Kadın öykü yazarlarında aile (1990-2000)

Bu çalışmada kadın yazarlarımızın 1990-2000 yılları arasında yayımlanan öykü kitaplarında aile temasını ele alış biçimleri incelenmiştir. Kadın bakış açısıyla yazılan öykülerde aile meselesinin kadın merkezli ele alındığı görülmüştür. Tezin ana konuları ailenin toplum ile ilişkisi ve aile bireyleri arasındaki ilişkilerdir. Hiçbir edebî metin yazıldığı dönemden ayrı ele alınamaz. Küreselleşme, modernleşme ve sanayileşme sonucunda dünyada toplum yapısının değişmesi ile aile yapısında değişimler yaşanmıştır. Bu değişimlere rağmen Türkiye’de hâkim olan geleneksel aile yapısında köklü değişimler yaşanmamıştır. Ele alınan öykülerdeki ailelerde ataerkil yapının egemen olduğu görülmüştür. Öykülerde aile içinde erkek otoritesinin süregeldiğine ve kadının ikinci plana atıldığına rastlanmıştır. Aile içinde yaşanan sıkıntılardan en fazla kadınların ve çocukların etkilendiği görülmüştür. Kadınların kocalarıyla, çocukların ebeveynleriyle olan ilişkilerinin anlatıldığı öykülerde kadınlar ve çocuklar mutsuzlardır. Değişen zaman ve mekân karşısında aile ve toplumun kadına biçtiği rol modernleşse de geleneksel aile tipinin egemen olduğu öykülerde kadın rolünde hiçbir değişikliğin olmadığı görülmüştür. Ataerkil toplumun belirlediği kadın rolünde kadınlarımız erkekler karşısında söz hakkına sahip değillerdir. Kadın yazarlarımız hakları elinden alınan, erkek otoritesi altında ezilen kadınlarımızın yaşamlarını eleştirel ve çarpıcı bir dille öykülerinde işlemişlerdir. Aile ortamı çocuğun kişiliğinin ve hayata bakış açısının şekillendiği yerdir. Öykülerdeki çocukların aile ortamında mutlu olmadığına rastlanmıştır. Öykülerde genellikle kız çocuklarının ebeveynleri tarafından erkek çocukları karşısında değersizleştirildiği ve hakları ile özgürlüklerinin kısıtlandığı görülmüştür. İncelenen öykülerde kadın yazarlarımızın aile konularını ele alışlarında kadından yana bir tavır takındıkları görülmüştür. Aile teması içinde incelenen meselelerde kadın sorunlarına kadın hassasiyeti ile yaklaşan yazarlar, Türk ailesinde ezilen kadınların sesi olmaya çalışmışlardır. -------------------- In this study, it’s investigated how women authors contextualise “family theme” in their published story books between 1990-2000. It’s seen that family issue is centered on woman in the written stories with woman’s point of view. The main topics of the thesis are the relationship between the family and the society and the relations between the family members. None of the literary texts can be elaborated on separately from the period in which it’s written. As a result of globalization, modernization and industrialization, family structure has had changes with the change in the social structure in the world. Although these changes, the traditional family structure in Turkey has not have drastic changes. It’s seen that the patriarchal structure is dominant in the families which in the stories examined stories. In the stories, it’s found that the male authority in the family is continuing and the woman is taken to the second plan. It’s seen that women and children are affected the most by the problems experienced in the family. Women and children are unhappy in the stories of women's relationship with their husbands and children's relationship with parents. Although the role of woman in family and society has changed in modernization in the face of changing time and place, it’s seen that there is no change in the role of women in the stories of traditional family type. In the woman's role in patriarchal society, our women do not have the right to speak against men. In their stories, our women authors censoriously mention that the lives of the women who have no rights and oppressed under the authority of men. Family is where the child's personality and life perspective are shaped. The children in the stories are not happy in the family environment. In the stories, it’s observed that girls are devalued by their parents comparing boys, and girls’ rights and freedoms are restricted. In the stories that examined, it’s seen that our women authors take a stand for women in handling family issues. The authors approaching women's issues with women's sensitivity in the issues examined within the theme of family have tried to be the voice of the oppressed women in the Turkish family

