4,162 research outputs found

    Investigation of electrical properties for cantilever-based piezoelectric energy harvester

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    In the present era, the renewable sources of energy, e.g., piezoelectric materials are in great demand. They play a vital role in the field of micro-electromechanical systems, e.g., sensors and actuators. The cantilever-based piezoelectric energy harvesters are very popular because of their high performance and utilization. In this research-work, an energy harvester model based on a cantilever beam with bimorph PZT-5A, having a substrate layer of structural steel, was presented. The proposed energy scavenging system, designed in COMSOL Multiphysics, was applied to analyze the electrical output as a function of excitation frequencies, load resistances and accelerations. Analytical modeling was employed to measure the output voltage and power under pre-defined conditions of acceleration and load resistance. Experimentation was also performed to determine the relationship between independent and output parameters. Energy harvester is capable of producing the maximum power of 1.16 mW at a resonant frequency of 71 Hz under 1g acceleration, having load resistance of 12 k Omega. It was observed that acceleration and output power are directly proportional to each other. Moreover, the investigation conveys that the experimental results are in good agreement with the numerical results. The maximum error obtained between the experimental and numerical investigation was found to equal 4.3%

    Production, purification and partial characterization of lipase from Trichoderma Viride

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    A new strain of lipolytic Trichoderma viride was isolated from the soil on a selective mediumthat contained olive oil as the only source of carbon and energy. The isolated strain was cultivated for lipase production in shake flasks at 30Ā±1oC and the fermentation pattern was studied. The maximum extracellular lipase activity of 7.3 U/mL and the maximum intracellularactivity of 320 U/g mycelium were noted after 48 h. Although maximum fungal biomass was present at 13.6 g/L at 60 h but highest specific growth rate was observed between 6 and 18 h.The extracellular lipase present in the broth was purified 134-folds with an overall yield of 46% through purification procedure of ammonium sulphate precipitation, ion exchange and gelpermeation chromatography. The Km value of the purified enzyme for triolein hydrolysis was found to be 1.229 m.mole/L

    Baseline study in environmental risk assessment: Escalating need for computer models to be whole-system approach

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    This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Accepted author version posted online: 12 Dec 2016Despite landfills having the potential to pollute the environment both during their operation and long after they have ceased to receive waste, they remain a dominant waste management option, particularly in the UK. In order to combat the environmental pollution caused by landfills, risk analysis is increasingly being employed through computer models. However, for a risk analysis process to be successful, its foundation has to be well established through a baseline study. This paper aims to identify knowledge gaps in software packages regarding environmental risk assessments in general, and especially those that have been developed specifically for landfills and landfill leachate. The research establishes that there is no holistic computer model for the baseline study of landfills, which risk assessors can use to conduct risk analyses specifically for landfill leachate. This paper also describes a number of factors and features that should be added to the baseline study system in order to render it more integratedā€”thereby enhancing quantitative risk analysis, and subsequently environmental risk management.The authors acknowledge the financial support of Dundee City Council in this project. We are additionally grateful for the discussion and help received from Mr Peter Goldie of the Environment & Consumer Protection Department, Dundee City Council. The support from Dr I. M. Spence (Consultant Environmental Geologist, Scotland), and colleagues at the University of Abertay Dundee, including Dr Kehinde O. K. Oduyemi and Mr Phillip Jenkins is also highly 39 appreciated. It must be noted that concepts and ideas presented in this article by the authors do not necessarily represent views that of their respective employer organization

    Thermal Model of Rotary Friction Welding for Similar and Dissimilar Metals

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    Friction welding is one of the foremost welding processes for similar and dissimilar metals. Previously, the process has been modeled utilizing the rudimentary techniques of constant friction and slip-stick friction. The motivation behind this article is to present a new characteristic for temperature profile estimation in modeling of the rotary friction welding process. For the first time, a unified model has been exhibited, with an implementation of the phase transformation of similar and dissimilar materials. The model was generated on COMSOL MultiphysicsĀ® and thermal and structural modules were used to plot the temperature curve. The curve for the welding of dissimilar metals using the model was generated, compared and analyzed with that of practical curves already acquired through experimentation available in the literature, and then the effect of varying the parameters on the welding of similar metals was also studied

    Improvement over time in outcomes for patients undergoing endoscopic therapy for Barrett's oesophagus-related neoplasia: 6-year experience from the first 500 patients treated in the UK patient registry

