588 research outputs found
Delayed Sciatic Nerve Injury Resulting From Myositis Ossificans Traumatica
A motorcyclist sustained multipleĂą system trauma, including a left buttock hematoma requiring decompression and evacuation. Presentation for severe hip pain and lower extremity weakness was delayed. Imaging revealed myositis ossificans traumatica compressing the sciatic nerve in the buttock. The patient underwent sciatic nerve decompression with resection of heterotopic calcification, resulting in improvement in pain and left lower extremity function. This case illustrates the contrast in differential diagnosis of peripheral nerve injury immediately posttrauma and that occurring in a slow, delayed fashion posttrauma. Myositis ossificans may be an underrecognized complication of trauma but should be considered in cases of delayed peripheral nerve injury after trauma.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147088/1/pmrj484.pd
Search for microwave emission from ultrahigh energy cosmic rays
We present a search for microwave emission from air showers induced by
ultrahigh energy cosmic rays with the microwave detection of air showers
experiment. No events were found, ruling out a wide range of power flux and
coherence of the putative emission, including those suggested by recent
laboratory measurements.Comment: 5 pages, 3 figure
Influence of acetaminophen and ibuprofen on in vivo patellar tendon adaptations to knee extensor resistance exercise in older adults
Millions of older individuals consume acetaminophen or ibuprofen daily and these same individuals are encouraged to participate in resistance training. Several in vitro studies suggest that cyclooxygenase-inhibiting drugs can alter tendon metabolism and may influence adaptations to resistance training. Thirty-six individuals were randomly assigned to a placebo (67 ± 2 yr old), acetaminophen (64 ± 1 yr old; 4,000 mg/day), or ibuprofen (64 ± 1 yr old; 1,200 mg/day) group in a double-blind manner and completed 12 wk of knee extensor resistance training. Before and after training in vivo patellar tendon properties were assessed with MRI [cross-sectional area (CSA) and signal intensity] and ultrasonography of patellar tendon deformation coupled with force measurements to obtain stiffness, modulus, stress, and strain. Mean patellar tendon CSA was unchanged (P > 0.05) with training in the placebo group, and this response was not influenced with ibuprofen consumption. Mean tendon CSA increased with training in the acetaminophen group (3%, P < 0.05), primarily due to increases in the mid (7%, P < 0.05) and distal (8%, P < 0.05) tendon regions. Correspondingly, tendon signal intensity increased with training in the acetaminophen group at the mid (13%, P < 0.05) and distal (15%, P = 0.07) regions. When normalized to pretraining force levels, patellar tendon deformation and strain decreased 11% (P < 0.05) and stiffness, modulus, and stress were unchanged (P > 0.05) with training in the placebo group. These responses were generally uninfluenced by ibuprofen consumption. In the acetaminophen group, tendon deformation and strain increased 20% (P < 0.05) and stiffness (â17%, P < 0.05) and modulus (â20%, P < 0.05) decreased with training. These data suggest that 3 mo of knee extensor resistance training in older adults induces modest changes in the mechanical properties of the patellar tendon. Over-the-counter doses of acetaminophen, but not ibuprofen, have a strong influence on tendon mechanical and material property adaptations to resistance training. These findings add to a growing body of evidence that acetaminophen has profound effects on peripheral tissues in humans
Predicting prognosis for adults with depression using individual symptom data:a comparison of modelling approaches
BACKGROUND: This study aimed to develop, validate and compare the performance of models predicting post-treatment outcomes for depressed adults based on pre-treatment data. METHODS: Individual patient data from all six eligible randomised controlled trials were used to develop (k = 3, n = 1722) and test (k = 3, n = 918) nine models. Predictors included depressive and anxiety symptoms, social support, life events and alcohol use. Weighted sum scores were developed using coefficient weights derived from network centrality statistics (models 1-3) and factor loadings from a confirmatory factor analysis (model 4). Unweighted sum score models were tested using elastic net regularised (ENR) and ordinary least squares (OLS) regression (models 5 and 6). Individual items were then included in ENR and OLS (models 7 and 8). All models were compared to one another and to a null model (mean post-baseline Beck Depression Inventory Second Edition (BDI-II) score in the training data: model 9). Primary outcome: BDI-II scores at 3-4 months. RESULTS: Models 1-7 all outperformed the null model and model 8. Model performance was very similar across models 1-6, meaning that differential weights applied to the baseline sum scores had little impact. CONCLUSIONS: Any of the modelling techniques (models 1-7) could be used to inform prognostic predictions for depressed adults with differences in the proportions of patients reaching remission based on the predicted severity of depressive symptoms post-treatment. However, the majority of variance in prognosis remained unexplained. It may be necessary to include a broader range of biopsychosocial variables to better adjudicate between competing models, and to derive models with greater clinical utility for treatment-seeking adults with depression
The MIDAS telescope for microwave detection of ultra-high energy cosmic rays
We present the design, implementation and data taking performance of the
MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view
imaging telescope designed to detect microwave radiation from extensive air
showers induced by ultra-high energy cosmic rays. This novel technique may
bring a tenfold increase in detector duty cycle when compared to the standard
fluorescence technique based on detection of ultraviolet photons. The MIDAS
telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera,
instrumented with feed horns operating in the commercial extended C-Band (3.4
-- 4.2 GHz). A self-trigger capability is implemented in the digital
