14 research outputs found
Unitarity Triangle from CP invariant quantities
We construct the CKM unitarity triangle from CP invariant quantities, using
the coupling constant of weak decays with flavor change from b to u, and the
particle - antiparticle mixing probability in the B_s and B_d systems. Also
included are new measurements of the coupling V_us in Kaon decays. Of the two
solutions, one agrees perfectly with the triangle constructed from CP violating
processes in the K and B meson systems. The common solution yields a triangle
with an area of J/2 = (1.51 +/- 0.09) x 10^{-5} and a CP violating phase gamma
= 63.1^o +/- 4.0^o.Comment: 8 pages, 3 figure
Role of ABO blood group in SARS-CoV-2 infection in households
An association between certain ABO/Rh blood groups and susceptibility to SARS-CoV-2 infection has been proposed for adults, although this remains controversial. In children and adolescents, the relationship is unclear due to a lack of robust data. Here, we investigated the association of ABO/Rh blood groups and SARS-CoV-2 in a multi-center study comprising 163 households with 281 children and 355 adults and at least one SARS-CoV-2 seropositive individual as determined by three independent assays as a proxy for previous infection. In line with previous findings, we found a higher frequency of blood group A (+ 6%) and a lower frequency of blood group O (−6%) among the SARS-CoV-2 seropositive adults compared to the seronegative ones. This trend was not seen in children. In contrast, SARS-CoV-2 seropositive children had a significantly lower frequency of Rh-positive blood groups. ABO compatibility did not seem to play a role in SARS-CoV-2 transmission within the families. A correction for family clusters was performed and estimated fixed effects of the blood group on the risk of SARS-CoV-2 seropositivity and symptomatic infection were determined. Although we found a different distribution of blood groups in seropositive individuals compared to the reference population, the risk of SARS-CoV-2 seropositivity or symptomatic infection was not increased in children or in adults with blood group A or AB versus O or B. Increasing age was the only parameter positively correlating with the risk of SARS-CoV-2 infection. In conclusion, specific ABO/Rh blood groups and ABO compatibility appear not to predispose for SARS-CoV-2 susceptibility in children
High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection.
The COVID-19 course and immunity differ in children and adults. We analyzed immune response dynamics in 28 families up to 12 months after mild or asymptomatic infection. Unlike adults, the initial response is plasmablast-driven in children. Four months after infection, children show an enhanced specific antibody response and lower but detectable spike 1 protein (S1)-specific B and T cell responses than their parents. While specific antibodies decline, neutralizing antibody activity and breadth increase in both groups. The frequencies of S1-specific B and T cell responses remain stable. However, in children, one year after infection, an increase in the S1-specific IgA class switch and the expression of CD27 on S1-specific B cells and T cell maturation are observed. These results, together with the enhanced neutralizing potential and breadth of the specific antibodies, suggest a progressive maturation of the S1-specific immune response. Hence, the immune response in children persists over 12 months but dynamically changes in quality, with progressive neutralizing, breadth, and memory maturation. This implies a benefit for booster vaccination in children to consolidate memory formation
Search for heavy neutrinos in decays
International audienceThe NA62 experiment recorded a large sample of K+→μ+νμ decays in 2007. A peak search has been performed in the reconstructed missing mass spectrum. In the absence of a signal, limits in the range 2×10−6 to 10−5 have been set on the squared mixing matrix element |Uμ4|2 between muon and heavy neutrino states, for heavy neutrino masses in the range 300–375 MeV/ c2 . The result extends the range of masses for which upper limits have been set on the value of |Uμ4|2 in previous production search experiments
Measurement of the form factors of charged kaon semileptonic decays
International audienceA measurement of the form factors of charged kaon semileptonic decays is presented, based on 4.4 × 10K → πeν (K ) and 2.3 × 10K → πμ±ν (K ) decays collected in 2004 by the NA48/2 experiment. The results are obtained with improved precision as compared to earlier measurements. The combination of measurements in the K and K modes is also presented
Review of Particle Physics, 1998-1999
A comprehensive review of the field of Particle Physics produced by the Particle Data Group (PDG). Includes a compilation/evaluation of data on particle properties, summary tables with best values and limits for particle properties, extensive summari particles, and a long section of reviews, tables, and plots on a wide variety of theoretical and experimental topics of interest to particle and astrophysicists
First observation and study of the decay
The NA48/2 experiment at CERN reports the first observation of the decay based on a sample of 2437 candidates with 15% background contamination collected in 2003-2004. The decay branching ratio in the kinematic region of the squared dilepton mass above ~GeV is measured to be . The extrapolation to the full kinematic space, using a specific model, is found to be , in agreement with chiral perturbation theory predictions
First observation and study of the decay
International audienceThe NA48/2 experiment at CERN reports the first observation of the K → ππμν decay based on a sample of 2437 candidates with 15% background contamination collected in 2003–2004. The decay branching ratio in the kinematic region of the squared dilepton mass above 0.03 GeV/c is measured to be (0.65 ± 0.03) × 10. The extrapolation to the full kinematic space, using a specific model, is found to be (3.45 ± 0.16) × 10, in agreement with chiral perturbation theory predictions