107 research outputs found
Symmetry in Single-Polarization Reflector Impulse Radiating Antennas
There are various construction details for reflector impulse-radiating antennas (IRAs) which limit the achievement of the ideal performance characteristics. Symmetry planes are important for polarization purity in the direction of the main beam. This involves details of the feed cables, possible inclusion of a ground plane perpendicular to the ideal electric field, and location of perturbations in low-field regions. Another symmetry concerns the balancing of the low-frequency electric and magnetic dipoles by including special structures connected to the feed arms.В импульсных рефлекторных антеннах (IRAs) имеются различные детали конструкций, которые ограничивают возможность получения идеальных рабочих характеристик. Наличие плоскостей симметрии важно для чистоты поляризации в направлении основного луча. На это влияют детали кабелей питания, возможность включения плоскости земли перпендикулярно идеальному электрическому полю и положение возмущений в затененной области. Другая симметрия связана с уравновешиванием низкочастотных электрических и магнитных диполей за счет включения специальных структур, связанных с фидерными кронштейнами.У імпульсних рефлекторних антенах (IRAs) присутні різні деталі конструкцій, які обмежують можливість отримання ідеальних робочих характеристик. Наявність площин симетрії є важливою для чистоти поляризації у напрямку основного променя. На це впливають деталі кабелів живлення, можливість включення площини землі перпендикулярної ідеальному електричному полю та розміщення збурень у затіненій зоні. Друга симетрія пов’язана з урівноваженням низькочастотних електричних і магнітних диполів за рахунок включення спеціальних структур, пов’язаних з фідерними кронштейнами
Leading and higher twists in the proton polarized structure function at large Bjorken x
A phenomenological parameterization of the proton polarized structure
function has been developed for x > 0.02 using deep inelastic data up to ~ 50
(GeV/c)**2 as well as available experimental results on both photo- and
electro-production of proton resonances. According to the new parameterization
the generalized Drell-Hearn-Gerasimov sum rule is predicted to have a
zero-crossing point at Q**2 = 0.16 +/- 0.04 (GeV/c)**2. Then, low-order
polarized Nachtmann moments have been estimated and their Q**2-behavior has
been investigated in terms of leading and higher twists for Q**2 > 1
(GeV/c)**2. The leading twist has been treated at NLO in the strong coupling
constant and the effects of higher orders of the perturbative series have been
estimated using soft-gluon resummation techniques. In case of the first moment
higher-twist effects are found to be quite small for Q**2 > 1 (GeV/c)**2, and
the singlet axial charge has been determined to be a0[10 (GeV/c)**2] = 0.16 +/-
0.09. In case of higher order moments, which are sensitive to the large-x
region, higher-twist effects are significantly reduced by the introduction of
soft gluon contributions, but they are still relevant at Q**2 ~ few (GeV/c)**2
at variance with the case of the unpolarized transverse structure function of
the proton. Our finding suggests that spin-dependent correlations among partons
may have more impact than spin-independent ones. As a byproduct, it is also
shown that the Bloom-Gilman local duality is strongly violated in the region of
polarized electroproduction of the Delta(1232) resonance.Comment: revised version to appear in Phys. Rev. D; extended discussion on the
generalized DHG sum rul
Measurement of the - and -Dependence of the Asymmetry on the Nucleon
We report results for the virtual photon asymmetry on the nucleon from
new Jefferson Lab measurements. The experiment, which used the CEBAF Large
Acceptance Spectrometer and longitudinally polarized proton (NH) and
deuteron (ND) targets, collected data with a longitudinally
polarized electron beam at energies between 1.6 GeV and 5.7 GeV. In the present
paper, we concentrate on our results for and the related ratio
in the resonance and the deep inelastic regions for our lowest
and highest beam energies, covering a range in momentum transfer from
0.05 to 5.0 GeV and in final-state invariant mass up to about 3 GeV.
Our data show detailed structure in the resonance region, which leads to a
strong --dependence of for below 2 GeV. At higher , a
smooth approach to the scaling limit, established by earlier experiments, can
be seen, but is not strictly --independent. We add
significantly to the world data set at high , up to . Our data
exceed the SU(6)-symmetric quark model expectation for both the proton and the
deuteron while being consistent with a negative -quark polarization up to
our highest . This data setshould improve next-to-leading order (NLO) pQCD
fits of the parton polarization distributions.Comment: 7 pages LaTeX, 5 figure
Brain-based classification of youth with anxiety disorders: transdiagnostic examinations within the ENIGMA-Anxiety database using machine learning
Neuroanatomical findings on youth anxiety disorders are notoriously difficult to replicate, small in effect size and have limited clinical relevance. These concerns have prompted a paradigm shift toward highly powered (that is, big data) individual-level inferences, which are data driven, transdiagnostic and neurobiologically informed. Here we built and validated supervised neuroanatomical machine learning models for individual-level inferences, using a case–control design and the largest known neuroimaging database on youth anxiety disorders: the ENIGMA-Anxiety Consortium (N = 3,343; age = 10–25 years; global sites = 32). Modest, yet robust, brain-based classifications were achieved for specific anxiety disorders (panic disorder), but also transdiagnostically for all anxiety disorders when patients were subgrouped according to their sex, medication status and symptom severity (area under the receiver operating characteristic curve, 0.59–0.63). Classifications were driven by neuroanatomical features (cortical thickness, cortical surface area and subcortical volumes) in fronto-striato-limbic and temporoparietal regions. This benchmark study within a large, heterogeneous and multisite sample of youth with anxiety disorders reveals that only modest classification performances can be realistically achieved with machine learning using neuroanatomical data.NWORubicon 019.201SG.022Advanced Behavioural Research MethodsHealth and Well-bein
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Background:
In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation.
Methods:
This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. Those trial participants with hypoxia (oxygen saturation <92% on air or requiring oxygen therapy) and evidence of systemic inflammation (C-reactive protein ≥75 mg/L) were eligible for random assignment in a 1:1 ratio to usual standard of care alone versus usual standard of care plus tocilizumab at a dose of 400 mg–800 mg (depending on weight) given intravenously. A second dose could be given 12–24 h later if the patient's condition had not improved. The primary outcome was 28-day mortality, assessed in the intention-to-treat population. The trial is registered with ISRCTN (50189673) and ClinicalTrials.gov (NCT04381936).
Findings:
Between April 23, 2020, and Jan 24, 2021, 4116 adults of 21 550 patients enrolled into the RECOVERY trial were included in the assessment of tocilizumab, including 3385 (82%) patients receiving systemic corticosteroids. Overall, 621 (31%) of the 2022 patients allocated tocilizumab and 729 (35%) of the 2094 patients allocated to usual care died within 28 days (rate ratio 0·85; 95% CI 0·76–0·94; p=0·0028). Consistent results were seen in all prespecified subgroups of patients, including those receiving systemic corticosteroids. Patients allocated to tocilizumab were more likely to be discharged from hospital within 28 days (57% vs 50%; rate ratio 1·22; 1·12–1·33; p<0·0001). Among those not receiving invasive mechanical ventilation at baseline, patients allocated tocilizumab were less likely to reach the composite endpoint of invasive mechanical ventilation or death (35% vs 42%; risk ratio 0·84; 95% CI 0·77–0·92; p<0·0001).
Interpretation:
In hospitalised COVID-19 patients with hypoxia and systemic inflammation, tocilizumab improved survival and other clinical outcomes. These benefits were seen regardless of the amount of respiratory support and were additional to the benefits of systemic corticosteroids.
Funding:
UK Research and Innovation (Medical Research Council) and National Institute of Health Research
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