107 research outputs found

    Evolving hash functions by means of genetic programming

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    Proceedings of the 8th annual conference on Genetic and evolutionary computation. Seattle, Washington, USA, July 08-12, 2006The design of hash functions by means of evolutionary computation is a relatively new and unexplored problem. In this work, we use Genetic Programming (GP) to evolve robust and fast hash functions. We use a fitness function based on a non-linearity measure, producing evolved hashes with a good degree of Avalanche Effect. Efficiency is assured by using only very fast operators (both in hardware and software) and by limiting the number of nodes. Using this approach, we have created a new hash function, which we call gp-hash, that is able to outperform a set of five human-generated, widely-used hash functions.This article has been financed by the Spanish founded research MCyT project OP:LINK, Ref:TIN2005-08818-C04-02.Publicad

    Finding state-of-the-art non-cryptographic hashes with genetic programming

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    Proceding of: 9th International Conference, Reykjavik, Iceland, September 9-13, 2006.The design of non-cryptographic hash functions by means of evolutionary computation is a relatively new and unexplored problem. In this paper, we use the Genetic Programming paradigm to evolve collision free and fast hash functions. For achieving robustness against collision we use a fitness function based on a non-linearity concept, producing evolved hashes with a good degree of Avalanche Effect. The other main issue, efficiency, is assured by using only very fast operators (both in hardware and software) and by limiting the number of nodes. Using this approach, we have created a new hash function, which we call gp-hash, that is able to outperform a set of five human-generated, widely-used hash functions.This article has been financed by the Spanish founded research MCyT project OP:LINK, Ref:TIN2005-08818-C04-02

    Field experimental study of traffic-induced turbulence on highways

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    This paper is focused on traffic-induced turbulence (TIT) analysis from a field campaign performed in 2011, using ultrasonic anemometers deployed in the M-12 Highways, Madrid (Spain). The study attempts to improve knowledge about the influence of traffic-related parameters on turbulence. Linear relationships between vehicle speed and turbulent kinetic energy (TKE) values are found with coefficients of determination (R2) of 0.75 and 0.55 for the lorry and van respectively. The vehicle-induced fluctuations in the wind components (u', v' and w') showed the highest values for the longitudinal component (v) because of the wake-passing effect. In the analysis of wake produced by moving vehicles it is indicated how the turbulence dissipates in relation to a distance d and height h. The TKE values were found to be higher at the measuring points closer to the surface during the wake analysis.This work was supported by the OASIS Research Project that was co financed by CDTI (Spanish Science and Innovation Ministry) and developed with the Spanish companies: Iridium, OHL Concesiones, Abertis, Sice, Indra, Dragados, OHL, Geocisa, GMV, Asfaltos Augusta, Hidrofersa, Eipsa, PyG, CPS, AEC and Torre de Comares Arquitectos s.l and 16 research centres

    Self-adaptive MOEA feature selection for classification of bankruptcy prediction data

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    Article ID 314728Bankruptcy prediction is a vast area of finance and accounting whose importance lies in the relevance for creditors and investors in evaluating the likelihood of getting into bankrupt. As companies become complex, they develop sophisticated schemes to hide their real situation. In turn, making an estimation of the credit risks associated with counterparts or predicting bankruptcy becomes harder. Evolutionary algorithms have shown to be an excellent tool to deal with complex problems in finances and economics where a large number of irrelevant features are involved.This paper provides a methodology for feature selection in classification of bankruptcy data sets using an evolutionary multiobjective approach that simultaneously minimise the number of features and maximise the classifier quality measure (e.g., accuracy).The proposed methodology makes use of self-adaptation by applying the feature selection algorithm while simultaneously optimising the parameters of the classifier used. The methodology was applied to four different sets of data. The obtained results showed the utility of using the self-adaptation of the classifier.This work was partially supported by the Portuguese Foundation for Science and Technology under Grant PEst-C/CTM/LA0025/2011 (Strategic Project-LA 25-2011-2012) and by the Spanish Ministerio de Ciencia e Innovacion, under the project "Gestion de movilidad efficiente y sostenible, MOVES" with Grant Reference TIN2011-28336

