Penerapan Kampanye Penggalangan Dana oleh Perusahaan Penyiaran Televisi untuk Mendukung Kegiatan Kemanusiaan (Studi Deskriptif Kulitatif Program Jembatan Asa Sctv)

Turut berkontribusi terhadap masa depan masyarakat agar menjadi lebih baik merupakan salah satu kewajiban Perusahaan, tak terkecuali Perusahaan yang bergerak dalam bidang industri penyiaran. Penelitian ini membahas kampanye penggalangan dana oleh PT Surya Citra Televisi (SCTV) melalui program Jembatan Asa, sebuah program kemanusiaan untuk membangun jembatan rusak di berbagai daerah di Indonesia. Tujuan penelitian ini adalah untuk mengetahui penerapan kampanye penggalangan dana kemanusiaan Program Jembatan Asa oleh SCTV dengan menggunakan model kampanye Nowak dan Warneryd. Pada model ini terdapat delapan elemen kampanye yang harus diperhatikan: efek yang diharapkan; persaingan komunikasi; obyek komunikasi; populasi target dan kelompok penerima; saluran; pesan; komunikator/pengirim pesan; efek yang dicapai. Pendekatan penelitian yang digunakan adalah kualitatif, dengan sifat penelitian deskriptif. Prosedur pengumpulan data melalui dokumentasi iklan dan berita serta wawancara mendalam dari key informan, yakni Ketua Penyelenggara program CSR Jembatan Asa, Manajer Produksi Berita, Produser Program Liputan 6 dan Video Journalist di Divisi Pemberitaan SCTV. Hasil dan analisis temuan data memperlihatkan bahwa kampanye dilakukan dengan menggandeng stakeholder internal SCTV yaitu departemen pemberitaan, programming, promosi, IT dan media online www.liputan6.com. Sedangkan dari pihak eksternal dilakukan kerja sama dengan Yayasan Relawan Kampung dan Kementerian Sosial Republik Indonesia. Target khalayak yang dituju mengalami Perubahan dari awalnya masyarakat ekonomi kelas A,B,C, diperluas menjadi kelas D dan E, serta kaum muda yang memanfaatkan media online dan media sosial dalam keseharian. Media yang digunakan dalam kampanye terdiri dari traditional media dan new media. Traditional media yang digunakan yaitu program berita Liputan 6, program infotainmen Was-was dan Halo Selebriti, serta program hiburan Inbox yang semuanya tayang di SCTV. Kampenye melalui new media, dilakukan dengan cara publikasi di media online, www.liputan6.com dan www.sctv.co.id. Sedangkan publikasi media sosial dilakukan melalui facebook https://www.facebook.com/Surya.Citra.TV dan twitter @SCTV_. Dengan menggunakan kampanye tersebut, SCTV mampu memperoleh sumbangan dana masyarakat sebesar Rp 4.546.241.368, yang digunakan untuk membangun 10 jembatan, melebihi target awal kampanye yang direncanakan hanya membangun 3 jembata

Cyclodextrin-Based Nanofibers and Membranes: Fabrication, Properties and Applications

Cyclodextrin (CD)-based electrospun nanofibers have become critical role players in the water treatment arena due to their high porosities, small diameters, high surface area-to-volume ratio and other unique properties they exhibit. Investigations demonstrate that nanofibers containing CD molecules can be facially blended with other polymeric species and/or photocatalytic and magnetic nanoparticles to enhance their rates of adsorption, inclusion complexation and selective photodegradation. These properties make them excellent candidates for the removal of water pollutants. On the other hand, the electrospinning process has become the method of choice in the fabrication of various types of CD nanofibrous mats due to its versatility, cost-effectiveness and its potential for the mass production of uniform nanofibers. CDs and CD-derivatives have also found application in membrane technologies, particularly in mixed matrix and thin film composite membranes. CD-blended membranes display improved performances in terms of selectivity, rejection, permeation and flux with reduced fouling propensities and can be used for drinking water purification and removal of emerging micropollutants. This chapter critically reviews CD-based electrospun nanofibers looking at their production, characterization methods and various applications. The use of CDs as membrane materials and how they can be fully explored in water treatment are also investigated

State-of-the-art of design and operation of power systems with large amounts of wind power, summary of IEA Wind collaboration

An international forum for exchange of knowledge of power system impacts of wind power has been formed under the IEA Implementing Agreement on Wind Energy. The task “Design and Operation of Power Systems with Large Amounts of Wind Power” is analysing existing case studies from different power systems.There are a multitude of studies made and ongoing related to cost of wind integration. However, the results are not easy to compare. This paper summarises the results from 15 case studies

