Clinical Outcomes of 0.018-Inch and 0.022-Inch Bracket Slot Using the ABO Objective Grading System

Objective: To determine if there is a significant difference in the clinical outcomes of cases treated with 0.018-inch brackets vs 0.022-inch brackets according to the American Board of Orthodontics (ABO) Objective Grading System (OGS). Materials and Methods: Treatment time and the ABO-OGS standards in alignment/rotations, marginal ridges, buccolingual inclination, overjet, occlusal relationships, occlusal contacts, interproximal contacts, and root angulations were used to compare clinical outcomes between a series of 828 consecutively completed orthodontic cases (2005–2008) treated in a university graduate orthodontic clinic with 0.018-inch- and 0.022-inch-slot brackets. Results: A two-sample t-test showed a significantly shorter treatment time and lower ABO-OGS score in four categories (alignment/rotations, marginal ridges, overjet, and root angulations), as well as lower total ABO-OGS total score, with the 0.018-inch brackets. The ANCOVA—adjusting for covariants of discrepancy index, age, gender, and treatment time—showed that the 0.018-inch brackets scored significantly lower than the 0.022-inch brackets in both the alignment/rotations category and total ABO-OGS score. Conclusions: There were statistically, but not clinically, significant differences in treatment times and in total ABO-OGS scores in favor of 0.018-inch brackets as compared with the 0.022-inch brackets in a university graduate orthodontic clinic (2005–2008)

Benefactive and substitutive applicatives in Bemba

Benefactive applicative constructions can encode a range of different meanings, including notably recipient, substitutive and plain benefactive readings, which are often distinguished in cross-linguistic studies. In Bantu languages, this distinction has not received much attention, in part because most Bantu languages do not formally distinguish between different readings of benefactive applicatives. In Bemba (Bantu M42, Zambia), by contrast, substitutive applicatives, where the action of the verb is performed by the agent instead of, on behalf of, or in place of someone else, are formally marked by applicative morphology in addition to a post-verbal clitic -ko, based on a grammaticalised locative demonstrative clitic. The paper provides a detailed discussion of the construction and proposes that the interpretation of substitutive applicatives results from the interaction of abstract applicative and locative semantics and depends on underlying metaphors of spatial and abstract location. Bemba benefactive applicatives thus provide an illustration of the complex function and interpretation of Bantu applicatives and locative markers more widely. The construction is interesting from a historical- comparative and typological perspective because of the particular grammaticalisation process from a locative source involved in the historical development of the construction, and because substitution is marked in addition to applicative marking

A comparative study of depression in Bantu, Khoisan and Chinese Wu – laryngeal settings and feature specifications

This paper aims to provide an overview of our current understanding of depressors by offering a comparative perspective of the types of depressors from Bantu, Khoisan and Chinese Wu. Depressor effects in Bantu/Khoisan, on the one hand, and Chinese, on the other, are hardly dealt with together leaving a more holistic approach untapped. This paper begins to bridge that gap by bringing together current findings to establish the full scope of depressor effects, from which future analyses can then build on. It is systematically observed that depressors in these languages are not restricted to voicing only. Rather, they range from voiced and breathy sounds – the most unmarked – to voiceless unaspirated sounds and even voiceless aspirated sounds as the most marked depressor type. The expansion of depressors to voiceless aspirated sounds is particularly interesting, since these sounds are traditionally assumed to correlate with a high pitch which is characteristic of high tone. Thus, the laryngeal configurations for voiceless depressors are examined and compared between Bantu, Khoisan and Chinese Wu. Proposed feature analyses for depressors are also discussed and compared.Keywords: depressors, Bantu, Khoisan, Chinese Wu, laryngeal specificatio

Cardiac hemangioma of the right atrium in a neonate : fetal management and expedited surgical resection

