Foster Care Adoption: An Overview of Challenges Experienced by Parents

Purpose: This research strives to understand challenges of parents adopting foster children. Design and Methods: A qualitative, semi-structured interview was used to collect data from 11 social workers on their experiences working with adoptive parents. Findings: Findings indicate clear challenges/needs for these adoptive parents pursuing. Identified needs include quality training/education, desirable parental qualities, adoption-competent professionals, support, and resources to help with challenges brought by adoptive parents, the child and system. Implications: Findings enforce the importance of best practices though continuing research and the need for improvements to policy and practice. Several policy suggestions are made include ensuring timely delivery of information to adoptive parents, listing of all available children on the state adoption exchange, and to eliminate adoption disincentives

Foster Care Adoption: An Overview of Challenges Experienced by Parents

Purpose: This research strives to understand challenges of parents adopting foster children. Design and Methods: A qualitative, semi-structured interview was used to collect data from 11 social workers on their experiences working with adoptive parents. Findings: Findings indicate clear challenges/needs for these adoptive parents pursuing. Identified needs include quality training/education, desirable parental qualities, adoption-competent professionals, support, and resources to help with challenges brought by adoptive parents, the child and system. Implications: Findings enforce the importance of best practices though continuing research and the need for improvements to policy and practice. Several policy suggestions are made include ensuring timely delivery of information to adoptive parents, listing of all available children on the state adoption exchange, and to eliminate adoption disincentives

Evolution of shuttle avionics redundancy management/fault tolerance

The challenge of providing redundancy management (RM) and fault tolerance to meet the Shuttle Program requirements of fail operational/fail safe for the avionics systems was complicated by the critical program constraints of weight, cost, and schedule. The basic and sometimes false effectivity of less than pure RM designs is addressed. Evolution of the multiple input selection filter (the heart of the RM function) is discussed with emphasis on the subtle interactions of the flight control system that were found to be potentially catastrophic. Several other general RM development problems are discussed, with particular emphasis on the inertial measurement unit RM, indicative of the complexity of managing that three string system and its critical interfaces with the guidance and control systems

Selection of mouse cells with amplified metallothionein genes retaining their glucocorticoid inducibility

AbstractTwo new mouse cell mutants, resistant to either 80 or 100 mM CdCl2, were isolated to study the regulation of transcription by the glucocorticoid hormones. Their metallothionein mt-1+ and mt-2+ genes were amplified coordinately to a maximum of 30 copies per cell. By Southern blot analysis, no gross rearrangement was detectable near the mt+ loci. Contrary to other mutants previously isolated, the metallothionein-specific mRNAs of these mutants are inducible by dexamethasone

THE VARIABLE GENOMIC ARCHITECTURE OF ISOLATION BETWEEN HYBRIDIZING SPECIES OF HOUSE MICE

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75350/1/EVO_846_sm_FigS3A.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/75350/2/EVO_846_sm_legend.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/75350/3/EVO_846_sm_FigS4.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/75350/4/j.1558-5646.2009.00846.x.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/75350/5/EVO_846_sm_FigS1.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/75350/6/EVO_846_sm_FigS2.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/75350/7/EVO_846_sm_FigS3B.pd

Psychophysiological Responses to Data Visualization and Visualization Effects on Auditors’ Judgments and Audit Quality

We conduct experiments with practicing Big 4 auditors and business students in order to investigate the psychophysiological responses to Big Data visualizations and the effects of different visualization techniques on auditor judgment and ultimately audit quality. More specifically, the first experiment with students examines whether visualizations can be designed to increase the level of a users’ arousal. Such increases in arousal have the capacity to yield significant benefits to the audit profession by drawing auditors’ attention to important patterns in data and promoting the evaluation of these patterns during evidence evaluation. Results of the first experiment using cognitive pupillometry and eye gaze measurement indicate that different visualization techniques produce significant differences in the level of arousal without interfering with information evaluation efficiency. The second experiment then investigates whether visualizations that were shown to promote higher and lower levels of arousal have differential effects on auditor judgments and audit quality. In addition, the second experiment investigates whether the reliability of the data sources underlying visualizations affect auditors’ judgments. Results from the second experiment indicate that visualizations that increase arousal enhance auditors’ ability to recognize disconfirming evidence and incorporate this evidence into their decisions. That is, auditors who view visualizations of disconfirming evidence that are designed to promote arousal recommend greater reductions to management estimates of reported revenue and increase their budgeted audit hours more than auditors who view visualizations that promote less arousal. In addition, auditors who view visualizations that increase arousal are more likely to attend to the reliability of data used to create the visualizations. Overall, the experiments reveal that understanding the root causes of different visualization techniques on arousal and auditor judgment present multiple opportunities to enhance audit quality

