Clinical and Virological Features and Course of Acute Hepatitis B (AHB) in Italy

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Bone and joint infections in adults: a comprehensive classification proposal

Ten currently available classifications were tested for their ability to describe a continuous cohort of 300 adult patients affected by bone and joint infections. Each classification only focused, on the average, on 1.3\u2009\ub1\u20090.4 features of a single clinical condition (osteomyelitis, implant-related infections, or septic arthritis), being able to classify 34.8\u2009\ub1\u200924.7% of the patients, while a comprehensive classification system could describe all the patients considered in the study. RESULT AND CONCLUSION: A comprehensive classification system permits more accurate classification of bone and joint infections in adults than any single classification available and may serve for didactic, scientific, and clinical purposes

Prevention of implant-related infections by a resorbable, antibacterial-loaded coating: a new approach

Currently studied antibacterial coatings are far from having large-scale applications, due to various limitations. A recently developed fast resorbable, antibacterial-loaded, hydrogel coating may provide a new approach to offer an effective antibacterial and antibiofilm protection to orthopedic implants

A High Diffusive Model for Nanomaterials

Considerable attention is today devoted to the engineering of films widely used in photocatalytic, solar energy converters, photochemical and photoelectrochemical cells, dye-sensitized solar cells (DSSCs), to optimize electronic time response following photogeneration. However, the precise nature of transport processes in these systems has remained unresolved. To investigate such aspects of carrier dynamics, we have suggested a model for the calculation of correlation functions, expressed as the Fourier transform of the frequency-dependent complex conductivity σ(ω). Results are presented for the velocity correlation functions, the mean square deviation of position and the diffusion coefficient in systems, like TiO2 and doped Si, of large interest in present devices. Fast diffusion occurs in short time intervals of the order of few collision times. Consequences for efficiency of this fast response are discussed in relation to nanostructured devices

Perceptions of the appropriate response to norm violation in 57 societies

Norm enforcement may be important for resolving conflicts and promoting cooperation. However, little is known about how preferred responses to norm violations vary across cultures and across domains. In a preregistered study of 57 countries (using convenience samples of 22,863 students and non-students), we measured perceptions of the appropriateness of various responses to a violation of a cooperative norm and to atypical social behaviors. Our findings highlight both cultural universals and cultural variation. We find a universal negative relation between appropriateness ratings of norm violations and appropriateness ratings of responses in the form of confrontation, social ostracism and gossip. Moreover, we find the country variation in the appropriateness of sanctions to be consistent across different norm violations but not across different sanctions. Specifically, in those countries where use of physical confrontation and social ostracism is rated as less appropriate, gossip is rated as more appropriate.info:eu-repo/semantics/publishedVersio

EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI) : Study protocol for a multicentre, observational trial

More than 300 million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI. EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI. EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Münster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials. Trial registration number NCT04165369

Changes in social norms during the early stages of the COVID-19 pandemic across 43 countries

Data availability: The data generated in this study have been deposited in the Open Science Framework (https://doi.org/10.17605/OSF.IO/STKFR). Non-experimental data included in our datasets (i.e., intensity of government response to COVID-19 is the Stringency Index, COVID-19 deaths and cases per million) are taken from the Oxford COVID−19 Government Response Tracker [22 Hale, T. et al. A global panel database of pandemic policies (Oxford COVID−19 Government Response Tracker). Nat. Human Behav. https://doi.org/10.1038/s41562-021-01079-8 (2021).] and Our World in Data [38 Ritchie, H. et al. Coronavirus Pandemic (COVID-19). Our World in Data. https://ourworldindata.org/coronavirus (2020).] (downloaded November 2020). Wave 0 data are from [3 Gelfand, M. J. et al. Differences between tight and loose cultures: a 33-nation study. Science 332, 1100–1104 (2011).[ and Wave 1 data are from [5 Eriksson, K. et al. Perceptions of the appropriate response to norm violation in 57 societies. Nat. Commun. 12, 1481 (2021).].Code availability: The survey and analysis code are available at the Open Science Framework (https://doi.org/10.17605/OSF.IO/STKFR).Supplementary information is available online at: https://www.nature.com/articles/s41467-024-44999-5#Sec40 .The emergence of COVID-19 dramatically changed social behavior across societies and contexts. Here we study whether social norms also changed. Specifically, we study this question for cultural tightness (the degree to which societies generally have strong norms), specific social norms (e.g. stealing, hand washing), and norms about enforcement, using survey data from 30,431 respondents in 43 countries recorded before and in the early stages following the emergence of COVID-19. Using variation in disease intensity, we shed light on the mechanisms predicting changes in social norm measures. We find evidence that, after the emergence of the COVID-19 pandemic, hand washing norms increased while tightness and punishing frequency slightly decreased but observe no evidence for a robust change in most other norms. Thus, at least in the short term, our findings suggest that cultures are largely stable to pandemic threats except in those norms, hand washing in this case, that are perceived to be directly relevant to dealing with the collective threat.Knut and Wallenberg Grant “How do human norms form and change?” 2016.0167. (G.An.). The Swedish Research Council grant “Norms & Risk: Do social norms help dealing with collective threats” 2021-06271 (G.An.). Ministero dell’Istruzione dell’Università e della Ricerca, PRIN 2017, prot. 20178TRM3F (D.B.). Universidad de Los Andes, Fondo Vicerrectoría de Investigaciones (J.-C.C.). Ministry of Innovation and Technology of Hungary, National Research, Development and Innovation Fund NKFIH-OTKA K135963 (M.F.). Grant 23-061770 S of the Czech Science Foundation (M.H. and S.G.). RVO: 68081740 of the Institute of Psychology, Czech Academy of Sciences (M.H. and S.G.). RA Science Committee, research project N.20TTSH-070 (A.Gr. and N.Khac.). Open University of Israel, 511687 (R.N.). HSE University Basic Research Program (E.O.). Project BASIC (PID2022-141802NB-I00) funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe” (A.Sá.). US Army Research Office Grant W911NF-19-1-910281 (B.S.). Netherlands Organisation for Scientific Research, 019.183SG.001 (E.S.). Netherlands Organisation for Scientific Research, VI.Veni.201 G.013 (E.S.). European Commission, Horizon 2020-ID 870827 (E.S.). UKRI Grant “Secret Power” No. EP/X02170X/1 awarded under the European Commission’s “European Research Council - STG” Scheme (G.A.T.)