The Independent and Interactive Effects of the Big Five Personality Dimensions upon Dispositional Coping and Coping Effectiveness in Sport.

We examined the independent and interactive effects of the Big-Five personality traits on dispositional coping and coping effectiveness among athletes. Participants were 400 athletes (mean age 22.97, s =7.00) from the United Kingdom. The athletes completed measures of personality, dispositional coping, and coping effectiveness. The Big-Five personality traits independently predicted the use of higher-order coping dimensions. Extraversion, agreeableness, and openness positively predicted task-oriented coping. Neuroticism positively predicted distraction-oriented coping, whereas agreeableness, extraversion and conscientiousness were negative predictors. Both extraversion and neuroticism positively predicted disengagement-oriented coping, whereas agreeableness and conscientiousness were negative predictors. Only neuroticism predicted coping effectiveness, which emerged as a negative predictor. Findings also showed a two-way interaction effect for predicting task-oriented coping between neuroticism and openness, and between extraversion and neuroticism. A further two-way interaction effect for predicting distraction-oriented coping was found between agreeableness and conscientiousness. These findings reinforce the need to investigate not only independent, but also interactive effects of personality dimensions upon sport-related dispositional coping

The impact generated by public and charity-funded research in the UK: A systematic literature review

Objective: To identify, synthesize and critically assess the empirical evidence of the impact generated by public and charity funded health research in the United Kingdom. Methods: We conducted a systematic literature review of the empirical evidence published in English in peer-reviewed journals between 2006 and 2017. Studies meeting the inclusion criteria were selected and their findings were analysed using the Payback Framework into five main categories: knowledge, benefits to future research and research use, benefits from informing policy and product development, health and health sector benefits and broader economic benefits. We assessed the studies for risk of selection, reporting and funding bias. Results: Thirteen studies met the inclusion criteria. The majority of the studies (10 out of 13) assessed impact at multiple domains including the main 5 key themes of the Payback Framework. All of them showed a positive impact of funded research on outcomes. Of those studies, one presented low risk of bias (8%), 6 studies were classified as presenting moderate risk of bias (46%) and 6 studies presented high risk of bias (46%). Conclusions: Empirical evidence on the impact of public and charity funded research is still limited and subject to funding and selection bias. More work is needed to establish the causal effects of funded research on academic outcomes, policy, practice and the broader economy

January 31, 2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia

Hybrid Refining Approach of PrOnto Ontology

This paper presents a refinement of PrOnto ontology using a validation test based on legal experts’ annotation of privacy policies combined with an Open Knowledge Extraction (OKE) algorithm. To ensure robustness of the results while preserving an interdisciplinary approach, the integration of legal and technical knowledge has been carried out as follows. The set of privacy policies was first analysed by the legal experts to discover legal concepts and map the text into PrOnto. The mapping was then provided to computer scientists to perform the OKE analysis. Results were validated by the legal experts, who provided feedbacks and refinements (i.e. new classes and modules) of the ontology according to MeLOn methodology. Three iterations were performed on a set of (development) policies, and a final test using a new set of privacy policies. The results are 75,43% of detection of concepts in the policy texts and an increase of roughly 33% in the accuracy gain on the test set, using the new refined version of PrOnto enriched with SKOS-XL lexicon terms and definitions

Interactions in vivo between the Vif protein of HIV-1 and the precursor (Pr55GAG) of the virion nucleocapsid proteins

The abnormality of viral core structure seen in vif-defective HIV-1 grown in PBMCs has suggested a role for Vif in viral morphogenesis. Using an in vivo mammalian two-hybrid assay, the interaction between Vif and the precursor (Pr55GAG) of the virion nucleocapsid proteins has been analysed. This revealed the amino-terminal (aa 1–22) and central (aa 70–100) regions of Vif to be essential for its interaction with Pr55GAG, but deletion of the carboxy-terminal (aa 158–192) region of the protein had only a minor effect on its interaction. Initial deletion studies carried out on Pr55GAG showed that a 35-amino-acid region of the protein bridging the MA(p17)–CA(p24) junction was essential for its ability to interact with Vif. Site-directed mutagenesis of a conserved tryptophan (Trp21) near the amino terminus of Vif showed it to be important for the interaction with Pr55GAG. By contrast, mutagenesis of the highly conserved YLAL residues forming part of the BC-box motif, shown to be important in Vif promoting degradation of APOBEC3G/3F, had little or no effect on the Vif–Pr55GAG interaction