The Effects of a Summer Camp Experience on Factors of Resilience in At-Risk Youth

This pilot study addressed the impact of a summer camp experience on at-risk middle school youth by exploring self-reported growth in skill development and resilience. Campers who attended a five-week summer day camp were compared to a control group who maintained typical activities throughout the summer. Results showed statistically significant differences in the campers’ belief of a good future for themselves (U = 179.40, P = 0.05). Campers reported sustained or positive growth in domains of social skills and positive values from the baseline to a six-month follow up. Three significant themes emerged from individual in-depth interviews including: (a) engagement influences skill competence, (b) the camp environment expands positive choice and availability of positive occupations, and (c) males developed skills and resilience from informal physical activity while no equivalent existed for females. Middle school aged at-risk youth can benefit from occupation-based summer camp programs that promote active engagement in an enriched environment and sustain gains once they return to high-risk environments. This research contributes to a growing understanding of the potential contribution of occupational therapy in the design and delivery of effective summer camp experiences for at-risk youth

Developing the public health function of locum pharmacists under the auspices of the new pharmacy contract

Focal Point - There are reduced opportunities for locum pharmacists to access training and education that meets their needs and enables them to play a full role under the new pharmacy contract - Eighty-six per cent of locums consider themselves to be more health professional than business person, compared to just 48% of pharmacy owners - Forty per cent of locums believe that a lack of access to training is a major barrier to the development of their public health function - While locum pharmacists are arguably more likely to embrace 'professionalising', patient-care-based roles, they are also the group least likely to be able to access the necessary training to fulfill such roles Introduction It has been suggested that locum pharmacists do not want the business-based responsibilities (e.g. staff management, meeting targets, etc) that come with pharmacy management.1 Research also suggests that locums derive great satisfaction from the health-professional aspects of the pharmacists’ role (e.g. patient contact, the provision of advice, etc).1 However, upon the introduction of the new pharmacy contract (April 2005), concerns were expressed that it was becoming increasingly difficult for locum pharmacists to access training and education that would meet their needs and enable them to play a full role under the new framework.2,3 Method After piloting, in August 2006 a self-completion postal questionnaire was sent to a random sample of practising community pharmacists, stratified for country and sex, within Great Britain (n = 1998), with a follow-up to non-responders 4 weeks later. Data were analysed using SPSS (v12.0). A final response rate of 51% (n = 1023/1998) was achieved. Respondents were asked ‘indicate how you view yourself as a pharmacist’ – in terms of their relative focus on the health-professional and business aspects of their role. Respondents were also asked ‘do you consider a lack of training opportunities to be a barrier to the development of the public health role of community pharmacists?’. Results Locums were significantly more likely than owners or employees to consider each factor a major barrier. Discussion Four in 10 locums consider a lack of training opportunities to constitute a major barrier to the development of their public health function. Pharmacy may not be able to provide the services required of it by the policy agenda if pharmacists are unable to be involved in extended role activities through a lack of training opportunities. Therefore, the paradox that needs to be addressed is that while locum pharmacists are arguably more likely to embrace ‘professionalising’, patient-care-based roles, they are also the group least likely to be able to access training to fulfil such roles. The training needs of this large subset of the pharmacist population need to be assessed and met if the whole community pharmacy workforce is going to maximise its contribution to public health under the new contractual framework. References 1 Shann P, Hassell K. An exploration of the diversity and complexity of the pharmacy locum workforce. London: Royal Pharmaceutical Society of Great Britain; 2004. 2 Almond M. Locums – key players in workforce – cast adrift as contract launched. Pharm J 2005;274:420. 3 Bishop DH. A lack of appreciation of what really happens. Pharm J 2005;274:451

Community pharmacy in a commissioning-led NHS:can pharmacy compete effectively?

