Partners in Water Quality Monitoring at Mammoth Cave National Park, Kentucky

Water resources are essential to landscape development and maintenance of the extraordinary ecosystem at Mammoth Cave National Park, Kentucky. The National Park Service has implemented many policies and management practices in an effort to maintain and improve the water quality in the park. As part of their resources management, the Park evaluates current hydrologic conditions, as well as, anticipates and responds to emerging issues. With regards to that goal, Mammoth Cave National Park Service partnered with Tennessee State University, the Mammoth Cave International Center for Science and Learning, and the U.S. Geological Survey on a series of water-related projects from 2007-2013. The objective of this paper is to highlight some of the findings and lessons learned from the past 6 years. Many of the results presented in this paper have been presented at other conferences or published in other reports. Collaborative projects included storm-water runoff from parking lots and roads, evaluating storm-water filters, and transport of chemicals in the caves. These projects purposefully engaged students to provide professional experience and educational outreach opportunities. Over 50 student presentations related to these monitoring activities have been made at regional and national conferences in the past 6 years, resulting in numerous awards and publications. Major funding or in-kind services were provided by the partnering agencies and institutions. Additional funding for supplies and student support was provided by the National Science Foundation (Opportunity for Enhancing Diversity in Geoscience, 2007-8; Undergraduate Research and Mentoring, 2009-13), and, the Department of Energy (Massey Chair – NNSA, 2007-13). The following summaries are excerpts from previously published student papers (West et al., 2010; Diehl et al., 2012, Embry, et al., 2012, West et al., 2012)

Preliminary Terrestrial Palynological Re-investigation of the Type Coon Creek Lagerstatte, Tennessee, USA

The type locality for the Campanian Coon Creek Formation, located in McNairy County, Tennessee, is a well-known lagerstatte, with exceptionally preserved marine invertebrate and vertebrate remains in shallow shelf sediments. At the time of deposit ion, the type locality was located in an embayment proximal t o t he eastern margin of the Appalachia province that experienced alternately cool- and warm-water conditions, likely due to currents from both the Western Interior Seaway and Tethys. While marine in their entirety, the sediments contain significant quantities of terrestrial palynomorphs, especially near the top of the section and thus provide a snapshot of adjacent upper Cretaceous terrestrial ecosystems which are not otherwise preserved in this region. A recently completed biostratigraphic study of rangefinder widely-spaced samples through the section suggested that the increase in terrestrial input up-section may be the result of increased fluvial input, as total marine microfossil abundances remain largely unchanged. The biostratigraphic study suggested that more detailed examination of the terrestrial palynomorphs preserved in the section was warranted. In July 2022, the team of co-authors collected 27 fresh samples from the type locality. In this study we present the preliminary results of new biostratigraphic and paleoecological investigations of terrestrial palynomorphs recovered from the site.https://scholarworks.moreheadstate.edu/celebration_posters_2024/1047/thumbnail.jp

Vancomycin and Home Health Care

Microbiologic diagnosis before hospital discharge and physician education may limit inappropriate vancomycin use in homecare patients

Upper extremity impairments in women with or without lymphedema following breast cancer treatment

Breast-cancer-related lymphedema affects ∼25% of breast cancer (BC) survivors and may impact use of the upper limb during activity. The purpose of this study is to compare upper extremity (UE) impairment and activity between women with and without lymphedema after BC treatment. 144 women post BC treatment completed demographic, symptom, and Disability of Arm-Shoulder-Hand (DASH) questionnaires. Objective measures included Purdue pegboard, finger-tapper, Semmes-Weinstein monofilaments, vibration perception threshold, strength, range of motion (ROM), and volume. Women with lymphedema had more lymph nodes removed (p < .001), more UE symptoms (p < .001), higher BMI (p = .041), and higher DASH scores (greater limitation) (p < .001). For all participants there was less strength (elbow flexion, wrist flexion, grip), less shoulder ROM, and decreased sensation at the medial upper arm (p < .05) in the affected UE. These differences were greater in women with lymphedema, particularly in shoulder abduction ROM (p < .05). Women with lymphedema had bilaterally less elbow flexion strength and shoulder ROM (p < .05). Past diagnosis of lymphedema, grip strength, shoulder abduction ROM, and number of comorbidities contributed to the variance in DASH scores (R 2 of 0.463, p < .001). UE impairments are found in women following treatment for BC. Women with lymphedema have greater UE impairment and limitation in activities than women without. Many of these impairments are amenable to prevention measures or treatment, so early detection by health care providers is essential

