Flood plain management through allocation of land uses–a dynamic programming model

Despite heroic structural measures, flood damages continue to rise. This research develops a means for identifying more nearly optimal patterns of land use with particular reference to timing, depth, and duration of flooding. The major premise is that flood plain management is best viewed as a problem of allocating land uses to land parcels. A dynamic programming model is developed to determine what combination of downstream uses, which require flood protection, and upstream uses, which may increase runoff or provide protection through longer water retention, should be encouraged. The dynamic programming model and an associated simplified routing technique are demonstrated on a real watershed. Desirable extensions of the model are identified. One major result of the project is the realization of a need to classify watersheds by the degree of effective interdependence among land use decisions so as to determine the most appropriate types of analytical model s and public sector interventions for particular cases. Thinking about flood management as a problem of land use allocation is shown to be a fruitful conceptualization for exploring the issues, for developing models, and for identifying appropriate public sector interventions.U.S. Geological SurveyU.S. Department of the InteriorOpe

Model for floodplain management in urbanizing areas

A target land use pattern found using a dynamic programming model is shown to be a useful reference for comparing the success of floodplain management policies. At least in the test case, there is interdependence in the land use allocation for floodplain management--that is, a good solution includes some reduction of current land use in the floodplain and some provision of detention storage. For the test case, current floodplain management policies are not sufficient; some of the existing floodplain use should be removed. Although specific land use patterns are in part sensitive to potential error in land value data and to inaccuracy in the routing model, the general conclusion that some existing use must be removed is stable within the range of likely error. Trend surface analysis is shown to be a potentially useful way of generating bid price data for use in land use allocation models. Sensitivity analysis of the dynamic programming model with respect to routing of hydrographs is conducted through simulation based on expected distributions of error.U.S. Geological SurveyU.S. Department of the InteriorOpe

Turbine Disk Retirement-for-Cause: Measurement of Inspection Uncertainty for Disk Eddy Current Inspections

Major cost savings are possible through life extension of high-cost jet engine components until damage develops. Retirement-for-cause (RFC) decisions will be based upon both non-destructive inspection (NDI) to detect and size defects, and engineering analysis to assess defect severity under future usage. Failure Analysis Associates is performing a three-year program for ARPA/AFML to define and verify an optimum RFC strategy for jet engine disks. In depth, quantitative characterization of NDI performance is a major part of this project. This presentation summarizes the quantitative evaluation of inspection (NDI) uncertainty for four independent inspections - two state-of-the-art eddy current inspections of disk bolt holes, one with conventional hardware but improved signal processing, and one higher resolution eddy current inspection system assembled for this project. Separate inspections of the same 490 bolt holes in 49, 3rd stage disks retired from service in TF33 engines were performed with each of the four NDI techniques. Inspection results were compared with each other and with the actual cracks measured by surface plastic replicas and selected destructive metallography. The variation of detection probability and sizing errors with flaw size and indication level is defined in a form suitable.for the probabilistic reliability analysis and RFC strategy formulation. Progress in the other project tasks, especially the stress and fracture mechanics analysis to define the conditional failure probability if a flaw of specified size were present will also be summarized

Optical Morphologies of Millijansky Radio Galaxies Observed by HST and in the VLA FIRST Survey

We report on a statistical study of the 51 radio galaxies at the millijansky flux level from the Faint Images of the Radio Sky at Twenty centimeters, including their optical morphologies and structure obtained with the Hubble Space Telescope. Our optical imaging is significantly deeper (~2 mag) than previous studies with the superior angular resolution of space-based imaging. We that find 8/51 (16%) of the radio sources have no optically identifiable counterpart to AB~24 mag. For the remaining 43 sources, only 25 are sufficiently resolved in the HST images to reliably assign a visual classification: 15 (60%) are elliptical galaxies, 2 (8%) are late-type spiral galaxies, 1 (4%) is an S0, 3 (12%) are point-like objects (quasars), and 4 (16%) are merger systems. We find a similar distribution of optical types with measurements of the Sersic index. The optical magnitude distribution of these galaxies peaks at I~20.7+-0.5 AB mag, which is ~3 mag brighter than the depth of our typical HST field and is thus not due to the WFPC2 detection limit. This supports the luminosity-dependent density evolutionary model, where the majority of faint radio galaxies typically have L*-optical luminosities and a median redshift of z~0.8 with a relatively abrupt redshift cut-off at z>~2. We discuss our results in the context of the evolution of elliptical galaxies and active galactic nuclei.Comment: 20 pages, 8 figures, 51 galaxy images, and 5 tables. Uses emulateapj.cls and natbib.sty. Accepted to ApJS. High resolution images are available upon reques