Introduction – The commissioning of services has been a core responsibility of English Primary Care Trusts (PCTs) since 2002. Primary care organisations (PCOs) in Scotland, Wales and Northern Ireland have also increased their commissioning activities but with, arguably, less fervour than their English counterparts. The commissioning function of English PCTs has been reinforced by the introduction of new contractual frameworks across primary care – for medical services, dentistry and pharmacy. The new pharmaceutical services contract for England and Wales introduced an “enhanced” category of services, the provision of which is dependent on the commissioning decisions of local PCTs. As the NHS, most pertinently in England, continues its transformation from a provider to a commissioner of healthcare, the ability of pharmacy to compete effectively for funding is likely to become increasingly important. Method - After piloting, in August 2006 a self-completion postal questionnaire was sent to a random sample of practising community pharmacists, stratified for country and sex, within Great Britain (n=1998), with a follow-up to non-responders 4 weeks later. Data were analysed using SPSS (v12.0). A final response rate of 51% (n=1023/1998) was achieved. Within the section of the questionnaire relating to service provision, respondents were asked “do you believe that pharmacy will be able to compete effectively with other healthcare providers for access to additional funding to develop services that address a public health need identified by your local Primary Care Organisation (PCO), e.g. PCT/LHB etc.?”. Answers were recorded on a three-point scale; pharmacy “will”, “may”, or “will not” be able to compete effectively for funding. Results - The attitudes of pharmacists showed variation depending on the type of pharmacy they worked in (supermarket, multiple (outlets (n)=200), large chain (200>n>20), small chain (20=n>5), or independent (n=5)) (?2 test with p=0.001). Over a third of survey pharmacists working in small chains and independents (37% (n=21/57) and 33% (n=113/341) respectively) believed that pharmacy would not be able to compete effectively for funding compared to 23% (n=15/65) for supermarket pharmacists, 22% (n=21/97) for pharmacists employed by large chains and just 18% (n=62/353) for pharmacists employed most regularly in multiples. Furthermore, attitudes also varied between the countries of residence of respondents (?2 test with p<0.05). 27% (n=242/893) of pharmacists resident in England and Wales believed that pharmacy would not be able to compete compared to 16% (n=18/116) of pharmacists resident in Scotland. Conclusions – It would appear that community pharmacists believe that the larger pharmacy chains and supermarkets will occupy an advantageous position in terms of attracting finance to develop services. This could have notable implications for service provision across the sector. If corporate pharmacy chains were to monopolise commissioning monies then the proportion of funding available to independents will be diminished; arguably further hastening their demise, as well as stifling the professional development of pharmacists employed within the independent sector. These findings, when combined with the variation observed between UK pharmacists operating under different contractual frameworks, may be a reflection of the divergent policy in the different administrations with developments in England, including the new pharmacy contract, reflecting a market-based approach with Scotland taking a near opposite stance with service integration and a commitment to new public health. However, it should be acknowledged that the questionnaire did not allow for detection of ambiguities in, or misunderstandings of, the survey question and this should be considered as a limitation of the research

In vivo optogenetic manipulations of endogenous proteins reveal spatiotemporal roles of microtubule and kinesin in dendrite patterning.

During animal development, the spatiotemporal properties of molecular events largely determine the biological outcomes. Conventional gene analysis methods lack the spatiotemporal resolution for precise dissection of developmental mechanisms. Although optogenetic tools exist for manipulating designer proteins in cultured cells, few have been successfully applied to endogenous proteins in live animals. Here, we report OptoTrap, a light-inducible clustering system for manipulating endogenous proteins of diverse sizes, subcellular locations, and functions in Drosophila. This system turns on fast, is reversible in minutes or hours, and contains variants optimized for neurons and epithelial cells. By using OptoTrap to disrupt microtubules and inhibit kinesin-1 in neurons, we show that microtubules support the growth of highly dynamic dendrites and that kinesin-1 is required for patterning of low- and high-order dendritic branches in differential spatiotemporal domains. OptoTrap allows for precise manipulation of endogenous proteins in a spatiotemporal manner and thus holds promise for studying developmental mechanisms in a wide range of cell types and developmental stages

Acute Cardiometabolic Responses to Medicine Ball Interval Training in Children

International Journal of Exercise Science 11(4): 886-899, 2018. Medicine ball interval training (MBIT) has been found to be an effective exercise modality in fitness programs, yet the acute physiological responses to this type of this exercise in youth are unknown. The purpose of this study was to examine the acute cardiometabolic responses to MBIT in children. Fourteen children (mean age 10.1 ± 1.3 yr) were tested for peak oxygen uptake (VO2peak) on a treadmill and subsequently (\u3e 48 hours later) performed a progressive 10 min MBIT protocol of 5 exercises (EX): standing marches (EX1), alternating lunges (EX2), squat swings (EX3), chest passes (EX4) and double arm slams (EX5). A 2.3 kg medicine ball was used for all trials and each exercise was performed twice for 30 sec with a 30 sec rest interval between sets and exercises. Participants exercised while connected to a metabolic system and heart rate (HR) monitor. During the MBIT protocol, mean HR significantly (p\u3c0.05, η2= 0.89) increased from 121.5 ± 12.3 bpm during EX1 to 178.3 ± 9.4 bpm during EX5 and mean VO2 significantly (p\u3c0.05, η2= 0.88) increased from 15.5 ± 2.9 ml ×kg-1×min-1during EX1 to 34.9 ± 5.1 ml ×kg-1×min-1during EX5. Mean HR and VO2values during MBIT ranged from 61.1% to 89.6% of HRpeak and from 28.2% to 63.5% of VO2peak. These descriptive data indicate that MBIT can pose a moderate to vigorous cardiometabolic stimulus in children

