THE INCORPORATION OF TRITIUM FROM THYMIDINE INTO PROTEINS OF THE MOUSE

Tritium from methyl-H3-thymidine was found to be incorporated into proteins in mice. This incorporation in the mouse as a whole represented between 1 and 10% of the injected tritium. Tritiated water was not an intermediate. Transmethylation reactions are proposed as a means whereby certain amino acids might have acquired the tritium from thymidine at some stage of its catabolism. The initial (2 hr) ratios of DNA to protein tritium activities per milligram of wet tissue ranged from 5 in two tissues of low DNA synthetic activity (pancreas, liver) to 35 to 40 in two tissues of high DNA synthetic activity (spleen, small intestine). Labeled nuclear protein was coincident with labeled DNA in nuclei, where it constituted less than 2.5% of the total tritium. The significance of the findings is discussed

Optical/Infrared Observations of the Anomalous X-ray Pulsar 1E 1048.1-5937 During Its 2007 X-Ray Flare

We report on optical and infrared observations of the anomalous X-ray pulsar (AXP) 1E 1048.1-5937, made during its ongoing X-ray flare which started in 2007 March. We detected the source in the optical I and near-infrared Ks bands in two ground-based observations and obtained deep flux upper limits from four observations, including one with the Spitzer Space Telescope at 4.5 and 8.0 microns. The detections indicate that the source was approximately 1.3--1.6 magnitudes brighter than in 2003--2006, when it was at the tail of a previous similar X-ray flare. Similar related flux variations have been seen in two other AXPs during their X-ray outbursts, suggesting common behavior for large X-ray flux variation events in AXPs. The Spitzer flux 1E 1048.1-5937 limits are sufficiently deep that we can exclude mid-infrared emission similar to that from the AXP 4U 0142+61, which has been interpreted as arising from a dust disk around the AXP. The optical/near-infrared emission from probably has a magnetospheric origin. The similarity in the flux spectra of 4U 0142+61 and 1E 1048.1-5937 challenges the dust disk model proposed for the latter.Comment: 5 pages, 1 figure, accepted by Ap

An ultra-compact low temperature scanning probe microscope for magnetic fields above 30 T

We present the design of a highly compact High Field Scanning Probe Microscope (HF-SPM) for operation at cryogenic temperatures in an extremely high magnetic field, provided by a water-cooled Bitter magnet able to reach 38 T. The HF-SPM is 14 mm in diameter: an Attocube nano-positioner controls the coarse approach of a piezo resistive AFM cantilever to a scanned sample. The Bitter magnet constitutes an extreme environment for SPM due to the high level of vibrational noise; the Bitter magnet noise at frequencies up to 300 kHz is characterized and noise mitigation methods are described. The performance of the HF-SPM is demonstrated by topographic imaging and noise measurements at up to 30 T. Additionally, the use of the SPM as a three-dimensional dilatometer for magnetostriction measurements is demonstrated via measurements on a magnetically frustrated spinel sample.Comment: 6 pages, 5 figure

Controlled complete suppression of single-atom inelastic spin and orbital cotunnelling

The inelastic portion of the tunnel current through an individual magnetic atom grants unique access to read out and change the atom's spin state, but it also provides a path for spontaneous relaxation and decoherence. Controlled closure of the inelastic channel would allow for the latter to be switched off at will, paving the way to coherent spin manipulation in single atoms. Here we demonstrate complete closure of the inelastic channels for both spin and orbital transitions due to a controlled geometric modification of the atom's environment, using scanning tunnelling microscopy (STM). The observed suppression of the excitation signal, which occurs for Co atoms assembled into chain on a Cu$_2$N substrate, indicates a structural transition affecting the d$_z$$^2$ orbital, effectively cutting off the STM tip from the spin-flip cotunnelling path.Comment: 4 figures plus 4 supplementary figure

Software Tools for Developing and Simulating the NASA LaRC CMF Motion Base

The NASA Langley Research Center (LaRC) Cockpit Motion Facility (CMF) motion base has provided many design and analysis challenges. In the process of addressing these challenges, a comprehensive suite of software tools was developed. The software tools development began with a detailed MATLAB/Simulink model of the motion base which was used primarily for safety loads prediction, design of the closed loop compensator and development of the motion base safety systems1. A Simulink model of the digital control law, from which a portion of the embedded code is directly generated, was later added to this model to form a closed loop system model. Concurrently, software that runs on a PC was created to display and record motion base parameters. It includes a user interface for controlling time history displays, strip chart displays, data storage, and initializing of function generators used during motion base testing. Finally, a software tool was developed for kinematic analysis and prediction of mechanical clearances for the motion system. These tools work together in an integrated package to support normal operations of the motion base, simulate the end to end operation of the motion base system providing facilities for software-in-the-loop testing, mechanical geometry and sensor data visualizations, and function generator setup and evaluation

Two universal results for Wilson loops at strong coupling

We present results for Wilson loops in strongly coupled gauge theories. The loops may be taken around an arbitrarily shaped contour and in any field theory with a dual IIB geometry of the form M x S^5. No assumptions about supersymmetry are made. The first result uses D5 branes to show how the loop in any antisymmetric representation is computed in terms of the loop in the fundamental representation. The second result uses D3 branes to observe that each loop defines a rich sequence of operators associated with minimal surfaces in S^5. The action of these configurations are all computable. Both results have features suggesting a connection with integrability.Comment: 1+12 pages. LaTeX. No figure

Development and Validation of a Facebook Relational Maintenance Measure

This manuscript details the construction of a measure of Facebook relational maintenance behaviors. The first study generated an item pool by drawing from previous qualitative investigations and adapting an established relational maintenance scale. Participants were then invited to evaluate these items in order to establish face validity. During study two, participants were asked how often they used the behaviors represented in these items to maintain a specific friendship. Exploratory factor analysis was conducted to determine the underlying structure of these items; three latent factors emerged, social contact, response-seeking, and relational assurances. This factor structure was then assessed using confirmatory factor analysis during phase three. Study three participants were also asked to complete measures of friendship quality, Facebook intensity, and online social communication. The relationship of the three factors of Facebook relational maintenance to friendship quality, Facebook intensity, and online social communication suggests convergent and discriminant validity for the Facebook relational maintenance measure