electronics. The main objectives of this first prototype of the MIDAS telescope
- to validate the telescope design, and to demonstrate a large detector duty
cycle - were successfully accomplished in a dedicated data taking run at the
University of Chicago campus prior to installation at the Pierre Auger
Observatory.Comment: 13 pages, 18 figure
ĐŃĐŽ ŃŃĐœĐŽĐ°ĐŒĐ”ĐœŃĐ°Đ»ŃĐœĐžŃ ĐŽĐŸŃĐ»ŃĐŽĐ¶Đ”ĐœŃ ĐŽĐŸ ĐșĐŸĐŒĐ”ŃŃŃĐ°Đ»ŃĐ·Đ°ŃŃŃ ŃДзŃĐ»ŃŃĐ°ŃŃĐČ: ĐŽĐŸŃĐČŃĐŽ Ń Đ·Đ°ĐČĐŽĐ°ĐœĐœŃ ĐĐĐ ĐŁĐșŃĐ°ŃĐœĐž
ĐŁ ŃŃĐ°ŃŃŃ ĐŽĐ°ĐœĐŸ ĐșĐŸŃĐŸŃĐșĐžĐč ĐŸĐłĐ»ŃĐŽ ĐŽĐ”ŃĐșĐžŃ
ĐœĐ°ŃĐșĐŸĐČĐŸ-ŃĐ”Ń
ĐœŃŃĐœĐžŃ
ŃĐŸĐ·ŃĐŸĐ±ĐŸĐș, ŃĐŸ ĐČĐžĐșĐŸĐœĐ°ĐœŃ ĐČ ĐŸŃŃĐ°ĐœĐœŃ ŃĐŸĐșĐž ĐČ ŃŃŃĐ°ĐœĐŸĐČĐ°Ń
ĐĐĐ ĐŁĐșŃĐ°ŃĐœĐž Ń ĐČжД Đ·ĐœĐ°ĐčŃлО ĐżŃĐ°ĐșŃĐžŃĐœĐ” Đ·Đ°ŃŃĐŸŃŃĐČĐ°ĐœĐœŃ Đ°Đ±ĐŸ ĐłĐŸŃĐŸĐČŃ ĐŽĐŸ ŃĐœĐœĐŸĐČĐ°ŃŃĐčĐœĐŸĐłĐŸ ĐČĐżŃĐŸĐČĐ°ĐŽĐ¶Đ”ĐœĐœŃ. ĐŠŃ ŃĐŸĐ·ŃĐŸĐ±ĐșĐž пДŃĐ”ĐșĐŸĐœŃŃŃŃ Ń ŃĐŸĐŒŃ, ŃĐŸ ĐœĐ°ŃĐșĐ° ĐŁĐșŃĐ°ŃĐœĐž збДŃŃĐłĐ°Ń ĐżĐŸŃŃĐ¶ĐœĐžĐč ĐżĐŸŃĐ”ĐœŃŃĐ°Đ», ŃĐșĐžĐč ĐŒĐŸĐ¶Đ” ĐżĐŸĐČĐœŃŃŃŃ ŃДалŃĐ·ŃĐČĐ°ŃĐžŃŃ ĐżŃĐž ĐœĐ°Đ»Đ”Đ¶ĐœŃĐč ŃŃĐœĐ°ĐœŃĐŸĐČŃĐč ĐżŃĐŽŃŃĐžĐŒŃŃ Đ· Đ±ĐŸĐșŃ ĐŽĐ”ŃжаĐČĐž Ń ŃŃĐČĐŸŃĐ”ĐœĐœŃ ŃĐżŃĐžŃŃлОĐČĐŸĐłĐŸ ŃĐœĐœĐŸĐČĐ°ŃŃĐčĐœĐŸĐłĐŸ ĐșĐ»ŃĐŒĐ°ŃŃ, ŃĐŸ ĐŽĐ°ŃŃŃ ĐŒĐŸĐ¶Đ»ĐžĐČŃŃŃŃ ĐœĐ°ŃĐșĐŸĐČŃŃĐŒ Đ·Đ°ŃĐŸĐ±Đ»ŃŃĐž Đ·ĐœĐ°ŃĐœŃ ĐżĐŸĐ·Đ°Đ±ŃЎжДŃĐœŃ ĐșĐŸŃŃĐž ŃĐČĐŸŃŃ ĐżŃĐžĐșĐ»Đ°ĐŽĐœĐŸŃ ĐŽŃŃĐ»ŃĐœŃŃŃŃ.Đ ŃŃĐ°ŃŃĐ” ĐżŃĐžĐČĐ”ĐŽĐ”Đœ ĐșŃĐ°ŃĐșĐžĐč ĐŸĐ±Đ·ĐŸŃ ĐœĐ”ĐșĐŸŃĐŸŃŃŃ
ĐœĐ°ŃŃĐœĐŸ-ŃĐ”Ń
ĐœĐžŃĐ”ŃĐșĐžŃ
ŃĐ°Đ·ŃĐ°Đ±ĐŸŃĐŸĐș, ĐșĐŸŃĐŸŃŃĐ” ĐČŃĐżĐŸĐ»ĐœĐ”ĐœŃ ĐČ ĐżĐŸŃĐ»Đ”ĐŽĐœĐžĐ” ĐłĐŸĐŽŃ ĐČ ŃŃŃĐ”Đ¶ĐŽĐ”ĐœĐžŃŃ
ĐĐĐ ĐŁĐșŃĐ°ĐžĐœŃ Đž ŃжД ĐœĐ°ŃлО ĐżŃĐ°ĐșŃĐžŃĐ”ŃĐșĐŸĐ” ĐżŃĐžĐŒĐ”ĐœĐ”ĐœĐžĐ” Đ»ĐžĐ±ĐŸ ĐłĐŸŃĐŸĐČŃ Đș ĐžĐœĐœĐŸĐČĐ°ŃĐžĐŸĐœĐœĐŸĐŒŃ ĐČĐœĐ”ĐŽŃĐ”ĐœĐžŃ. ĐŃĐž ŃĐ°Đ·ŃĐ°Đ±ĐŸŃĐșĐž ŃбДжЎаŃŃ ĐČ ŃĐŸĐŒ, ŃŃĐŸ ĐœĐ°ŃĐșĐ° ĐŁĐșŃĐ°ĐžĐœŃ ŃĐŸŃ
ŃĐ°ĐœŃĐ”Ń ĐŒĐŸŃĐœŃĐč ĐżĐŸŃĐ”ĐœŃОал, ĐșĐŸŃĐŸŃŃĐč ĐŒĐŸĐ¶Đ”Ń ĐżĐŸĐ»ĐœĐŸŃŃŃŃ ŃĐ”Đ°Đ»ĐžĐ·ĐŸĐČĐ°ŃŃŃŃ ĐżŃĐž ĐœĐ°ĐŽĐ»Đ”Đ¶Đ°ŃĐ”Đč ŃĐžĐœĐ°ĐœŃĐŸĐČĐŸĐč ĐżĐŸĐŽĐŽĐ”ŃжĐșĐ” ŃĐŸ ŃŃĐŸŃĐŸĐœŃ ĐłĐŸŃŃĐŽĐ°ŃŃŃĐČĐ° Đž ŃĐŸĐ·ĐŽĐ°ĐœĐžĐž Đ±Đ»Đ°ĐłĐŸĐżŃĐžŃŃĐœĐŸĐłĐŸ ĐžĐœĐœĐŸĐČĐ°ŃĐžĐŸĐœĐœĐŸĐłĐŸ ĐșĐ»ĐžĐŒĐ°ŃĐ°, ŃŃĐŸ ĐżĐŸĐ·ĐČĐŸĐ»ĐžŃ ŃŃĐ”ĐœŃĐŒ Đ·Đ°ŃабаŃŃĐČĐ°ŃŃ Đ·ĐœĐ°ŃĐžŃДлŃĐœŃĐ” ĐČĐœĐ”Đ±ŃЎжДŃĐœŃĐ” ŃŃДЎŃŃĐČĐ° ŃĐČĐŸĐ”Đč ĐżŃĐžĐșĐ»Đ°ĐŽĐœĐŸĐč ĐŽĐ”ŃŃДлŃĐœĐŸŃŃŃŃ.A brief review of some science & technology developments is contained, accomplished in recent years in institutions of the National Academy of Sciences (NAS) of Ukraine, already used or ready for innovation-specific applications. These developments can assure that science in Ukraine could preserve the powerful capacity that can be fully utilized given proper financial support from the state and fostering favorable innovation climate, which will allow scientists to earn good off-budget money by applied activities
Effectiveness of counseling for anxiety and depression in mothers of children ages 0-30 months by community workers in Karachi, Pakistan: a quasi experimental study