Use of Heart Rate Index to Predict Oxygen Uptake – A Validation Study

International Journal of Exercise Science 13(7): 1705-1717, 2020. An equation that uses heart rate index (HRI) defined as HR/HRrest to predict oxygen uptake (VO2) in METs (e.g., METs = 6 × HRI ‒ 5) has been developed retrospectively from aggregate data of 60 published studies. However, the prediction error of this model as used by an individual has not been established. Therefore, the purpose of this study was to examine the predictive validity of the HRI equation by comparing submaximal and maximal VO2 predicted by the equation (VO2-Pred) with that measured by indirect calorimetry (VO2-Meas). Sixty healthy adults (age 20.5 ± 2.4 yr., body mass 69.4 ± 13.4 kg, height 1.7 ± 0.1 m) underwent a VO2max test and an experimental trial consisting of a 15-min resting measurement and three successive 10-min treadmill exercise bouts performed at 40%, 60% and 80% of VO2max. VO2 and HR were recorded during both the submaximal and maximal exercises and used to obtain VO2-Pred and VO2-Meas for each intensity and for VO2max. Validation was carried out by paired t-test, regression analysis, and Bland-Altman plots. A modest but significant (p \u3c 0.05) correlation was observed between VO2-Meas and VO2-Pred at 40% (r = 0.58), 60% (r = 0.53), and 80% of VO2max (r = 0.56) and at VO2max (r = 0.50). No differences between VO2-Pred and VO2-Meas were found at 40% (5.53 ± 1.21 vs. 5.28 ± 0.98 METs, respectively) of VO2max, but VO2-Pred was higher (p \u3c 0.05) than VO2-Meas at 60% (8.42 ± 1.77 vs. 7.96 ± 1.39 METs, respectively) and 80% (10.79 ± 2.13 vs. 10.29 ± 1.81 METs, respectively) of VO2max. In contrast, VO2-Pred was lower (p \u3c 0.05) than VO2-Meas at VO2max (12.32 ± 2.30 vs. 13.38 ± 2.24 METs, respectively). Standard errors of the estimate were 0.81, 1.20, 1.54, and 1.97 METs at 40%, 60%, 80% of VO2max and at VO2max, respectively. These results suggest that further investigation aimed to establish the accuracy of using HRI to predict VO2 is warranted

Cardiometabolic responses of body-weight exercises with and without vibration

This investigation examined the interactive effect of body-weight (BW) exercises and vibration on cardiometabolic responses. Fourteen subjects performed a BW exercise protocol with (BW+V) and without (BW‒V) vibration in a randomized order. The BW exercise protocol consisted of three circuits of eight calisthenics-based exercises including prisoner squat, push-up, isometric squat, reverse dip, lunge, flutter kicks, isometric lunge, and T push-up. Vibratory frequency and amplitude were set at 40 Hz and 4 mm, respectively. Oxygen uptake (VO2), heart rate (HR), expired ventilation (VE), and blood lactate [La] were determined during the protocol and 30-minute recovery. The mean VO2 reached 48% and 50% of VO2max and the mean HR reached 80% and 83% of HRmax in BW‒V and BW+V, respectively. During the protocol, while the mean VE was greater (p=.031) in BW+V than BW‒V, no differences were seen for VO2 and HR between the two conditions. During recovery, while mean VO2 was greater (p=.002) in BW+V than BW-V, no differences were seen for VE and HR between the two conditions. [La] values were significantly elevated but remained similar between the two conditions. Exercise-specific VO2 was higher during the prisoner squat (p=.003) and isometric squat (p=.042) in BW+V than BW‒V, while no differences in VO2 were observed for all other exercises. Performing three circuits of eight BW exercises in a rapid-and-intense manner produced a sufficient increase in cardiometabolic responses. Metabolic potentiation associated with combining vibration with BW exercises seemed to be influenced by how the exercises were carried out on a vibration plate

