311 research outputs found

    European society of urogenital radiology (ESUR) guidelines: MR imaging of pelvic endometriosis

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    Endometriosis is a common gynaecological condition of unknown aetiology that primarily affects women of reproductive age. The accepted first-line imaging modality is pelvic ultrasound. However, magnetic resonance imaging (MRI) is increasingly performed as an additional investigation in complex cases and for surgical planning. There is currently no international consensus regarding patient preparation, MRI protocols or reporting criteria. Our aim was to develop clinical guidelines for MRI evaluation of pelvic endometriosis based on literature evidence and consensus expert opinion. This work was performed by a group of radiologists from the European Society of Urogenital Radiology (ESUR), experts in gynaecological imaging and a gynaecologist expert in methodology. The group discussed indications for MRI, technical requirements, patient preparation, MRI protocols and criteria for the diagnosis of pelvic endometriosis on MRI. The expert panel proposed a final recommendation for each criterion using Oxford Centre for Evidence Based Medicine (OCEBM) 2011 levels of evidence.info:eu-repo/semantics/publishedVersio

    Perioperative morbidity of radical trachelectomy with lymphadenectomy in early-stage cervical cancer: a French prospective multicentric cohort.

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    The aim of this study was to determine the predictive factors of postoperative morbidity of patients who have undergone a radical trachelectomy (RT) for early-stage cervical cancer and to assess the oncologic outcomes. We retrospectively analysed the data of 2 prospective trials on sentinel node biopsy for cervical cancer (SENTICOL I and II). Patients having a RT for early-stage cervical cancer with negative sentinel lymph node and safe margins, were included. Forty-nine patients met the inclusion criteria. Forty-five patients had a laparoscopic-assisted vaginal technique and 4 patients a total laparoscopic technique. The median age was 32 years (range, 22-46 years). 83.7% of patients had a stage IB1 disease. There were 63.3% squamous cell carcinomas and 34.7% adenocarcinomas. The median follow-up was 46 months (range, 1-85 months). Two patients (3.3%) had a severe postoperative complication (Clavien-Dindo ≄III and/or CTCAE ≄3). The main postoperative complications were urinary (28.6%), lymphovascular (26.5%) and neurologic (14.3%). On a multivariate analysis, postoperative complications were significantly associated with history of pelvic surgery and IB1 International Federation of Gynecology and Obstetrics stage. Inclusion in high surgical skills centers decrease the risk of postoperative complications. During the follow-up, 3 patients (6.1%) had a local recurrence and one patient died from a breast cancer. Between group with complications and group without any complications, overall survival and recurrence-free survival did not significantly differ at 5-year of follow-up. RT has few severe postoperative complications and appears as a safe alternative to spare fertility of young patients. To guarantee best surgical outcomes, patients should be referred to expert center

    Expansion of elevational range in a forest pest: Can parasitoids track their hosts?

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    We are thankful to Karim Senhadji and Ramon Ruiz-Puche for their help during the field work, and to Sara Garcia Morato for her contribution to quantifying rates of parasitism in PPM clutches at the laboratory. Two anonymous referees contributed to improve the manuscript. This study was supported by projects PROPINOL (PN22/2008), GESBOME (P06-RNM-1890) from Junta de Andalucia, REMEDINAL TE-CM (S2018/EMT-4338) from Comunidad de Madrid, ADAPTAMED (LIFE14 CCA/ES/000612) from LIFE program, and GILES (PCIN-2016-150) from the ERANET-LAC H2020 Programme.Gradients in elevation impose changes in environmental conditions, which in turn modulate species distribution and abundance as well as the interactions they maintain. Along the gradient, interacting species (e.g., predators, parasitoids) can respond to changes in different ways. This study aims to investigate how egg parasitism of a forest pest, the pine processionary moth (PPM), Thaumetopoea pityocampa, vary along an elevational gradient (190-2000 m.a.s.l.) in a mountain range of SE Spain, including areas of recent elevational expansion, for a seven years period (2008-2014). We used generalized linear mixed models to ascertain the effect of both elevation and the winter North Atlantic Oscillation (NAO) index (a proxy of interannual climatic conditions) on the rate of parasitism, and the occurrence probabilities of two parasitoid species: a PPM specialist and a generalist species. Since four pine species are stratified along the elevational gradient, we repeated all the analyses separately for lowlands (190-1300 m. a.s.l.) and uplands (1350-2000 m. a.s.l.). Results showed a decrease in both parasitism rate and probability of occurrence of the two main parasitoid species with elevation, although decline was more severe for the specialist species. The effect of elevation was more conspicuous and intense in uplands than in lowlands. Positive NAO winter values, associated with cold and dry winters, reduced the rate of parasitism and the probability of occurrence of the two main parasitoid species-but particularly for the generalist species-as elevation increases. In a context of climate warming, it is crucial to mitigate PPM elevational and latitudinal expansion. Increasing tree diversity at the PPM expansion areas may favor the establishment of parasitoids, which could contribute to synchronizing host- parasitoid interactions and minimize the risk of PPM outbreaks.Junta de Andalucia PN22/2008REMEDINAL TE-CM from Comunidad de Madrid S2018/EMT-4338ADAPTAMED from LIFE program LIFE14 CCA/ES/000612GILES from the ERANET-LAC H2020 Programme PCIN-2016-150Junta de Andalucia P06-RNM-189