Identifying brain changes related to cognitive aging using VBM and visual rating scales

Aging is often associated with changes in brain structures as well as in cognitive functions. Structural changes can be visualized with Magnetic Resonance Imaging (MRI) using voxel-based grey matter morphometry (VBM) and visual rating scales to assess atrophy level. Several MRI studies have shown that possible neural correlates of cognitive changes can be seen in normal aging. It is still not fully understood how cognitive function as measured by tests and demographic factors are related to brain changes in the MRI. We recruited 55 healthy elderly subjects aged 50–79 years. A battery of cognitive tests was administered to all subjects prior to MRI scanning. Our aim was to assess correlations between age, sex, education, cognitive test performance, and the said two MRI-based measures. Our results show significant differences in VBM grey matter volume for education level (≤ 12 vs. > 12 years), with a smaller amount of grey matter volume in subjects with lower educational levels, and for age in interaction with education, indicating larger grey matter volume for young, higher educated adults. Also, grey matter volume was found to be correlated with working memory function (Digit Span Backward). Furthermore, significant positive correlations were found between visual ratings and both age and education, showing larger atrophy levels with increasing age and decreasing level of education. These findings provide supportive evidence that MRI-VBM detects structural differences for education level, and correlates with educational level and age, and working memory task performance.</p

Crosswalk study on blood collection-tube types for Alzheimer's disease biomarkers

Introduction: Blood-based Alzheimer's disease (AD) biomarkers show promise, but pre-analytical protocol differences may pose problems. We examined seven AD blood biomarkers (amyloid beta [ A β ] 42 , A β 40 , phosphorylated tau [ p - ta u 181 , total tau [t-tau], neurofilament light chain [NfL], A β 42 40 , and p - ta u 181 A β 42 ) in three collection tube types (ethylenediaminetetraacetic acid [EDTA] plasma, heparin plasma, serum). Methods: Plasma and serum were obtained from cerebrospinal fluid or amyloid positron emission tomography-positive and -negative participants (N = 38) in the Wisconsin Registry for Alzheimer's Prevention. We modeled AD biomarker values observed in EDTA plasma versus heparin plasma and serum, and assessed correspondence with brain amyloidosis. Results: Results suggested bias due to tube type, but crosswalks are possible for some analytes, with excellent model fit for NfL ( R 2 = 0.94), adequate for amyloid ( R 2 = 0.40-0.69), and weaker for t-tau ( R 2 = 0.04-0.42) and p - ta u 181 ( R 2 = 0.22-0.29). Brain amyloidosis differentiated several measures, especially EDTA plasma pTa u 181 A β 42 ( d = 1.29). Discussion: AD biomarker concentrations vary by tube type. However, correlations for some biomarkers support harmonization across types, suggesting cautious optimism for use in banked blood

Effect of Pathway-Specific Polygenic Risk Scores for Alzheimer's Disease (AD) on Rate of Change in Cognitive Function and AD-Related Biomarkers Among Asymptomatic Individuals

BACKGROUND: Genetic scores for late-onset Alzheimer's disease (LOAD) have been associated with preclinical cognitive decline and biomarker variations. Compared with an overall polygenic risk score (PRS), a pathway-specific PRS (p-PRS) may be more appropriate in predicting a specific biomarker or cognitive component underlying LOAD pathology earlier in the lifespan. OBJECTIVE: In this study, we leveraged longitudinal data from the Wisconsin Registry for Alzheimer's Prevention and explored changing patterns in cognition and biomarkers at various age points along six biological pathways. METHODS: PRS and p-PRSs with and without APOE were constructed separately based on the significant SNPs associated with LOAD in a recent genome-wide association study meta-analysis and compared to APOE alone. We used a linear mixed-effects model to assess the association between PRS/p-PRSs and cognitive trajectories among 1,175 individuals. We also applied the model to the outcomes of cerebrospinal fluid biomarkers in a subset. Replication analyses were performed in an independent sample. RESULTS: We found p-PRSs and the overall PRS can predict preclinical changes in cognition and biomarkers. The effects of PRS/p-PRSs on rate of change in cognition, amyloid-β, and tau outcomes are dependent on age and appear earlier in the lifespan when APOE is included in these risk scores compared to when APOE is excluded. CONCLUSION: In addition to APOE, the p-PRSs can predict age-dependent changes in amyloid-β, tau, and cognition. Once validated, they could be used to identify individuals with an elevated genetic risk of accumulating amyloid-β and tau, long before the onset of clinical symptoms