Solar photo-Fenton at mild conditions to treat a mixture of six emerging pollutants

The applicability of photo-Fenton to degrade a mixture of emerging pollutants (EPs) namely amoxycillin, acetaminophen, acetemiprid, caffeine, clofibric acid and carbamazepine has been studied at different scenarios. At high concentrations, acidic photo-Fenton was able to achieve a fast removal of the EPs. Although, complete mineralization was not reached, the toxicity of the solution was decreased according to the respiration of activated sludge and luminescence of Vibrio fischeri assays, although according to this last assay a transitory enhancement of the toxicity was found, attributable to the formation of toxic byproducts such as phenols, chlorophenols and chlorinated pyrydines. Experiments carried out with 5 mg/l of each EP showed that at neutral media the process was two orders of magnitude less efficient than at acidic pH, although it was still able to remove the EPs. The aqueous matrix has a remarkable effect on the process as the presence of humic acids increased the reaction rate and inorganic salts played an inhibitory role. Finally, experiments performed with 10 lg/l of each EP showed that under those experimental conditions nearly complete removal of the EPs was reached with neutral photo-Fenton after 120 min of irradiation; in this case, humic substances played a disfavorable role.We want to thank the financial support of Spanish Ministerio de Ciencia e Innovacion (CTQ 2009-13459-0O5-03) and (CTQ 2009-3459-C05-01).Bernabeu García, A.; Palacios Guillem, S.; Vicente Candela, R.; Vercher Pérez, RF.; Malato Rodríguez, S.; Arques Sanz, A.; Amat Payá, AM. (2012). Solar photo-Fenton at mild conditions to treat a mixture of six emerging pollutants. Chemical Engineering Journal. 198:65-72. https://doi.org/10.1016/j.cej.2012.05.056S657219

Model-Based Evaluation: A New Way to Support Usability Evaluation of Multimodal Interactive Applications

International audienceMultimodal interfaces are becoming more common, even in the field of safety critical interactive software, mainly due to the naturalness of the interaction that increases the bandwidth between the user and the system they are interacting with. However, the specificities of multimodal interactive systems make it difficult to gather information from the use of modalities and to extract from this information recommendations for improving the multimodal user interfaces. This chapter aims at presenting how abstract information described in models can be fruitfully exploited to improve the quality of evaluations of multimodal interfaces. The approach presented in this chapter combines model-based verification (based on simulation scenario extraction generated from models) and empirical methods for usability evaluation. Our aim is to try to bring together two separated (and often opposite) issues, such as usability and reliability, into the development of safety critical systems. This approach is illustrated via a Space Ground System of a satellite control room, whose multimodal interaction technique is fully described by the means of formal models

Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial

Background Although endovascular aneurysm repair (EVAR) has a lower 30-day operative mortality than open repair, the long-term results of EVAR are uncertain. We instigated EVAR trial 1 to compare these two treatments in terms of mortality, durability, health-related quality of life (HRQL), and costs for patients with large abdominal aortic aneurysm (AAA). Methods We did a randomised controlled trial of 1082 patients aged 60 years or older who had aneurysms of at least 5.5 cm in diameter and who had been referred to one of 34 hospitals proficient in the EVAR technique. We assigned patients who were anatomically suitable for EVAR and fit for an open repair to EVAR (n=543) or open repair (n=539). Our primary endpoint was all-cause mortality, with secondary endpoints of aneurysm-related mortality, HRQL, postoperative complications, and hospital costs. Analyses were by intention to treat. Findings 94% (1017 of 1082) of patients complied with their allocated treatment and 209 died by the end of follow-up on Dec 31, 2004 (53 of aneurysm-related causes). 4 years after randomisation, all-cause mortality was similar in the two groups (about 28%; hazard ratio 0.90, 95% CI 0.69-1.18, p=0.46), although there was a persistent reduction in aneurysm-related deaths in the EVAR group (4% vs 7%; 0.55, 0.31-0.96, p=0.04). The proportion of patients with postoperative complications within 4 years of randomisation was 41% in the EVAR group and 9% in the open repair group (4.9, 3.5-6.8, p<0.0001). After 12 months there was negligible difference in HRQL between the two groups. The mean hospital costs per patient up to 4 years were UK 13257 pound for the EVAR group versus 9946 pound for the open repair group (mean difference 13311, S E 690). Interpretation Compared with open repair, EVAR offers no advantage with respect to all-cause mortality and HRQL, is more expensive, and leads to a greater number of complications and reinterventions. However, it does result in a 3% better aneurysm-related survival. The continuing need for interventions mandates ongoing surveillance and longer follow-up of EVAR for detailed cost-effectiveness assessment