A galactic-scale origin for stellar clustering

We recently presented a model for the cluster formation efficiency (CFE), i.e. the fraction of star formation occurring in bound stellar clusters. It utilizes the idea that the formation of stars and stellar clusters occurs across a continuous spectrum of ISM densities. Bound stellar clusters naturally arise from the high-density end of this density spectrum. Due to short free-fall times, these high-density regions can achieve high star formation efficiencies (SFEs) and can be unaffected by gas expulsion. Lower-density regions remain gas-rich and substructured, and are unbound upon gas expulsion. The model enables the CFE to be calculated using galactic-scale observables. I present a brief summary of the model physics, assumptions and caveats, and show that it agrees well with observations. Fortran and IDL routines for calculating the CFE are publicly available at http://www.mpa-garching.mpg.de/cfe.Comment: 4 pages, 1 figure; to appear in The Labyrinth of Star Formation, (eds.) D. Stamatellos, S. Goodwin, and D. Ward-Thompson, Springer, in pres

Ruptured ovarian cystic teratoma in pregnancy with diffuse peritoneal reaction mimicking advanced ovarian malignancy: a case report

<p>Abstract</p> <p>Introduction</p> <p>This case illustrates the unusual complication of granulomatous peritonitis following rupture of a dermoid cyst in pregnancy resembling disseminated ovarian carcinoma. To the best of the authors' knowledge, this is the first report of this complication during advanced pregnancy in the literature.</p> <p>Case presentation</p> <p>A dermoid cyst ruptured during surgical removal in the second trimester of pregnancy in a 27-year-old primigravida. Postoperatively the patient suffered pulmonary embolism and leakage of sebaceous material through the abdominal wound. She gradually developed significant abdominal distension, gastrointestinal symptoms and lost more than 8 kg of weight in the 12 weeks postoperatively. The baby was delivered at 31 weeks by a technically challenging caesarean section owing to severe dense adhesions obscuring the uterus. Bowel resection was performed for suspected malignant infiltration and adhesion causing obstruction. She had a protracted convalescence with an ileostomy and mucus fistula. Histology confirmed granulation without malignancy. One year following the surgical treatment, she had recovered well and was planning her next pregnancy.</p> <p>Conclusion</p> <p>Although granulomatous peritonitis following rupture of a dermoid cyst is very rare, awareness is the key to diagnosis and appropriate management. Per-operative frozen section may be helpful.</p

Neanderthals on the Lower Danube: Middle Palaeolithic evidence in the Danube Gorges of the Balkans

The article presents evidence about the Middle Palaeolithic and Middle to Upper Palaeolithic transition interval in the karst area of the Danube Gorges in the Lower Danube Basin. We review the extant data and present new evidence from two recently investigated sites found on the Serbian side of the Danube River – Tabula Traiana and Dubočka-Kozja caves. The two sites have yielded layers dating to both the Middle and Upper Palaeolithic and have been investigated by the application of modern standards of excavation and recovery along with a suite of state-of-the-art analytical procedures. The presentation focuses on micromorphological analyses of the caves’ sediments, characterisation of cryptotephra, a suite of new radiometric dates (accelerator mass spectrometry and optically stimulated luminescence) as well as proteomics (zooarchaeology by mass spectrometry) and stable isotope data in discerning patterns of human occupation of these locales over the long term

Neanderthals on the Lower Danube: Middle Palaeolithic evidence in the Danube Gorges of the Balkans

The article presents evidence about the Middle Palaeolithic and Middle to Upper Palaeolithic transition interval in the karst area of the Danube Gorges in the Lower Danube Basin. We review the extant data and present new evidence from two recently investigated sites found on the Serbian side of the Danube River – Tabula Traiana and Dubočka-Kozja caves. The two sites have yielded layers dating to both the Middle and Upper Palaeolithic and have been investigated by the application of modern standards of excavation and recovery along with a suite of state-of-the-art analytical procedures. The presentation focuses on micromorphological analyses of the caves’ sediments, characterisation of cryptotephra, a suite of new radiometric dates (accelerator mass spectrometry and optically stimulated luminescence) as well as proteomics (zooarchaeology by mass spectrometry) and stable isotope data in discerning patterns of human occupation of these locales over the long term