<p>Abstract</p> <p>Background</p> <p>The prevalence of anxiety/depression is quite high during the perinatal period but unfortunately its detection and treatment have been less than satisfactory. Moreover, many women are reluctant to take pharmacotherapy for fear of excretion of drugs into their breast milk. This study assesses the effectiveness of counseling from minimally trained community health workers in reducing anxiety/depression, the rate of recurrence and the interval preceding recurrence in women during first two and a half years after childbirth.</p> <p>Methods</p> <p>In a quasi-experimental study, community women from two under-privileged communities were trained in data gathering, teaching healthy child-rearing practices, basic counseling skills, and screening for anxiety/depression by using an indigenously developed questionnaire, the Aga Khan University Anxiety and Depression Scale (AKUADS). The diagnosis was further confirmed by a clinical psychologist using DSM IV criteria. After obtaining consent, 420 women were screened and 102 were identified as having anxiety/depression. Screening was carried out after 1, 2, 6, 12, 18, 24 and 30 months of a live birth. Only 62 out of 102 agreed to be counseled and received eight weekly sessions. AKUADS was re-administered at 4 weeks and 8 weeks after the beginning of counseling; this was followed by the clinical psychologist's interview for confirmation of response. After recovery, screening was continued every 3 months for detection of recurrence throughout the study period. Out of the women who had declined counseling 12 agreed to retake AKUADS after 4 and 8 weeks of diagnosis. Independent samples t-test, chi-square test, Repeated Measures ANOVA and Kaplan Meier technique were used for the analysis.</p> <p>Results</p> <p>A significant decline in level of anxiety/depression was found in both the counseled and the non-counseled groups at 4 and 8 weeks (p-value < 0.001) but the counseled group fared better than the non-counseled for recovery, reduction in the rate of recurrence and increase in the duration before relapse.</p> <p>Conclusions</p> <p>As our results cannot be generalized; further studies need to be carried out, to assess the benefit of incorporating minimal counseling skills in the training of community health workers.</p
The Pierre Auger Observatory III: Other Astrophysical Observations
Astrophysical observations of ultra-high-energy cosmic rays with the Pierre
Auger ObservatoryComment: Contributions to the 32nd International Cosmic Ray Conference,
Beijing, China, August 201
Highlights from the Pierre Auger Observatory
The Pierre Auger Observatory is the world's largest cosmic ray observatory.
Our current exposure reaches nearly 40,000 km str and provides us with an
unprecedented quality data set. The performance and stability of the detectors
and their enhancements are described. Data analyses have led to a number of
major breakthroughs. Among these we discuss the energy spectrum and the
searches for large-scale anisotropies. We present analyses of our X
data and show how it can be interpreted in terms of mass composition. We also
describe some new analyses that extract mass sensitive parameters from the 100%
duty cycle SD data. A coherent interpretation of all these recent results opens
new directions. The consequences regarding the cosmic ray composition and the
properties of UHECR sources are briefly discussed.Comment: 9 pages, 12 figures, talk given at the 33rd International Cosmic Ray
Conference, Rio de Janeiro 201
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