Probing the Inner Regions of Protoplanetary Disks with CO Absorption Line Spectroscopy

Carbon monoxide (CO) is the most commonly used tracer of molecular gas in the inner regions of protoplanetary disks. CO can be used to constrain the excitation and structure of the circumstellar environment. Absorption line spectroscopy provides an accurate assessment of a single line-of-sight through the protoplanetary disk system, giving more straightforward estimates of column densities and temperatures than CO and molecular hydrogen emission line studies. We analyze new observations of ultraviolet CO absorption from the Hubble Space Telescope along the sightlines to six classical T Tauri stars. Gas velocities consistent with the stellar velocities, combined with the moderate-to-high disk inclinations, argue against the absorbing CO gas originating in a fast-moving disk wind. We conclude that the far-ultraviolet observations provide a direct measure of the disk atmosphere or possibly a slow disk wind. The CO absorption lines are reproduced by model spectra with column densities in the range N(^{12}CO) ~ 10^{16} - 10^{18} cm^{-2} and N(^{13}CO) ~ 10^{15} - 10^{17} cm^{-2}, rotational temperatures T_{rot}(CO) ~ 300 - 700 K, and Doppler b-values, b ~ 0.5 - 1.5 km s^{-1}. We use these results to constrain the line-of-sight density of the warm molecular gas (n_{CO} ~ 70 - 4000 cm^{-3}) and put these observations in context with protoplanetary disk models.Comment: 12 pages, 14 figures, ApJ - accepte

The efficacy of different torque profiles for weight compensation of the hand

Orthotic wrist supports will be beneficial for people with muscular weakness to keep their hand in a neutral rest position and prevent potential wrist contractures. Compensating the weight of the hands is complex since the level of support depends on both wrist and forearm orientations. To explore simplified approaches, two different weight compensation strategies (constant and linear) were compared to the theoretical ideal sinusoidal profile and no compensation in eight healthy subjects using a mechanical wrist support system. All three compensation strategies showed a significant reduction of 47-53% surface electromyography activity in the anti-gravity m. extensor carpi radialis. However, for the higher palmar flexion region, a significant increase of 44-61% in the m. flexor carpi radialis was found for all compensation strategies. No significant differences were observed between the various compensation strategies. Two conclusions can be drawn: (1) a simplified torque profile (e.g., constant or linear) for weight compensation can be considered as equally effective as the theoretically ideal sinusoidal profile and (2) even the theoretically ideal profile provides no perfect support as other factors than weight, such as passive joint impedance, most likely influence the required compensation torque for the wrist joint

The CO-H2 conversion factor of diffuse ISM: Bright 12CO emission also traces diffuse gas

We show that the XCO factor, which converts the CO luminosity into the column density of molecular hydrogen has similar values for dense, fully molecular gas and for diffuse, partially molecular gas. We discuss the reasons of this coincidence and the consequences for the understanding of the interstellar medium.Comment: 5 pages, 1 PostScript figure. To be published in the proceedings of the Zermatt 2010 conference: "Conditions and impact of star formation: New results with Herschel and beyond". Uses EAS LaTeX macro

Masculinity as Governance: police, public service and the embodiment of authority, c. 1700-1850

About the book: Public Men offers an introduction to an exciting new field: the history of masculinities in the political domain and will be essential reading for students and specialists alike with interests in gender or political culture. By building upon new work on gender and political culture, these new case studies explore the gendering of the political domain and the masculinities of the men who have historically dominated it. As such, Public Men is a major contribution to our understanding of the history of Britain between the Eighteenth and the Twentieth centuries

1031-35 Value of Ibopamine as Adjunct to Maximal Oral Medication in Patients with Moderately Severe Congestive Heart Failure; a Double-Blind, Placebo-controlled Study

