Sensitivity of freshwater periphytic diatoms to agricultural herbicides

The biomonitoring of pesticide pollution in streams and rivers using algae such as diatoms remains difficult. The responses of diatomcommunities to toxic stress in streamwater are disturbed by the variations of environmental parameters. In this study, periphytic algae collected in situwere exposed under controlled conditions to two major herbicides used in French agriculture (isoproturon and s-metolachlor). Three exposure regimes were tested: 5 and 30gL−1 for 6 days and 30gL−1 for 3 days followed by a recovery period of 3 days. The algal biomasses were assessed from pigment concentrations (chlorophyll a and c) and from live cell density. The highest concentration (30gL−1) of isoproturon inhibited the biomass increase statistically significantly. In periphyton exposed to 5 and 30gL−1 of s-metolachlor, chlorophyll c concentration and live cell densitywere also statistically significantly lower than in the control. Periphyton left to recover after reduced exposure duration (3 days) showed higher growth rates after treatment with s-metolachlor than with isoproturon. Taxonomic identifications showed that species like Melosira varians, Nitzschia dissipata and Cocconeis placentula were not affected by the herbicide exposure. Other species like Eolimna minima and Navicula reichardtiana were more sensitive. Studying diatoms according to their trophic mode showed that facultative heterotroph specieswere statistically significantly favoured by isoproturon exposure at the highest concentration. Results obtained with s-metolachlor exposure showed a disturbance of cell multiplication rather than that of photosynthesis. These results suggest that photosynthesis inhibitors like isoproturon favour species able to survive when the autotroph mode is inhibited

Travelling-waves consistent with turbulence-driven secondary flow in a square duct

We present numerically determined travelling-wave solutions for pressure-driven flow through a straight duct with a square cross-section. This family of solutions represents typical coherent structures (a staggered array of counter-rotating streamwise vortices and an associated low-speed streak) on each wall. Their streamwise average flow in the cross-sectional plane corresponds to an eight vortex pattern much alike the secondary flow found in the turbulent regime

Technical communication. Perspectives for the Eighties, part 2

The importance of technical writing as a separate discipline is suggested. Some specific areas addressed were: technical writing skills industry needs, definitions of technical writing, the hows and whys of inhouse writing, and the nature of the composing process in technical comunication

Entrepreneurial value creation: conceptualizing an exchange-based view of entrepreneurship

4sìopenPurpose: This paper proposes an Exchange-Based View of the value creation process. The Borrowing from marketing literature, the EBV advances that entrepreneurs and stakeholders are tied by exchange relationships, through which they co-create value by reciprocally making and realizing promises of value. Design/methodology/approach: Propositions are developed and offered to advance the role of exchange in the entrepreneurial value creation process. Findings: The authors conceptualize the enterprise as a system of exchange relationships between entrepreneurs and their stakeholders, thus proposing an exchange-based view of entrepreneurship. Originality/value: Such an account of the role of entrepreneurs and of their relationship with the stakeholders has meaningful implications for our understanding of the entrepreneurial tasks of opportunity recognition and exploitation.openPinelli M.; Lechner C.; Kraus S.; Liguori E.Pinelli, M.; Lechner, C.; Kraus, S.; Liguori, E

Type 2 Diabetes Mellitus and COVID-19: A Narrative Review

The pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has involved more than one hundred million individuals, including more than two million deaths. Diabetes represents one of the most prevalent chronic conditions worldwide and significantly increases the risk of hospitalization and death in COVID-19 patients. In this review, we discuss the prevalence, the pathophysiological mechanisms, and the outcomes of COVID-19 infection in people with diabetes. We propose a rationale for using drugs prescribed in patients with diabetes and some pragmatic clinical recommendations to deal with COVID-19 in this kind of patient

The PELskin project-part V: towards the control of the flow around aerofoils at high angle of attack using a self-activated deployable flap

During the flight of birds, it is often possible to notice that some of the primaries and covert feathers on the upper side of the wing pop-up under critical flight conditions, such as the landing approach or when stalking their prey (see Fig. 1) . It is often conjectured that the feathers pop up plays an aerodynamic role by limiting the spread of flow separation . A combined experimental and numerical study was conducted to shed some light on the physical mechanism determining the feathers self actuation and their effective role in controlling the flow field in nominally stalled conditions. In particular, we have considered a NACA0020 aerofoil, equipped with a flexible flap at low chord Reynolds numbers. A parametric study has been conducted on the effects of the length, natural frequency, and position of the flap. A configuration with a single flap hinged on the suction side at 70 % of the chord size c (from the leading edge), with a length of (Formula presented.) matching the shedding frequency of vortices at stall condition has been found to be optimum in delivering maximum aerodynamic efficiency and lift gains. Flow evolution both during a ramp-up motion (incidence angle from (Formula presented.) to (Formula presented.) with a reduced frequency of (Formula presented.), (Formula presented.) being the free stream velocity magnitude), and at a static stalled condition ((Formula presented.)) were analysed with and without the flap. A significant increase of the mean lift after a ramp-up manoeuvre is observed in presence of the flap. Stall dynamics (i.e., lift overshoot and oscillations) are altered and the simulations reveal a periodic re-generation cycle composed of a leading edge vortex that lift the flap during his passage, and an ejection generated by the relaxing of the flap in its equilibrium position. The flap movement in turns avoid the interaction between leading and trailing edge vortices when lift up and push the trailing edge vortex downstream when relaxing back. This cyclic behaviour is clearly shown by the periodic variation of the lift about the average value, and also from the periodic motion of the flap. A comparison with the experiments shows a similar but somewhat higher non-dimensional frequency of the flap oscillation. By assuming that the cycle frequency scales inversely with the boundary layer thickness, one can explain the higher frequencies observed in the experiments which were run at a Reynolds number about one order of magnitude higher than in the simulations. In addition, in experiments the periodic re-generation cycle decays after 3–4 periods ultimately leading to the full stall of the aerofoil. In contrast, the 2D simulations show that the cycle can become self-sustained without any decay when the flap parameters are accurately tuned

Treatments for hbv: A glimpse into the future

The hepatitis B virus is responsible for most of the chronic liver disease and liver cancer worldwide. As actual therapeutic strategies have had little success in eradicating the virus from hepatocytes, and as lifelong treatment is often required, new drugs targeting the various phases of the hepatitis B virus (HBV) lifecycle are currently under investigation. In this review, we provide an overview of potential future treatments for HBV