Molecular basis of structure and function of the microvillus membrane of intestinal epithelial cells

Correlation of molecular structure with biochemical functions of the plasma membrane of the microvilli of intestinal epithelial cells has been investigated by biochemical and electron microscopic procedures. Repeating particles, measuring approximately 60 &#197;in diameter, were found on the surface of the microvilli membrane which had been isolated or purified from rabbit intestinal epithelial cells and negatively stained with phosphotungstic acid. These particles were proved to be inherent components of the microvillus membrane, attached to the outer surface of its trilaminar structure, and were designated as the elementary particles of the microvilli of intestinal epithelial cells. Biochemical and electron microscopic identification of these elementary particles has been carried out by isolation of the elementary particles with papain from the isolated microvillus membrane, followed by purification of the particles by chromatographies on DEAE-cellulose and Sephadex columns. The partially purified particles containing invertase and leucine aminopeptidase are similar in size and structure to those of the elementary particles in the microvillus membrane. Evidence indicates that each of the elementary particles coincide with or include an enzyme molecule such as disaccharidase or peptidase, which carry out the terminal hydrolytic digestion of carbohydrates and proteins, respectively, on the surface of the microvillus membrane. Magnesium ionactivated adenosine triphosphatase and alkaline phosphatase cannot be solubilized with papain but remains in the smooth-surface membrane after the elementary particles have been removed. Cytochemical electron microscopic observation revealed that the active site of magnesium ion-activated adenosine triphosphatase is localized predominantly in the inner surface of the trilaminar structure of the microvillus membrane.</p

Effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock. The VANISH Randomized Clinical Trial

IMPORTANCE: Norepinephrine is currently recommended as the first-line vasopressor in septic shock; however, early vasopressin use has been proposed as an alternative. OBJECTIVE: To compare the effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock. DESIGN, SETTING, AND PARTICIPANTS: A factorial (2×2), double-blind, randomized clinical trial conducted in 18 general adult intensive care units in the United Kingdom between February 2013 and May 2015, enrolling adult patients who had septic shock requiring vasopressors despite fluid resuscitation within a maximum of 6 hours after the onset of shock. INTERVENTIONS: Patients were randomly allocated to vasopressin (titrated up to 0.06 U/min) and hydrocortisone (n = 101), vasopressin and placebo (n = 104), norepinephrine and hydrocortisone (n = 101), or norepinephrine and placebo (n = 103). MAIN OUTCOMES AND MEASURES: The primary outcome was kidney failure-free days during the 28-day period after randomization, measured as (1) the proportion of patients who never developed kidney failure and (2) median number of days alive and free of kidney failure for patients who did not survive, who experienced kidney failure, or both. Rates of renal replacement therapy, mortality, and serious adverse events were secondary outcomes. RESULTS: A total of 409 patients (median age, 66 years; men, 58.2%) were included in the study, with a median time to study drug administration of 3.5 hours after diagnosis of shock. The number of survivors who never developed kidney failure was 94 of 165 patients (57.0%) in the vasopressin group and 93 of 157 patients (59.2%) in the norepinephrine group (difference, -2.3% [95% CI, -13.0% to 8.5%]). The median number of kidney failure-free days for patients who did not survive, who experienced kidney failure, or both was 9 days (interquartile range [IQR], 1 to -24) in the vasopressin group and 13 days (IQR, 1 to -25) in the norepinephrine group (difference, -4 days [95% CI, -11 to 5]). There was less use of renal replacement therapy in the vasopressin group than in the norepinephrine group (25.4% for vasopressin vs 35.3% for norepinephrine; difference, -9.9% [95% CI, -19.3% to -0.6%]). There was no significant difference in mortality rates between groups. In total, 22 of 205 patients (10.7%) had a serious adverse event in the vasopressin group vs 17 of 204 patients (8.3%) in the norepinephrine group (difference, 2.5% [95% CI, -3.3% to 8.2%]). CONCLUSIONS AND RELEVANCE: Among adults with septic shock, the early use of vasopressin compared with norepinephrine did not improve the number of kidney failure-free days. Although these findings do not support the use of vasopressin to replace norepinephrine as initial treatment in this situation, the confidence interval included a potential clinically important benefit for vasopressin, and larger trials may be warranted to assess this further. TRIAL REGISTRATION: clinicaltrials.gov Identifier: ISRCTN 20769191