An HI survey of the Centaurus and Sculptor Groups - Constraints on the space density of low mass galaxies

We present results of two 21-cm HI surveys performed with the Australia Telescope Compact Array in the nearby Centaurus A and Sculptor galaxy groups. These surveys are sensitive to compact HI clouds and galaxies with HI masses as low as 3E+06 Msun, and are therefore among the most sensitive extragalactic HI surveys to date. The surveys consist of sparsely spaced pointings that sample approximately 2% of the groups' area on the sky. We detected previously known group members, but we found no new HI clouds or galaxies down to the sensitivity limit of the surveys. If the HI mass function had a faint end slope of alpha = 1.5 below M_{HI} = 10^{7.5} Msun in these groups, we would have expected ~3 new objects. Cold dark matter theories of galaxy formation predict the existence of a large number low mass DM sub-halos that might appear as tiny satellites in galaxy groups. Our results support and extend similar conclusions derived from previous HI surveys that a HI rich population of these satellites does not exist.Comment: Accepted for publication in A&

A Structural and Dynamical Study of Late-Type, Edge-On Galaxies: I. Sample Selection and Imaging Data

We present optical (B & R) and infrared (K_s) images and photometry for a sample of 49 extremely late-type, edge-on disk galaxies selected from the Flat Galaxy Catalog of Karenchentsev et al. (1993). Our sample was selected to include galaxies with particularly large axial ratios, increading the likelihood that the galaxies in the sample are truly edge-on. We have also concentrated the sample on galaxies with low apparent surface brightness, in order to increase the representation of intrinisically low surface brightness galaxies. Finally, the sample was chosen to have no apprarent bulges or optical warps so that the galaxies represent undisturbed, ``pure disk'' systems. The resulting sample forms the basis for a much larger spectroscopic study designed to place constraints on the physical quantities and processes which shape disk galaxies. The imaging data presented in this paper has been painstakingly reduced and calibrated to allow accurate surface photometry of features as faint as 30 mag/sqr-arcsec in B and 29 mag/sqr-arcsec in R on scales larger than 10 arcsec. Due to limitations in sky subtraction and flat fielding, the infrared data can reach only to 22.5 mag/sqr-arcsec in K_s on comparable scales. As part of this work, we have developed a new method for quantifying the reliability of surface photometry, which provides useful diagnostics for the presence of scattered light, optical emission from infrared cirrus, and other sources of non-uniform sky backgrounds.Comment: scheduled to appear in the Astronomical Journal, LaTeX, 36 pages including 7 pages of figures (fig 1-2,4). A low resolution version of Figure 3 is included in JPEG format; contours are seriously degraded. A full resolution Postscript version of Figure 3 (10.6Mb,gzipped) is available through anonymous ftp at ftp://ftp.astro.washington.edu/pub/users/jd/FGC/dalcanton.f3.ps.g

Comparing Galaxies and Lyman Alpha Absorbers at Low Redshift

A scenario is explored in which Lyman alpha absorbers at low redshift arise from lines of sight through extended galaxy disks, including those of dwarf and low surface brightness galaxies. A population of galaxies is simulated based upon observed distributions of galaxy properties, and the gas disks are modeled using pressure and gravity confinement. Some parameter values are ruled out by comparing simulation results with the observed galaxy luminosity function, and constraints may be made on the absorbing cross sections of galaxies. Simulation results indicate that it is difficult to match absorbers with particular galaxies observationally since absorption typically occurs at high impact parameters (>200 kpc) from luminous galaxies. Low impact parameter absorption is dominated by low luminosity dwarfs. A large fraction of absorption lines is found to originate from low surface brightness galaxies, so that the absorbing galaxy is likely to be misidentified. Low redshift Lyman alpha absorber counts can easily be explained by moderately extended galaxy disks when low surface brightness galaxies are included, and it is easily possible to find a scenario which is consistent with observed the galaxy luminosity function, with low redshift Lyman limit absorber counts, and with standard nucleosynthesis predictions of the baryon density, Omega_Baryon.Comment: 17 pages, 8 figures, accepted to the Astrophysical Journa