A novel approach for quantitative imaging of the seated anatomy of the buttocks using ultrasound and MRI

DATA AVAILABILITY STATEMENT : The original contributions presented in the study are included in the article/Supplementary Material. Further inquiries can be directed to the corresponding author.BACKGROUND : Pressure injuries are commonly noted in individuals who use wheelchairs for mobility and sit for prolonged periods. Understanding soft tissue composition is an essential part of treating and preventing pressure injuries. This study proposes novel approaches for imaging the soft tissue of the buttocks in unloaded and loaded conditions using ultrasound (US) and magnetic resonance imaging (MRI). METHODS : The soft tissue of the buttocks was measured in able-bodied participants (n = 26, 50% female) and one male with a spinal cord injury using an innovative chair that allowed seated US acquisition of the buttocks and a newly developed MRI compatible loader. The US test–retest reliability (reproducibility) of buttocks soft tissue was assessed, and US was validated with MRI. Soft tissue was measured between the peak of the ischial tuberosity (IT) and proximal femur and the skin. MRI was used to quantify the fat fraction of the gluteus maximus muscle, with the goal of determining the influence of intramuscular fat on loaded soft tissue responses and was used to assess tissue thickness during buttocks loading. RESULTS : US reproducibility was excellent, ICC = 0.934–0.981, with no statistical differences between scan days. Coefficients of variation (CVs) between visits ranged from 2.5% to 7.4% for loaded and unloaded tissue. US and MRI measures of tissue thickness were significantly correlated (r = 0.68–0.91, p ≤ 0.001). US underestimated the unloaded tissue thicknesses, with a mean bias of 0.39–0.56 cm. When the buttocks were loaded, US- and MRI-measured total tissue thickness was reduced by up to 64.2% ± 9.1% (p 0.05). CONCLUSION : We have developed and validated a novel US methodology using MRI as a comparison measure to investigate soft tissue anatomy and deformation during sitting and loading. The ability to obtain such data in the loaded condition is unique and fills an unmet need in understanding loading and pressure injury formation.The Michigan State University Alliance for African Partnership, the Michigan State University Department of Radiology and NSF—grant # 2044254 (TB) and University of Pretoria UCDP Teaching Replacement Grant.http://www.frontiersin.org/Physicsam2024AnatomySDG-03:Good heatlh and well-bein

A novel approach for quantitative imaging of the seated anatomy of the buttocks using ultrasound and MRI

Background: Pressure injuries are commonly noted in individuals who use wheelchairs for mobility and sit for prolonged periods. Understanding soft tissue composition is an essential part of treating and preventing pressure injuries. This study proposes novel approaches for imaging the soft tissue of the buttocks in unloaded and loaded conditions using ultrasound (US) and magnetic resonance imaging (MRI).Methods: The soft tissue of the buttocks was measured in able-bodied participants (n = 26, 50% female) and one male with a spinal cord injury using an innovative chair that allowed seated US acquisition of the buttocks and a newly developed MRI compatible loader. The US test–retest reliability (reproducibility) of buttocks soft tissue was assessed, and US was validated with MRI. Soft tissue was measured between the peak of the ischial tuberosity (IT) and proximal femur and the skin. MRI was used to quantify the fat fraction of the gluteus maximus muscle, with the goal of determining the influence of intramuscular fat on loaded soft tissue responses and was used to assess tissue thickness during buttocks loading.Results: US reproducibility was excellent, ICC = 0.934–0.981, with no statistical differences between scan days. Coefficients of variation (CVs) between visits ranged from 2.5% to 7.4% for loaded and unloaded tissue. US and MRI measures of tissue thickness were significantly correlated (r = 0.68–0.91, p ≤ 0.001). US underestimated the unloaded tissue thicknesses, with a mean bias of 0.39–0.56 cm. When the buttocks were loaded, US- and MRI-measured total tissue thickness was reduced by up to 64.2% ± 9.1% (p &lt; 0.001). The US- and MRI-unloaded total soft tissue of the IT was correlated with loaded tissue thickness (r = 0.54–0.67, p ≤ 0.027). Intramuscular fat of the gluteus maximus was not correlated to changes in muscle thickness with loading (r = 0.05, p &gt; 0.05).Conclusion: We have developed and validated a novel US methodology using MRI as a comparison measure to investigate soft tissue anatomy and deformation during sitting and loading. The ability to obtain such data in the loaded condition is unique and fills an unmet need in understanding loading and pressure injury formation