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    Background: Barrettā€™s oesophagus (BE) is a pre-malignant condition leading to oesophageal adenocarcinoma (OAC). Treatment of neoplasia at an early stage is desirable. Combined endoscopic mucosal resection (EMR) followed by Radiofrequency ablation (RFA) are alternatives to surgery for patients with Barrettā€™s related neoplasia. Methods: We examine prospective data from United Kingdom (UK) Registry of patients undergoing RFA/EMR for BE related neoplasia from 2008 to 2013. Before RFA, visible lesions were removed by EMR. Thereafter patients had RFA 3 monthly until all BE was ablated or cancer developed (endpoints). End of treatment biopsies were recommended at around 12 months from first RFA treatment or when endpoints reached. Outcomes for clearance of dysplasia (CR-D) & BE (CR-IM) at end of treatment were assessed over two time periods, between 2008-2010 and 2011-2013. Durability of successful treatment and progression to OAC were also evaluated. Results: 508 patients have completed treatment. CR-D and CR-IM have improved significantly between former and later time periods, from 77% and 56% to 92% and 83% respectively (p<0.0001). EMR for visible lesions prior to RFA increased from 48% to 60% (p=0.013). Rescue EMR after RFA decreased from 13% to 2% (p<0.0001). Progression to OAC at 12 months is not significantly different (3.6% versus 2.1%, p=0.51). Conclusion: Clinical outcomes for BE neoplasia have improved significantly over the past 6 years with improved lesion recognition, and aggressive resection of visible lesions before RFA. Despite advances in technique, the rate of cancer progression remains 2-4% at 1 year in these high risk patients

    Prognostic Information for Known Genetic Carriers of RB1 Pathogenic Variants (Germline and Mosaic)

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    OBJECTIVE: To compare the number of tumors per eye for mosaic carriers of RB1 pathogenic variants with full germline variants and the conversion from unilateral to bilateral disease. DESIGN: Retrospective cohort study comparing patients with retinoblastoma and different genetic subtypes (HP: high penetrant, LP: low penetrant & mosaicism). SUBJECTS: Data were analysed between 1992 and 2018 at the Retinoblastoma Unit, Royal London Hospital, London UK. All familial patients had a parent with a known pathogenic variant even if the parent did not manifest the disease. MAIN OUTCOME MEASURES: Number of tumors per eye in children who developed retinoblastoma in that eye. Other outcomes included total number of tumors per patient, age at diagnosis, laterality at presentation and later, sex and stage according to International Intraocular Retinoblastoma Classification RESULTS: 111 patients were included: 64 full germline, familial patients (53 HP and 11 LP) & 47 were mosaic patients. 12 (23%) of HP patients were unilateral and 8 of 12 (67%) developed tumors in their previously unaffected eye. 34 (72%) of mosaic patients were unilateral and only 2 (6%) developed tumors in their unaffected eye. Age at diagnosis was higher in mosaic patients (median 22 months) than HP patients (median 7) (p<0.00002). Number of tumors per eye was fewer in patients with mosaic alleles (median 1.0 range 1-6) compared to patients with HP alleles (median 3.0 range 1-8) (p<0.0003). All three children (4 eyes) with mosaicism and more than 2 tumors per eye had high levels of mosaicism. CONCLUSIONS: Children with mosaic alleles have fewer tumors per eye compared to those with known high penetrant pathogenic variants and are more likely to remain unilateral. The level of mosaicism has an impact on laterality and number of tumors

    Preliminary nitrite, nitrate and colour analysis of Malaysian edible birdā€™s nest

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    AbstractThe high nitrite content in edible birdā€™s nests is a major concern to the local swiftlet industry. It lowers the price of the edible birdā€™s nests and it brings severe health hazards to consumers and farmers. This research investigated the nitrite and nitrate contents of eight types of local edible birdā€™s nests by using ion chromatography system and evaluating its colour using the CIE system in Lāˆ—aāˆ—bāˆ— parameters. The nitrite content obtained ranged from 5.7Ī¼g/g for the house nests to 843.8Ī¼g/g for the cave nests. The nitrate content for the house and cave nests was 98.2Ī¼g/g and 36,999.4Ī¼g/g, respectively. The cave nests with darker and redder colour had higher nitrite and nitrate contents than the brighter and more yellow house nests. This likely suggests that the nitrite and nitrate contents have correlations with edible birdā€™s nests colour. Correlations studies suggested that the nitrite content had high correlations with colour parameters, Lāˆ—aāˆ—bāˆ— of edible birdā€™s nests at significant level of P<0.10. These findings suggest that edible birdā€™s nestsā€™ colour may be a useful indicator for measuring nitrite and nitrate contaminations

    Towards Comprehensive Computational Representations of Arabic Multiword Expressions

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    A successful computational treatment of multiword expressions (MWEs) in natural languages leads to a robust NLP system which considers the long-standing problem of language ambiguity caused primarily by this complex linguistic phenomenon. The first step in addressing this challenge is building an extensive reliable MWEs language resource LR with comprehensive computational representations across all linguistic levels. This forms the cornerstone in understanding the heterogeneous linguistic behaviour of MWEs in their various manifestations. This paper presents a detailed framework for computational representations of Arabic MWEs (ArMWEs) across all linguistic levels based on the state-of-the-art lexical mark-up framework (LMF) with the necessary modifications to suit the distinctive properties of Modern Standard Arabic (MSA). This work forms part of a larger project that aims to develop a comprehensive computational lexicon of ArMWEs for NLP and language pedagogy LP (JOMAL project)
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