2,160 research outputs found

    Scalable simultaneous multi-qubit readout with 99.99% single-shot fidelity

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    We describe single-shot readout of a trapped-ion multi-qubit register using space and time-resolved camera detection. For a single qubit we measure 0.9(3)x10^{-4} readout error in 400us exposure time, limited by the qubit's decay lifetime. For a four-qubit register (a "qunybble") we measure an additional error of only 0.1(1)x10^{-4} per qubit, despite the presence of 4% optical cross-talk between neighbouring qubits. A study of the cross-talk indicates that the method would scale with negligible loss of fidelity to ~10000 qubits at a density <~1 qubit/um^2, with a readout time ~1us/qubit.Comment: 4 pages, 3 figures; simulations added to fig.3, with some further text and figure revisions. Main results unchanged

    Children and young people’s experiences of completing mental health and wellbeing measures for research: learning from two school-based pilot projects

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    BACKGROUND: In recent years there has been growing interest in child and adolescent mental health and wellbeing, alongside increasing emphasis on schools as a crucial site for research and intervention. This has coincided with an increased use of self-report mental health and wellbeing measures in research with this population, including in school-based research projects. We set out to explore the way that children and young people perceive and experience completing mental health and wellbeing measures, with a specific focus on completion in a school context, in order to inform future measure and research design. METHODS: We conducted semi-structured interviews and focus groups with 133 participants aged 8–16 years following their completion of mental health and wellbeing measures as part of school-based research programmes, using thematic analysis to identify patterns of experience. FINDINGS: We identified six themes: Reflecting on emotions during completion; the importance of anonymity; understanding what is going to happen; ease of responding to items; level of demand; and interacting with the measure format. CONCLUSIONS: Our findings offer greater insight into children and young people’s perceptions and experiences in reporting on their mental health and wellbeing. Such understanding can be used to support more ethical and robust data collection procedures in child and adolescent mental health research, both for data quality and ethical purposes. We offer several practical recommendations for researchers, including facilitating this in a school context

    Children and young people’s experiences of completing mental health and wellbeing measures for research: learning from two school‑based pilot projects

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    Background: In recent years there has been growing interest in child and adolescent mental health and wellbeing, alongside increasing emphasis on schools as a crucial site for research and intervention. This has coincided with an increased use of self-report mental health and wellbeing measures in research with this population, including in school-based research projects. We set out to explore the way that children and young people perceive and experience completing mental health and wellbeing measures, with a specific focus on completion in a school context, in order to inform future measure and research design. Methods: We conducted semi-structured interviews and focus groups with 133 participants aged 8–16 years following their completion of mental health and wellbeing measures as part of school-based research programmes, using thematic analysis to identify patterns of experience. Findings: We identified six themes: Reflecting on emotions during completion; the importance of anonymity; understanding what is going to happen; ease of responding to items; level of demand; and interacting with the measure format. Conclusions: Our findings offer greater insight into children and young people’s perceptions and experiences in reporting on their mental health and wellbeing. Such understanding can be used to support more ethical and robust data collection procedures in child and adolescent mental health research, both for data quality and ethical purposes. We offer several practical recommendations for researchers, including facilitating this in a school context

    Reputation in European Trade Mark Law: A Re-examination

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    Under the harmonised European trade mark regime marks with a reputation enjoy expanded protection. This article casts doubt on whether this ‘reputational trigger’ can be justified. It then explores some difficult operational questions about the way the reputation threshold works in cases where the mark enjoys fame only in niche markets or in a limited geographical area, the aim being to illustrate further why reputation is an unsatisfactory trigger for a different type of trade mark protection. Finally, it looks at some of the evidential difficulties involved in adjudicating disputes in which expanded protection is being claimed. It concludes by suggesting that if the evidential problems we identify were tackled the reputation threshold could be abandoned

