178 research outputs found

    Knowledge acquisition and mechanically task generation for a virtual kitchenrobot

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    Inhalt dieser Arbeit ist die Entwicklung eines Software Agenten, der auf Basis des WWW Wissen akquiriert, extrahiert und dieses so aufbereitet, dass es maschinell weiter zu verarbeiten ist. Eine Task Sprache, die gesammelte Daten entsprechend aufbereitet, soll gefunden, entwickelt und beispielhaft verwendet werden. Diese Task Sprache soll als Meta-Sprache für Roboter so zu verwenden sein, dass sie in einem Roboter in ausführbaren Code umgewandelt wird und dieser die enthaltenen Arbeitsschritte mit vorhandenen Materialien und Arbeitsgeräten durchführen kann.Topic of this thesis is the devolpment of a software agent who can aquire new knowlegde on base of the world wide web, extract it and prepare it for machanically work. A task definition language should be found, researched and used in an example. The task language should be used as a meta language for a robot so that it can translate the meta language into executable code so that it can do all tasks on its own with given material und maschines

    Neuroscience of Exercise: Neuroplasticity and Its Behavioral Consequences

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    The human brain adapts to changing demands by altering itsfunctional and structural properties (neuroplasticity) whichresults in learning and acquiring skills. Convergent evidencefrom both human and animal studies suggests that enhancedphysical exercise facilitates neuroplasticity of certain brainstructures and as a result cognitive functions [1] as well asaffective [2] and behavioral responses [3].This special issue isbeing proposed at a very challenging time. There is evidencelinking increased physical exercise with an enhancement ofneurogenesis, synaptogenesis, angiogenesis, and the releaseof neurotrophins as well as neuroendocrinological changes,which are associated with benefits in cognitive and affectiveas well as behavioral functioning (such as fine motor functioning)

    Mental health and social isolation under repeated mild lockdowns in Japan

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    The influence of repeated lockdowns on mental health and social isolation is unknown. We conducted a longitudinal study of the influence of repeated mild lockdowns during two emergency declarations in Japan, in May 2020 and February 2021. The analyses included 7893 people who participated in all online surveys. During repeated mild lockdowns, mental and physical symptoms decreased overall, while loneliness increased and social networks decreased. Subgroup analyses revealed that depression and suicidal ideation did not decrease only in the younger age group (aged 18–29 years) and that younger and middle-aged people (aged 18–49 years), women, people with a history of treatment for mental illness, and people who were socially disadvantaged in terms of income had higher levels of mental and physical symptoms at all survey times. Additionally, comprehensive extraction of the interaction structure between depression, demographic attributes, and psychosocial variables indicated that loneliness and social networks were most closely associated with depression. These results indicate that repeated lockdowns have cumulative negative effects on social isolation and loneliness and that susceptible populations, such as young people and those with high levels of loneliness, require special consideration during repeated lockdown situations

    Neuroscience of Exercise: Neuroplasticity and Its Behavioral Consequences

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    The human brain adapts to changing demands by altering its functional and structural properties (neuroplasticity) which results in learning and acquiring skills. Convergent evidence from both human and animal studies suggests that enhanced physical exercise facilitates neuroplasticity of certain brain structures and as a result cognitive functions [1] as well as affective [2] and behavioral responses [3]. This special issue is being proposed at a very challenging time. There is evidence linking increased physical exercise with an enhancement of neurogenesis, synaptogenesis, angiogenesis, and the release of neurotrophins as well as neuroendocrinological changes, which are associated with benefits in cognitive and affective as well as behavioral functioning (such as fine motor functioning).Peer Reviewe

    Physical Exercise for Elderly Against Covid-19

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    Physical exercise is seen as the main ally for health promotion, preventing and protecting the organism from several diseases. According to WHO, there is a tendency of constant growth in the elderly population in the coming years. The regular practice of exercises by the elderly becomes relevant to minimize the deleterious effects of the aging process and to increase the fitness index. Recently, the world population started a confrontation against Corona Virus Disease (COVID-19), which is the most significant public health challenge globally. Although social isolation is a reasonable measure in an attempt to stop contamination by COVID-19, this measure has limited the ability of individuals to exercise outdoors or in gyms and health clubs, which increased the risk of developing chronic illnesses related to a sedentary lifestyle. The critical point is that the recent recommendations on exercise prescription to combat the potentially harmful effects of COVID-19 failure to adequately address resistance exercise interventions as home-based exercise strategy. Thus, in this paper, we discussed the physical exercise as medicine if the training status is enough to protect the elderly against COVID-19 infection, about the role of physical activity on immunosuppression. Possible risks for COVID-19 infection, and the old training methods, such as no-load resistance training as possible resistance exercise strategies and high-intensity interval training, as new proposals of home-based exercise interventions, could perform during the current COVID-19 pandemic

    Clinical results of the Metha short hip stem: a perspective for younger patients?

