Tailoring teleportation to the quantum alphabet

We introduce a refinement of the standard continuous variable teleportation measurement and displacement strategies. This refinement makes use of prior knowledge about the target state and the partial information carried by the classical channel when entanglement is non-maximal. This gives an improvement in the output quality of the protocol. The strategies we introduce could be used in current continuous variable teleportation experiments.Comment: 16 pages, 6 figures, RevTeX, made changes as recommended by referee, other minor textual corrections, resubmitted to Phys. Rev.

Using flow geometry for drifter deployment in Lagrangian data assimilation

Methods of Lagrangian data assimilation (LaDA) require carefully chosen sites for optimal drifter deployments. In this work, we investigate a directed drifter deployment strategy with a recently developed LaDA method employing an augmented state vector formulation for an Ensemble Kalman filter. We test our directed drifter deployment strategy by targeting Lagrangian coherent flow structures of an unsteady double gyre flow to analyse how different release sites influence the performance of the method. We consider four different launch methods; a uniform launch, a saddle launch in which hyperbolic trajectories are targeted, a vortex centre launch, and a mixed launch targeting both saddles and centres. We show that global errors in the flow field require good dispersion of the drifters which can be realized with the saddle launch. Local errors on the other hand are effectively reduced by targeting specific flow features. In general, we conclude that it is best to target the strongest hyperbolic trajectories for shorter forecasts although vortex centres can produce good drifter dispersion upon bifurcating on longer time-scales

Crystal growth of ice Ih by revapor-deposition and diffusion suppression of monomolecular water in a polymer solid: spectroscopic observation of phase transition of water sorbed into solid polystyrene.

Monomolecular water in a solid polymer, which has no effective hydrogen bonding sites, was revealed by temperature-variable Fourier transform infrared spectroscopy to be condensable and crystallizable. Ice Ih formed in the polymer matrix was grown by vapor deposition and was reduced by sublimation. Moreover, rapid cooling induced crystal growth by vapor deposition during heating (revapor-deposition). These results indicate the requirement of a change in the generally accepted understanding of the thermal responses of water in a polymer matrix and give rise to a problem for general interpretation of the category of water in a polymer matrix based on calorimetrical analysis at very low water contents

Variational assimilation of Lagrangian data in oceanography

We consider the assimilation of Lagrangian data into a primitive equations circulation model of the ocean at basin scale. The Lagrangian data are positions of floats drifting at fixed depth. We aim at reconstructing the four-dimensional space-time circulation of the ocean. This problem is solved using the four-dimensional variational technique and the adjoint method. In this problem the control vector is chosen as being the initial state of the dynamical system. The observed variables, namely the positions of the floats, are expressed as a function of the control vector via a nonlinear observation operator. This method has been implemented and has the ability to reconstruct the main patterns of the oceanic circulation. Moreover it is very robust with respect to increase of time-sampling period of observations. We have run many twin experiments in order to analyze the sensitivity of our method to the number of floats, the time-sampling period and the vertical drift level. We compare also the performances of the Lagrangian method to that of the classical Eulerian one. Finally we study the impact of errors on observations.Comment: 31 page

Monitoring Ion Channel Function In Real Time Through Quantum Decoherence

In drug discovery research there is a clear and urgent need for non-invasive detection of cell membrane ion channel operation with wide-field capability. Existing techniques are generally invasive, require specialized nano structures, or are only applicable to certain ion channel species. We show that quantum nanotechnology has enormous potential to provide a novel solution to this problem. The nitrogen-vacancy (NV) centre in nano-diamond is currently of great interest as a novel single atom quantum probe for nanoscale processes. However, until now, beyond the use of diamond nanocrystals as fluorescence markers, nothing was known about the quantum behaviour of a NV probe in the complex room temperature extra-cellular environment. For the first time we explore in detail the quantum dynamics of a NV probe in proximity to the ion channel, lipid bilayer and surrounding aqueous environment. Our theoretical results indicate that real-time detection of ion channel operation at millisecond resolution is possible by directly monitoring the quantum decoherence of the NV probe. With the potential to scan and scale-up to an array-based system this conclusion may have wide ranging implications for nanoscale biology and drug discovery.Comment: 7 pages, 6 figure