Hoarding Disorder Trough Three Case, A New Mental Disorder in DSM-5

Compulsive hoarding is a problem characterized with excessive collection and accumulation, failure to discard the excess amount of collected items. Although it is considered to be a symptom of obsessive-compulsive disorder in DSMIV- TR (Diagnostic and statistical manual of mental disorders fourth edition text revision), it is thought that compulsive hoarding and OCD may have different biological, cognitive and behavioral mechanisms and compulsive hoarding may be associated with many other psychological illnesses. For these reasons, in DSM-5 (Diagnostic and statistical manual of mental disorders fifth edition) hoarding disorder diagnosis is located under the classification of obsessive-compulsive and related disorders. In this case report, three cases classified in different diagnostic categories according to DSM-IV-TR will be mentioned and hoarding disorder will be discussed

Influence of hyperopia and amblyopia on choroidal thickness in children

WOS: 000393691000030PubMed: 26541109Purpose: To compare subfoveal choroidal thicknesses (ChTs) of anisometropic hyperopic amblyopic, hyperopic nonamblyopic, and emmetropic control eyes and to investigate the associations between ChT and ambylopia, spherical equivalent (SE), and axial length in the pediatric population. Methods: Forty-six hyperopic nonamblyopic (hyperopic group), 33 anisometropic hyperopic amblyopic (amblyopic group), and 42 emmetropic (emmetropic group) eyes were enrolled in this cross-sectional comparative study. Enhanced depth imaging spectral-domain optical coherence tomography was used for quantitative analysis of subfoveal ChT. ChT was quantified manually as the distance between the hyperreflective line corresponding to the retinal pigment epithelium and the chorioscleral interface at the subfoveal area. Results: the mean age was 10.6 +/- 3.3 years (range 5-17) in the hyperopic group, 10.7 +/- 3.3 years (range 5-17) in the amblyopic group, and 11.2 +/- 3.3 years (range 5-17 years) in the emmetropic group (p = 0.627). the hyperopic and amblyopic groups had significantly thicker choroid compared to the emmetropic group (p1 = 0.005 and p2 = 0.006, respectively). However, there was no significant difference between the hyperopic and amblyopic groups concerning subfoveal ChT (p = 0.857). in addition, covariance analysis showed that although SE was independently associated with subfoveal ChT (p = 0.014), amblyopia had no significant independent effect on subfoveal ChT (p = 0.671). Further, subfoveal ChT had weak correlations with the axial length (r = -0.297, p = 0.001) and SE (r = 0.274, p = 0.002). Conclusions: Hyperopia was associated with subfoveal ChT, whereas amblyopia had no independent significant effect on subfoveal ChT in our study population

Associations between choroidal thickness, axial length and spherical equivalent in a paediatric population

WOS: 000379963700009PubMed: 27151380BackgroundThe aim was to compare the choroidal thickness (ChT) of myopic children's eyes with that of emmetropes to determine whether there are associations between ChT, axial length and spherical equivalent (SE) in a paediatric population. MethodsA total of 117 eyes of 117 children including 53 myopic eyes (myopic group) and 64 emmetropic eyes (emmetropic group) were enrolled in this cross-sectional comparative study. ChT was analysed by using the HD 5 Line Raster scan protocol of spectral domain enhanced depth imaging optical coherence tomography. Subfoveal ChT was measured manually as the distance between the retinal pigment epithelium and the chorioscleral border and three additional measurements were carried out every 750 m temporal (T1, T2 and T3) and nasal (N1, N2 and N3) to the fovea. ResultsThe mean age was 11.7 2.7 years (range five to 17 years) in the myopic group and 10.9 +/- 3.4 years (range 5 to 17 years) in the emmetropic group. There were no significant differences between the groups concerning age and sex (both p > 0.05). the myopic eyes had significantly thinner subfoveal, T1, T2, T3, N1, N2, N3 and average choroid than the emmetropic eyes (all p < 0.05). in addition, correlation analyses among all the study subjects showed that all subfoveal, T1, T2, T3, N1, N2, N3 and average ChT had negative correlations with axial length and positive correlations with the SE. ConclusionThe present study showed that the myopic children's eyes had significantly thinner subfoveal choroid than the emmetropic control eyes. Further, ChT was negatively correlated with axial length and positively correlated with SE in the population that included myopic and emmetropic children