Cardiac hemangioma is a rare tumor with a reported incidence of 1-2%. We describe the case of a neonate with a right atrial mass that was diagnosed prenatally. The fetus developed a supraventricular tachycardia and was delivered by cesarean section in the 35th week of gestation. The infant underwent surgery after 24 hours to remove the mass which was diagnosed as a cardiac capillary-cavernous hemangioma.peer-reviewe

Mental representation of tonal spreading in Bemba: Evidence from elicited production and perception

Previous research has shown that listeners from tonal languages are better at processing tone compared to speakers from non-tonal languages. However, most of this research has tested Asian tone languages, particularly those which have many tonal contrasts and a dense tone-to-syllable association. In this paper we investigate the mental representation of derived tones in Bemba, a Bantu language that has a two-way tone contrast but which shows robust tone spreading patterns. Specifically, we test ternary high-tone spreading, a process that is unique from a phonological perspective. In a production task we test whether ternary spread can be extended to non-words. We complement this with an AX discrimination task comparing binary vs ternary spread, which are phonologically contrastive, on the one hand, with a tonally similarly salient but non-phonologically relevant contrast, on the other. We show that in both the production and percep- tion of non-words, ternary spread is distinct from binary spread, suggesting that derived tone is equally mentally represented as lexical tone is in Asian tone languages

Phrasal phonology in Copperbelt Bemba

Copperbelt Bemba exhibits several rightward spreading tonal processes which are sensitive to prosodic phrase structure. The rightmost H tone in a word will undergo unbounded spreading if the word is final in a phonological phrase (phi). In an intonational phrase consisting of several single-word phi's, the rightmost H in the first word will spread through all following toneless phi's. From a rule-based perspective, this can only be accounted for by positing mutually feeding iterative rules, as a single H-tone spreading rule cannot account for the long-distance spreading. Rather, a second rule that spreads a H from the final mora of one word onto the initial mora of the following word is required, as a bridge to further unbounded spreading. Three phrase-sensitive OT constraints are proposed to account for H-tone spreading between words. One is of the domain-juncture variety, requiring the specification of two separate prosodic domains

Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation

The mechanisms involved in the regulation of mammalian sperm motility are not well understood. Calcium ions (Ca(2+)) have been suggested to play a key role in the maintenance of motility; nevertheless, how Ca(2+) modulates this process has not yet been completely characterized. Ca(2+) can bind to calmodulin and this complex regulates the activity of multiple enzymes, including Ca(2+)/calmodulin-dependent protein kinases (CaM kinases). Results from this study confirmed that the presence of Ca(2+) in the incubation medium is essential for maintaining human sperm motility. The involvement of CaM kinases in Ca(2+) regulation of human sperm motility was evaluated using specific inhibitors (KN62 and KN93) or their inactive analogues (KN04 and KN92 respectively). Sperm incubation in the presence of KN62 or KN93 led to a progressive decrease in the percentage of motile cells; in particular, incubation with KN62 also reduced sperm motility parameters. These inhibitors did not alter sperm viability, protein tyrosine phosphorylation or the follicular fluid-induced acrosome reaction; however, KN62 decreased the total amount of ATP in human sperm. Immunological studies showed that Ca(2+)/calmodulin-dependent protein kinase IV (CaMKIV) is present and localizes to the human sperm flagellum. Moreover, CaMKIV activity increases during capacitation and is inhibited in the presence of KN62. This report is the first to demonstrate the presence of CaMKIV in mammalian sperm and suggests the involvement of this kinase in the regulation of human sperm motility.Fil: Marin Briggiler, Clara Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Jha, Kula N.. University of Virginia; Estados UnidosFil: Chertihin, Olga. University of Virginia; Estados UnidosFil: Buffone, Mariano Gabriel. Laboratorio de Estudios en Reproducción; ArgentinaFil: Herr, John C,. University of Virginia; Estados UnidosFil: Vazquez, Monica Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Visconti, Pablo E.. University of Massachussets; Estados Unido