Reactions at polymer interfaces: A Monte Carlo Simulation

Reactions at a strongly segregated interface of a symmetric binary polymer blend are investigated via Monte Carlo simulations. End functionalized homopolymers of different species interact at the interface instantaneously and irreversibly to form diblock copolymers. The simulations, in the framework of the bond fluctuation model, determine the time dependence of the copolymer production in the initial and intermediate time regime for small reactant concentration $\rho_0 R_g^3=0.163 ... 0.0406$. The results are compared to recent theories and simulation data of a simple reaction diffusion model. For the reactant concentration accessible in the simulation, no linear growth of the copolymer density is found in the initial regime, and a $\sqrt{t}$-law is observed in the intermediate stage.Comment: to appear in Macromolecule

Para to Ortho transition of metallic dimers on Si(001)

Extensive electronic structure calculations are performed to obtain the stable geometries of metals like Al, Ga and In on the Si(001) surface at 0.5 ML and 1 ML coverages. Our results coupled with previous theoretical findings explain the recent experimental data in a comprehensive fashion. At low coverages, as shown by previous works, `Para' dimers give the lowest energy structure. With increasing coverage beyond 0.5 ML, `Ortho' dimers become part of low energy configurations leading toward a `Para' to `Ortho' transition at 1 ML coverage. For In mixed staggered dimers (`Ortho' and `Para') give the lowest energy configuration. For Ga, mixed dimers are non-staggered, while for Al `Para' to `Ortho' transition of dimers is complete. Thus at intermediate coverages between 0.5 and 1 ML, the `Ortho' and `Para' dimers may coexist on the surface. Consequently, this may be an explanation of the fact that the experimental observations can be successfully interpreted using either orientation. A supported zigzag structure at 0.5 ML, which resembles ${\rm (CH)_x}$, does not undergo a dimerization transition, and hence stays semi-metallic. Also, unlike ${\rm (CH)_x}$ the soliton formation is ruled out for this structure.Comment: 8 pages, 6 figure

An investigation of the RWPE prostate derived family of cell lines using FTIR spectroscopy

Interest in developing robust, quicker and easier diagnostic tests for cancer has lead to an increased use of Fourier transform infrared (FTIR) spectroscopy to meet that need. In this study we present the use of different experimental modes of infrared spectroscopy to investigate the RWPE human prostate epithelial cell line family which are derived from the same source but differ in their mode of transformation and their mode of invasive phenotype. Importantly, analysis of the infrared spectra obtained using different experimental modes of infrared spectroscopy produces similar results. The RWPE family of cell lines can be separated into groups based upon the method of cell transformation rather than the resulting invasiveness/aggressiveness of the cell line. The study also demonstrates the possibility of using a genetic algorithm as a possible standardised pre-processing step and raises the important question of the usefulness of cell lines to create a biochemical model of prostate cancer progression

DNA replication stress restricts ribosomal DNA copy number

Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100–200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus. Copy number of rDNA repeat units in eukaryotic cells is maintained far in excess of the requirement for ribosome biogenesis. Despite the importance of the repeats for both ribosomal and non-ribosomal functions, it is currently not known how “normal” copy number is determined or maintained. To identify essential genes involved in the maintenance of rDNA copy number, we developed a droplet digital PCR based assay to measure rDNA copy number in yeast and used it to screen a yeast conditional temperature-sensitive mutant collection of essential genes. Our screen revealed that low rDNA copy number is associated with compromised DNA replication. Further, subculturing yeast under two separate conditions of DNA replication stress selected for a contraction of the rDNA array independent of the replication fork blocking protein, Fob1. Interestingly, cells with a contracted array grew better than their counterparts with normal copy number under conditions of DNA replication stress. Our data indicate that DNA replication stresses select for a smaller rDNA array. We speculate that this liberates scarce replication factors for use by the rest of the genome, which in turn helps cells complete DNA replication and continue to propagate. Interestingly, tumors from mini chromosome maintenance 2 (MCM2)-deficient mice also show a loss of rDNA repeats. Our data suggest that a reduction in rDNA copy number may indicate a history of DNA replication stress, and that rDNA array size could serve as a diagnostic marker for replication stress. Taken together, these data begin to suggest the selective pressures that combine to yield a “normal” rDNA copy number