886 research outputs found
Ytterbium divalency and lattice disorder in near-zero thermal expansion YbGaGe
While near-zero thermal expansion (NZTE) in YbGaGe is sensitive to
stoichiometry and defect concentration, the NZTE mechanism remains elusive. We
present x-ray absorption spectra that show unequivocally that Yb is nearly
divalent in YbGaGe and the valence does not change with temperature or with
nominally 1% B or 5% C impurities, ruling out a valence-fluctuation mechanism.
Moreover, substantial changes occur in the local structure around Yb with B and
C inclusion. Together with inelastic neutron scattering measurements, these
data indicate a strong tendency for the lattice to disorder, providing a
possible explanation for NZTE in YbGaGe.Comment: 4 pages, 4 figure, supplementary inf
Resolving the Ellsberg Paradox by Assuming that People Evaluate Repetitive Sampling
Ellsberg (1961) designed a decision experiment where most people violated the axioms of rational choice. He asked people to bet on the outcome of certain random events with known and with unknown probabilities. They usually preferred to bet on events with known probabilities. It is shown that this behavior is reasonable and in accordance with the axioms of rational decision making if it is assumed that people consider bets on events that are repeatedly sampled instead of just sampled once
The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland.
OBJECTIVES: To describe disease characteristics and treatment modalities in a multidisciplinary cohort of systemic lupus erythematosus (SLE) patients in Switzerland.
METHODS: Cross-sectional analysis of 255 patients included in the Swiss SLE Cohort and coming from centres specialised in Clinical Immunology, Internal Medicine, Nephrology and Rheumatology. Clinical data were collected with a standardised form. Disease activity was assessed using the Safety of Estrogens in Lupus Erythematosus National Assessment-SLE Disease Activity Index (SELENA-SLEDAI), an integer physician's global assessment score (PGA) ranging from 0 (inactive) to 3 (very active disease) and the erythrocyte sedimentation rate (ESR). The relationship between SLE treatment and activity was assessed by propensity score methods using a mixed-effect logistic regression with a random effect on the contributing centre.
RESULTS: Of the 255 patients, 82% were women and 82% were of European ancestry. The mean age at enrolment was 44.8 years and the median SLE duration was 5.2 years. Patients from Rheumatology had a significantly later disease onset. Renal disease was reported in 44% of patients. PGA showed active disease in 49% of patients, median SLEDAI was 4 and median ESR was 14 millimetre/first hour. Prescription rates of anti-malarial drugs ranged from 3% by nephrologists to 76% by rheumatologists. Patients regularly using anti-malarial drugs had significantly lower SELENA-SLEDAI scores and ESR values.
CONCLUSION: In our cohort, patients in Rheumatology had a significantly later SLE onset than those in Nephrology. Anti-malarial drugs were mostly prescribed by rheumatologists and internists and less frequently by nephrologists, and appeared to be associated with less active SLE
Local lattice disorder in the geometrically-frustrated spin glass pyrochlore Y2Mo2O7
The geometrically-frustrated spin glass Y2Mo2O7 has been considered widely to
be crystallographically ordered with a unique nearest neighbor magnetic
exchange interaction, J. To test this assertion, we present x-ray-absorption
fine-structure results for the Mo and Y K edges as a function of temperature
and compare them to results from a well-ordered pyrochlore, Tl2Mn2O7. We find
that the Mo-Mo pair distances are significantly disordered at approximately
right angles to the Y-Mo pairs. These results strongly suggest that lattice
disorder nucleates the spin-glass phase in this material.Comment: 9 pages, 2 Postscript figures, Phys. Rev. B: Rapid, in pres
Compton scattering beyond the impulse approximation
We treat the non-relativistic Compton scattering process in which an incoming
photon scatters from an N-electron many-body state to yield an outgoing photon
and a recoil electron, without invoking the commonly used frameworks of either
the impulse approximation (IA) or the independent particle model (IPM). An
expression for the associated triple differential scattering cross section is
obtained in terms of Dyson orbitals, which give the overlap amplitudes between
the N-electron initial state and the (N-1) electron singly ionized quantum
states of the target. We show how in the high energy transfer regime, one can
recover from our general formalism the standard IA based formula for the cross
section which involves the ground state electron momentum density (EMD) of the
initial state. Our formalism will permit the analysis and interpretation of
electronic transitions in correlated electron systems via inelastic x-ray
scattering (IXS) spectroscopy beyond the constraints of the IA and the IPM.Comment: 7 pages, 1 figur
Comparative Survival of Asian and White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel
There are few data regarding disparities in overall survival (OS) between Asian and white men with metastatic castration-resistant prostate cancer (mCRPC). We compared OS of Asian and white mCRPC men treated in phase III clinical trials with docetaxel and prednisone (DP) or a DP-containing regimen. Individual participant data from 8820 men with mCRPC randomly assigned on nine phase III trials to receive DP or a DP-containing regimen were combined. Men enrolled in these trials had a diagnosis of prostate adenocarcinoma. The median overall survival was 18.8 months (95% confidence interval [CI] = 17.4 to 22.1 months) and 21.2 months (95% CI = 20.8 to 21.7 months) for Asian and white men, respectively. The pooled hazard ratio for death for Asian men compared with white men, adjusted for baseline prognostic factors, was 0.95 (95% CI = 0.84 to 1.09), indicating that Asian men were not at increased risk of death. This large analysis showed that Asian men did not have shorter OS duration than white men treated with docetaxel
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