Multiple drug therapy, including ACE inhibitors, diuretics, vasodilators and digoxin is currently used to reduce signs and symptoms of chronic heart failure (CHF). Optimal treatment of these patients (pts) is a major clinical problem, as the prevalence of CHF increases. Ibopamine, a novel oral dopamine agonist with peripheral vasodilating and neurohumoral inhibiting effects, may have additive value in the treatment of pts with moderately severe CHF, already treated with ACE-inhibitors.To evaluate the additive value of ibopamine as adjunctive to maximal CHF treatment we studied 60 pts with NYHA class III-IV CHF, who were assigned to treatment with ibopamine (3 dd 100mg) or placebo in a double-blind, randomized fashion.We examined the effect of ibopamine on peak oxygen consumption (VO2), neurohumoral factors and cardiac arrhythmias during 48 hrs ECG monitoring. Neurohumoral parameters were determined at rest and during exercise and included serum norepinephrine, epinephrine, aldosterone and plasma renin activity. All assessments were made at baseline and after 12 weeks of study treatment.Baseline dataOf the 60 pts, 40 pts (67%) had ischemic heart disease andlor old myocardial infarction, and 20 (33%) non-ischemic heart disease (16 pts (27%) dilated myocardiopathy). Mean age was 63±10 years, left ventricular ejection fraction 0.23±0.08, peak VO2 15.0±2.4 ml/min/kg and 44 of the patients (73%) were male. Background CHF therapy included ACE-inhibitors (100%), diuretics (100%), and digoxin, nitrates, amiodarone when required. At baseline resting serum norepinephrine was 724±78pg/ml, epinephrine 68±17pg/ml, aldosterone 0.50±0.08nmol/l and plasma renin activity 5.7±0.9ng/ml/hr.ResultsThe study was recently completed, the study data are currently analyzed and the results will be presented at the meeting

Characterizing CO Fourth Positive Emission in Young Circumstellar Disks

Carbon Monoxide is a commonly used IR/sub-mm tracer of gas in protoplanetary disks. We present an analysis of ultraviolet CO emission in {HST}-COS spectra for 12 Classical T Tauri stars. Several ro-vibrational bands of the CO A^1\Pi - X^1\Sigma^+ (Fourth Positive) electronic transition system are spectrally resolved from emission of other atoms and H_2. The CO A^1\Pi v'=14 state is populated by absorption of Ly\alpha photons, created at the accretion column on the stellar surface. For targets with strong CO emission, we model the Ly\alpha radiation field as an input for a simple fluorescence model to estimate CO rotational excitation temperatures and column densities. Typical column densities range from N_{CO} = 10^{18} - 10^{19} cm^{-2}. Our measured excitation temperatures are mostly below T_{CO} = 600 K, cooler than typical M-band CO emission. These temperatures and the emission line widths imply that the UV emission originates in a different population of CO than that which is IR-emitting. We also find a significant correlation between CO emission and the disk accretion rate M_{acc} and age. Our analysis shows that ultraviolet CO emission can be a useful diagnostic of CTTS disk gas

Imaging galactic diffuse gas: Bright, turbulent CO surrounding the line of sight to NRAO150

To understand the environment and extended structure of the host galactic gas whose molecular absorption line chemistry, we previously observed along the microscopic line of sight to the blazar/radiocontinuum source NRAO150 (aka B0355+508), we used the IRAM 30m Telescope and Plateau de Bure Interferometer to make two series of images of the host gas: i) 22.5 arcsec resolution single-dish maps of 12CO J=1-0 and 2-1 emission over a 220 arcsec by 220 arcsec field; ii) a hybrid (interferometer+singledish) aperture synthesis mosaic of 12CO J=1-0 emission at 5.8 arcsec resolution over a 90 arcsec-diameter region. CO components that are observed in absorption at a moderate optical depth (0.5) and are undetected in emission at 1 arcmin resolution toward NRAO 150 remain undetected at 6 arcsec resolution. This implies that they are not a previously-hidden large-scale molecular component revealed in absorption, but they do highlight the robustness of the chemistry into regions where the density and column density are too low to produce much rotational excitation, even in CO. Bright CO lines around NRAO150 most probably reflect the variation of a chemical process, i.e. the C+-CO conversion. However, the ultimate cause of the variations of this chemical process in such a limited field of view remains uncertain.Comment: 18 pages, 22 PostScript files giving 14 figures. Accepted for publication in Astronomy & Astrophysics in the letter section. Uses aa LaTeX macro