    Sporangia and Spores in the Fern Genera Spicantopsis and Struthiopteris (Blechnaceae, Polypodiopsida)

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    Struthiopteris (Blechnaceae) has recently been classified on the basis of molecular and morphological evidence, and some of its species are now included in the sister genus Spicantopsis. However, the lack of studies on several important morphological features impedes a sound assessment of their congruence with this new systematic arrangement, as well as of their range of variation and taxonomic value in this group of ferns. Here we present a study on the spores and sporangia using both light and scanning electron microscopy in Struthiopteris and Spicantopsis, using samples of all their species, and almost all their varieties. We provide full morphological descriptions of the spores and sporangia of all these taxa. We point out that the perispore structure and ornamentation and the number and the thickness of stomium cells in the sporangium clearly distinguish both generaThe Universidad Complutense de Madrid partially supported this research through the funding of a project PR26/16-20295, and a field trip to Iceland (International Mobility Program 2016

    Sensory function in cluster headache: an observational study comparing the symptomatic and asymptomatic sides

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    Background: Based on inconsistent sensory alterations demonstrated in cluster headache (CH), the aim of this study was to determine whether patients with CH develop sensory changes in the symptomatic side compared to the asymptomatic side. Methods: Quantitative sensory testing (QST), including pressure pain threshold (PPT), tactile detection threshold (TDT), prick detection threshold (PDT), and two-point detection threshold (2PDT), was evaluated in 16 patients (seven women; age 41.9±6.8 years) with CH. Test sites included the rst, second, and third divisions of the trigeminal nerve, cervical spine, and thenar eminence in the symptomatic and asymptomatic sides. Results: The symptomatic side, compared to the asymptomatic side, presented signi cantly decreased PPT in the rst (P=0.011; 423.81±174.05 kPa vs 480.13±214.99 kPa) and second (P=0.023; 288.88±140.80 kPa vs 326.38±137.33 kPa) divisions of the trigeminal nerve, significantly increased TDT in the first (P=0.002; 2.44±0.40 vs 1.74±0.24) and second (P=0.016; 1.92±0.34 vs 1.67±0.09) divisions, and increased 2PDT in the rst division (P=0.004; 18.13±4.70 mm vs 15.0±4.92 mm) and neck (P=0.007; 45.31±20.65 mm vs 38.44±16.10 mm). Conclusion: These results support the prior evidence suggesting a specific pattern of alteration of sensory function with alterations in the symptomatic side compared to the asymp- tomatic side

    Immediate Effects of Upper Cervical Translatoric Mobilization on Cervical Mobility and Pressure Pain Threshold in Patients With Cervicogenic Headache: A Randomized Controlled Trial

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    Objective The purpose of this study was to evaluate the immediate effects of upper cervical translatoric spinal mobilization (UC-TSM) on cervical mobility and pressure pain threshold in subjects with cervicogenic headache (CEH). Methods Eighty-two volunteers (41.54 ± 15.29 years, 20 male and 62 female) with CEH participated in the study and were randomly divided into the control and treatment groups. The treatment group received UC-TSM and the control group remained in the same position for the same time as the UC-TSM group, but received no treatment. Cervical mobility (active cervical mobility and flexion-rotation test), pressure pain thresholds over upper trapezius muscles, C2-3 zygapophyseal joints and suboccipital muscles, and current headache intensity (visual analog scale) were measured before and immediately after the intervention by 2 blinded investigators. Results After the intervention, UC-TSM group exhibited significant increases in total cervical mobility (P =.002, d = 0.16) and the flexion–rotation test (P .05). Nevertheless, there was a significantly lower intensity of headache in the UC-TSM group (P =.039, d = 0.57). Conclusions Upper cervical translatoric spinal mobilization intervention increased upper, and exhibited a tendency to improve general, cervical range of motion and induce immediate headache relief in subjects with CEH

    Ultrasound measurement of the effects of high, medium and low hip long-axis distraction mobilization forces on the joint space width and its correlation with the joint strain