Tidal stirring and the origin of dwarf spheroidals in the Local Group

N-Body/SPH simulations are used to study the evolution of dwarf irregular galaxies (dIrrs) entering the dark matter halo of the Milky Way or M31 on plunging orbits. We propose a new dynamical mechanism driving the evolution of gas rich, rotationally supported dIrrs, mostly found at the outskirts of the Local Group (LG), into gas free, pressure supported dwarf spheroidals (dSphs) or dwarf ellipticals (dEs), observed to cluster around the two giant spirals. The initial model galaxies are exponential disks embedded in massive dark matter halos and reproduce nearby dIrrs. Repeated tidal shocks at the pericenter of their orbit partially strip their halo and disk and trigger dynamical instabilities that dramatically reshape their stellar component. After only 2-3 orbits low surface brightness (LSB) dIrrs are transformed into dSphs, while high surface brightness (HSB) dIrrs evolve into dEs. This evolutionary mechanism naturally leads to the morphology-density relation observed for LG dwarfs. Dwarfs surrounded by very dense dark matter halos, like the archetypical dIrr GR8, are turned into Draco or Ursa Minor, the faintest and most dark matter dominated among LG dSphs. If disks include a gaseous component, this is both tidally stripped and consumed in periodic bursts of star formation. The resulting star formation histories are in good qualitative agreement with those derived using HST color-magnitude diagrams for local dSphs.Comment: 5 pages, 5 figures, to appear on ApJL. Simulation images and movies can be found at the Local Group web page at http://pcblu.uni.mi.astro.it/~lucio/LG/LG.htm

Skin microbiota analysis in patients with anorexia nervosa and healthy-weight controls reveals microbial indicators of healthy weight and associations with the antimicrobial peptide psoriasin

Anorexia nervosa (AN), a psychiatric condition defined by low body weight for age and height, is associated with numerous dermatological conditions. Yet, clinical observations report that patients with AN do not suffer from infectious skin diseases like those associated with primary malnutrition. Cell-mediated immunity appears to be amplified in AN; however, this proinflammatory state does not sufficiently explain the lower incidence of infections. Antimicrobial peptides (AMPs) are important components of the innate immune system protecting from pathogens and shaping the microbiota. In Drosophila melanogaster starvation precedes increased AMP gene expression. Here, we analyzed skin microbiota in patients with AN and age-matched, healthy-weight controls and investigated the influence of weight gain on microbial community structure. We then correlated features of the skin microbial community with psoriasin and RNase 7, two highly abundant AMPs in human skin, to clarify whether an association between AMPs and skin microbiota exists and whether such a relationship might contribute to the resistance to cutaneous infections observed in AN. We find significant statistical correlations between Shannon diversity and the highly abundant skin AMP psoriasin and bacterial load, respectively. Moreover, we reveal psoriasin significantly associates with Abiotrophia, an indicator for the healthy-weight control group. Additionally, we observe a significant correlation between an individual’s body mass index and Lactobacillus, a microbial indicator of health. Future investigation may help clarify physiological mechanisms that link nutritional intake with skin physiology

Magnetic flux emergence in granular convection: Radiative MHD simulations and observational signatures

We study the emergence of magnetic flux from the near-surface layers of the solar convection zone into the photosphere. To model magnetic flux emergence, we carried out a set of numerical radiative magnetohydrodynamics simulations. Our simulations take into account the effects of compressibility, energy exchange via radiative transfer, and partial ionization in the equation of state. All these physical ingredients are essential for a proper treatment of the problem. Furthermore, the inclusion of radiative transfer allows us to directly compare the simulation results with actual observations of emerging flux. We find that the interaction between the magnetic flux tube and the external flow field has an important influence on the emergent morphology of the magnetic field. Depending on the initial properties of the flux tube (e.g. field strength, twist, entropy etc.), the emergence process can also modify the local granulation pattern. The emergence of magnetic flux tubes with a flux of $10^{19}$ Mx disturbs the granulation and leads to the transient appearance of a dark lane, which is coincident with upflowing material. These results are consistent with observed properties of emerging magnetic flux.Comment: To appear in A&

Specific Disease Knowledge as Predictor of Susceptibility to Availability Bias in Diagnostic Reasoning:a Randomized Controlled Experiment

