9,214 research outputs found
Generating functional analysis of complex formation and dissociation in large protein interaction networks
We analyze large systems of interacting proteins, using techniques from the
non-equilibrium statistical mechanics of disordered many-particle systems.
Apart from protein production and removal, the most relevant microscopic
processes in the proteome are complex formation and dissociation, and the
microscopic degrees of freedom are the evolving concentrations of unbound
proteins (in multiple post-translational states) and of protein complexes. Here
we only include dimer-complexes, for mathematical simplicity, and we draw the
network that describes which proteins are reaction partners from an ensemble of
random graphs with an arbitrary degree distribution. We show how generating
functional analysis methods can be used successfully to derive closed equations
for dynamical order parameters, representing an exact macroscopic description
of the complex formation and dissociation dynamics in the infinite system
limit. We end this paper with a discussion of the possible routes towards
solving the nontrivial order parameter equations, either exactly (in specific
limits) or approximately.Comment: 14 pages, to be published in Proc of IW-SMI-2009 in Kyoto (Journal of
Phys Conference Series
Estudo das atividades lipolĂticas de fungos isolados de riachos da regiĂŁo de Foz do Iguaçu - PR
Anais do V Encontro de Iniciação CientĂfica e I Encontro Anual de Iniciação ao Desenvolvimento TecnolĂłgico e Inovação – EICTI 2016 - 05 e 07 de outubro de 2016 – SessĂŁo CiĂŞncias Exatas e da TerraA busca por novas enzimas com atividades lipolĂticas apresenta-se como uma
importante alternativa no estabelecimento de novas tecnologias destinadas a processos
industriais sustentáveis. Com uma ampla gama de aplicações biotecnológicas, estas enzimas
(responsáveis pelas hidrĂłlises de Ă©steres e lipĂdios) apresentam papel biotecnolĂłgico
fundamental, sendo aplicadas desde a formulação de detergentes e biocombustĂveis atĂ©
sĂnteses complexas de polĂmeros e drogas biologicamente ativas [1]. Esta vasta gama de
aplicações requer a descoberta de novos biocatalisadores com propriedades biológicas
direcionadas, e isto incentiva o estudo dos mais deferentes nichos. Assim, fungos envolvidos
em processos de decomposição apresentam-se como ferramentas-chave na busca de novos
biocatalisadores, uma vez que estes micro-organismos tĂŞm sido associados Ă uma grande
produção de lipases extracelulares [2].
Nesse contexto, este trabalho apresenta um interessante estudo do potencial lipolĂtico
de uma microbiota isolada de detritos vegetais de riachos da região de Foz do Iguaçu – PR
aplicando técnicas qualitativas e quantitativas que permitam a investigação do potencial
enzimático da microbiota de interesse
Non-thermal origin of nonlinear transport across magnetically induced superconductor-metal-insulator transition
We have studied the effect of perpendicular magnetic fields and temperatures
on the nonlinear electronic transport in amorphous Ta superconducting thin
films. The films exhibit a magnetic field induced metallic behavior intervening
the superconductor-insulator transition in the zero temperature limit. We show
that the nonlinear transport in the superconducting and metallic phase is of
non-thermal origin and accompanies an extraordinarily long voltage response
time.Comment: 5 pages, 4 figure
Weak Quasi-elastic Production of Hyperons
The quasielastic weak production of and hyperons from
nucleons and nuclei induced by antineutrinos is studied in the energy region of
some ongoing neutrino oscillation experiments in the intermediate energy
region. The hyperon nucleon transition form factors determined from neutrino
nucleon scattering and an analysis of high precision data on semileptonic
decays of neutron and hyperons using SU(3) symmetry have been used. The nuclear
effects due to Fermi motion and final state interaction effects due to hyperon
nucleon scattering have also been studied. The numerical results for
differential and total cross sections have been presented.Comment: 26 pages, 10 figure
Tilt Induced Localization and Delocalization in the Second Landau Level
We have investigated the behavior of electronic phases of the second Landau
level under tilted magnetic fields. The fractional quantum Hall liquids at
2+1/5 and 2+4/5 and the solid phases at 2.30, 2.44, 2.57, and 2.70
are quickly destroyed with tilt. This behavior can be interpreted as a tilt
driven localization of the 2+1/5 and 2+4/5 fractional quantum Hall liquids and
a delocalization through melting of solid phases in the top Landau level,
respectively. The evolution towards the classical Hall gas of the solid phases
is suggestive of antiferromagnetic ordering
Innovation in accounting tasks: empirical study in two professional groups
The aim of this study is to contribute to the knowledge on innovation in accounting tasks, from the point of view of two professional groups. Its goals are: evaluating the importance given by the professionals to accounting tasks; identifying whether there is convergence between the two professional groups, regarding the importance of the tasks; examining whether there is an association between the professionals’ individual characteristics and the importance they attach to the tasks. Two professional groups were surveyed: 105 financial officers of the top 500 Portuguese companies; and 412 Chartered Accountants. The results obtained allowed us to conclude that the respondents attach more importance to the traditional tasks, linked to the concept of a monetary-oriented accountant, and less importance to the more innovative tasks, related to business strategy; there is no convergence between the two professional groups in terms of the importance of the accountants’ participation in the strategic tasks. Regarding the association between individual characteristics and the level of importance assigned to the accounting tasks, we found an influence of the following characteristics: gender; academic degree of the professionals; and the institution where that degree was obtained.info:eu-repo/semantics/publishedVersio
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