Neutrophil-to-lymphocyte ratio increases in patients with dry eye

Uzun, Feyzahan/0000-0002-3050-0714WOS: 000379614000014PubMed: 27158804Purpose:To assess the neutrophil-to-lymphocyte ratio (NLR) as an indicator of inflammation in patients with non-Sjogren dry eye disease.Methods:Serum NLR and C-reactive protein values were determined in 33 patients with dry eye and in 32 controls. the NLR was calculated by dividing the neutrophil count by the lymphocyte count.Results:Characteristics of the dry eye and control groups were similar. the mean NLR value was 2.8 1.4 (range: 1.1-6.1) in the dry eye group and 1.6 +/- 0.7 (range: 0.8-2.8) in the control group (P = 0.002, t test). the mean C-reactive protein value was 0.6 +/- 0.7 mg/dL (range: 0-2.3 mg/dL) in the dry eye group and 0.5 +/- 0.6 mg/dL (range: 0-1.9 mg/dL) in the control group (P = 0.307, t test).Conclusions:The NLR values were found to be higher in patients with non-Sjogren dry eye than in controls. This result suggests that non-Sjogren dry eye disease may be associated with systemic inflammation or the NLR values may increase in local inflammatory ocular diseases

Synthesis and Anticancer Activity of Novel Derivatives of α,β-Unsaturated Ketones Based on Oleanolic Acid: in Vitro and in Silico Studies against Prostate Cancer Cells

Herein, new derivatives of α,β-unsaturated ketones based on oleanolic acid (4 a–i) were designed, synthesized, characterized, and tested against human prostate cancer (PC3). According to the in vitro cytotoxic study, title compounds (4 a–i) showed significantly lower toxicity toward healthy cells (HUVEC) in comparison with the reference drug doxorubicin. The compounds with the lowest IC50 values on PC3 cell lines were 4 b (7.785 μM), 4 c (8.869 μM), and 4 e (8.765 μM). The results of the ADME calculations showed that the drug-likeness parameters were within the defined ranges according to Lipinski's and Jorgensen's rules. For the most potent compounds 4 b, 4 c, and 4 e, a molecular docking analysis using the induced fit docking (IFD) protocol was performed against three protein targets (PARP, PI3K, and mTOR). Based on the IFD scores, compound 4 b had the highest calculated affinity for PARP1, while compound 4 c had higher affinities for mTOR and PI3K. The MM-GBSA calculations showed that the most potent compounds had high binding affinities and formed stable complexes with the protein targets. Finally, a 50 ns molecular dynamics simulation was performed to study the behavior of protein target complexes under in silico physiological conditions

Türkiye'de sözlük ve sözlükçülük tarihi

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2018.This work is a student project of the Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.The History of Turkey course (HIST200) is a requirement for all Bilkent undergraduates. It is designed to encourage students to work in groups on projects concerning any topic of their choice that relates to the history of Turkey. It is designed as an interactive course with an emphasis on research and the objective of investigating events, chronologically short historical periods, as well as historic representations. Students from all departments prepare and present final projects for examination by a committee, with 10 projects chosen to receive awards.Includes bibliographical references (page 21).by Turaç Hakalmaz