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    In recent years, various uncemented proximal metaphyseal hip stems were introduced for younger patients as a bone preserving strategy. Initial osteodensitometric analyses of the surrounding bone of short stems indicate an increase of bone mass with secondary bone ingrowth fixation as a predictor of long-term survival of these types of implants. We report the outcome of 151 modular Metha short hip stem implants in 148 patients between March 2005 and October 2007. The mean follow-up was 5.8±0.7 years and the mean age of the patients was 55.7±9.8 years. Along with demographic data and co-morbidities, the Harris Hip Score (HHS), the Hip dysfunction and Osteoarthritis Outcome Score (HOOS), and also the results of a patient-administered questionnaire were recorded pre-operatively and at follow-up. The mean HHS increased from 46±17 pre-operatively to 90±5 the HOOS improved from 55±16 pre-operatively to 89±10 at the final follow-up. A total of three patients have been revised, two for subsidence with femoral revision and one for infection without femoral revision (Kaplan Meier survival estimate 98%). The radiological findings showed no radiolucent lines in any of the patients. The modular Metha short hip stem was implanted in younger patients, who reported an overall high level of satisfaction. The clinical and radiographic results give support to the principle of using short stems with metaphyseal anchorage. However, long-term results are necessary to confirm the success of this concept in the years to come

    Role of N-Arachidonoyl-Serotonin (AA-5-HT) in Sleep-Wake Cycle Architecture, Sleep Homeostasis, and Neurotransmitters Regulation

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    The endocannabinoid system comprises several molecular entities such as endogenous ligands [anandamide (AEA) and 2-arachidonoylglycerol (2-AG)], receptors (CB1 and CB2), enzymes such as [fatty acid amide hydrolase (FAHH) and monoacylglycerol lipase (MAGL)], as well as the anandamide membrane transporter. Although the role of this complex neurobiological system in the sleep–wake cycle modulation has been studied, the contribution of the blocker of FAAH/transient receptor potential cation channel subfamily V member 1 (TRPV1), N-arachidonoyl-serotonin (AA-5-HT) in sleep has not been investigated. Thus, in the present study, varying doses of AA-5-HT (5, 10, or 20 mg/Kg, i.p.) injected at the beginning of the lights-on period of rats, caused no statistical changes in sleep patterns. However, similar pharmacological treatment given to animals at the beginning of the dark period decreased wakefulness (W) and increased slow wave sleep (SWS) as well as rapid eye movement sleep (REMS). Power spectra analysis of states of vigilance showed that injection of AA-5-HT during the lights-off period diminished alpha spectrum across alertness in a dose-dependent fashion. In opposition, delta power spectra was enhanced as well as theta spectrum, during SWS and REMS, respectively. Moreover, the highest dose of AA-5-HT decreased wake-related contents of neurotransmitters such as dopamine (DA), norepinephrine (NE), epinephrine (EP), serotonin (5-HT) whereas the levels of adenosine (AD) were enhanced. In addition, the sleep-inducing properties of AA-5-HT were confirmed since this compound blocked the increase in W caused by stimulants such as cannabidiol (CBD) or modafinil (MOD) during the lights-on period. Additionally, administration of AA-5-HT also prevented the enhancement in contents of DA, NE, EP, 5-HT and AD after CBD of MOD injection. Lastly, the role of AA-5-HT in sleep homeostasis was tested in animals that received either CBD or MOD after total sleep deprivation (TSD). The injection of CBD or MOD increased alertness during sleep rebound period after TSD. However, AA-5-HT blocked this effect by allowing animals to display an enhancement in sleep across sleep rebound period. Overall, our findings provide evidence that AA-5-HT is an important modulator of sleep, sleep homeostasis and neurotransmitter contents
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