11,805 research outputs found

    M51 ULX-7: superorbital periodicity and constraints on the neutron star magnetic field

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    In this work, we explore the applicability of standard theoretical models of accretion to the observed properties of M51 ULX-7. The spin-up rate and observed X-ray luminosity are evidence of a neutron star with a surface magnetic field of 2-7 x 10(13) G, rotating near equilibrium. Analysis of the X-ray light curve of the system (Swift/XRT data) reveals the presence of a similar to 39 d superorbital period. We argue that the superorbital periodicity is due to disc precession, and that material is accreted on to the neutron star at a constant rate throughout it. Moreover, by attributing this modulation to the free precession of the neutron star we estimate a surface magnetic field strength of 3-4 x 10(13) G. The agreement of these two independent estimates provide strong constraints on the surface polar magnetic field strength of the NS

    Hierarchical Lattice Models of Hydrogen Bond Networks in Water

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    We develop a graph-based model of the hydrogen bond network in water, with a view towards quantitatively modeling the molecular-level correlational structure of the network. The networks are formed are studied by the constructing the model on two infinite-dimensional lattices. Our models are built \emph{bottom up}, based on microscopic information coming from atomistic simulations, and we show that the predictions of the model are consistent with known results from ab-initio simulations of liquid water. We show that simple entropic models can predict the correlations and clustering of local-coordination defects around tetrahedral waters observed in the atomistic simulations. We also find that orientational correlations between bonds are longer ranged than density correlations, and determine the directional correlations within closed loops and show that the patterns of water wires within these structures are also consistent with previous atomistic simulations. Our models show the existence of density and compressibility anomalies, as seen in the real liquid, and the phase diagram of these models is consistent with the singularity-free scenario previously proposed by Sastry and co-workers (Sastry et al, PRE 53, 6144 (1996)).Comment: 17 pages, published versio

    Molecular architecture of human polycomb repressive complex 2.

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    Polycomb Repressive Complex 2 (PRC2) is essential for gene silencing, establishing transcriptional repression of specific genes by tri-methylating Lysine 27 of histone H3, a process mediated by cofactors such as AEBP2. In spite of its biological importance, little is known about PRC2 architecture and subunit organization. Here, we present the first three-dimensional electron microscopy structure of the human PRC2 complex bound to its cofactor AEBP2. Using a novel internal protein tagging-method, in combination with isotopic chemical cross-linking and mass spectrometry, we have localized all the PRC2 subunits and their functional domains and generated a detailed map of interactions. The position and stabilization effect of AEBP2 suggests an allosteric role of this cofactor in regulating gene silencing. Regions in PRC2 that interact with modified histone tails are localized near the methyltransferase site, suggesting a molecular mechanism for the chromatin-based regulation of PRC2 activity.DOI:http://dx.doi.org/10.7554/eLife.00005.001

    Noninvasive Measurement of Dissipation in Colloidal Systems

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    According to Harada and Sasa [Phys. Rev. Lett. 95, 130602 (2005)], heat production generated in a non-equilibrium steady state can be inferred from measuring response and correlation functions. In many colloidal systems, however, it is a nontrivial task to determine response functions, whereas details about spatial steady state trajectories are easily accessible. Using a simple conditional averaging procedure, we show how this fact can be exploited to reliably evaluate average heat production. We test this method using Brownian dynamics simulations, and apply it to experimental data of an interacting driven colloidal system

    GFP for EM: Site-Specific Labeling of Proteins for Electron Microscopy

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    Individual differences in visual acuity and face matching ability

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    The visual acuity of the eyes varies outside the range of normal vision, requiring corrective lenses, but also within the normal range. This study investigated whether both types of variation relate to individual differences in face‐identity matching, considering this applied task requires perception of detail. Across two experiments, face‐matching accuracy correlated with variation in acuity when this fell outside the normal range of vision and was uncorrected with glasses or contact lenses. In contrast, variation in visual acuity within the normal range did not affect face‐matching accuracy, whereas matching accuracy at a given level of acuity could vary substantially. These results indicate that visual acuity is only a problem for occupations performing face‐identity matching when below‐normal acuity is not diagnosed or adequately corrected. In turn, these findings suggest that variation in acuity within the normal range is not a contributing factor to individual differences in face matching accuracy

    5d-5f Electric-multipole Transitions in Uranium Dioxide Probed by Non-resonant Inelastic X-ray Scattering

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    Non-resonant inelastic x ray scattering (NIXS) experiments have been performed to probe the 5d-5f electronic transitions at the uranium O(4,5) absorption edges in uranium dioxide. For small values of the scattering vector q, the spectra are dominated by dipole-allowed transitions encapsulated within the giant resonance, whereas for higher values of q the multipolar transitions of rank 3 and 5 give rise to strong and well-defined multiplet structure in the pre-edge region. The origin of the observed non-dipole multiplet structures is explained on the basis of many-electron atomic spectral calculations. The results obtained demonstrate the high potential of NIXS as a bulk-sensitive technique for the characterization of the electronic properties of actinide materials.Comment: Submitted to Physical Review Letters on 31 December 200
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