    Condensation of microturbulence-generated shear flows into global modes

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    In full flux-surface computer studies of tokamak edge turbulence, a spectrum of shear flows is found to control the turbulence level and not just the conventional (0,0)-mode flows. Flux tube domains too small for the large poloidal scale lengths of the continuous spectrum tend to overestimate the flows, and thus underestimate the transport. It is shown analytically and numerically that under certain conditions dominant (0,0)-mode flows independent of the domain size develop, essentially through Bose-Einstein condensation of the shear flows.Comment: 5 pages, 4 figure

    Axisymmetric equilibria of a gravitating plasma with incompressible flows

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    It is found that the ideal magnetohydrodynamic equilibrium of an axisymmetric gravitating magnetically confined plasma with incompressible flows is governed by a second-order elliptic differential equation for the poloidal magnetic flux function containing five flux functions coupled with a Poisson equation for the gravitation potential, and an algebraic relation for the pressure. This set of equations is amenable to analytic solutions. As an application, the magnetic-dipole static axisymmetric equilibria with vanishing poloidal plasma currents derived recently by Krasheninnikov, Catto, and Hazeltine [Phys. Rev. Lett. {\bf 82}, 2689 (1999)] are extended to plasmas with finite poloidal currents, subject to gravitating forces from a massive body (a star or black hole) and inertial forces due to incompressible sheared flows. Explicit solutions are obtained in two regimes: (a) in the low-energy regime β0≈γ0≈δ0≈ϵ0≪1\beta_0\approx \gamma_0\approx \delta_0 \approx\epsilon_0\ll 1, where β0\beta_0, γ0\gamma_0, δ0\delta_0, and ϵ0\epsilon_0 are related to the thermal, poloidal-current, flow and gravitating energies normalized to the poloidal-magnetic-field energy, respectively, and (b) in the high-energy regime β0≈γ0≈δ0≈ϵ0≫1\beta_0\approx \gamma_0\approx \delta_0 \approx\epsilon_0\gg 1. It turns out that in the high-energy regime all four forces, pressure-gradient, toroidal-magnetic-field, inertial, and gravitating contribute equally to the formation of magnetic surfaces very extended and localized about the symmetry plane such that the resulting equilibria resemble the accretion disks in astrophysics.Comment: 12 pages, latex, to be published in Geophys. Astrophys. Fluid Dynamic

    Apraxia and motor dysfunction in corticobasal syndrome

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    Background: Corticobasal syndrome (CBS) is characterized by multifaceted motor system dysfunction and cognitive disturbance; distinctive clinical features include limb apraxia and visuospatial dysfunction. Transcranial magnetic stimulation (TMS) has been used to study motor system dysfunction in CBS, but the relationship of TMS parameters to clinical features has not been studied. The present study explored several hypotheses; firstly, that limb apraxia may be partly due to visuospatial impairment in CBS. Secondly, that motor system dysfunction can be demonstrated in CBS, using threshold-tracking TMS, and is linked to limb apraxia. Finally, that atrophy of the primary motor cortex, studied using voxel-based morphometry analysis (VBM), is associated with motor system dysfunction and limb apraxia in CBS.   Methods: Imitation of meaningful and meaningless hand gestures was graded to assess limb apraxia, while cognitive performance was assessed using the Addenbrooke's Cognitive Examination - Revised (ACE-R), with particular emphasis placed on the visuospatial subtask. Patients underwent TMS, to assess cortical function, and VBM.   Results: In total, 17 patients with CBS (7 male, 10 female; mean age 64.4+/2 6.6 years) were studied and compared to 17 matched control subjects. Of the CBS patients, 23.5% had a relatively inexcitable motor cortex, with evidence of cortical dysfunction in the remaining 76.5% patients. Reduced resting motor threshold, and visuospatial performance, correlated with limb apraxia. Patients with a resting motor threshold <50% performed significantly worse on the visuospatial sub-task of the ACE-R than other CBS patients. Cortical function correlated with atrophy of the primary and pre-motor cortices, and the thalamus, while apraxia correlated with atrophy of the pre-motor and parietal cortices.   Conclusions: Cortical dysfunction appears to underlie the core clinical features of CBS, and is associated with atrophy of the primary motor and pre-motor cortices, as well as the thalamus, while apraxia correlates with pre-motor and parietal atrophy
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