1,680 research outputs found
Wavelet reconstruction of E and B modes for CMB polarisation and cosmic shear analyses
We present new methods for mapping the curl-free (E-mode) and divergence-free (B-mode) components of spin 2 signals using spin directional wavelets. Our methods are equally applicable to measurements of the polarisation of the cosmic microwave background (CMB) and the shear of galaxy shapes due to weak gravitational lensing. We derive pseudo and pure wavelet estimators, where E-B mixing arising due to incomplete sky coverage is suppressed in wavelet space using scale- and orientation-dependent masking and weighting schemes. In the case of the pure estimator, ambiguous modes (which have vanishing curl and divergence
simultaneously on the incomplete sky) are also cancelled. On simulations, we demonstrate the improvement (i.e., reduction in leakage) provided by our wavelet space estimators over standard harmonic space approaches. Our new methods can be directly interfaced in a coherent
and computationally-efficient manner with component separation or feature extraction techniques that also exploit wavelets
Diagnostic and Monitoring CERN Accelerator Controls Infrastructure : The DIAMON Project First Deployment in Operation
The CERN accelerator controls infrastructure spans over several machines and several thousands of devices are used to collect and transmit piece of control data. Each of these remote devices might fail and therefore prevent correct operation. A complete diagnostic and monitoring infrastructure has been developed in order to provide Operation crews with complete and easy to use graphical interface presenting the state of the controls system. Simple agents running in each surveyed item periodically report monitoring information to a central server. Graphical JAVA clients in the operation centers subscribe to this monitoring data and display a view of the current state of the machines. Mouse actions from these clients allows for diagnostic commands to be sent to the agent to get additional details or to repair a faulty situation. This presentation will describe the overall architecture of DIAMON, present the different agents running in the controls system and a few views of the graphical clients. The outcome of the first months in operation of the DIAMON tools will also be presented. Finally, the future plans will be exposed
A connection between stress and development in the multicelular prokaryote Streptomyces coelicolor
Morphological changes leading to aerial mycelium formation and sporulation in the mycelial bacterium Streptomyces coelicolor rely on establishing distinct patterns of gene expression in separate regions of the colony. sH was identified previously as one of three paralogous sigma factors associated with stress responses in S. coelicolor. Here, we show that sigH and the upstream gene prsH (encoding a putative antisigma factor of sH) form an operon transcribed from two developmentally regulated promoters, sigHp1 and sigHp2. While sigHp1 activity is confined to the early phase of growth, transcription of sigHp2 is dramatically induced at the time of aerial hyphae formation. Localization of sigHp2 activity using a transcriptional fusion to the green fluorescent protein reporter gene (sigHp2–egfp) showed that sigHp2 transcription is spatially restricted to sporulating aerial hyphae in wild-type S. coelicolor. However, analysis of mutants unable to form aerial hyphae (bld mutants) showed that sigHp2 transcription and sH protein levels are dramatically upregulated in a bldD mutant, and that the sigHp2–egfp fusion was expressed ectopically in the substrate mycelium in the bldD background. Finally, a protein possessing sigHp2 promoter-binding activity was purified to homogeneity from crude mycelial extracts of S. coelicolor and shown to be BldD. The BldD binding site in the sigHp2 promoter was defined by DNase I footprinting. These data show that expression of sH is subject to temporal and spatial regulation during colony development, that this tissue-specific regulation is mediated directly by the developmental transcription factor BldD and suggest that stress and developmental programmes may be intimately connected in Streptomyces morphogenesis
A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase
Simocyclinones are bifunctional antibiotics that inhibit bacterial DNA gyrase by preventing DNA binding to the enzyme. We report the crystal structure of the complex formed between the N-terminal domain of the Escherichia coli gyrase A subunit and simocyclinone D8, revealing two binding pockets that separately accommodate the aminocoumarin and polyketide moieties of the antibiotic. These are close to, but distinct from, the quinolone-binding site, consistent with our observations that several mutations in this region confer resistance to both agents. Biochemical studies show that the individual moieties of simocyclinone D8 are comparatively weak inhibitors of gyrase relative to the parent compound, but their combination generates a more potent inhibitor. Our results should facilitate the design of drug molecules that target these unexploited binding pockets
Large scale cosmic-ray anisotropy with KASCADE
The results of an analysis of the large scale anisotropy of cosmic rays in
the PeV range are presented. The Rayleigh formalism is applied to the right
ascension distribution of extensive air showers measured by the KASCADE
experiment.The data set contains about 10^8 extensive air showers in the energy
range from 0.7 to 6 PeV. No hints for anisotropy are visible in the right
ascension distributions in this energy range. This accounts for all showers as
well as for subsets containing showers induced by predominantly light