    In-situ evidence for dextral active motion at the Arabia-India plate boundary

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    International audienceThe Arabia-India plate boundary--also called theOwen fracture zone--is perhaps the least-known boundary among large tectonic plates1-6. Although it was identified early on as an example of a transform fault converting the divergent motion along the Carlsberg Ridge to convergent motion in the Himalayas7, its structure and rate of motion remains poorly constrained. Here we present the first direct evidence for active dextral strike-slip motion along this fault, based on seafloor multibeam mapping of the Arabia-India-Somalia triple junction in the northwest Indian Ocean. There is evidence for 12km of apparent strike-slip motion along the mapped segment of the Owen fracture zone, which is terminated to the south by a 50-km-wide pull-apart basin bounded by active faults. By evaluating these new constraints within the context of geodetic models of global plate motions, we determine a robust angular velocity for the Arabian plate relative to the Indian plate that predicts 2-4mmyr−1 dextral motion along the Owen fracture zone. This transformfault was probably initiated around 8 million years ago in response to a regional reorganization of plate velocities and directions8-11, which induced a change in configuration of the triple junction. Infrequent earthquakes of magnitude 7 and greater may occur along the Arabia-India plate boundary, unless deformation is in the formof aseismic creep

    Tectonic and climatic controls on rift escarpments: Erosion and flexural rebound of the Dhofar passive margin (Gulf of Aden, Oman)

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    International audienceWe investigate the respective roles of climatic parameters and the flexural rigidity of the lithosphere in the erosion history and behavior of two adjacent rift escarpments along the northern coast of the Gulf of Aden, in Oman. At this 25 Myr old passive margin, we define a type 1 scarp, which is high, sharp-crested and has retreated 25-30 km inland from its master fault, and a type 2 scarp, which exhibits a more rounded profile, lower relief, and still coincides with its mapped normal fault trace. Since about 15 Ma, the margin has been seasonally affected by monsoon precipitation but with contrasting effects at the type 1 and type 2 escarpments depending on the position of the Intertropical Convergence Zone in the geologic past: during peak monsoon conditions, both scarps experienced heavy rainfall and runoff, whereas during monsoon-starved conditions (such as today), the type 2 scarp experienced a foggy, moist climate while the type 1 scarp remained much drier. In order to assess the relative effects of climate and flexural parameters on the present-day morphology of the Dhofar margin, we present onedimensional numerical models of erosion and flexure along two profiles representative of the type 1 and type 2 scarps. Unlike most surface process models previously published, where present-day topography is the only criterion by which to evaluate the quality of model outputs, model behavior here is additionally constrained by independent estimates of denudation provided by geological cross sections, well-defined fault traces, and other stratigraphic markers. The best fitting models indicate that the type 1 escarpment formed under relatively arid climatic conditions and was affected by significant erosion, recession and flexural uplift due to a low (7 km) effective elastic thickness. In contrast, the morphology of the type 2 fault scarp was smoothed by a more humid climate, but a high effective elastic thickness ( 15 km) prevented it from uplifting or receding. In addition, we show that the sedimentary load acting at the foot of the escarpments exerts significant influence on their morphological evolution, though this parameter is often neglected in other scarp evolution models

    Crustal structure of the Peruvian continental margin from wide-angle seismic studies

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    Active seismic investigations along the Pacific margin off Peru were carried out using ocean bottom hydrophones and seismometers. The structure and the P-wave velocities of the obliquely subducting oceanic Nazca Plate and overriding South American Plate from 8°S to 15°S were determined by modelling the wide-angle seismic data combined with the analysis of reflection seismic data. Three detailed cross-sections of the subduction zone of the Peruvian margin and one strike-line across the Lima Basin are presented here. The oceanic crust of the Nazca Plate, with a thin pelagic sediment cover, ranging from 0–200 m, has an average thickness of 6.4 km. At 8°S it thins to 4 km in the area of Trujillo Trough, a graben-like structure. Across the margin, the plate boundary can be traced to 25 km depth. As inferred from the velocity models, a frontal prism exists adjacent to the trench axis and is associated with the steep lower slope. Terrigeneous sediments are proposed to be transported downslope due to gravitational forces and comprise the frontal prism, characterized by low seismic P-wave velocities. The lower slope material accretes against a backstop structure, which is defined by higher seismic P-wave velocities, 3.5–6.0 km s−1. The large variations in surface slope along one transect may reflect basal removal of upper plate material, thus steepening the slope surface. Subduction processes along the Peruvian margin are dominated by tectonic erosion indicated by the large margin taper, the shape and bending of the subducting slab, laterally varying slope angles and the material properties of the overriding continental plate. The erosional mechanisms, frontal and basal erosion, result in the steepening of the slope and consequent slope failure
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