Iniciación a la apiterapia.

ÍNDICE Prólogo.Stangaciu, Stefan ¿Qué se conoce como productos de la colmena y cómo se controla su calidad? Vit Olivier, Patricia ¿Es posible la apiterapia sin la apicultura?Vit Olivier, Patricia ¿Es la apicultura una actividad femenina o masculina?Schwartzenberg, Juan Carlos ¿Cuáles plantas visitan las abejas en Chiguará?Morales M., Antonio ¿De dónde provienen los principios activos de los productos de la colmena?Meccia C., Gina ¿Podemos obtener vitaminas de los productos de la colmena?García, Maria Ysabel y Zago, Karina ¿Por qué se estudia la actividad antibacteriana de las mieles?Aguilera, Greana; Gil, Florimar; González, Ana Carolina; Nieves Blanco, Beatriz; Rojas, Yenny y Vit Olivier, Patricia ¿Por qué tienen actividad antioxidante los productos de la colmena?Rodríguez M., Antonio Jesús Técnicas de herbario para plantas visitadas por abejas.Carmona Arzola, Juan y Rodríguez, María ¿Cómo pueden llegar los plaguicidas a la colmena?Luna, José Rafael ¿Puede ocurrir contaminación por metales pesados en la colmena?Di Bernardo, María L. ¿Por qué se presentan los productos de la colmena en preparados farmacéuticos?Isla, Marylenlid ¿Es posible encontrar residuos antibióticos en la miel de abejas y sus preparados?León L., Andrés; Colón U., Sarín; Aranguren, Nelson y Vit Olivier, Patricia ¿Es útil y oportuno un proyecto de apiterapia?González, Isbelia Regulaciones para los productos de la colmena, considerados como productos naturales.Calderón, Laura Notas sobre bioética para apiterapeutas.Vit Olivier, Patricia Índice de palabras claves. Índice de [email protected]@[email protected]@[email protected]@[email protected]@[email protected]@[email protected], [email protected]@apitherapy.com, [email protected][email protected]@[email protected] monográfico20-07-200

Adenosine deaminase enhances the immunogenicity of human dendritic cells from healthy and HIV-infected individuals

ADA is an enzyme implicated in purine metabolism, and is critical to ensure normal immune function. Its congenital deficit leads to severe combined immunodeficiency (SCID). ADA binding to adenosine receptors on dendritic cell surface enables T-cell costimulation through CD26 crosslinking, which enhances T-cell activation and proliferation. Despite a large body of work on the actions of the ecto-enzyme ADA on T-cell activation, questions arise on whether ADA can also modulate dendritic cell maturation. To this end we investigated the effects of ADA on human monocyte derived dendritic cell biology. Our results show that both the enzymatic and non-enzymatic activities of ADA are implicated in the enhancement of CD80, CD83, CD86, CD40 and CCR7 expression on immature dendritic cells from healthy and HIV-infected individuals. These ADA-mediated increases in CD83 and costimulatory molecule expression is concomitant to an enhanced IL-12, IL-6, TNF-α, CXCL8(IL-8), CCL3(MIP1-α), CCL4(MIP-1β) and CCL5(RANTES) cytokine/chemokine secretion both in healthy and HIV-infected individuals and to an altered apoptotic death in cells from HIV-infected individuals. Consistently, ADA-mediated actions on iDCs are able to enhance allogeneic CD4 and CD8-T-cell proliferation, globally yielding increased iDC immunogenicity. Taken together, these findings suggest that ADA would promote enhanced and correctly polarized T-cell responses in strategies targeting asymptomatic HIV-infected individuals

3er. Coloquio: Fortalecimiento de los Colectivos de Docencia

Las memorias del 3er. Coloquio de Fortalecimiento de Colectivos de Docencia deben ser entendidas como un esfuerzo colectivo de la comunidad de académicos de la División de Ciencias y Artes para el Diseño, en medio de la pandemia COVID-19, con el fin de: • Analizar y proponer acciones concretas que promuevan el mejoramiento de la calidad docente en la División. • Proponer acciones que permitan continuar fortaleciendo los cursos con modalidad a distancia (remotos). • Ante un escenario que probablemente demandará en el mediano plazo, transitar del modelo remoto a un modelo híbrido, proponer acciones a considerar para la transición de los cursos. • Planear y preparar cursos de nivelación de conocimientos, para cuando se transite a la impartición de la docencia de manera mixta o presencial, dirigidos a los alumnos que no hayan tenido oportunidad de desarrollar actividades relevantes para su formación, como prácticas de talleres y laboratorios, visitas, o alguna otra actividad relevante

Delayed colorectal cancer care during covid-19 pandemic (decor-19). Global perspective from an international survey

Background The widespread nature of coronavirus disease 2019 (COVID-19) has been unprecedented. We sought to analyze its global impact with a survey on colorectal cancer (CRC) care during the pandemic. Methods The impact of COVID-19 on preoperative assessment, elective surgery, and postoperative management of CRC patients was explored by a 35-item survey, which was distributed worldwide to members of surgical societies with an interest in CRC care. Respondents were divided into two comparator groups: 1) ‘delay’ group: CRC care affected by the pandemic; 2) ‘no delay’ group: unaltered CRC practice. Results A total of 1,051 respondents from 84 countries completed the survey. No substantial differences in demographics were found between the ‘delay’ (745, 70.9%) and ‘no delay’ (306, 29.1%) groups. Suspension of multidisciplinary team meetings, staff members quarantined or relocated to COVID-19 units, units fully dedicated to COVID-19 care, personal protective equipment not readily available were factors significantly associated to delays in endoscopy, radiology, surgery, histopathology and prolonged chemoradiation therapy-to-surgery intervals. In the ‘delay’ group, 48.9% of respondents reported a change in the initial surgical plan and 26.3% reported a shift from elective to urgent operations. Recovery of CRC care was associated with the status of the outbreak. Practicing in COVID-free units, no change in operative slots and staff members not relocated to COVID-19 units were statistically associated with unaltered CRC care in the ‘no delay’ group, while the geographical distribution was not. Conclusions Global changes in diagnostic and therapeutic CRC practices were evident. Changes were associated with differences in health-care delivery systems, hospital’s preparedness, resources availability, and local COVID-19 prevalence rather than geographical factors. Strategic planning is required to optimize CRC care