Vertical Heterophoria and Postural Control in Nonspecific Chronic Low Back Pain

The purpose of this study was to test postural control during quiet standing in nonspecific chronic low back pain (LBP) subjects with vertical heterophoria (VH) before and after cancellation of VH; also to compare with healthy subjects with, and without VH. Fourteen subjects with LBP took part in this study. The postural performance was measured through the center of pressure displacements with a force platform while the subjects fixated on a target placed at either 40 or 200 cm, before and after VH cancellation with an appropriate prism. Their postural performance was compared to that of 14 healthy subjects with VH and 12 without VH (i.e. vertical orthophoria) studied previously in similar conditions. For LBP subjects, cancellation of VH with a prism improved postural performance. With respect to control subjects (with or without VH), the variance of speed of the center of pressure was higher, suggesting more energy was needed to stabilize their posture in quiet upright stance. Similarly to controls, LBP subjects showed higher postural sway when they were looking at a target at a far distance than at a close distance. The most important finding is that LBP subjects with VH can improve their performance after prism-cancellation of their VH. We suggest that VH reflects mild conflict between sensory and motor inputs involved in postural control i.e. a non optimal integration of the various signals. This could affect the performance of postural control and perhaps lead to pain. Nonspecific chronic back pain may results from such prolonged conflict

A CI-Independent Form of Replicative Inhibition: Turn Off of Early Replication of Bacteriophage Lambda

Several earlier studies have described an unusual exclusion phenotype exhibited by cells with plasmids carrying a portion of the replication region of phage lambda. Cells exhibiting this inhibition phenotype (IP) prevent the plating of homo-immune and hybrid hetero-immune lambdoid phages. We have attempted to define aspects of IP, and show that it is directed to repλ phages. IP was observed in cells with plasmids containing a λ DNA fragment including oop, encoding a short OOP micro RNA, and part of the lambda origin of replication, oriλ, defined by iteron sequences ITN1-4 and an adjacent high AT-rich sequence. Transcription of the intact oop sequence from its promoter, pO is required for IP, as are iterons ITN3–4, but not the high AT-rich portion of oriλ. The results suggest that IP silencing is directed to theta mode replication initiation from an infecting repλ genome, or an induced repλ prophage. Phage mutations suppressing IP, i.e., Sip, map within, or adjacent to cro or in O, or both. Our results for plasmid based IP suggest the hypothesis that there is a natural mechanism for silencing early theta-mode replication initiation, i.e. the buildup of λ genomes with oop+ oriλ+ sequence

Inside the Buying Firm:Exploring Responses to Paradoxical Tensions in Sustainable Supply Chain Management

An instrumental perspective still dominates research on sustainable supply chain management (SSCM). As an alternative, this study presents a paradox perspective and argues that sustainability and other business aims are not always compatible, particularly in an emerging market context. Often, paradoxical tensions originate in conflicts between the socioeconomic environment of emerging market suppliers and their Western customers' demands for both cost competitiveness and sustainability. We argue that Western buying firms can play a key role in moderating such tensions, as experienced by emerging market suppliers. Specifically, we explore how purchasing and sustainability managers within buying firms make sense of and respond to paradoxical tensions in SSCM. We conduct an in-depth case study of a Western multinational company that sources substantially from Chinese suppliers. While we found strong evidence for a persisting instrumental perspective in the sensemaking and practices of purchasing and sustainability managers, we also observed an alternative response, primarily by sustainability managers that we labeled as "contextualizing." Contextualizing can alleviate the tensions otherwise present in SSCM by making sustainability standards more workable in an emerging market context, and it can help individual managers to move toward paradoxical sensemaking. We outline the value of paradoxical sensemaking in bringing about changes toward "true sustainability" in SSCM