BACKGROUND: Bias in reasoning rather than knowledge gaps has been identified as the origin of most diagnostic errors. However, the role of knowledge in counteracting bias is unclear. OBJECTIVE: To examine whether knowledge of discriminating features (findings that discriminate between look-alike diseases) predicts susceptibility to bias. DESIGN: Three-phase randomized experiment. Phase 1 (bias-inducing): Participants were exposed to a set of clinical cases (either hepatitis-IBD or AMI-encephalopathy). Phase 2 (diagnosis): All participants diagnosed the same cases; 4 resembled hepatitis-IBD, 4 AMI-encephalopathy (but all with different diagnoses). Availability bias was expected in the 4 cases similar to those encountered in phase 1. Phase 3 (knowledge evaluation): For each disease, participants decided (max. 2 s) which of 24 findings was associated with the disease. Accuracy of decisions on discriminating features, taken as a measure of knowledge, was expected to predict susceptibility to bias. PARTICIPANTS: Internal medicine residents at Erasmus MC, Netherlands. MAIN MEASURES: The frequency with which higher-knowledge and lower-knowledge physicians gave biased diagnoses based on phase 1 exposure (range 0-4). Time to diagnose was also measured. KEY RESULTS: Sixty-two physicians participated. Higher-knowledge physicians yielded to availability bias less often than lower-knowledge physicians (0.35 vs 0.97; p = 0.001; difference, 0.62 [95% CI, 0.28-0.95]). Whereas lower-knowledge physicians tended to make more of these errors on subjected-to-bias than on not-subjected-to-bias cases (p = 0.06; difference, 0.35 [CI, - 0.02-0.73]), higher-knowledge physicians resisted the bias (p = 0.28). Both groups spent more time to diagnose subjected-to-bias than not-subjected-to-bias cases (p = 0.04), without differences between groups. CONCLUSIONS: Knowledge of features that discriminate between look-alike diseases reduced susceptibility to bias in a simulated setting. Reflecting further may be required to overcome bias, but succeeding depends on having the appropriate knowledge. Future research should examine whether the findings apply to real practice and to more experienced physicians

Semi-Analytical Models for the Formation of Disk Galaxies II. Dark Matter versus Modified Newtonian Dynamics

We present detailed semi-analytical models for the formation of disk galaxies both in a Universe dominated by dark matter (DM), and in one for which the force law is given by modified Newtonian dynamics (MOND). We tune the models to fit the observed near-infrared Tully-Fisher (TF) relation, and compare numerous predictions of the resulting models with observations. The DM and MOND models are almost indistinguishable. They both yield gas mass fractions and dynamical mass-to-light ratios which are in good agreement with observations. Both models reproduce the narrow relation between global mass-to-light ratio and central surface brightness, and reveal a characteristic acceleration, contrary to claims that these relations are not predicted by DM models. Both models require SN feedback in order to reproduce the lack of high surface brightness dwarf galaxies. However, the introduction of feedback to the MOND models steepens the TF relation and increases the scatter, making MOND only marginally consistent with observations. The most serious problem for the DM models is their prediction of steep central rotation curves. However, the DM rotation curves are only slightly steeper than those of MOND, and are only marginally inconsistent with the poor resolution data on LSB galaxies.Comment: 26 pages, 11 figures. Accepted for publication in Ap

Asexual and sexual reproduction are two separate developmental pathways in a <i>Termitomyces</i> species

Although mutualistic symbioses per definition are beneficial for interacting species, conflict may arise if partners reproduce independently. We address how this reproductive conflict is regulated in the obligate mutualistic symbiosis between fungus-growing termites and Termitomyces fungi. Even though the termites and their fungal symbiont disperse independently to establish new colonies, dispersal is correlated in time. The fungal symbiont typically forms mushrooms a few weeks after the colony has produced dispersing alates. It is thought that this timing is due to a trade-off between alate and worker production; alate production reduces resources available for worker production. As workers consume the fungus, reduced numbers of workers will allow mushrooms to 'escape' from the host colony. Here, we test a specific version of this hypothesis: the typical asexual structures found in all species of Termitomyces-nodules-are immature stages of mushrooms that are normally harvested by the termites at a primordial stage. We refute this hypothesis by showing that nodules and mushroom primordia are macro- and microscopically different structures and by showing that in the absence of workers, primordia do, and nodules do not grow out into mushrooms. It remains to be tested whether termite control of primordia formation or of primordia outgrowth mitigates the reproductive conflict.</p