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    Background: No study has evaluated the mechanical effect of different magnitudes of long axis-distraction mobilization (LADM) force on hip joint space width (JSW) or the association between the separation of joint surfaces and the strain on hip capsular ligaments. Objective: To compare the joint separation when applying three different magnitudes of LADM forces (low, medium and high) and to analyse the correlation between joint separation, strain on the inferior ilio-femoral ligament and magnitude of applied force. Design: Repeated measures controlled laboratory cadaveric study. Methods: Three magnitudes of force were applied to 11 cadaveric hip joints (mean age 73 years). Ultrasound images were used to measure joint separation, and strain gauges recorded inferior ilio-femoral ligament strain during each condition. Results: The magnitude of joint separation was significantly different between low (0.23 ± 0.19 mm), medium (0.72 ± 0.22 mm) and high (2.62 ± 0.43 mm) forces (p 0.723; p < 0.001). Conclusion: Hip joint separation and ligament strain during LADM are associated with the magnitude of the applied force

    Influence of 12-week concurrent training on exosome cargo and its relationship with cardiometabolic health parameters in men with obesity

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    [EN] Exosome release varies depending on the physiological state of the cell, so they could play a fundamental role in obesity, the biggest pandemic in today's societies. The beneficial effects that physical activity has both on weight and cardiovascular parameters may be mediated by exosomes released in response to exercise. Thus, we aimed (I) to study the influence of a 12-week CT intervention on exosome cargo modifications in men with obesity and (II) to determine whether changes in exosomes after the intervention were related to changes in cardiometabolic health parameters in our cohorts. An experimental, controlled design was performed in twelve (nine with valid data) adult male obese patients (mean values: 41.6 years old, 97.6 kg and 32.4 kg/m2) who were randomly divided into a control group (n = 4) and a training group (n = 5), which completed 36 sessions of CT (concurrent training) for 12 weeks. Before and after the training period, cardiometabolic health parameters were evaluated and blood samples to measure exosomes and proteins were drawn. No changes were observed in the levels of any exosomal markers and proteins; however, associations of changes between CD81 and both fat mass and weight, Flot-1 and VO2max, HSP70 and both CRP and left ventricle diastolic diameter or CD14 and leptin were found (all p ≀ 0.05). Although the current CT was not able to clearly modify the exosome cargo, a certain medium to large clinical effect was manifested considering the nature of this study. Moreover, the associations found between the promoted changes in cardiometabolic parameters and exosome-carried proteins could indicate a relationship to be considered for future treatments in patients with obesity.SICurrent research activities of D.J.-P. are supported by a grant from the Spanish Ministry of Science and Innovation—MINECO (RYC-2014-16938) and the EXERNET Research Network on Exercise and Health in Special Populations (DEP2005-00046/ACTI). Technology Fund—FEDER funds (R&D&I Operating Program) was used by and for the benefit of companies (Technology Fund) INNTERCONECTA (BRISA Contract-University of CĂĄdiz). The results of the study are presented clearly, honestly and without fabrication, falsification or inappropriate data manipulation.Biomedical Research Networking Center on Frailty and Healthy Aging (CIBERFES) and FEDER funds from the European Union (CB16/10/00477)

    Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects

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    10 p.Aging has been related with a decline in the ability to handle protein folding, which leads to endoplasmic reticulum stress and alterations in unfolded protein response (UPR). Importantly, physical activity could activate the UPR and attenuate or prevent age-induced endoplasmic reticulum (ER) dysfunction. The current study evaluated the effects of a resistance exercise on UPR and mitochondrial functions in peripheral blood mononuclear cells (PBMCs) from elderly subjects. Thirty healthy women and men (age, 72.8, sx− = 2.2 years) were randomized to a training group, which performed an 8-week resistance training programme, or a control group, which followed their daily routines. The phosphorylation of PERK and IRE1, as well as ATF4, and XBP1 protein expression, significantly increased following the training, while expression of BiP, AFT6 and CHOP remain without changes. Additionally, the intervention also induced an increase in PGC-1α and Mfn1 protein levels, while no changes were found in Drp1 expression. Finally, the resistance protocol was not able to activate PINK1/Parkin and Bnip3/Nix pathways. The results obtained seem to indicate that 8-week resistance exercise activates the UPR, stimulates mitochondrial biogenesis, maintains mitochondrial dynamics and prevents mitophagy activation by unfolded proteins in PBMCs from elderly subjects.S
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