated with higher adiposity but with opposite effects on metabolic risk. We used these variants and two sample MR to test the effects on the chronic diseases.Results:MR identified two sets of diseases. First, 11 conditions where the metabolic effect of higher adiposity is the likely primary cause of the disease. Here, MR with the FA and UFA genetics showed opposing effects on risk of disease: coronary artery disease, peripheral artery disease, hypertension, stroke, type 2 diabetes, polycystic ovary syndrome, heart failure, atrial fibrillation, chronic kidney disease, renal cancer, and gout. Second, 9 conditions where the non-metabolic effects of excess weight (e.g. mechanical effect) are likely a cause. Here, MR with the FA genetics, despite leading to lower metabolic risk, and MR with the UFA genetics, both indicated higher disease risk: osteoarthritis, rheumatoid arthritis, osteoporosis, gastro-oesophageal reflux disease, gallstones, adult-onset asthma, psoriasis, deep vein thrombosis, and venous thromboembolism.Conclusions:Our results assist in understanding the consequences of higher adiposity uncoupled from its adverse metabolic effects, including the risks to individuals with high body mass index who may be relatively metabolically healthy.Funding:Diabetes UK, UK Medical Research Council, World Cancer Research Fund, National Cancer Institute

    Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

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    Background:Some individuals living with obesity may be relatively metabolically healthy, whilst others suffer from multiple conditions that may be linked to adverse metabolic effects or other factors. The extent to which the adverse metabolic component of obesity contributes to disease compared to the non-metabolic components is often uncertain. We aimed to use Mendelian randomisation (MR) and specific genetic variants to separately test the causal roles of higher adiposity with and without its adverse metabolic effects on diseases.Methods:We selected 37 chronic diseases associated with obesity and genetic variants associated with different aspects of excess weight. These genetic variants included those associated with metabolically ‘favourable adiposity’ (FA) and ‘unfavourable adiposity’ (UFA) that are both associated with higher adiposity but with opposite effects on metabolic risk. We used these variants and two sample MR to test the effects on the chronic diseases.Results:MR identified two sets of diseases. First, 11 conditions where the metabolic effect of higher adiposity is the likely primary cause of the disease. Here, MR with the FA and UFA genetics showed opposing effects on risk of disease: coronary artery disease, peripheral artery disease, hypertension, stroke, type 2 diabetes, polycystic ovary syndrome, heart failure, atrial fibrillation, chronic kidney disease, renal cancer, and gout. Second, 9 conditions where the non-metabolic effects of excess weight (e.g. mechanical effect) are likely a cause. Here, MR with the FA genetics, despite leading to lower metabolic risk, and MR with the UFA genetics, both indicated higher disease risk: osteoarthritis, rheumatoid arthritis, osteoporosis, gastro-oesophageal reflux disease, gallstones, adult-onset asthma, psoriasis, deep vein thrombosis, and venous thromboembolism.Conclusions:Our results assist in understanding the consequences of higher adiposity uncoupled from its adverse metabolic effects, including the risks to individuals with high body mass index who may be relatively metabolically healthy.Funding:Diabetes UK, UK Medical Research Council, World Cancer Research Fund, National Cancer Institute

    The Behavioral Roots of Information Systems Security:Exploring Key Factors Related to Unethical IT Use

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    Unethical information technology (IT) use, related to activities such as hacking, software piracy, phishing, and spoofing, has become a major security concern for individuals, organizations, and society in terms of the threat to information systems (IS) security. While there is a growing body of work on this phenomenon, we notice several gaps, limitations, and inconsistencies in the literature. In order to further understand this complex phenomenon and reconcile past findings, we conduct an exploratory study to uncover the nomological network of key constructs salient to this phenomenon, and the nature of their interrelationships. Using a scenario-based study of young adult participants, and both linear and nonlinear analyses, we uncover key nuances of this phenomenon of unethical IT use. We find that unethical IT use is a complex phenomenon, often characterized by nonlinear and idiosyncratic relationships between the constructs that capture it. Overall, ethical beliefs held by the individuals, along with economic, social, and technological considerations are found to be relevant to this phenomenon. In terms of practical implications, these results suggest that multiple interventions at various levels may be required to combat this growing threat to IS security

    The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.

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    BackgroundExcess bodyweight and related metabolic perturbations have been implicated in kidney cancer aetiology, but the specific molecular mechanisms underlying these relationships are poorly understood. In this study, we sought to identify circulating metabolites that predispose kidney cancer and to evaluate the extent to which they are influenced by body mass index (BMI).Methods and findingsWe assessed the association between circulating levels of 1,416 metabolites and incident kidney cancer using pre-diagnostic blood samples from up to 1,305 kidney cancer case-control pairs from 5 prospective cohort studies. Cases were diagnosed on average 8 years after blood collection. We found 25 metabolites robustly associated with kidney cancer risk. In particular, 14 glycerophospholipids (GPLs) were inversely associated with risk, including 8 phosphatidylcholines (PCs) and 2 plasmalogens. The PC with the strongest association was PC ae C34:3 with an odds ratio (OR) for 1 standard deviation (SD) increment of 0.75 (95% confidence interval [CI]: 0.68 to 0.83, p = 2.6 × 10-8). In contrast, 4 amino acids, including glutamate (OR for 1 SD = 1.39, 95% CI: 1.20 to 1.60, p = 1.6 × 10-5), were positively associated with risk. Adjusting for BMI partly attenuated the risk association for some-but not all-metabolites, whereas other known risk factors of kidney cancer, such as smoking and alcohol consumption, had minimal impact on the observed associations. A mendelian randomisation (MR) analysis of the influence of BMI on the blood metabolome highlighted that some metabolites associated with kidney cancer risk are influenced by BMI. Specifically, elevated BMI appeared to decrease levels of several GPLs that were also found inversely associated with kidney cancer risk (e.g., -0.17 SD change [ßBMI] in 1-(1-enyl-palmitoyl)-2-linoleoyl-GPC (P-16:0/18:2) levels per SD change in BMI, p = 3.4 × 10-5). BMI was also associated with increased levels of glutamate (ßBMI: 0.12, p = 1.5 × 10-3). While our results were robust across the participating studies, they were limited to study participants of European descent, and it will, therefore, be important to evaluate if our findings can be generalised to populations with different genetic backgrounds.ConclusionsThis study suggests a potentially important role of the blood metabolome in kidney cancer aetiology by highlighting a wide range of metabolites associated with the risk of developing kidney cancer and the extent to which changes in levels of these metabolites are driven by BMI-the principal modifiable risk factor of kidney cancer
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