respectively heavy primary particles. Upper flux limits for Rayleigh amplitudes
are determined to be between 10^-3 at 0.7 PeV and 10^-2 at 6 PeV primary
energy.Comment: accepted by The Astrophysical Journa
Primary Proton Spectrum of Cosmic Rays measured with Single Hadrons
The flux of cosmic-ray induced single hadrons near sea level has been
measured with the large hadron calorimeter of the KASCADE experiment. The
measurement corroborates former results obtained with detectors of smaller size
if the enlarged veto of the 304 m^2 calorimeter surface is encounted for. The
program CORSIKA/QGSJET is used to compute the cosmic-ray flux above the
atmosphere. Between E_0=300 GeV and 1 PeV the primary proton spectrum can be
described with a power law parametrized as
dJ/dE_0=(0.15+-0.03)*E_0^{-2.78+-0.03} m^-2 s^-1 sr^-1 TeV^-1. In the TeV
region the proton flux compares well with the results from recent measurements
of direct experiments.Comment: 13 pages, accepted by Astrophysical Journa
Fracton pairing mechanism for "strange" superconductors: Self-assembling organic polymers and copper-oxide compounds
Self-assembling organic polymers and copper-oxide compounds are two classes
of "strange" superconductors, whose challenging behavior does not comply with
the traditional picture of Bardeen, Cooper, and Schrieffer (BCS)
superconductivity in regular crystals. In this paper, we propose a theoretical
model that accounts for the strange superconducting properties of either class
of the materials. These properties are considered as interconnected
manifestations of the same phenomenon: We argue that superconductivity occurs
in the both cases because the charge carriers (i.e., electrons or holes)
exchange {\it fracton excitations}, quantum oscillations of fractal lattices
that mimic the complex microscopic organization of the strange superconductors.
For the copper oxides, the superconducting transition temperature as
predicted by the fracton mechanism is of the order of K. We suggest
that the marginal ingredient of the high-temperature superconducting phase is
provided by fracton coupled holes that condensate in the conducting
copper-oxygen planes owing to the intrinsic field-effect-transistor
configuration of the cuprate compounds. For the gate-induced superconducting
phase in the electron-doped polymers, we simultaneously find a rather modest
transition temperature of K owing to the limitations imposed by
the electron tunneling processes on a fractal geometry. We speculate that
hole-type superconductivity observes larger onset temperatures when compared to
its electron-type counterpart. This promises an intriguing possibility of the
high-temperature superconducting states in hole-doped complex materials. A
specific prediction of the present study is universality of ac conduction for
.Comment: 12 pages (including separate abstract page), no figure
Tunable variation of optical properties of polymer capped gold nanoparticles
Optical properties of polymer capped gold nanoparticles of various sizes
(diameter 3-6 nm) have been studied. We present a new scheme to extract size
dependent variation of total dielectric function of gold nanoparticles from
measured UV-Vis absorption data. The new scheme can also be used, in principle,
for other related systems as well. We show how quantum effect, surface atomic
co - ordination and polymer - nanoparticle interface morphology leads to a
systematic variation in inter band part of the dielectric function of gold
nanoparticles, obtained from the analysis using our new scheme. Careful
analysis enables identification of the possible changes to the electronic band
structure in such nanoparticles.Comment: 13 pages,7 figures, 1 tabl
Proporción diaria de alimento del diablillo antártico (pleuragramma antarcticum boulenger, 1902) en el este del mar de weddell
[EN] The daily ration of Pleuragramma antarcticum in the Eastern Weddell Sea was investigated from midwater and bottom trawl samples collected in the Antarctic in the summer of 1998. Using a gastric evacuation model that takes into account Weddell Sea temperature below zero and information on the prey type daily ration estimates were: 1.133% BW for immature fish of 10-16 cm and 0.484% BW for mature fish of 17-24 cm. The low daily ration intake was influenced by the low temperatures that limited the rate of gastric evacuation. This model seems more realistic than results from the classic Elliot & Persson and Eggers models that are also used in this paper, since their assumptions on feeding regularity are more rigid and they do not consider data of energy density of the prey[ES] La ración diaria de alimento de Pleuragramma antarcticum en el mar de Weddell es investigada en muestras de arrastres de fondo y pelágicas recogidas durante diferentes horas del día en el verano antártico de 1998. Utilizando un modelo de evacuación gástrica que tiene en cuenta la temperatura bajo del Mar de Weddell e información sobre el tipo de presa, las estimaciones de consumo diario fueron: 1.133% BW para peces inmaduros entre 10 -16 cm y 0.484% BW para peces maduros entre 17-24 cm. La baja ración diaria ingerida estuvo influida por las bajas temperaturas que limitan la tasa de evacuación gástrica. Este modelo parece más realista que los resultados de los modelos clásicos de Elliot & Persson and Eggers también empleados, ya que sus asunciones sobre su periodicidad de alimentación son más rígidas y no consideran datos de densidad energética de las presasThis work was conducted under the SCAR EASIZ programme, and was supported by the Alfred Wegener Institute and the Spanish Antarctic ProgrammePeer reviewe
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