Shelled pteropods in peril: Assessing vulnerability in a high CO2 ocean

The impact of anthropogenic ocean acidification (OA) on marine ecosystems is a vital concern facing marine scientists and managers of ocean resources. Euthecosomatous pteropods (holoplanktonic gastropods) represent an excellent sentinel for indicating exposure to anthropogenic OA because of the sensitivity of their aragonite shells to the OA conditions less favorable for calcification. However, an integration of observations, experiments and modelling efforts is needed to make accurate predictions of how these organisms will respond to future changes to their environment. Our understanding of the underlying organismal biology and life history is far from complete and must be improved if we are to comprehend fully the responses of these organisms to the multitude of stressors in their environment beyond OA. This review considers the present state of research and understanding of euthecosomatous pteropod biology and ecology of these organisms and considers promising new laboratory methods, advances in instrumentation (such as molecular, trace elements, stable isotopes, palaeobiology alongside autonomous sampling platforms, CT scanning and high-quality video recording) and novel field-based approaches (i.e. studies of upwelling and CO2 vent regions) that may allow us to improve our predictive capacity of their vulnerability and/or resilience. In addition to playing a critical ecological and biogeochemical role, pteropods can offer a significant value as an early-indicator of anthropogenic OA. This role as a sentinel species should be developed further to consolidate their potential use within marine environmental management policy making

Tradeoff Analysis for Combat Service Support Wireless Communications Alternatives

As the Army moves toward more mobile and agile forces and continued sustainment of numerous high-cost legacy logistics management systems, the requirement for wireless connectivity and a wireless network to supporting organizations has become ever more critical. There are currently several Army communications initiatives underway to resolve this wireless connectivity issue. However, to fully appreciate and understand the value of these initiatives, a Tradeoff Analysis is needed. The present study seeks to identify and assess solutions. The analysis identified issues that impede Interim Brigade Combat Team (IBCT) communication system integration and outlined core requirements for sharing of logistics data between the field and Army battle command systems. Then, the analysis examined wireless communication alternatives as possible solutions for IBCT logistics communications problems. The current baseline system was compared with possible alternatives involving tactical radio systems, wireless/near term digital radio, cellular satellite, and third-generation (3G) wireless technologies. Cellular satellite and 3G wireless technologies offer clear advantages and should be considered for later IBCTs

Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22

A substantial proportion of familial colorectal cancer (CRC) is not a consequence of known susceptibility loci, such as mismatch repair (MMR) genes, supporting the existence of additional loci. To identify novel CRC loci, we conducted a genome-wide linkage scan in 356 white families with no evidence of defective MMR (i.e., no loss of tumor expression of MMR proteins, no microsatellite instability (MSI)-high tumors, or no evidence of linkage to MMR genes). Families were ascertained via the Colon Cancer Family Registry multi-site NCI-supported consortium (Colon CFR), the City of Hope Comprehensive Cancer Center, and Memorial University of Newfoundland. A total of 1,612 individuals (average 5.0 per family including 2.2 affected) were genotyped using genome-wide single nucleotide polymorphism linkage arrays; parametric and non-parametric linkage analysis used MERLIN in a priori-defined family groups. Five lod scores greater than 3.0 were observed assuming heterogeneity. The greatest were among families with mean age of diagnosis less than 50 years at 4q21.1 (dominant HLOD = 4.51, α = 0.84, 145.40 cM, rs10518142) and among all families at 12q24.32 (dominant HLOD = 3.60, α = 0.48, 285.15 cM, rs952093). Among families with four or more affected individuals and among clinic-based families, a common peak was observed at 15q22.31 (101.40 cM, rs1477798; dominant HLOD = 3.07, α = 0.29; dominant HLOD = 3.03, α = 0.32, respectively). Analysis of families with only two affected individuals yielded a peak at 8q13.2 (recessive HLOD = 3.02, α = 0.51, 132.52 cM, rs1319036). These previously unreported linkage peaks demonstrate the continued utility of family-based data in complex traits and suggest that new CRC risk alleles remain to be elucidated. © 2012 Cicek et al