Imaging galactic diffuse clouds: CO emission, reddening and turbulent flow in the gas around Zeta Oph

Methods: 12CO emission is imaged in position and position-velocity space analyzed statistically, and then compared with maps of total reddening and with models of the C+ - CO transition in H2-bearing diffuse clouds. Results: Around Zeta Oph, 12CO emission appears in two distinct intervals of reddening centered near EBV = 0.4 and 0.65 mag, of which < 0.2 mag is background material. Within either interval, the integrated 12CO intensity varies up to 6-12 K-km/s compared to 1.5 K-km/s toward Zeta Oph. Nearly 80% of the individual profiles have velocity dispersions < 0.6 km/s, which are subsonic at the kinetic temperature derived from H2 toward Zeta Oph, 55 K. Partly as a result, 12CO emission exposes the internal, turbulent, supersonic (1-3 km/s) gas flows with especial clarity in the cores of strong lines. The flows are manifested as resolved velocity gradients in narrow, subsonically-broadened line cores. Conclusions: The scatter between N(CO) and EBV in global, CO absorption line surveys toward bright stars is present in the gas seen around Zeta Oph, reflecting the extreme sensitivity of N(12CO) to ambient conditions. The two-component nature of the optical absorption toward Zeta Oph is coincidental and the star is occulted by a single body of gas with a complex internal structure, not by two distinct clouds. The very bright 12CO lines in diffuse gas arise at N(H2) ~ 10^21/cm^2 in regions of modest density n(H) ~ 200-500/cc and somewhat more complete C+-CO conversion. Given the variety of structure in the foreground gas, it is apparent that only large surveys of absorption sightlines can hope to capture the intrinsic behavior of diffuse gas.Comment: 2009 A&A, in pres

Sex Differences in the Association Between Serum Testosterone and Kidney Function in the General Population

Introduction: Testosterone might prevent kidney function decline, although evidence is limited in men and lacking in women from the general population. We investigated the association between serum testosterone and kidney function in men and women from a large population-based cohort study. Methods: Participants aged ≥45 years with available measurements of serum testosterone, sex hormone-binding globulin (SHBG), creatinine, and cystatine C were included. Assessments of kidney function included baseline assessments of the estimated glomerular filtration rate (eGFR) based on serum creatinine (eGFRcreat) or serum cystatin C (eGFRcys), and the urine albumin-to-creatinine ratio (ACR), and repeated assessments of eGFRcreat. Linear regression and linear mixed models were used to assess the associations of serum free and total testosterone with kidney function, stratified for sex. Results: A total of 4095 men and 5389 women (mean age 65.2 years) were included. In men, higher free testosterone was associated with lower eGFRcreat (beta −0.63, 95% confidence interval [CI]: −1.05; −0.21), higher eGFRcys (beta 0.56, 95% CI: 0.07; 1.05), and lower ACR (beta −0.25, 95% CI: −0.35; −0.16) at baseline. Higher total testosterone was associated with higher baseline and follow-up eGFRcreat, and with lower eGFRcreat when additionally adjusted for SHBG. In women, higher free testosterone was associated with lower baseline eGFRcreat and eGFRcys (beta −1.03, 95% CI: −1.36; −0.71; beta −1.07, 95% CI: −1.44; −0.70; respectively) and lower eGFRcreat over time (beta −0.78, 95% CI: −1.10; −0.46), but not with ACR. Conclusions: eGFRcys might be a better parameter than eGFRcreat for the association of testosterone with kidney function, although further studies investigating this are needed. Furthermore, we identified sex differences in the association between testosterone and kidney function, with a positive association in men and a negative association in women.</p